Effect of 5-Day Nitrofurantoin vs Single-Dose Fosfomycin on Clinical Resolution of Uncomplicated Lower Urinary Tract Infection in Women: A Randomized Clinical Trial.

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🔗 View Article (PMID 29710295)

Published in JAMA on May 16, 2018

Authors

Angela Huttner1,2, Anna Kowalczyk3, Adi Turjeman4, Tanya Babich4, Caroline Brossier1, Noa Eliakim-Raz4,5, Katarzyna Kosiek6, Begoña Martinez de Tejada7, Xavier Roux8, Shachaf Shiber9, Ursula Theuretzbacher10, Elodie von Dach2,11, Dafna Yahav4,12, Leonard Leibovici4,5, Maciek Godycki-Cwirko3,6, Johan W Mouton13, Stephan Harbarth1,2

Author Affiliations

1: Infection Control Program, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.
2: Division of Infectious Diseases, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.
3: Centre for Family and Community Medicine, Medical University of Lodz, Lodz, Poland.
4: Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
5: Department of Internal Medicine E, Rabin Medical Center, Beilinson Campus, Peta-Tiqva, Israel.
6: Faculty of Health Sciences, Division of Public Health, Medical University of Lodz, Lodz, Poland.
7: Obstetrics Division, Department of Obstetrics and Gynecology, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.
8: Department of Internal Medicine, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.
9: Department of Emergency Medicine, Rabin Medical Center, Beilinson Campus, Peta-Tiqva, Israel.
10: Center for Anti-Infective Agents, Vienna, Austria.
11: Clinical Trials Unit, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.
12: Infectious Diseases Unit, Rabin Medical Center, Beilinson Hospital, Petah-Tiqva, Israel.
13: Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, the Netherlands.

Associated clinical trials:

Study Comparing Nitrofurantoin to Fosfomycin for Acute Urinary Tract Infection in Women (AIDA-WP2) | NCT01966653