Published in Proc Natl Acad Sci U S A on October 01, 1988
Recombination within natural populations of pathogenic bacteria: short-term empirical estimates and long-term phylogenetic consequences. Proc Natl Acad Sci U S A (2001) 7.90
Common themes in microbial pathogenicity. Microbiol Rev (1989) 7.78
Genetic characterization of clones of the bacterium Listeria monocytogenes causing epidemic disease. Proc Natl Acad Sci U S A (1989) 5.00
Characterization of encapsulated and noncapsulated Haemophilus influenzae and determination of phylogenetic relationships by multilocus sequence typing. J Clin Microbiol (2003) 4.47
Identification of a high-virulence clone of type III Streptococcus agalactiae (group B Streptococcus) causing invasive neonatal disease. Proc Natl Acad Sci U S A (1989) 3.66
Use of coagulase gene (coa) repeat region nucleotide sequences for typing of methicillin-resistant Staphylococcus aureus strains. J Clin Microbiol (2000) 2.33
Capsulation in distantly related strains of Haemophilus influenzae type b: genetic drift and gene transfer at the capsulation locus. J Bacteriol (1990) 1.98
Common organization of chromosomal loci for production of different capsular polysaccharides in Haemophilus influenzae. J Bacteriol (1989) 1.96
Prevalence and distribution of the hmw and hia genes and the HMW and Hia adhesins among genetically diverse strains of nontypeable Haemophilus influenzae. Infect Immun (1998) 1.94
Characterization of the genetic locus encoding Haemophilus influenzae type b surface fibrils. J Bacteriol (1996) 1.81
Population structure of Streptococcus agalactiae reveals an association between specific evolutionary lineages and putative virulence factors but not disease. Infect Immun (1996) 1.68
Copper-zinc superoxide dismutase of Haemophilus influenzae and H. parainfluenzae. J Bacteriol (1991) 1.59
Molecular conservation of the P6 outer membrane protein among strains of Haemophilus influenzae: analysis of antigenic determinants, gene sequences, and restriction fragment length polymorphisms. Infect Immun (1991) 1.49
Evidence for absence in northern Europe of especially virulent clonal types of Actinobacillus actinomycetemcomitans. J Clin Microbiol (1995) 1.45
Genetic characterization of a cryptic genospecies of Haemophilus causing urogenital and neonatal infections. J Clin Microbiol (1993) 1.41
Analysis of genetic relatedness of Haemophilus influenzae isolates by multilocus sequence typing. J Bacteriol (2007) 1.41
The tryptophanase gene cluster of Haemophilus influenzae type b: evidence for horizontal gene transfer. J Bacteriol (1998) 1.40
Variability of outer membrane protein P1 and its evaluation as a vaccine candidate against experimental otitis media due to nontypeable Haemophilus influenzae: an unambiguous, multifaceted approach. Infect Immun (2000) 1.36
Increase in genetic diversity of Haemophilus influenzae serotype b (Hib) strains after introduction of Hib vaccination in The Netherlands. J Clin Microbiol (2005) 1.33
Delineation of the species Haemophilus influenzae by phenotype, multilocus sequence phylogeny, and detection of marker genes. J Bacteriol (2008) 1.30
Evolution of the major pilus gene cluster of Haemophilus influenzae. J Bacteriol (1998) 1.28
Classification, identification, and clinical significance of haemophilus and aggregatibacter species with host specificity for humans. Clin Microbiol Rev (2014) 1.20
Genetic diversity of Gallibacterium anatis isolates from different chicken flocks. J Clin Microbiol (2003) 1.14
Genetic analysis of the capsule locus of Haemophilus influenzae serotype f. Infect Immun (2003) 1.07
Comparative analysis of the structures of the outer membrane protein P1 genes from major clones of Haemophilus influenzae type b. Infect Immun (1989) 1.05
Complete sequence of the cap locus of Haemophilus influenzae serotype b and nonencapsulated b capsule-negative variants. Infect Immun (2003) 1.05
Low genetic diversity of Haemophilus influenzae type b compared to nonencapsulated H. influenzae in a population in which H. influenzae is highly endemic. Infect Immun (1998) 0.96
Evolutionary genetics of Pasteurella haemolytica isolates recovered from cattle and sheep. Infect Immun (1997) 0.96
Haemocin, the bacteriocin produced by Haemophilus influenzae: species distribution and role in colonization. Infect Immun (1990) 0.94
Active copper- and zinc-containing superoxide dismutase in the cryptic genospecies of Haemophilus causing urogenital and neonatal infections discriminates them from Haemophilus influenzae sensu stricto. J Clin Microbiol (2002) 0.94
Immunogenicity of overlapping synthetic peptides covering the entire sequence of Haemophilus influenzae type b outer membrane protein P2. Infect Immun (1993) 0.92
Nucleotide sequence diversity of the bexA gene in serotypeable Haemophilus influenzae strains recovered from invasive disease patients in Canada. J Clin Microbiol (2007) 0.91
Insertion sequence IS1016 and absence of Haemophilus capsulation genes in the Brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius. Infect Immun (1992) 0.90
Identification and genetic characterization of Haemophilus influenzae genetic island 1. Infect Immun (2000) 0.88
Population structure in nontypeable Haemophilus influenzae. Infect Genet Evol (2012) 0.87
Antigenic relationships among the porin proteins of encapsulated Haemophilus influenzae clones. J Clin Microbiol (1990) 0.86
Laboratory characterization of invasive Haemophilus influenzae isolates from Nunavut, Canada, 2000-2012. Int J Circumpolar Health (2016) 0.85
Identification of Haemophilus influenzae clones associated with invasive disease a decade after introduction of H. influenzae serotype b vaccination in Italy. Clin Vaccine Immunol (2013) 0.83
Population subdivision and the detection of recombination in non-typable Haemophilus influenzae. Microbiology (2012) 0.82
Identification of Haemophilus influenzae Type b Isolates by Use of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry. J Clin Microbiol (2015) 0.77
Epidemiological typing of Moraxella catarrhalis by pulsed field gel electrophoresis. Can J Infect Dis (1995) 0.75
Genotyping of Haemophilus influenzae type b strains and their incidence in the clinical samples isolated from Iranian patients. Iran J Microbiol (2015) 0.75
Methods of multilocus enzyme electrophoresis for bacterial population genetics and systematics. Appl Environ Microbiol (1986) 24.31
A taxonomic study of the genus Haemophilus, with the proposal of a new species. J Gen Microbiol (1976) 17.88
Genetic relationships of serologically nontypable and serotype b strains of Haemophilus influenzae. Infect Immun (1986) 5.92
Population genetics of pathogenic bacteria. Microb Pathog (1987) 5.59
The pathogenicity of Haemophilus influenzae. J Med Microbiol (1984) 5.37
Genetic structure of Neisseria meningitidis populations in relation to serogroup, serotype, and outer membrane protein pattern. J Bacteriol (1987) 5.30
Genetic diversity and relationships in populations of Bordetella spp. J Bacteriol (1986) 4.48
A population genetic framework for the study of invasive diseases caused by serotype b strains of Haemophilus influenzae. Proc Natl Acad Sci U S A (1985) 4.48
Genetic diversity in relation to serotype in Escherichia coli. Infect Immun (1985) 4.11
The type b capsular polysaccharide as a virulence determinant of Haemophilus influenzae: studies using clinical isolates and laboratory transformants. J Infect Dis (1981) 3.24
Clonal population structure of encapsulated Haemophilus influenzae. Infect Immun (1988) 3.03
Cloning of chromosomal DNA from Haemophilus influenzae. Its use for studying the expression of type b capsule and virulence. J Clin Invest (1984) 2.94
Genetics of spontaneous, high-frequency loss of b capsule expression in Haemophilus influenzae. Infect Immun (1985) 2.84
Clonal diversity and host distribution in Bordetella bronchiseptica. J Bacteriol (1987) 2.59
Capsule loss in H. influenzae type b occurs by recombination-mediated disruption of a gene essential for polysaccharide export. Cell (1988) 2.49
Clonal diversity in Haemophilus pleuropneumoniae. Infect Immun (1987) 1.78
Molecular biology of Haemophilus influenzae IgA1 proteases. Mol Immunol (1983) 1.44
Limited genetic diversity of Haemophilus influenzae (type b). Microb Pathog (1987) 1.44
Relationship between the specificity of IgA proteases and serotypes in Haemophilus influenzae. J Infect Dis (1982) 1.36
A chemotyping scheme for clinical isolates of Haemophilus influenzae. J Med Microbiol (1984) 1.20
Outer membrane protein subtypes and biotypes of Haemophilus influenzae type b: relation between strains isolated in 1934-1954 and 1977-1980. J Infect Dis (1983) 1.20
Structural studies of the capsular polysaccharide from Haemophilus pleuropneumoniae serotype 1. Biochem Cell Biol (1986) 1.13
Physical and genetic analysis of DNA regions encoding the immunoglobulin A proteases of different specificities produced by Haemophilus influenzae. Infect Immun (1985) 1.05
Non-type b Haemophilus influenzae meningitis. Lancet (1985) 1.03
Haemophilus influenzae serotype a: outer membrane protein classification and correlation with DNA polymorphism at the cap locus. Infect Immun (1988) 1.00
Identification of Haemophilus influenzae type b by a monoclonal antibody coagglutination assay. J Clin Microbiol (1987) 0.94
Biochemical differentiation of Haemophilus influenzae. Additional characterization of biotypes by carbohydrate fermentation patterns. Zentralbl Bakteriol Mikrobiol Hyg A (1982) 0.85
Methods of multilocus enzyme electrophoresis for bacterial population genetics and systematics. Appl Environ Microbiol (1986) 24.31
Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. Science (2000) 16.04
Genetic diversity and structure in Escherichia coli populations. Science (1980) 11.19
Standard reference strains of Escherichia coli from natural populations. J Bacteriol (1984) 11.16
The gal locus from Haemophilus influenzae: cloning, sequencing and the use of gal mutants to study lipopolysaccharide. Mol Microbiol (1992) 9.22
Resolution of recent evolutionary divergence among Escherichia coli from related lineages: the application of pulsed field electrophoresis to molecular epidemiology. J Infect Dis (1990) 8.33
Multilocus genetic structure in natural populations of Escherichia coli. Proc Natl Acad Sci U S A (1983) 7.42
Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing. Science (2000) 7.41
Genetic diversity and temporal variation in the E. coli population of a human host. Genetics (1981) 7.35
Genetic structure of populations of Legionella pneumophila. J Bacteriol (1985) 7.30
Enzyme polymorphism and genetic population structure in Escherichia coli and Shigella. J Gen Microbiol (1983) 7.28
Parallel evolution of virulence in pathogenic Escherichia coli. Nature (2000) 6.25
Genetic relationships of serologically nontypable and serotype b strains of Haemophilus influenzae. Infect Immun (1986) 5.92
Molecular genetic relationships of the salmonellae. Appl Environ Microbiol (1996) 5.66
Detection of Pneumocystis carinii with DNA amplification. Lancet (1990) 5.50
Streptococcus pyogenes causing toxic-shock-like syndrome and other invasive diseases: clonal diversity and pyrogenic exotoxin expression. Proc Natl Acad Sci U S A (1991) 5.46
Intercontinental spread of a genetically distinctive complex of clones of Neisseria meningitidis causing epidemic disease. Proc Natl Acad Sci U S A (1986) 5.39
Genetic structure of Neisseria meningitidis populations in relation to serogroup, serotype, and outer membrane protein pattern. J Bacteriol (1987) 5.30
Evidence for clonal population structure in Escherichia coli. Proc Natl Acad Sci U S A (1984) 5.08
Genetic characterization of clones of the bacterium Listeria monocytogenes causing epidemic disease. Proc Natl Acad Sci U S A (1989) 5.00
Haemophilus influenzae meningitis in infant rats after intranasal inoculation. J Infect Dis (1974) 4.94
Production of Haemophilus influenzae b meningitis in infant rats by intraperitoneal inoculation. Infect Immun (1973) 4.80
Evolutionary genetics of the proline permease gene (putP) and the control region of the proline utilization operon in populations of Salmonella and Escherichia coli. J Bacteriol (1992) 4.50
Genetic diversity and relationships in populations of Bordetella spp. J Bacteriol (1986) 4.48
A population genetic framework for the study of invasive diseases caused by serotype b strains of Haemophilus influenzae. Proc Natl Acad Sci U S A (1985) 4.48
Geographic components of linkage disequilibrium in natural populations of Escherichia coli. Mol Biol Evol (1983) 4.11
Genetic diversity in relation to serotype in Escherichia coli. Infect Immun (1985) 4.11
PCR for capsular typing of Haemophilus influenzae. J Clin Microbiol (1994) 4.08
Global genetic structure and molecular epidemiology of encapsulated Haemophilus influenzae. Rev Infect Dis (1990) 4.06
Nucleotide polymorphism and evolution in the glyceraldehyde-3-phosphate dehydrogenase gene (gapA) in natural populations of Salmonella and Escherichia coli. Proc Natl Acad Sci U S A (1991) 3.97
Molecular genetic basis of allelic polymorphism in malate dehydrogenase (mdh) in natural populations of Escherichia coli and Salmonella enterica. Proc Natl Acad Sci U S A (1994) 3.90
Salmonella reference collection B (SARB): strains of 37 serovars of subspecies I. J Gen Microbiol (1993) 3.85
A single clone of Staphylococcus aureus causes the majority of cases of toxic shock syndrome. Proc Natl Acad Sci U S A (1990) 3.76
Vaccine failures after primary immunisation with Haemophilus influenzae type-b conjugate vaccine without booster. Lancet (1997) 3.69
Identification of a high-virulence clone of type III Streptococcus agalactiae (group B Streptococcus) causing invasive neonatal disease. Proc Natl Acad Sci U S A (1989) 3.66
Immunogenicity of combined diphtheria, tetanus, and pertussis vaccine given at 2, 3, and 4 months versus 3, 5, and 9 months of age. Lancet (1992) 3.60
The molecular mechanism of phase variation of H. influenzae lipopolysaccharide. Cell (1989) 3.60
Genetic relationships and clonal structure of strains of Escherichia coli causing neonatal septicemia and meningitis. Infect Immun (1986) 3.57
Protein polymorphism and genic heterozygosity in a wild population of the house mouse (Mus musculus). Genetics (1969) 3.40
DNA repeats identify novel virulence genes in Haemophilus influenzae. Proc Natl Acad Sci U S A (1996) 3.38
Sequence invariance of the antigen-coding central region of the phase 1 flagellar filament gene (fliC) among strains of Salmonella typhimurium. J Bacteriol (1990) 3.33
Relationship between evolutionary rate and cellular location among the Inv/Spa invasion proteins of Salmonella enterica. Proc Natl Acad Sci U S A (1995) 3.32
The type b capsular polysaccharide as a virulence determinant of Haemophilus influenzae: studies using clinical isolates and laboratory transformants. J Infect Dis (1981) 3.24
Genetic diversity and relationships among strains of Escherichia coli in the intestine and those causing urinary tract infections. Prog Allergy (1983) 3.12
Clonal population structure of encapsulated Haemophilus influenzae. Infect Immun (1988) 3.03
Reference collection of strains of the Salmonella typhimurium complex from natural populations. J Gen Microbiol (1991) 3.00
Genetic diversity and relationships among isolates of Rhizobium leguminosarum biovar phaseoli. Appl Environ Microbiol (1988) 2.98
Cloning of chromosomal DNA from Haemophilus influenzae. Its use for studying the expression of type b capsule and virulence. J Clin Invest (1984) 2.94
Virulence and transmissibility of pathogens: what is the relationship? Trends Microbiol (1997) 2.91
Population-based study of non-typable Haemophilus influenzae invasive disease in children and neonates. Lancet (1993) 2.88
Behavior and genetic variation in natural populations. Am Zool (1970) 2.86
Genetics of spontaneous, high-frequency loss of b capsule expression in Haemophilus influenzae. Infect Immun (1985) 2.84
Genetic structure of natural populations of the nitrogen-fixing bacterium Rhizobium meliloti. Appl Environ Microbiol (1990) 2.84
Recombination of Salmonella phase 1 flagellin genes generates new serovars. J Bacteriol (1990) 2.80
Genetic diversity and relationships of two pathovars of Pseudomonas syringae. J Gen Microbiol (1988) 2.80
Simple sequence repeats in the Helicobacter pylori genome. Mol Microbiol (1998) 2.75
HIV-specific cytotoxic T-cell activity in an HIV-exposed but uninfected infant. Lancet (1993) 2.71
Clonal diversity and host distribution in Bordetella bronchiseptica. J Bacteriol (1987) 2.59
The bex locus in encapsulated Haemophilus influenzae: a chromosomal region involved in capsule polysaccharide export. Mol Microbiol (1990) 2.49
Capsule loss in H. influenzae type b occurs by recombination-mediated disruption of a gene essential for polysaccharide export. Cell (1988) 2.49
Molecular evolution and mosaic structure of alpha, beta, and gamma intimins of pathogenic Escherichia coli. Mol Biol Evol (1999) 2.44
Repeat-associated phase variable genes in the complete genome sequence of Neisseria meningitidis strain MC58. Mol Microbiol (2000) 2.44
Amplification of mitochondrial ribosomal RNA sequences from Pneumocystis carinii DNA of rat and human origin. Mol Biochem Parasitol (1990) 2.42
Shared themes of antigenic variation and virulence in bacterial, protozoal, and fungal infections. Microbiol Mol Biol Rev (1997) 2.42
Ampicillin treatment failure of apparently beta-lactamase-negative Haemophilus influenzae type b meningitis due to novel beta-lactamase. Lancet (1981) 2.41
Pathogenesis of neonatal Escherichia coli meningitis: induction of bacteremia and meningitis in infant rats fed E. coli K1. Infect Immun (1977) 2.39
The role of pili in the interactions of pathogenic Neisseria with cultured human endothelial cells. Mol Microbiol (1991) 2.36
Recombinational basis of serovar diversity in Salmonella enterica. Proc Natl Acad Sci U S A (1994) 2.35
Paleoepidemiologic investigation of Legionnaires disease at Wadsworth Veterans Administration Hospital by using three typing methods for comparison of legionellae from clinical and environmental sources. J Clin Microbiol (1986) 2.34
The impact of conjugate vaccine on carriage of Haemophilus influenzae type b. J Infect Dis (1995) 2.31
Elephant seals: genetic variation and near extinction. Science (1974) 2.29
Clonal analysis of Escherichia coli O2:K1 isolated from diseased humans and animals. Infect Immun (1986) 2.27
Meningococcal Opa and Opc proteins: their role in colonization and invasion of human epithelial and endothelial cells. Mol Microbiol (1993) 2.26
Intergeneric transfer and recombination of the 6-phosphogluconate dehydrogenase gene (gnd) in enteric bacteria. Proc Natl Acad Sci U S A (1994) 2.26
Bacterial copper- and zinc-cofactored superoxide dismutase contributes to the pathogenesis of systemic salmonellosis. Mol Microbiol (1997) 2.23
Detection and quantitation of bacteremia in childhood. J Pediatr (1977) 2.21
The role of bacterial polysaccharide capsules as virulence factors. Curr Top Microbiol Immunol (1990) 2.18
Opc- and pilus-dependent interactions of meningococci with human endothelial cells: molecular mechanisms and modulation by surface polysaccharides. Mol Microbiol (1995) 2.18
Clonal diversity of Neisseria meningitidis from a population of asymptomatic carriers. Infect Immun (1988) 2.14
Characterization of Streptococcus agalactiae strains by multilocus enzyme genotype and serotype: identification of multiple virulent clone families that cause invasive neonatal disease. J Clin Microbiol (1995) 2.13
The length of a tetranucleotide repeat tract in Haemophilus influenzae determines the phase variation rate of a gene with homology to type III DNA methyltransferases. Mol Microbiol (2000) 2.13
Distribution of multilocus genotypes of Escherichia coli within and between host families. J Hyg (Lond) (1984) 2.10
Haemophilus influenzae meningitis in infant rats: role of bacteremia in pathogenesis of age-dependent inflammatory responses in cerebrospinal fluid. J Infect Dis (1977) 2.09
Characterization of repetitive sequences controlling phase variation of Haemophilus influenzae lipopolysaccharide. J Bacteriol (1990) 2.08
Safety, immunogenicity, and induction of immunologic memory by a serogroup C meningococcal conjugate vaccine in infants: A randomized controlled trial. JAMA (2000) 2.07
Legionella pneumophila serogroup Lansing 3 isolated from a patient with fatal pneumonia, and descriptions of L. pneumophila subsp. pneumophila subsp. nov., L. pneumophila subsp. fraseri subsp. nov., and L. pneumophila subsp. pascullei subsp. nov. J Clin Microbiol (1988) 2.06
Surface determinants of Haemophilus influenzae pathogenicity: comparative virulence of capsular transformants in normal and complement-depleted rats. J Infect Dis (1983) 2.06
The simple sequence contingency loci of Haemophilus influenzae and Neisseria meningitidis. J Clin Invest (2001) 2.04
Genetic relationships and clonal population structure of serotype 2 strains of Neisseria meningitidis. Infect Immun (1987) 2.04
The Haemophilus influenzae capsulation gene cluster: a compound transposon. Mol Microbiol (1991) 2.03
Genetic relationships among the oral streptococci. J Bacteriol (1987) 2.02
Genetic diversity and population structure of Vibrio cholerae. J Clin Microbiol (1999) 2.00
The role of a repetitive DNA motif (5'-CAAT-3') in the variable expression of the Haemophilus influenzae lipopolysaccharide epitope alpha Gal(1-4)beta Gal. Mol Microbiol (1993) 1.98
Capsulation in distantly related strains of Haemophilus influenzae type b: genetic drift and gene transfer at the capsulation locus. J Bacteriol (1990) 1.98
Common organization of chromosomal loci for production of different capsular polysaccharides in Haemophilus influenzae. J Bacteriol (1989) 1.96
Variable expression of the Opc outer membrane protein in Neisseria meningitidis is caused by size variation of a promoter containing poly-cytidine. Mol Microbiol (1994) 1.96