Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction.

PubWeight™: 62.23‹?› | Rank: Top 0.01% | All-Time Top 1000

🔗 View Article (PMC 1715443)

Published in Am J Hum Genet on March 01, 1989

Authors

J L Weber1, P E May

Author Affiliations

1: Marshfield Medical Research Foundation, WI 54449.

Articles citing this

(truncated to the top 100)

AFLP: a new technique for DNA fingerprinting. Nucleic Acids Res (1995) 45.26

Hypervariability of simple sequences as a general source for polymorphic DNA markers. Nucleic Acids Res (1989) 10.34

Mapping quantitative trait loci controlling milk production in dairy cattle by exploiting progeny testing. Genetics (1995) 9.26

Allele frequencies at microsatellite loci: the stepwise mutation model revisited. Genetics (1993) 8.60

Mapping by admixture linkage disequilibrium in human populations: limits and guidelines. Am J Hum Genet (1994) 7.16

DNA typing and genetic mapping with trimeric and tetrameric tandem repeats. Am J Hum Genet (1991) 6.20

Allele frequency estimation from data on relatives. Am J Hum Genet (1991) 5.62

Five polymorphic microsatellite VNTRs on the human X chromosome. Am J Hum Genet (1990) 5.38

A 3.9-centimorgan-resolution human single-nucleotide polymorphism linkage map and screening set. Am J Hum Genet (2003) 5.34

Dinucleotide repeat polymorphism at the D10S89 locus. Nucleic Acids Res (1990) 5.21

Slippage synthesis of simple sequence DNA. Nucleic Acids Res (1992) 5.18

The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet (2007) 5.02

Diversity Arrays Technology (DArT) for whole-genome profiling of barley. Proc Natl Acad Sci U S A (2004) 4.70

Instability of simple sequence DNA in Saccharomyces cerevisiae. Mol Cell Biol (1992) 4.46

Diversity arrays: a solid state technology for sequence information independent genotyping. Nucleic Acids Res (2001) 4.13

Molecular haplotyping of genetic markers 10 kb apart by allele-specific long-range PCR. Nucleic Acids Res (1996) 3.92

The complete sequence of 340 kb of DNA around the rice Adh1-adh2 region reveals interrupted colinearity with maize chromosome 4. Plant Cell (2000) 3.84

The polydeoxyadenylate tract of Alu repetitive elements is polymorphic in the human genome. Proc Natl Acad Sci U S A (1990) 3.72

A genetic linkage map for cattle. Genetics (1994) 3.64

Towards construction of a high resolution map of the mouse genome using PCR-analysed microsatellites. Nucleic Acids Res (1990) 3.59

Short, interspersed repetitive DNA sequences in prokaryotic genomes. J Bacteriol (1992) 3.33

SNP frequency, haplotype structure and linkage disequilibrium in elite maize inbred lines. BMC Genet (2002) 3.23

Saccharomyces cerevisiae RAD5-encoded DNA repair protein contains DNA helicase and zinc-binding sequence motifs and affects the stability of simple repetitive sequences in the genome. Mol Cell Biol (1992) 3.12

Population genetics of dinucleotide (dC-dA)n.(dG-dT)n polymorphisms in world populations. Am J Hum Genet (1995) 3.12

Natural selection and the frequency distributions of "silent" DNA polymorphism in Drosophila. Genetics (1997) 2.89

Genome screens using linkage disequilibrium tests: optimal marker characteristics and feasibility. Am J Hum Genet (1998) 2.86

Influence of aberrant observations on high-resolution linkage analysis outcomes. Am J Hum Genet (1991) 2.84

Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome. Am J Hum Genet (2003) 2.73

Localization of a gene for partial epilepsy to chromosome 10q. Nat Genet (1995) 2.72

Polygenic susceptibility in rheumatoid arthritis. Ann Rheum Dis (1991) 2.66

The abundance of various polymorphic microsatellite motifs differs between plants and vertebrates. Nucleic Acids Res (1993) 2.61

Polymers of random short oligonucleotides detect polymorphic loci in the human genome. Nucleic Acids Res (1989) 2.57

Physical mapping of human chromosomes by repetitive sequence fingerprinting. Proc Natl Acad Sci U S A (1990) 2.57

Polymorphic admixture typing in human ethnic populations. Am J Hum Genet (1994) 2.37

Copy number variants and common disorders: filling the gaps and exploring complexity in genome-wide association studies. PLoS Genet (2007) 2.32

Taq DNA polymerase slippage mutation rates measured by PCR and quasi-likelihood analysis: (CA/GT)n and (A/T)n microsatellites. Nucleic Acids Res (2003) 2.28

Molecular analysis of the Smith-Magenis syndrome: a possible contiguous-gene syndrome associated with del(17)(p11.2). Am J Hum Genet (1991) 2.26

Forward and reverse genetic approaches to behavior in the mouse. Science (1994) 2.20

Rapid detection of CA polymorphisms in cloned DNA: application to the 5' region of the dystrophin gene. Am J Hum Genet (1991) 2.17

Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma. J Natl Cancer Inst (2008) 2.17

Evaluation of 13 short tandem repeat loci for use in personal identification applications. Am J Hum Genet (1994) 2.15

Nonsyndromic cleft lip with or without cleft palate: evidence of linkage to BCL3 in 17 multigenerational families. Am J Hum Genet (1995) 2.12

Incorrect specification of marker allele frequencies: effects on linkage analysis. Am J Hum Genet (1993) 2.10

A mutation in the fibroblast growth factor 14 gene is associated with autosomal dominant cerebellar ataxia [corrected]. Am J Hum Genet (2002) 2.02

Molecular analyses of unrelated Charcot-Marie-Tooth (CMT) disease patients suggest a high frequency of the CMTIA duplication. Am J Hum Genet (1993) 1.97

Wild pedigrees: the way forward. Proc Biol Sci (2008) 1.95

Fragile X syndrome: diagnosis using highly polymorphic microsatellite markers. Am J Hum Genet (1991) 1.95

Carrier detection and prenatal diagnosis in Duchenne and Becker muscular dystrophy families, using dinucleotide repeat polymorphisms. Am J Hum Genet (1991) 1.93

Rapid detection of allele loss in colorectal tumours using microsatellites and fluorescent DNA technology. Br J Cancer (1993) 1.93

Evidence that a locus for familial high myopia maps to chromosome 18p. Am J Hum Genet (1998) 1.93

Fragile-X syndrome: unique genetics of the heritable unstable element. Am J Hum Genet (1992) 1.85

Polymorphic simple sequence repeat regions in chloroplast genomes: applications to the population genetics of pines. Proc Natl Acad Sci U S A (1995) 1.81

Retroviral and pseudogene insertion sites reveal the lineage of human salivary and pancreatic amylase genes from a single gene during primate evolution. Mol Cell Biol (1990) 1.79

An exclusion map for pre-eclampsia: assuming autosomal recessive inheritance. Am J Hum Genet (1992) 1.78

Identification of a highly polymorphic microsatellite VNTR within the argininosuccinate synthetase locus: exclusion of the dystonia gene on 9q32-34 as the cause of dopa-responsive dystonia in a large kindred. Am J Hum Genet (1991) 1.77

The efficiency of multilocus DNA fingerprint probes for individualization and establishment of family relationships, determined from extensive casework. Am J Hum Genet (1991) 1.76

An autosomal genetic linkage map of the sheep genome. Genetics (1995) 1.75

Fragile X syndrome: genetic localisation by linkage mapping of two microsatellite repeats FRAXAC1 and FRAXAC2 which immediately flank the fragile site. J Med Genet (1991) 1.71

EXT-mutation analysis and loss of heterozygosity in sporadic and hereditary osteochondromas and secondary chondrosarcomas. Am J Hum Genet (1999) 1.70

A second generation genetic map for rainbow trout (Oncorhynchus mykiss). BMC Genet (2008) 1.68

A microsatellite linkage map of the porcine genome. Genetics (1994) 1.64

Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription. J Clin Invest (1997) 1.63

Microsatellite variation in North American populations of Drosophila melanogaster. Nucleic Acids Res (1995) 1.63

Genetics of the Framingham Heart Study population. Adv Genet (2008) 1.62

Genetic analysis of traditional and evolved Basmati and non-Basmati rice varieties by using fluorescence-based ISSR-PCR and SSR markers. Proc Natl Acad Sci U S A (2002) 1.61

Friedreich ataxia in Italian families: genetic homogeneity and linkage disequilibrium with the marker loci D9S5 and D9S15. Am J Hum Genet (1990) 1.61

The determination of the sequences present in the shadow bands of a dinucleotide repeat PCR. Nucleic Acids Res (1993) 1.60

A simple sequence repeat polymorphism at the human growth hormone locus. Nucleic Acids Res (1991) 1.60

Genetic analysis of natural variations in the architecture of Arabidopsis thaliana vegetative leaves. Genetics (2002) 1.60

Simultaneous estimation of all the parameters of a stepwise mutation model. Genetics (1998) 1.60

Genetics and pulmonary medicine. 3. Genetic susceptibility to tuberculosis in human populations. Thorax (1998) 1.59

Construction of libraries enriched for sequence repeats and jumping clones, and hybridization selection for region-specific markers. Proc Natl Acad Sci U S A (1994) 1.57

Evidence for human meiotic recombination interference obtained through construction of a short tandem repeat-polymorphism linkage map of chromosome 19. Am J Hum Genet (1993) 1.57

Deletions spanning the neurofibromatosis 1 gene: identification and phenotype of five patients. Am J Hum Genet (1994) 1.56

Allelic variations in the human T cell receptor V beta 6.7 gene products. J Exp Med (1990) 1.55

Frequency of allele loss of DCC, p53, RBI, WT1, NF1, NM23 and APC/MCC in colorectal cancer assayed by fluorescent multiplex polymerase chain reaction. Br J Cancer (1994) 1.53

Mapping a cardiomyopathy locus to chromosome 3p22-p25. J Clin Invest (1996) 1.52

Toward fully automated genotyping: genotyping microsatellite markers by deconvolution. Am J Hum Genet (1995) 1.52

How is the Human Genome Project doing, and what have we learned so far? Proc Natl Acad Sci U S A (1995) 1.50

Disentangling the genetic determinants of human aging: biological age as an alternative to the use of survival measures. J Gerontol A Biol Sci Med Sci (2005) 1.50

X-linked dominant cone-rod degeneration: linkage mapping of a new locus for retinitis pigmentosa (RP 15) to Xp22.13-p22.11. Am J Hum Genet (1995) 1.49

Polymorphism and locus-specific effects on polymorphism at microsatellite loci in natural Drosophila melanogaster populations. Genetics (1997) 1.47

Tetranucleotide repeat polymorphism at the human coagulation factor XIII A subunit gene (F13A1). Nucleic Acids Res (1991) 1.46

Strong allelic association between the torsion dystonia gene (DYT1) andloci on chromosome 9q34 in Ashkenazi Jews. Am J Hum Genet (1992) 1.46

The genetic relationship between the Finns and the Finnish Saami (Lapps): analysis of nuclear DNA and mtDNA. Am J Hum Genet (1996) 1.46

A (CA)n dinucleotide repeat assay for evaluating loss of allelic heterozygosity in small and archival human brain tumor specimens. Am J Pathol (1992) 1.45

Mapping of a gene for autosomal dominant juvenile-onset open-angle glaucoma to chromosome Iq. Am J Hum Genet (1994) 1.44

A microsatellite linkage map of Barramundi, Lates calcarifer. Genetics (2006) 1.44

Phylogenetic assessment of length variation at a microsatellite locus. Proc Natl Acad Sci U S A (1997) 1.43

Microfabricated structures for integrated DNA analysis. Proc Natl Acad Sci U S A (1996) 1.41

Autosomal dominant retinitis pigmentosa with apparent incomplete penetrance: a clinical, electrophysiological, psychophysical, and molecular genetic study. Br J Ophthalmol (1993) 1.41

New insights into samango monkey speciation in South Africa. PLoS One (2015) 1.40

Partial isodisomy for maternal chromosome 7 and short stature in an individual with a mutation at the COL1A2 locus. Am J Hum Genet (1992) 1.40

Survey and analysis of microsatellites in the silkworm, Bombyx mori: frequency, distribution, mutations, marker potential and their conservation in heterologous species. Genetics (2004) 1.39

Dinucleotide repeat polymorphism at the D6S105 locus. Nucleic Acids Res (1991) 1.38

Microsatellite mutations and inferences about human demography. Genetics (2000) 1.37

Factors affecting fidelity of DNA synthesis during PCR amplification of d(C-A)n.d(G-T)n microsatellite repeats. Nucleic Acids Res (1996) 1.36

Microsatellite instability in sporadic colorectal cancer is not an independent prognostic factor. Br J Cancer (1999) 1.36

The 13q- syndrome: the molecular definition of a critical deletion region in band 13q32. Am J Hum Genet (1995) 1.36

A Gly1127Ser mutation in an EGF-like domain of the fibrillin-1 gene is a risk factor for ascending aortic aneurysm and dissection. Am J Hum Genet (1995) 1.35

Articles cited by this

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science (1988) 220.77

Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science (1985) 95.08

Screening lambdagt recombinant clones by hybridization to single plaques in situ. Science (1977) 83.82

Construction of a genetic linkage map in man using restriction fragment length polymorphisms. Am J Hum Genet (1980) 75.25

Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods Enzymol (1987) 58.68

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination. Proc Natl Acad Sci U S A (1983) 54.64

Hypervariable 'minisatellite' regions in human DNA. Nature (1985) 31.03

Variable number of tandem repeat (VNTR) markers for human gene mapping. Science (1987) 25.71

Human fetal G gamma- and A gamma-globin genes: complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes. Cell (1980) 14.88

Spontaneous mutation rates to new length alleles at tandem-repetitive hypervariable loci in human DNA. Nature (1988) 9.47

Simultaneous analysis of multiple polymorphic loci using amplified sequence polymorphisms (ASPs). Genomics (1988) 8.29

A novel repeated element with Z-DNA-forming potential is widely found in evolutionarily diverse eukaryotic genomes. Proc Natl Acad Sci U S A (1982) 8.15

A strategy to reveal high-frequency RFLPs along the human X chromosome. Am J Hum Genet (1984) 7.73

Simple sequences are ubiquitous repetitive components of eukaryotic genomes. Nucleic Acids Res (1984) 6.93

A member of a new repeated sequence family which is conserved throughout eucaryotic evolution is found between the human delta and beta globin genes. Nucleic Acids Res (1981) 6.70

The sequence (dC-dA)n X (dG-dT)n forms left-handed Z-DNA in negatively supercoiled plasmids. Proc Natl Acad Sci U S A (1983) 5.69

Enhanced gene expression by the poly(dT-dG).poly(dC-dA) sequence. Mol Cell Biol (1984) 4.44

Potential Z-DNA forming sequences are highly dispersed in the human genome. Nature (1982) 4.41

Repetitive proteins and genes of malaria. Annu Rev Microbiol (1987) 4.30

Sequence of the human somatostatin I gene. Science (1984) 3.48

Characterization of genomic poly(dT-dG).poly(dC-dA) sequences: structure, organization, and conformation. Mol Cell Biol (1984) 3.42

Non-Alu family interspersed repeats in human DNA and their transcriptional activity. Nucleic Acids Res (1984) 3.30

(dC-dA)n.(dG-dT)n sequences have evolutionarily conserved chromosomal locations in Drosophila with implications for roles in chromosome structure and function. EMBO J (1987) 3.28

Identification of more than 500 RFLPs by screening random genomic clones. Am J Hum Genet (1988) 3.01

The ubiquitous potential Z-forming sequence of eucaryotes, (dT-dG)n . (dC-dA)n, is not detectable in the genomes of eubacteria, archaebacteria, or mitochondria. Mol Cell Biol (1986) 3.00

Structure of the major block of alphoid satellite DNA on the human Y chromosome. J Mol Biol (1987) 2.95

Molecular biology of malaria parasites. Exp Parasitol (1988) 2.87

The human apolipoprotein C-II gene sequence contains a novel chromosome 19-specific minisatellite in its third intron. J Biol Chem (1987) 2.85

Isolation of polymorphic DNA fragments from human chromosome 4. Nucleic Acids Res (1987) 2.83

Chromosome-specific alpha satellite DNA from human chromosome 1: hierarchical structure and genomic organization of a polymorphic domain spanning several hundred kilobase pairs of centromeric DNA. Genomics (1987) 2.77

Identification of 28 DNA fragments that detect RFLPs in 13 distinct physical regions of the short arm of chromosome 5. Nucleic Acids Res (1987) 2.72

Locations and contexts of sequences that hybridize to poly(dG-dT).(dC-dA) in mammalian ribosomal DNAs and two X-linked genes. Nucleic Acids Res (1988) 2.64

Normal and abnormal color-vision genes. Am J Hum Genet (1988) 2.61

Chromatin structure of the potential Z-forming sequence (dT-dG)n X (dC-dA)n. Evidence for an "alternating-B" conformation. J Mol Biol (1985) 2.58

Primary structure of a Plasmodium falciparum malaria antigen located at the merozoite surface and within the parasitophorous vacuole. J Biol Chem (1988) 2.43

Molecular analyses of in vivo hprt mutations in human T-lymphocytes. I. Studies of low frequency 'spontaneous' mutants by Southern blots. Mutagenesis (1987) 2.33

Articles by these authors

Dinucleotide repeat polymorphism at the D10S89 locus. Nucleic Acids Res (1990) 5.21

Dinucleotide repeat polymorphisms at the D17S250 and D17S261 loci. Nucleic Acids Res (1990) 2.62

Mapping of human chromosome 5 microsatellite DNA polymorphisms. Genomics (1991) 1.74

Dinucleotide repeat polymorphism at the D6S105 locus. Nucleic Acids Res (1991) 1.38

Dinucleotide repeat polymorphism at the D12S43 locus. Nucleic Acids Res (1990) 1.33

Dinucleotide repeat polymorphisms at the DXS453, DXS454 and DXS458 loci. Nucleic Acids Res (1990) 1.32

Dinucleotide repeat polymorphisms at the D16S260, D16S261, D16S265, D16S266, and D16S267 loci. Nucleic Acids Res (1990) 1.22

Linkage mapping of the highly informative DNA marker D21S156 to human chromosome 21 using a polymorphic GT dinucleotide repeat. Genomics (1990) 1.08

Dinucleotide repeat polymorphisms at the D11S419 and CD3D loci. Nucleic Acids Res (1990) 1.04

Dinucleotide repeat polymorphism at the D6S87 locus. Nucleic Acids Res (1990) 0.94

Dinucleotide repeat polymorphisms at the D8S85, D8S87, and D8S88 loci. Nucleic Acids Res (1990) 0.93

Dinucleotide repeat polymorphism at the D4S174 locus. Nucleic Acids Res (1990) 0.91

Dinucleotide repeat polymorphism at the D19S75 locus. Nucleic Acids Res (1990) 0.89

Dinucleotide repeat polymorphism at the D1S102 locus. Nucleic Acids Res (1990) 0.88

Dinucleotide repeat polymorphism at the D19S49 locus. Nucleic Acids Res (1990) 0.87

Dinucleotide repeat polymorphisms at the D7S435 and D7S440 loci. Nucleic Acids Res (1990) 0.87

Dinucleotide repeat polymorphism at the D15S87 locus. Nucleic Acids Res (1990) 0.87

Dinucleotide repeat polymorphism at the D9S43 locus. Nucleic Acids Res (1990) 0.86

Merozoite surface protein sequence from the Camp strain of the human malaria parasite Plasmodium falciparum. Nucleic Acids Res (1988) 0.85

Dinucleotide repeat polymorphism at the D4S171 locus. Nucleic Acids Res (1990) 0.85

Dinucleotide repeat polymorphism at the D1S104 locus. Nucleic Acids Res (1990) 0.82

The role of Chlamydia trachomatis in urethritis and urethral symptoms in women. Int J STD AIDS (1995) 0.80

Dinucleotide repeat polymorphisms at the D5S107, D5S108, D5S111, D5S117 and D5S118 loci. Nucleic Acids Res (1990) 0.80

Dinucleotide repeat polymorphism at the D13S71 locus. Nucleic Acids Res (1990) 0.80

Dinucleotide repeat polymorphism at the CRP locus. Nucleic Acids Res (1990) 0.79

Dinucleotide repeat polymorphism at the D18S34 locus. Nucleic Acids Res (1990) 0.79

Dinucleotide repeat polymorphism at the D2S72 locus. Nucleic Acids Res (1990) 0.78

Dinucleotide repeat polymorphism at the D20S27 locus. Nucleic Acids Res (1990) 0.78

Dinucleotide repeat polymorphism at the D22S156 locus. Nucleic Acids Res (1990) 0.78

Dinucleotide repeat polymorphism at the D1S103 locus. Nucleic Acids Res (1990) 0.78

Effect of oral nutritional supplementation on wound healing in diabetic foot ulcers: a prospective randomized controlled trial. Diabet Med (2014) 0.77

Dinucleotide repeat polymorphism at the PENK locus. Nucleic Acids Res (1990) 0.77

Dinucleotide repeat polymorphism at the D18S34 locus. Nucleic Acids Res (1990) 0.77

Dinucleotide repeat polymorphism at the D14S34 locus. Nucleic Acids Res (1990) 0.75

Dinucleotide repeat polymorphism at the D3S240 locus. Nucleic Acids Res (1990) 0.75

Dinucleotide repeat polymorphism at the D2S71 locus. Nucleic Acids Res (1990) 0.75

Dinucleotide repeat polymorphism at the D18S35 locus. Nucleic Acids Res (1990) 0.75

Dinucleotide repeat polymorphism at the D3S196 locus. Nucleic Acids Res (1990) 0.75

Dinucleotide repeat polymorphism at the D19S76 locus. Nucleic Acids Res (1990) 0.75

Ventricular fibrillation during anesthesia. Vet Med Small Anim Clin (1981) 0.75