The role of the phosphate group for the structure of phosphopeptide products of adenosine 3',5'-cyclic monophosphate-dependent protein kinase.

PubWeight™: 0.79‹?›

🔗 View Article (PMC 1145081)

Published in Biochem J on July 15, 1985

Authors

R C Hider, U Ragnarsson, O Zetterqvist

Articles cited by this

Phosphorylation-dephosphorylation of enzymes. Annu Rev Biochem (1979) 11.34

Computed circular dichroism spectra for the evaluation of protein conformation. Biochemistry (1969) 10.58

The role of protein phosphorylation in neural and hormonal control of cellular activity. Nature (1982) 5.30

Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase. J Biol Chem (1977) 4.87

Solid-phase peptide synthesis. Adv Enzymol Relat Areas Mol Biol (1969) 4.30

Staphylococcal nuclease: proposed mechanism of action based on structure of enzyme-thymidine 3',5'-bisphosphate-calcium ion complex at 1.5-A resolution. Proc Natl Acad Sci U S A (1979) 2.61

Synthetic hexapeptide substrates and inhibitors of 3':5'-cyclic AMP-dependent protein kinase. Proc Natl Acad Sci U S A (1976) 1.75

The minimum substrate of cyclic AMP-stimulated protein kinase, as studied by synthetic peptides representing the phosphorylatable site of pyruvate kinase (type L) of rat liver. Biochem Biophys Res Commun (1976) 1.59

The conformation properties of proteins in solution. Biol Rev Camb Philos Soc (1979) 1.52

The structural requirements of substrates of cyclic AMP-dependent protein kinase. FEBS Lett (1982) 1.12

Structure of bis(methylguanidinium) monohydrogen orthophosphate. A model for the arginine-phosphate interactions at the active site of staphylococcal nuclease and other phosphohydrolytic enzymes. J Am Chem Soc (1974) 1.00

The effect of counterions on melittin aggregation. Biochem J (1983) 0.95

Nuclear magnetic resonance studies of the conformation and kinetics of the peptide-substrate at the active site of bovine heart protein kinase. Biochemistry (1981) 0.94

Allosteric transitions of phosphorylase a and the regulation of glycogen metabolism. J Biol Chem (1978) 0.91

[Conformation studies on oligoalanines, substance P, and the myoglobin sequence (66-73). Circular dichroism of polyethyleneglycol-bound peptides]. Biopolymers (1976) 0.83

Analysis of the surface topography of glycogen phosphorylase a: implications for metabolic interconversion and regulatory mechanisms. Can J Biochem (1979) 0.83

Detection and identification of substrates for protein kinases: use of proteins and synthetic peptides. Methods Enzymol (1984) 0.81

Phosphopeptide substrates of a phosphoprotein phosphatase from rat liver. J Biol Chem (1980) 0.80

Articles by these authors

The interaction of bee melittin with lipid bilayer membranes. Biochim Biophys Acta (1978) 1.73

Permeability of the small intestine to substances of different molecular weight. Gut (1970) 1.61

Non-transferrin-bound iron induced by myeloablative chemotherapy. Br J Haematol (1997) 1.60

The minimum substrate of cyclic AMP-stimulated protein kinase, as studied by synthetic peptides representing the phosphorylatable site of pyruvate kinase (type L) of rat liver. Biochem Biophys Res Commun (1976) 1.59

Relationship between intracellular amino acids and protein synthesis in the extensor digitorum longus muscle of rats. Biochem J (1969) 1.55

Identification in skeletal muscle of a distinct extracellular pool of amino acids, and its role in protein synthesis. Biochem J (1971) 1.55

Relative oral efficacy and acute toxicity of hydroxypyridin-4-one iron chelators in mice. Blood (1990) 1.47

Honeybee venom: a rich source of pharmacologically active peptides. Endeavour (1988) 1.47

Structural dependence of flavonoid interactions with Cu2+ ions: implications for their antioxidant properties. Biochem J (1998) 1.46

The structure of melittin in lipid bilayer membranes. Biochim Biophys Acta (1979) 1.32

Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential. J Med Chem (1993) 1.31

Snake toxin secondary structure predictions. Structure activity relationships. J Mol Biol (1977) 1.30

The relationship of intracellular iron chelation to the inhibition and regeneration of human ribonucleotide reductase. J Biol Chem (1996) 1.28

The sites of hydrolysis of dipeptides containing leucine and glycine by rat jejunum in vitro. Biochem J (1969) 1.26

Kinetics of removal and reappearance of non-transferrin-bound plasma iron with deferoxamine therapy. Blood (1996) 1.23

Studies on the coupling step in solid phase peptide synthesis. Further competition experiments and attempts to assess formation of ion pairs. J Org Chem (1974) 1.21

Purification, substrate specificity, and classification of tripeptidyl peptidase II. J Biol Chem (1986) 1.18

Tripeptidyl aminopeptidase in the extralysosomal fraction of rat liver. J Biol Chem (1983) 1.13

Non-dependence on native structure of pig liver pyruvate kinase when used as a substrate for cyclic 3',5'-AMP-stimulated protein kinase. Biochem Biophys Res Commun (1975) 1.13

Determination of non-transferrin-bound iron in genetic hemochromatosis using a new HPLC-based method. J Hepatol (2000) 1.13

The structural requirements of substrates of cyclic AMP-dependent protein kinase. FEBS Lett (1982) 1.12

Quantification of non-transferrin-bound iron in the presence of unsaturated transferrin. Anal Biochem (1999) 1.11

Structure and pharmacology of elapid cytotoxins. Pharmacol Ther (1988) 1.11

Ferric saccharate induces oxygen radical stress and endothelial dysfunction in vivo. Eur J Clin Invest (2002) 1.10

Conformational properties of the neurotoxins and cytotoxins isolated from Elapid snake venoms. CRC Crit Rev Biochem (1983) 1.08

Phosphorylation and dephosphorylation reactions of bovine brain (Na+-K+)-stimulated ATP phosphohydrolase studied by a rapid mixing technique. Biochim Biophys Acta (1974) 1.07

Amino acid sequence at the phosphorylated site of rat liver phenylalanine hydroxylase and phosphorylation of a corresponding synthetic peptide. Biochem Biophys Res Commun (1980) 1.07

A direct method for quantification of non-transferrin-bound iron. Anal Biochem (1990) 1.07

Comparative radical scavenging ability of bidentate iron (III) chelators. Biochem Pharmacol (1998) 1.05

Regulation in vitro of rat liver pyruvate kinase by phosphorylation-dephosphorylation reactions, catalyzed by cyclic-AMP dependent protein kinases and a histone phosphatase. Biochim Biophys Acta (1976) 1.03

Microcomputer application of non-linear regression analysis to metal-ligand equilibria. Talanta (1988) 1.02

Reaction of two enzyme fractions from Streptomyces griseus protease with diisopropylphosphoro-fluoridate. Acta Chem Scand (1965) 0.99

Domain preference in iron removal from human transferrin by the bacterial siderophores aerobactin and enterochelin. Eur J Biochem (1988) 0.99

Studies in vitro on free amino acid pools and protein synthesis in rat jejunum. Eur J Clin Invest (1971) 0.98

Hydroxylated phytosiderophore species possess an enhanced chelate stability and affinity for iron(III). Plant Physiol (2000) 0.98

Oral ferrous sulphate leads to a marked increase in pro-oxidant nontransferrin-bound iron. Eur J Clin Invest (2004) 0.98

Intravenous infusion pharmacokinetics of desferrioxamine in thalassaemic patients. Drug Metab Dispos (1993) 0.97

Iron mobilization from hepatocyte monolayer cultures by chelators: the importance of membrane permeability and the iron-binding constant. Blood (1988) 0.97

Supramolecular structure of tripeptidyl peptidase II from human erythrocytes as studied by electron microscopy, and its correlation to enzyme activity. Biochem J (1987) 0.97

Ocular toxicity of desferrioxamine--an example of copper promoted auto-oxidative damage? Br J Ophthalmol (1989) 0.96

The composition of black lipid membranes formed from egg-yolk lecithin, cholesterol and n-decane. Biochim Biophys Acta (1974) 0.96

Cell cycle synchronization and growth inhibition by 3-hydroxypyridin-4-one iron chelators in leukemia cell lines. Cancer Res (1992) 0.96

The effect of counterions on melittin aggregation. Biochem J (1983) 0.95

Non-transferrin-bound iron is present in serum of hereditary haemochromatosis heterozygotes. Eur J Clin Invest (2000) 0.95

The antimalarial effect of iron chelators: studies in animal models and in humans with mild falciparum malaria. J Inorg Biochem (1992) 0.94

The environment of the lipoxygenase iron binding site explored with novel hydroxypyridinone iron chelators. J Biol Chem (1996) 0.94

Investigation into the correlation between the structure of hydroxypyridinones and blood-brain barrier permeability. Biochem Pharmacol (1999) 0.94

Peptide inhibition of mammalian histidine decarboxylase. Agents Actions (1979) 0.93

Iron mobilization from myocardial cells by 3-hydroxypyridin-4-one chelators: studies in rat heart cells in culture. Blood (1991) 0.93

Nontransferrin-bound iron in the plasma of haemodialysis patients after intravenous iron saccharate infusion. Eur J Clin Invest (2002) 0.92

Preparation of crystalline nucleoside diphosphate kinase from baker's yeast and identification of 1-[32P]phosphohistidine as the main phosphorylated product of an alkaline hydrolysate of enzyme incubated with adenosine [32P]triphosphate. Eur J Biochem (1969) 0.92

Lytic activity of monomeric and oligomeric melittin. Biochim Biophys Acta (1983) 0.92

Effects of the pyrones, maltol and ethyl maltol, on iron absorption from the rat small intestine. J Pharm Pharmacol (1987) 0.92

Opiate receptor affinity of peptides related to Leu-enkephalin. Biochem Biophys Res Commun (1976) 0.92

A general procedure for analysis of proenkephalin B derived opioid peptides. Regul Pept (1985) 0.91

Iron chelators for clinical use. Met Ions Biol Syst (1998) 0.91

Effect of phospholipase A on actions of cobra venom cardiotoxins on erythrocytes and skeletal muscle. Biochim Biophys Acta (1983) 0.91

The effect of N-alkyl modification on the antimalarial activity of 3-hydroxypyridin-4-one oral iron chelators. Blood (1991) 0.91

Flow cytometric assessment of hydroxypyridinone iron chelators on in vitro growth of drug-resistant malaria. Cytometry (1997) 0.90

Absorption of iron from ferric hydroxypyranone complexes. Br J Nutr (1994) 0.90

In vivo evaluation of hydroxypyridone iron chelators in a mouse model. Acta Haematol (1987) 0.90

Novel 3-hydroxy-2(1H)-pyridinones. Synthesis, iron(III)-chelating properties, and biological activity. J Med Chem (1990) 0.90

Synthesis of 2-amido-3-hydroxypyridin-4(1H)-ones: novel iron chelators with enhanced pFe3+ values. Bioorg Med Chem (2001) 0.90

Investigation of the anti-inflammatory properties of hydroxypyridinones. Ann Rheum Dis (1989) 0.88

Conformational properties of phospholipases A2. Secondary-structure prediction, circular dichroism and relative interface hydrophobicity. Eur J Biochem (1983) 0.88

The importance of reductive mechanisms for intestinal uptake of iron from ferric maltol and ferric nitrilotriacetic acid (NTA). J Pharm Pharmacol (1990) 0.88

Release of iron from ferritin molecules and their iron-cores by 3-hydroxypyridinone chelators in vitro. J Inorg Biochem (1989) 0.87

Comparison of the subacute toxicity and efficacy of 3-hydroxypyridin-4-one iron chelators in overloaded and nonoverloaded mice. Blood (1991) 0.87

The influence of melittin on the rotation of band 3 protein in the human erythrocyte membrane. Eur Biophys J (1984) 0.87

Protein-bound phosphorylthreonine in some tissues and organisms. Biochim Biophys Acta (1970) 0.87

Characteristics of iron(III) uptake by isolated fragments of rat small intestine in the presence of the hydroxypyrones, maltol and ethyl maltol. Biochem Pharmacol (1988) 0.86

Structure-activity investigation of the inhibition of 3-hydroxypyridin-4-ones on mammalian tyrosine hydroxylase. Biochem Pharmacol (2001) 0.86

Cobra cardiotoxins. Purification, effects on skeletal muscle and structure/activity relationships [published errtum appears in Eur J Biochem 1988 Feb 1;171(3):727]. Eur J Biochem (1987) 0.86

Active site of tripeptidyl peptidase II from human erythrocytes is of the subtilisin type. Proc Natl Acad Sci U S A (1987) 0.86

Phosphorylation of bovine brain Na + , K + -stimulated ATP phosphohydrolase by adenosine ( 32 P)triphosphate studied by a rapid-mixing technique. Biochim Biophys Acta (1972) 0.86

Amino acid sequence at the phosphorylated site of rat liver fructose-1,6-diphosphatase and phosphorylation of a corresponding synthetic peptide. Biochem Biophys Res Commun (1979) 0.85

The effect of synthetic polymers on the electrical and permeability properties of lipid membranes. Biochim Biophys Acta (1978) 0.85

Colorimetric detection of the hydroxyl radical: comparison of the hydroxyl-radical-generating ability of various iron complexes. Anal Biochem (1988) 0.85

Modulation of GABA-mediated synaptic transmission by endogenous zinc in the immature rat hippocampus in vitro. J Physiol (1994) 0.85

Amino acid sequence at the phosphorylated site of rat liver pyruvate kinase. Biochem Biophys Res Commun (1975) 0.85

Chelating agents for the treatment of systemic iron overload. Curr Med Chem (2012) 0.85

Chelation and mobilization of cellular iron by different classes of chelators. Mol Pharmacol (1997) 0.84

Reconstitution of cytochrome c oxidase in phospholipid vesicles containing polyvinylic polymers. Biochem J (1989) 0.84

Use of a dehydroalanine-containing peptide as an efficient inhibitor of tripeptidyl peptidase II. Arch Biochem Biophys (1994) 0.84

Molecular conformation of alpha-cobratoxin as studied by nuclear magnetic resonance and circular dichroism. J Mol Biol (1982) 0.84

Effects of oxidative stress on some physiochemical properties of caeruloplasmin. Biochem J (1989) 0.83

The effect of insulin on free amino acid pools and protein synthesis in rat skeletal muscle in vitro. Biochem J (1971) 0.83

Human immunodeficiency virus type 1 replication inhibition by the bidentate iron chelators CP502 and CP511 is caused by proliferation inhibition and the onset of apoptosis. Eur J Clin Invest (2002) 0.83

Absorption of low and therapeutic doses of ferric maltol, a novel ferric iron compound, in iron deficient subjects using a single dose iron absorption test. J Clin Pharm Ther (1991) 0.83

The conformation of apamin. FEBS Lett (1986) 0.83

Urinary metabolic profiles in human and rat of 1,2-dimethyl- and 1,2-diethyl-substituted 3-hydroxypyridin-4-ones. Drug Metab Dispos (1992) 0.83

The development of iron chelating drugs. Baillieres Clin Haematol (1989) 0.83

Poly(vinyl alcohol) nanoparticle stability in biological media and uptake in respiratory epithelial cell layers in vitro. Eur J Pharm Biopharm (2009) 0.82

Isolation of N-e-[32P]phosphoryl-lysine from rat-liver cell sap after incubation with [32P]adenosine triphosphate. Biochim Biophys Acta (1967) 0.82

Classification of phospholipases A2 according to sequence. Evolutionary and pharmacological implications. Eur J Biochem (1983) 0.82

Synthesis, physicochemical properties, and evaluation of N-substituted-2-alkyl-3-hydroxy-4(1H)-pyridinones. J Med Chem (1998) 0.82