Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria.

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Published in Proc Natl Acad Sci U S A on December 01, 1988

Authors

D S Peterson1, D Walliker, T E Wellems

Author Affiliations

1: Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892.

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