Therapeutic potential of heat shock protein induction for muscular dystrophy and other muscle wasting conditions.

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Published in Philos Trans R Soc Lond B Biol Sci on January 19, 2018

Authors

Savant S Thakur1, Kristy Swiderski1, James G Ryall1, Gordon S Lynch2

Author Affiliations

1: Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Parkville, Victoria, Australia.
2: Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Parkville, Victoria, Australia gsl@unimelb.edu.au.

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Inflammatory processes in muscle injury and repair. Am J Physiol Regul Integr Comp Physiol (2005) 4.47

Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells. J Biol Chem (1984) 4.20

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Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy. J Clin Invest (2007) 2.99

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Hsp72 preserves muscle function and slows progression of severe muscular dystrophy. Nature (2012) 2.04

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AlphaB-crystallin immunolocalization yields new insights into inclusion body myositis. Neurology (2000) 1.77

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Overexpression of HSP70 in mouse skeletal muscle protects against muscle damage and age-related muscle dysfunction. FASEB J (2003) 1.56

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An adult tissue-specific stem cell in its niche: a gene profiling analysis of in vivo quiescent and activated muscle satellite cells. Stem Cell Res (2009) 1.46

Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle. J Clin Invest (2011) 1.42

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Effect of lifelong overexpression of HSP70 in skeletal muscle on age-related oxidative stress and adaptation after nondamaging contractile activity. FASEB J (2006) 1.32

Regenerated mdx mouse skeletal muscle shows differential mRNA expression. J Appl Physiol (1985) (2002) 1.26

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In vivo delivery of heat shock protein 70 accelerates wound healing by up-regulating macrophage-mediated phagocytosis. Wound Repair Regen (2006) 1.13

Resting calcium concentrations in isolated skeletal muscle fibres of dystrophic mice. J Physiol (1990) 1.12

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Activation of JNK1 contributes to dystrophic muscle pathogenesis. Curr Biol (2001) 1.11

Expression of stress proteins and mitochondrial chaperonins in chronically stimulated skeletal muscle. Biochem J (1995) 1.08

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Disruption of zebrafish somite development by pharmacologic inhibition of Hsp90. Dev Biol (1999) 1.00

Stress proteins: the exercise response. Can J Appl Physiol (1995) 0.99

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Response and function of skeletal muscle heat shock protein 70. Front Biosci (2006) 0.95

Temporospatial expression of the small HSP/alpha B-crystallin in cardiac and skeletal muscle during mouse development. Dev Dyn (1997) 0.94

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The role of heat shock proteins in the heart. J Mol Cell Cardiol (1995) 0.93

The murine alpha B-crystallin/small heat shock protein enhancer: identification of alpha BE-1, alpha BE-2, alpha BE-3, and MRF control elements. Mol Cell Biol (1993) 0.93

Stress and stem cells. Wiley Interdiscip Rev Dev Biol (2012) 0.93

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Regulation of the levels of small heat-shock proteins during differentiation of C2C12 cells. Exp Cell Res (2001) 0.86

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Skeletal muscle heat shock protein 70: diverse functions and therapeutic potential for wasting disorders. Front Physiol (2013) 0.84

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Profiling of age-related changes in the tibialis anterior muscle proteome of the mdx mouse model of dystrophinopathy. J Biomed Biotechnol (2012) 0.82

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Progesterone receptor deficient in chromatin binding has an altered cellular state. J Biol Chem (2004) 0.81

Skeletal muscles of aged male mice fail to adapt following contractile activity. Biochem Soc Trans (2003) 0.81

The loss of muscle mass and sarcopenia: non hormonal intervention. Exp Gerontol (2011) 0.81

Heat shock protein families 70 and 90 in Duchenne muscular dystrophy and inflammatory myopathy: balancing muscle protection and destruction. Neuromuscul Disord (2011) 0.81

Overexpression of inducible 70-kDa heat shock protein in mouse improves structural and functional recovery of skeletal muscles from atrophy. Pflugers Arch (2012) 0.81

Pathological changes in levels of three small stress proteins, alphaB crystallin, HSP 27 and p20, in the hindlimb muscles of dy mouse. Biochim Biophys Acta (1998) 0.81

Expression of heat-shock/stress proteins in Duchenne muscular dystrophy. Muscle Nerve (1995) 0.81

Genetic evidence in the mouse solidifies the calcium hypothesis of myofiber death in muscular dystrophy. Cell Death Differ (2015) 0.81

Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D. Hum Mol Genet (2015) 0.79

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Pharmacological inhibition of HSP90 activity negatively modulates myogenic differentiation and cell survival in C2C12 cells. Mol Cell Biochem (2011) 0.78

Endogenous expression and developmental changes of HSP72 in rat skeletal muscles. J Appl Physiol (1985) (2003) 0.78

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Expression of 65-kd heat shock proteins in the inflammatory myopathies. Ann Neurol (1992) 0.77

Emerging drugs for treating skeletal muscle injury and promoting muscle repair. Expert Opin Emerg Drugs (2011) 0.77

BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle. Am J Pathol (2016) 0.76

Small heat shock protein HSPB1 regulates growth of embryonic zebrafish craniofacial muscles. Exp Cell Res (2013) 0.76