Published in Zhongguo Yao Li Xue Bao on July 01, 1986
The sequence of the human genome. Science (2001) 101.55
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest (1999) 8.38
Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. Science (1999) 7.86
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication. Nature (2001) 7.31
The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds. Nat Genet (1996) 6.43
Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions. Science (2000) 5.62
Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1). J Exp Med (2001) 4.71
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size. Nat Nanotechnol (2011) 4.22
Smoking cessation with and without assistance: a population-based analysis. Am J Prev Med (2000) 3.92
The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins. Nat Genet (1996) 3.35
Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists. J Med Chem (2000) 3.34
Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues. J Med Chem (2001) 3.24
Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Free Radic Biol Med (2005) 3.13
Hepatitis B genotypes and the response to interferon therapy. J Hepatol (2000) 2.97
Nanostructured high-strength molybdenum alloys with unprecedented tensile ductility. Nat Mater (2013) 2.90
Gate-tuning of graphene plasmons revealed by infrared nano-imaging. Nature (2012) 2.75
BRCA2 germline mutations in male breast cancer cases and breast cancer families. Nat Genet (1996) 2.75
Gallbladder muscle dysfunction in patients with chronic acalculous disease. Gastroenterology (2001) 2.73
Do rehabilitative nursing homes improve the outcomes of care? J Am Geriatr Soc (1996) 2.63
Molecular characterization and transcriptional analysis of type 8 capsule genes in Staphylococcus aureus. J Bacteriol (1997) 2.58
Clinical manifestations and diagnosis of acute pyrethroid poisoning. Arch Toxicol (1989) 2.50
Role of nonimmune IgG bound to PfEMP1 in placental malaria. Science (2001) 2.50
The skeletal muscle calcium release channel: coupled O2 sensor and NO signaling functions. Cell (2000) 2.41
Site-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemia. EMBO J (1990) 2.38
Evidence of increased oxidative damage in subjects with mild cognitive impairment. Neurology (2005) 2.33
The common SCN5A mutation R1193Q causes LQTS-type electrophysiological alterations of the cardiac sodium channel. J Med Genet (2004) 2.33
Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells. J Leukoc Biol (2000) 2.32
Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1. EMBO J (2001) 2.32
Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3-E1 osteoblasts. J Biol Chem (2001) 2.27
Enhancer-binding activity of the tal-1 oncoprotein in association with the E47/E12 helix-loop-helix proteins. Mol Cell Biol (1991) 2.25
Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection. Immunity (1996) 2.24
Induction of alpha-synuclein aggregation by intracellular nitrative insult. J Neurosci (2001) 2.16
Small, clonally variant antigens expressed on the surface of the Plasmodium falciparum-infected erythrocyte are encoded by the rif gene family and are the target of human immune responses. J Exp Med (1999) 2.11
Predictors of smoking cessation in U.S. adolescents. Am J Prev Med (1999) 2.09
IMPACT trial results should not change current standard of care of 100 days for cytomegalovirus prophylaxis. Am J Transplant (2010) 2.05
Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation. EMBO J (1997) 2.02
Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies. J Biol Chem (2000) 2.02
Further characterization of endometrial integrins during the menstrual cycle and in pregnancy. Fertil Steril (1994) 1.99
Smoking, air pollution, and the high rates of lung cancer in Shenyang, China. J Natl Cancer Inst (1989) 1.99
Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow. J Biomech Eng (2000) 1.96
Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects. Proc Natl Acad Sci U S A (1999) 1.95
Indoor radon and lung cancer in China. J Natl Cancer Inst (1990) 1.95
Pseudomonas aeruginosa ExoS and ExoT. Rev Physiol Biochem Pharmacol (2004) 1.91
KCNE1 mutations cause jervell and Lange-Nielsen syndrome. Nat Genet (1997) 1.90
Reverse transcriptase in a clinical strain of Escherichia coli: production of branched RNA-linked msDNA. Science (1989) 1.89
A phospholipid acts as a chaperone in assembly of a membrane transport protein. J Biol Chem (1996) 1.89
Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2. J Biol Chem (1996) 1.87
Effects of pyrethroid insecticides on subjects engaged in packaging pyrethroids. Br J Ind Med (1988) 1.87
Present-day crustal deformation in China constrained by global positioning system measurements. Science (2001) 1.87
Rainforest aerosols as biogenic nuclei of clouds and precipitation in the Amazon. Science (2010) 1.86
Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts. J Cell Biol (1997) 1.78
Local anesthesia for functional endoscopic sinus surgery employing small volumes of epinephrine-containing solutions of lidocaine produces profound hypotension. Acta Anaesthesiol Scand (2005) 1.77
Cell anchorage permits efficient signal transduction between ras and its downstream kinases. J Biol Chem (1997) 1.75
Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes. J Biol Chem (1995) 1.75
Low incidence of BRCA2 mutations in breast carcinoma and other cancers. Nat Genet (1996) 1.74
Fresh isolates from children with severe Plasmodium falciparum malaria bind to multiple receptors. Infect Immun (2001) 1.72
Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules. Proc Natl Acad Sci U S A (1998) 1.71
IL-13 stimulates vascular endothelial cell growth factor and protects against hyperoxic acute lung injury. J Clin Invest (2000) 1.66
ACAPs are arf6 GTPase-activating proteins that function in the cell periphery. J Cell Biol (2000) 1.66
GFI1B mutation causes a bleeding disorder with abnormal platelet function. J Thromb Haemost (2013) 1.66
High-resolution soft X-ray beamline ADRESS at the Swiss Light Source for resonant inelastic X-ray scattering and angle-resolved photoelectron spectroscopies. J Synchrotron Radiat (2010) 1.66
High-dose/activation-associated tolerance: a mechanism for allograft tolerance. Transplantation (1997) 1.65
Synaptonemal complex antigen location and conservation. J Cell Biol (1987) 1.65
Intramural mechanics of the human tongue in association with physiological deformations. J Biomech (1999) 1.63
Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection. Methods Enzymol (1994) 1.62
Superficial buffer barrier function of smooth muscle sarcoplasmic reticulum. Trends Pharmacol Sci (1995) 1.62
A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator. J Biol Chem (2000) 1.62
Role of CD4+ T cells in pathogenesis associated with Leishmania amazonensis infection. J Immunol (1997) 1.62
A short course of methylprednisolone immunosuppression inhibits both rejection and spontaneous acceptance of rat liver allografts. Transplantation (2001) 1.61
PIK3CA exon 20 mutations as a potential biomarker for resistance to anti-EGFR monoclonal antibodies in KRAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis. Ann Oncol (2011) 1.61
Generation and characterization of a cold-adapted influenza A H9N2 reassortant as a live pandemic influenza virus vaccine candidate. Vaccine (2003) 1.61
Prevalence of naturally occurring surface gene variants of hepatitis B virus in nonimmunized surface antigen-negative Chinese carriers. Hepatology (2001) 1.61
The Bacillus subtilis DinR binding site: redefinition of the consensus sequence. J Bacteriol (1998) 1.61
Neural cell type-specific expression of QKI proteins is altered in quakingviable mutant mice. J Neurosci (1996) 1.60
Histopathological, cytogenetic, and molecular characterization of renal cortical tumors. Cancer Res (1991) 1.59
Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway. Mol Cell Biol (1998) 1.59
A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP-2 alpha subunit. Implications for the endocytic pathway. J Biol Chem (1996) 1.58
Endometrial progesterone receptors and markers of uterine receptivity in the window of implantation. Fertil Steril (1996) 1.58
Type 1 and type 2 cytokine regulation of macrophage endocytosis: differential activation by IL-4/IL-13 as opposed to IFN-gamma or IL-10. J Immunol (1999) 1.58
Sensitivity analyses including and excluding the HWE-violating studies are required for meta-analyses of genetic association studies. Breast Cancer Res Treat (2009) 1.56
New mutations in the KVLQT1 potassium channel that cause long-QT syndrome. Circulation (1998) 1.53
Identification of novel CHD1-associated collaborative alterations of genomic structure and functional assessment of CHD1 in prostate cancer. Oncogene (2011) 1.50
Conformational changes and coactivator recruitment by novel ligands for estrogen receptor-alpha and estrogen receptor-beta: correlations with biological character and distinct differences among SRC coactivator family members. Endocrinology (2000) 1.50
Turbo spin-echo diffusion-weighted MR of ischemic stroke. AJNR Am J Neuroradiol (1998) 1.50
Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies. Am J Pathol (2000) 1.50
Proteolytic degradation of tyrosine nitrated proteins. Arch Biochem Biophys (2000) 1.49
Revision surgery for lumbar disc herniation. An analysis of 45 patients. Int Orthop (1995) 1.48
The incremental direct costs associated with behavioral symptoms in AD. Neurology (2002) 1.48
Metoprolol and mephenytoin oxidation polymorphisms in Far Eastern Oriental subjects: Japanese versus mainland Chinese. Clin Pharmacol Ther (1989) 1.48
Hepatic radioembolization with Yttrium-90 glass microspheres for treatment of primary liver cancer. Chin Med J (Engl) (1999) 1.48
Abnormalities of gallbladder muscle associated with acute inflammation in guinea pigs. Am J Physiol Gastrointest Liver Physiol (2001) 1.48
Real-time measurements of DNA hybridization on microparticles with fluorescence resonance energy transfer. Anal Biochem (1999) 1.47
The cell type-specific expression of the murine IL-13 gene is regulated by GATA-3. J Immunol (2001) 1.47
The dystrobrevin-binding protein 1 gene: features and networks. Mol Psychiatry (2008) 1.47
Treatment with low-dose aspirin increased the level LIF and integrin β3 expression in mice during the implantation window. Placenta (2010) 1.46
The optimal outcomes of post-hospital care under medicare. Health Serv Res (2000) 1.46
The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group. Leukemia (2009) 1.45
Promising thermoelectric properties of commercial PEDOT:PSS materials and their bi2Te3 powder composites. ACS Appl Mater Interfaces (2010) 1.45