Published in Hum Genet on November 01, 1988
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Recently transposed Alu repeats result from multiple source genes. Nucleic Acids Res (1990) 2.10
Polymorphic DNA haplotypes at the LDL receptor locus. Am J Hum Genet (1989) 1.82
Lower-than-expected linkage disequilibrium between tightly linked markers in humans suggests a role for gene conversion. Am J Hum Genet (2001) 1.80
Amplification dynamics of human-specific (HS) Alu family members. Nucleic Acids Res (1991) 1.72
Evidence for a dominant gene that suppresses hypercholesterolemia in a family with defective low density lipoprotein receptors. J Clin Invest (1989) 1.24
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Regulation of the apolipoprotein gene cluster by a long noncoding RNA. Cell Rep (2014) 1.10
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DNA sequences of Alu elements indicate a recent replacement of the human autosomal genetic complement. Proc Natl Acad Sci U S A (1996) 0.95
Polymorphic haplotypes and recombination rates at the LDL receptor gene locus in subjects with and without familial hypercholesterolemia who are from different populations. Am J Hum Genet (1993) 0.88
Extended haplotypes and linkage disequilibrium between 11 markers at the APOA1-C3-A4 gene cluster on chromosome 11. Am J Hum Genet (1991) 0.80
Gene and gene-product variation in the apolipoprotein A-I/C-III/A-IV cluster in the Dogrib Indians of the Northwest Territories. Am J Hum Genet (1989) 0.77
High density lipoprotein deficiency with xanthomas. A defect in reverse cholesterol transport caused by a point mutation in the apolipoprotein A-I gene. J Clin Invest (1993) 0.76
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Decreased expression of the APOA1-APOC3-APOA4 gene cluster is associated with risk of Alzheimer's disease. Drug Des Devel Ther (2015) 0.75
Identification of the cystic fibrosis gene: genetic analysis. Science (1989) 33.61
Properties of a neutral allele model with intragenic recombination. Theor Popul Biol (1983) 28.09
A test of neutral molecular evolution based on nucleotide data. Genetics (1987) 24.44
Statistical properties of the number of recombination events in the history of a sample of DNA sequences. Genetics (1985) 20.92
The "hitchhiking effect" revisited. Genetics (1989) 17.72
Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. Nat Genet (1999) 17.09
Pairwise comparisons of mitochondrial DNA sequences in stable and exponentially growing populations. Genetics (1991) 16.12
Comparative analyses of multi-species sequences from targeted genomic regions. Nature (2003) 13.31
The coalescent process in models with selection. Genetics (1988) 10.14
The hitchhiking effect on the site frequency spectrum of DNA polymorphisms. Genetics (1995) 9.53
New goals for the U.S. Human Genome Project: 1998-2003. Science (1998) 8.30
Nonuniform recombination within the human beta-globin gene cluster. Am J Hum Genet (1984) 7.97
DNA duplication associated with Charcot-Marie-Tooth disease type 1A. Cell (1991) 7.93
A DNA polymorphism discovery resource for research on human genetic variation. Genome Res (1998) 7.44
Estimating the recombination parameter of a finite population model without selection. Genet Res (1987) 7.37
Gene conversion and different population histories may explain the contrast between polymorphism and linkage disequilibrium levels. Am J Hum Genet (2001) 5.84
LIAN 3.0: detecting linkage disequilibrium in multilocus data. Linkage Analysis. Bioinformatics (2000) 5.29
High-throughput variation detection and genotyping using microarrays. Genome Res (2001) 5.24
The sampling distribution of linkage disequilibrium under an infinite allele model without selection. Genetics (1985) 4.64
Inferring the evolutionary histories of the Adh and Adh-dup loci in Drosophila melanogaster from patterns of polymorphism and divergence. Genetics (1991) 4.59
Adjusting the focus on human variation. Trends Genet (2000) 4.44
Automated construction of genetic linkage maps using an expert system (MultiMap): a human genome linkage map. Nat Genet (1994) 4.19
Hirschsprung disease, associated syndromes and genetics: a review. J Med Genet (2007) 4.13
Apolipoprotein multigene family: tandem organization of human apolipoprotein AI, CIII, and AIV genes. Proc Natl Acad Sci U S A (1985) 4.04
The use of sample genealogies for studying a selectively neutral m-loci model with recombination. Theor Popul Biol (1985) 3.72
Basic fallacies in the formulation of the paternity index. Am J Hum Genet (1985) 3.18
Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21. Nat Genet (1998) 3.00
Evidence for increased recombination near the human insulin gene: implication for disease association studies. Proc Natl Acad Sci U S A (1986) 2.96
Molecular evidence for a relationship between LINE-1 elements and X chromosome inactivation: the Lyon repeat hypothesis. Proc Natl Acad Sci U S A (2000) 2.94
Estimating the prior probability of paternity from the results of exclusion tests. Forensic Sci Int (1984) 2.91
Similarity of DNA fingerprints due to chance and relatedness. Hum Hered (1993) 2.90
Hierarchical analysis of linkage disequilibrium in Rhizobium populations: evidence for sex? Proc Natl Acad Sci U S A (1992) 2.89
Parallel genotyping of human SNPs using generic high-density oligonucleotide tag arrays. Genome Res (2000) 2.79
Genetic mapping of autosomal dominant Charcot-Marie-Tooth disease in a large French-Acadian kindred: identification of new linked markers on chromosome 17. Am J Hum Genet (1990) 2.77
Malaria's Eve: evidence of a recent population bottleneck throughout the world populations of Plasmodium falciparum. Proc Natl Acad Sci U S A (1998) 2.76
Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells. Mol Cell Biol (1992) 2.72
Regulation of the apolipoprotein AI gene by ARP-1, a novel member of the steroid receptor superfamily. Science (1991) 2.70
Estimating genetic variability with restriction endonucleases. Genetics (1982) 2.68
Transesophageal echocardiographically facilitated early cardioversion from atrial fibrillation using short-term anticoagulation: final results of a prospective 4.5-year study. J Am Coll Cardiol (1995) 2.52
Patterns of polymorphism and linkage disequilibrium suggest independent origins of the human growth hormone gene cluster. Proc Natl Acad Sci U S A (1984) 2.47
Isolation and characterization of the human apolipoprotein A-I gene. Proc Natl Acad Sci U S A (1983) 2.42
Patterns of genetic variation in Mendelian and complex traits. Annu Rev Genomics Hum Genet (2000) 2.37
RNA-mediated gene duplication: the rat preproinsulin I gene is a functional retroposon. Mol Cell Biol (1985) 2.35
A genetic study of Hirschsprung disease. Am J Hum Genet (1990) 2.30
It's raining SNPs, hallelujah? Nat Genet (1998) 2.30
Evidence for reduced recombination on the nondisjoined chromosomes 21 in Down syndrome. Science (1987) 2.27
Evidence for multiple origins of the beta E-globin gene in Southeast Asia. Proc Natl Acad Sci U S A (1982) 2.24
Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide. Mol Cell Biol (1994) 2.08
Multiplex PCR of three dinucleotide repeats in the Prader-Willi/Angelman critical region (15q11-q13): molecular diagnosis and mechanism of uniparental disomy. Hum Mol Genet (1993) 2.02
Detecting linkage disequilibrium in bacterial populations. Genetics (1998) 1.89
Coalescent simulations and statistical tests of neutrality. Mol Biol Evol (2001) 1.88
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Recombination within and between the human insulin and beta-globin gene loci. Proc Natl Acad Sci U S A (1983) 1.82
Polymorphic DNA haplotypes at the LDL receptor locus. Am J Hum Genet (1989) 1.82
Allele frequency distributions in pooled DNA samples: applications to mapping complex disease genes. Genome Res (1998) 1.81
Elf-1 is a transcriptional regulator of the Tie2 gene during vascular development. Circ Res (2001) 1.81
A retinoic acid-responsive element in the apolipoprotein AI gene distinguishes between two different retinoic acid response pathways. Mol Cell Biol (1991) 1.80
An inherited polymorphism in the human apolipoprotein A-I gene locus related to the development of atherosclerosis. Nature (1983) 1.80
Mean and variance of FST in a finite number of incompletely isolated populations. Theor Popul Biol (1977) 1.79
Molecular characterization of two proximal deletion breakpoint regions in both Prader-Willi and Angelman syndrome patients. Am J Hum Genet (1995) 1.78
Germline mutations in glial cell line-derived neurotrophic factor (GDNF) and RET in a Hirschsprung disease patient. Nat Genet (1996) 1.77
A human model for multigenic inheritance: phenotypic expression in Hirschsprung disease requires both the RET gene and a new 9q31 locus. Proc Natl Acad Sci U S A (2000) 1.76
Angiopoietin-1 is expressed in the synovium of patients with rheumatoid arthritis and is induced by tumour necrosis factor alpha. Ann Rheum Dis (2003) 1.74
Reciprocal regulation of RhoA and RhoC characterizes the EMT and identifies RhoC as a prognostic marker of colon carcinoma. Oncogene (2006) 1.73
Apolipoprotein A-I gene polymorphism associated with premature coronary artery disease and familial hypoalphalipoproteinemia. N Engl J Med (1986) 1.70
To a future of genetic medicine. Nature (2001) 1.70
Parental origin and phenotype of triploidy in spontaneous abortions: predominance of diandry and association with the partial hydatidiform mole. Am J Hum Genet (2000) 1.69
ERP, a new member of the ets transcription factor/oncoprotein family: cloning, characterization, and differential expression during B-lymphocyte development. Mol Cell Biol (1994) 1.67
The meiotic stage of nondisjunction in trisomy 21: determination by using DNA polymorphisms. Am J Hum Genet (1992) 1.67
On the divergence of genes in multigene families. Theor Popul Biol (1987) 1.67
Linkage of human apolipoproteins A-I and C-III genes. Nature (1983) 1.66
Isolation and characterization of cDNA clones for human apolipoprotein A-I. Proc Natl Acad Sci U S A (1982) 1.66
Linkage disequilibrium analysis of biallelic DNA markers, human quantitative trait loci, and threshold-defined case and control subjects. Am J Hum Genet (2000) 1.65
A homozygous mutation in the endothelin-3 gene associated with a combined Waardenburg type 2 and Hirschsprung phenotype (Shah-Waardenburg syndrome). Nat Genet (1996) 1.65
Role of the Ets transcription factors in the regulation of the vascular-specific Tie2 gene. Circ Res (1999) 1.62
Multipoint gene mapping using seriation. I. General methods. Am J Hum Genet (1987) 1.61
Genetic tagging of humpback whales. Nature (1997) 1.61
Detection of tandem duplications and implications for linkage analysis. Am J Hum Genet (1994) 1.60
Microsatellite polymorphism linkage map of human chromosome 13q. Genomics (1993) 1.56
Elevated frequency of Tay-Sachs disease among Ashkenazic Jews unlikely by genetic drift alone. Am J Hum Genet (1978) 1.55
Population genetics of CAPN10 and GPR35: implications for the evolution of type 2 diabetes variants. Am J Hum Genet (2005) 1.55
Isolation, characterization, and mapping to chromosome 19 of the human apolipoprotein E gene. J Biol Chem (1985) 1.54
The Sox10(Dom) mouse: modeling the genetic variation of Waardenburg-Shah (WS4) syndrome. Genome Res (1999) 1.53
Help of the fire brigade in a case of a strangulated penis. Ann R Coll Surg Engl (2001) 1.51
A genetic linkage map of 17 markers on human chromosome 21. Genomics (1989) 1.50
Estimation of the marker gene frequency and linkage disequilibrium from conditional marker data. Am J Hum Genet (1984) 1.50
On the divergence of alleles in nested subsamples from finite populations. Genetics (1986) 1.49
Plasmodium falciparum antigenic diversity: evidence of clonal population structure. Proc Natl Acad Sci U S A (1997) 1.47
Diagnosis of genetic disorders at the DNA level. N Engl J Med (1989) 1.47
Synthesis, intracellular processing, and signal peptide of human apolipoprotein E. J Biol Chem (1984) 1.45
Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes. J Biol Chem (1986) 1.44
The winged helix/forkhead transcription factor Foxq1 regulates differentiation of hair in satin mice. Genesis (2001) 1.44
A genetic linkage map of 27 markers on human chromosome 21. Genomics (1991) 1.43
Gene trees, species trees and the segregation of ancestral alleles. Genetics (1992) 1.43
Mutation analysis of the RET receptor tyrosine kinase in Hirschsprung disease. Hum Mol Genet (1995) 1.43
Linkage analysis of the human HMG14 gene on chromosome 21 using a GT dinucleotide repeat as polymorphic marker. Genomics (1990) 1.43
Repression by ARP-1 sensitizes apolipoprotein AI gene responsiveness to RXR alpha and retinoic acid. Mol Cell Biol (1992) 1.43
Patterns of meiotic recombination on the long arm of human chromosome 21. Genome Res (2000) 1.40
Cutaneous malignant melanoma and familial dysplastic nevi: evidence for autosomal dominance and pleiotropy. Am J Hum Genet (1986) 1.39