Published in J Biol Chem on January 25, 1985
Receptor-mediated endocytosis of epidermal growth factor by rat hepatocytes: receptor pathway. J Cell Biol (1986) 1.94
Insulin-activated tyrosine phosphorylation of a 15-kilodalton protein in intact 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (1987) 1.65
Vaccinia virus growth factor stimulates tyrosine protein kinase activity of A431 cell epidermal growth factor receptors. Mol Cell Biol (1986) 1.33
Implications of epidermal growth factor (EGF) induced egf receptor aggregation. Biophys J (1992) 1.25
Epidermal growth factor receptor fate is controlled by Hrs tyrosine phosphorylation sites that regulate Hrs degradation. Mol Cell Biol (2006) 1.20
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A431 cell variants lacking the blood group A antigen display increased high affinity epidermal growth factor-receptor number, protein-tyrosine kinase activity, and receptor turnover. J Cell Biol (1988) 1.01
N-linked glycosylation is essential for the stability but not the signaling function of the interleukin-6 signal transducer glycoprotein 130. J Biol Chem (2009) 0.98
Proviral insertional activation of c-erbB: differential processing of the protein products arising from two alternate transcripts. Mol Cell Biol (1988) 0.96
Heterogeneity of epidermal growth factor binding kinetics on individual cells. Biophys J (1997) 0.90
The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine mode. Mol Biol Cell (2005) 0.88
N-glycans modulate the activation of gp130 in mouse embryonic neural precursor cells. Biochem Biophys Res Commun (2009) 0.86
Analysis of the role of N-glycosylation in cell-surface expression and binding properties of angiotensin II type-2 receptor of rat pheochromocytoma cells. Biochem J (1996) 0.84
Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface. J Biol Chem (2015) 0.83
Retention of epidermal growth factor receptors in the endoplasmic reticulum of adenovirus-infected cells. Biochem J (1992) 0.76
Proteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-Glycosylation. PLoS Biol (2017) 0.75
The oligosaccharide component of alpha 1-adrenergic receptors from BC3H1 and DDT1 muscle cells. Studies with glycosidases and photoaffinity labelling of intact cells. Biochem J (1988) 0.75
Spinach ribulose diphosphate carboxylase. I. Purification and properties of the enzyme. Biochemistry (1966) 5.87
Transcriptional regulation of gene expression during adipocyte differentiation. Annu Rev Biochem (1995) 5.75
Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes. Genes Dev (1989) 5.59
Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes. J Biol Chem (1980) 5.06
Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors. Science (2000) 4.62
Leptin regulates proinflammatory immune responses. FASEB J (1998) 4.31
CCAAT/enhancer binding protein gene promoter: binding of nuclear factors during differentiation of 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1991) 3.98
Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. Proc Natl Acad Sci U S A (1997) 3.79
Lipoprotein lipase suppression in 3T3-L1 cells by an endotoxin-induced mediator from exudate cells. Proc Natl Acad Sci U S A (1982) 3.69
CCAAT/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program. Proc Natl Acad Sci U S A (1994) 3.66
Induction of lipogenesis during differentiation in a "preadipocyte" cell line. J Biol Chem (1976) 3.62
Evidence for the involvement of vicinal sulfhydryl groups in insulin-activated hexose transport by 3T3-L1 adipocytes. J Biol Chem (1985) 3.51
Antisense CCAAT/enhancer-binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes. Genes Dev (1992) 3.41
A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: transcriptional activator lacking antimitotic activity. Proc Natl Acad Sci U S A (1993) 3.33
Activation and centromeric localization of CCAAT/enhancer-binding proteins during the mitotic clonal expansion of adipocyte differentiation. Genes Dev (1999) 3.19
Regulation of adipocyte development. Annu Rev Nutr (1994) 3.09
Mouse insulin-responsive glucose transporter gene: characterization of the gene and trans-activation by the CCAAT/enhancer binding protein. Proc Natl Acad Sci U S A (1990) 3.05
Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein. Proc Natl Acad Sci U S A (1984) 2.98
The enzymatic carboxylation of phosphoenolpyruvate. II. Purification and properties of liver mitochondrial phosphoenolpyruvate carboxykinase. J Biol Chem (1966) 2.89
Evidence for an increase in transcription of specific mRNAs during differentiation of 3T3-L1 preadipocytes. J Biol Chem (1985) 2.75
Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase. J Biol Chem (1988) 2.73
Sequence, tissue distribution, and differential expression of mRNA for a putative insulin-responsive glucose transporter in mouse 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (1989) 2.69
Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase. J Biol Chem (1989) 2.47
The biotin-dependent enzymes. Adv Enzymol Relat Areas Mol Biol (1971) 2.45
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Regulating adipogenesis. J Biol Chem (1997) 2.40
The enzymatic carboxylation of phosphoenolpyruvate. I. Purification and properties of phosphoenolpyruvate carboxylase. J Biol Chem (1966) 2.20
Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (1995) 2.17
Synthesis, turnover, and down-regulation of epidermal growth factor receptors in human A431 epidermoid carcinoma cells and skin fibroblasts. J Biol Chem (1982) 2.10
Inhibition of ribulose diphosphate carboxylase by cyanide. Inactive ternary complex of enzyme, ribulose diphosphate, and cyanide. J Biol Chem (1969) 2.04
On the mechanism of ligand-induced down-regulation of insulin receptor level in the liver cell. J Biol Chem (1981) 2.03
Nonidentical subunits of ribulose diphosphate carboxylase. Biochem Biophys Res Commun (1967) 2.02
Alterations in insulin binding accompanying differentiation of 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1977) 2.01
Acetyl coenzyme A carboxylase system of Escherichia coli. Purification and properties of the biotin carboxylase, carboxyltransferase, and carboxyl carrier protein components. J Biol Chem (1974) 1.99
Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion. J Biol Chem (1999) 1.94
The interaction of metal ions with ribulose 1,5-diphosphate carboxylase from spinach. J Biol Chem (1970) 1.94
Acetyl coenzyme A carboxylase. Curr Top Cell Regul (1974) 1.94
Transcriptional activation of the mouse obese (ob) gene by CCAAT/enhancer binding protein alpha. Proc Natl Acad Sci U S A (1996) 1.92
Repressive effect of Sp1 on the C/EBPalpha gene promoter: role in adipocyte differentiation. Mol Cell Biol (1999) 1.90
Effect of tunicamycin on the secretion of serum proteins by primary cultures of rat and chick hepatocytes. Studies on transferrin, very low density lipoprotein, and serum albumin. J Biol Chem (1978) 1.88
Adipocyte differentiation and leptin expression. Annu Rev Cell Dev Biol (1997) 1.86
Selective changes in microsomal enzymes of triacylglycerol phosphatidylcholine, and phosphatidylethanolamine biosynthesis during differentiation of 3T3-L1 preadipocytes. J Biol Chem (1978) 1.86
Role of C/EBP homologous protein (CHOP-10) in the programmed activation of CCAAT/enhancer-binding protein-beta during adipogenesis. Proc Natl Acad Sci U S A (2000) 1.85
Insulin receptor synthesis and turnover in differentiating 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1980) 1.82
Promoter-cDNA-directed heterologous protein expression in Xenopus laevis oocytes. Proc Natl Acad Sci U S A (1992) 1.79
Molecular characteristics of liver acetyl CoA carboxylase. Proc Natl Acad Sci U S A (1966) 1.78
Insulin regulates transcription of the CCAAT/enhancer binding protein (C/EBP) alpha, beta, and delta genes in fully-differentiated 3T3-L1 adipocytes. J Biol Chem (1995) 1.77
Liver acetyl coenzyme A carboxylase. I. Isolation and cat- alytic properties. J Biol Chem (1968) 1.74
Cell-free transcription directed by the 422 adipose P2 gene promoter: activation by the CCAAT/enhancer binding protein. Proc Natl Acad Sci U S A (1991) 1.72
Selective inhibition of synthesis of enzymes for de novo fatty acid biosynthesis by an endotoxin-induced mediator from exudate cells. Proc Natl Acad Sci U S A (1983) 1.68
Tissue specific expression of p422 protein, a putative lipid carrier, in mouse adipocytes. Biochem Biophys Res Commun (1985) 1.66
Insulin-activated tyrosine phosphorylation of a 15-kilodalton protein in intact 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (1987) 1.65
A mild procedure for the rapid release of cytoplasmic enzymes from cultured animal cells. Anal Biochem (1979) 1.63
Role of glycosylation in the processing of newly translated insulin proreceptor in 3T3-L1 adipocytes. J Biol Chem (1984) 1.62
Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes. Proc Natl Acad Sci U S A (1997) 1.55
Mitotic clonal expansion during preadipocyte differentiation: calpain-mediated turnover of p27. J Biol Chem (2000) 1.55
Substrate phosphorylation catalyzed by the insulin receptor tyrosine kinase. Kinetic correlation to autophosphorylation of specific sites in the beta subunit. J Biol Chem (1989) 1.49
Glucocorticoids reciprocally regulate expression of the CCAAT/enhancer-binding protein alpha and delta genes in 3T3-L1 adipocytes and white adipose tissue. J Biol Chem (1994) 1.46
Liver acetyl CoA carboxylase and fatty acid synthetase: relative activities in the normal state and in hereditary obesity. Biochem Biophys Res Commun (1967) 1.45
Role of pyruvate carboxylase in fatty acid synthesis: alterations during preadipocyte differentiation. Biochem Biophys Res Commun (1977) 1.44
Post-translational changes in tertiary and quaternary structure of the insulin proreceptor. Correlation with acquisition of function. J Biol Chem (1988) 1.44
Expression of the differentiation-induced gene for fatty acid-binding protein is activated by glucocorticoid and cAMP. Proc Natl Acad Sci U S A (1988) 1.40
Mechanism of regulation of the 422(aP2) gene by cAMP during preadipocyte differentiation. Proc Natl Acad Sci U S A (1989) 1.36
3-Hydroxy-3-methylgutaryl-CoA synthase. Participation of acetyl-S-enzyme and enzyme-S-hydroxymethylgutaryl-SCoA intermediates in the reaction. J Biol Chem (1977) 1.35
Transcriptional repression of the mouse insulin-responsive glucose transporter (GLUT4) gene by cAMP. Proc Natl Acad Sci U S A (1991) 1.33
The enzymatic carboxylation of phosphoenolpyruvate. 3. Investigation of the kinetics and mechanism of the mitochondrial phosphoenolpyruvate carboxykinase-catalyzed reaction. J Biol Chem (1966) 1.30
Stringent control of fatty acid synthesis in Escherichia coli. Possible regulation of acetyl coenzyme A carboxylase by ppGpp. J Biol Chem (1973) 1.29
Role of calpain in adipocyte differentiation. Proc Natl Acad Sci U S A (1999) 1.26
Activation of glucose uptake by insulin and insulin-like growth factor I in Xenopus oocytes. Proc Natl Acad Sci U S A (1989) 1.26
Molecular and catalytic properties of mitochondrial (ketogenic) 3-hydroxy-3-methylglutaryl coenzyme A synthase of liver. J Biol Chem (1975) 1.24
Rapid, reversible internalization of cell surface insulin receptors. Correlation with insulin-induced down-regulation. J Biol Chem (1983) 1.23
Changes in mammary-gland acetyl-coenzyme A carboxylase associated with lactogenic differentiation. Biochem J (1977) 1.23
Insulin stimulates fluid-phase endocytosis and exocytosis in 3T3-L1 adipocytes. J Biol Chem (1986) 1.22
Tumor necrosis factor alpha promotes nuclear localization of cytokine-inducible CCAAT/enhancer binding protein isoforms in hepatocytes. J Biol Chem (1996) 1.22
CCAAT/enhancer binding protein alpha (C/EBP alpha) undifferentiated protein: a developmentally regulated nuclear protein that binds to the C/EBP alpha gene promoter. Proc Natl Acad Sci U S A (1993) 1.21
Liver acetyl coa carboxylase: the dissociation-reassociation process and its relation to catalytic activity. Proc Natl Acad Sci U S A (1966) 1.21
Insulin-induced down-regulation of insulin receptors in 3T3-L1 adipocytes. Altered rate of receptor inactivation. J Biol Chem (1982) 1.21
Liver acetyl coenzyme A carboxylase. II. Further molecular characterization. J Biol Chem (1968) 1.21
Homogeneous functional insulin receptor from 3T3-L1 adipocytes. Purification using N alpha B1-(biotinyl-epsilon-aminocaproyl)insulin and avidin-sepharose. J Biol Chem (1985) 1.20
Transcriptional control of the stearoyl-CoA desaturase-1 gene by polyunsaturated fatty acids. Biochem Biophys Res Commun (1994) 1.18
Trans-acting factors involved in adipogenic differentiation. Curr Opin Genet Dev (1993) 1.18
Kinetics of activation of acetyl-CoA carboxylase by citrate. Relationship to the rate of polymerization of the enzyme. J Biol Chem (1983) 1.17
Insulin-dependent phosphorylation of the insulin receptor-protein kinase and activation of glucose transport in 3T3-L1 adipocytes. J Biol Chem (1986) 1.16
Synthesis of epidermal growth factor receptor in human A431 cells. Glycosylation-dependent acquisition of ligand binding activity occurs post-translationally in the endoplasmic reticulum. J Biol Chem (1986) 1.16
Repression of transcription mediated by dual elements in the CCAAT/enhancer binding protein alpha gene. Proc Natl Acad Sci U S A (1997) 1.16
Electric pulse-induced fusion of 3T3 cells in monolayer culture. Science (1982) 1.14
Derepression of the C/EBPalpha gene during adipogenesis: identification of AP-2alpha as a repressor. Proc Natl Acad Sci U S A (1998) 1.12
Molecular and catalytic properties of cytosolic acetoacetyl coenzyme A thiolase from avian liver. J Biol Chem (1973) 1.11
Actinomyces adsorption mediated by type-1 fimbriae. J Dent Res (1986) 1.11
3-Hydroxy-3-methylglutaryl coenzyme A synthase. Evidence for an acetyl-S-enzyme intermediate and identification of a cysteinyl sulfhydryl as the site of acetylation. J Biol Chem (1975) 1.10
Acetyl coenzyme A carboxylase. 3. Further studies on the relation of catalytic activity to polymeric state. J Biol Chem (1972) 1.10
Down-regulation of epidermal growth factor receptor correlates with plasminogen activator activity in human A431 epidermoid carcinoma cells. Proc Natl Acad Sci U S A (1983) 1.10
Insulin down-regulates expression of the insulin-responsive glucose transporter (GLUT4) gene: effects on transcription and mRNA turnover. Proc Natl Acad Sci U S A (1993) 1.09
High fat diet-induced hyperglycemia: prevention by low level expression of a glucose transporter (GLUT4) minigene in transgenic mice. Proc Natl Acad Sci U S A (1995) 1.09
On the possible involvement of a carbonyl phosphate intermediate in the adenosine triphosphate-dependent carboxylation of biotin. J Biol Chem (1972) 1.08
Chemical and enzymatic evidence for the participation of a 2-carboxy-3-ketoribitol-1,5-diphosphate intermediate in the carboxylation of ribulose 1,5-diphosphate. J Biol Chem (1973) 1.07
Sequential repression and activation of the CCAAT enhancer-binding protein-alpha (C/EBPalpha ) gene during adipogenesis. Proc Natl Acad Sci U S A (2000) 1.07
Suppression of preadipocyte differentiation and promotion of adipocyte death by HIV protease inhibitors. J Biol Chem (2000) 1.06