Initiation of poliovirus plus-strand RNA synthesis in a membrane complex of infected HeLa cells.

PubWeight™: 3.24‹?› | Rank: Top 1%

🔗 View Article (PMC 253900)

Published in J Virol on October 01, 1986

Authors

N Takeda, R J Kuhn, C F Yang, T Takegami, E Wimmer

Articles citing this

Switch from translation to RNA replication in a positive-stranded RNA virus. Genes Dev (1998) 4.59

Cellular origin and ultrastructure of membranes induced during poliovirus infection. J Virol (1996) 4.41

Structural organization of poliovirus RNA replication is mediated by viral proteins of the P2 genomic region. J Virol (1990) 3.73

Structural and functional characterization of the poliovirus replication complex. J Virol (1992) 3.70

Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A. EMBO J (1995) 3.54

Formation of plant RNA virus replication complexes on membranes: role of an endoplasmic reticulum-targeted viral protein. EMBO J (1997) 2.99

Inhibition of poliovirus RNA synthesis by brefeldin A. J Virol (1992) 2.96

Complete nucleotide sequence of infectious Coxsackievirus B3 cDNA: two initial 5' uridine residues are regained during plus-strand RNA synthesis. J Virol (1990) 2.68

Complete replication of poliovirus in vitro: preinitiation RNA replication complexes require soluble cellular factors for the synthesis of VPg-linked RNA. J Virol (1995) 2.67

Cellular COPII proteins are involved in production of the vesicles that form the poliovirus replication complex. J Virol (2001) 2.55

Role of a viral membrane polypeptide in strand-specific initiation of poliovirus RNA synthesis. J Virol (1991) 2.44

Demonstration in vitro of temperature-sensitive elongation of RNA in Sindbis virus mutant ts6. J Virol (1988) 2.28

Oligomeric structures of poliovirus polymerase are important for function. EMBO J (2001) 2.27

Analysis of RNA synthesis of type 1 poliovirus by using an in vitro molecular genetic approach. J Virol (1987) 2.14

Active complete in vitro replication of nodavirus RNA requires glycerophospholipid. Proc Natl Acad Sci U S A (1992) 2.12

Capsid protein VP4 of poliovirus is N-myristoylated. Proc Natl Acad Sci U S A (1987) 2.12

Synchronous replication of poliovirus RNA: initiation of negative-strand RNA synthesis requires the guanidine-inhibited activity of protein 2C. J Virol (1997) 2.04

Purification and properties of poliovirus RNA polymerase expressed in Escherichia coli. J Virol (1989) 2.00

Kissing of the two predominant hairpin loops in the coxsackie B virus 3' untranslated region is the essential structural feature of the origin of replication required for negative-strand RNA synthesis. J Virol (1997) 1.95

Phospholipid biosynthesis and poliovirus genome replication, two coupled phenomena. EMBO J (1990) 1.88

Complete protein linkage map of poliovirus P3 proteins: interaction of polymerase 3Dpol with VPg and with genetic variants of 3AB. J Virol (1998) 1.85

cis-acting lesions targeted to the hydrophobic domain of a poliovirus membrane protein involved in RNA replication. J Virol (1992) 1.74

Picornavirus nonstructural proteins: emerging roles in virus replication and inhibition of host cell functions. J Virol (1993) 1.72

A new cis-acting element for RNA replication within the 5' noncoding region of poliovirus type 1 RNA. J Virol (1995) 1.70

Characterization of poliovirus clones containing lethal and nonlethal mutations in the genome-linked protein VPg. J Virol (1990) 1.69

Reversible dissociation of the poliovirus replication complex: functions and interactions of its components in viral RNA synthesis. J Virol (1996) 1.65

Construction of a "mutagenesis cartridge" for poliovirus genome-linked viral protein: isolation and characterization of viable and nonviable mutants. Proc Natl Acad Sci U S A (1988) 1.61

The 5'-terminal nucleotides of hepatitis A virus RNA, but not poliovirus RNA, are required for infectivity. J Virol (1991) 1.55

RNA duplex unwinding activity of poliovirus RNA-dependent RNA polymerase 3Dpol. J Virol (1993) 1.51

Preferred sites of recombination in poliovirus RNA: an analysis of 40 intertypic cross-over sequences. Nucleic Acids Res (1988) 1.49

Poliovirus 2C region functions during encapsidation of viral RNA. J Virol (1997) 1.44

Genetic analysis of a hydrophobic domain of coxsackie B3 virus protein 2B: a moderate degree of hydrophobicity is required for a cis-acting function in viral RNA synthesis. J Virol (1995) 1.43

Poliovirus cre(2C)-dependent synthesis of VPgpUpU is required for positive- but not negative-strand RNA synthesis. J Virol (2003) 1.43

Membranous replication factories induced by plus-strand RNA viruses. Viruses (2014) 1.40

Inefficient complementation activity of poliovirus 2C and 3D proteins for rescue of lethal mutations. J Virol (1995) 1.40

Poliovirus protein 3AB forms a complex with and stimulates the activity of the viral RNA polymerase, 3Dpol. J Virol (1995) 1.37

The antiviral compound enviroxime targets the 3A coding region of rhinovirus and poliovirus. J Virol (1995) 1.37

Expression and subcellular localization of poliovirus VPg-precursor protein 3AB in eukaryotic cells: evidence for glycosylation in vitro. J Virol (1994) 1.36

Brefeldin A inhibits cell-free, de novo synthesis of poliovirus. J Virol (1998) 1.35

A cysteine-rich motif in poliovirus protein 2C(ATPase) is involved in RNA replication and binds zinc in vitro. J Virol (2000) 1.35

Vectorial release of poliovirus from polarized human intestinal epithelial cells. J Virol (1993) 1.34

Poliovirus infection enhances the formation of two ribonucleoprotein complexes at the 3' end of viral negative-strand RNA. J Virol (1995) 1.34

Effects of temperature and lipophilic agents on poliovirus formation and RNA synthesis in a cell-free system. J Virol (1993) 1.34

Rescue of defective poliovirus RNA replication by 3AB-containing precursor polyproteins. J Virol (1998) 1.33

Replication of poliovirus in Xenopus oocytes requires two human factors. EMBO J (1996) 1.31

Detection of viral proteins after infection of cultured hepatocytes with rabbit hemorrhagic disease virus. J Virol (1998) 1.30

Host factor-induced template modification during synthesis of poliovirus RNA in vitro. J Virol (1987) 1.29

A single amino acid substitution in nonstructural protein 3A can mediate adaptation of foot-and-mouth disease virus to the guinea pig. J Virol (2001) 1.29

Replication of poliovirus RNA containing two VPg coding sequences leads to a specific deletion event. J Virol (1993) 1.24

The transformation of enterovirus replication structures: a three-dimensional study of single- and double-membrane compartments. MBio (2011) 1.21

In vitro RNA replication directed by replicase complexes isolated from the subgenomic replicon cells of hepatitis C virus. J Virol (2003) 1.20

Coxsackie B3 virus protein 2B contains cationic amphipathic helix that is required for viral RNA replication. J Virol (1996) 1.17

Expression, purification, and properties of recombinant encephalomyocarditis virus RNA-dependent RNA polymerase. J Virol (1991) 1.14

Measurement of poliovirus RNA polymerase binding to poliovirion and nonviral RNAs using a filter-binding assay. Nucleic Acids Res (1988) 1.11

The hepatitis C virus NS5A inhibitor (BMS-790052) alters the subcellular localization of the NS5A non-structural viral protein. Virology (2011) 1.10

Membrane requirements for uridylylation of the poliovirus VPg protein and viral RNA synthesis in vitro. J Virol (2003) 1.10

Membrane topography of the hydrophobic anchor sequence of poliovirus 3A and 3AB proteins and the functional effect of 3A/3AB membrane association upon RNA replication. Biochemistry (2007) 1.07

Cell-free synthesis of encephalomyocarditis virus. J Virol (2003) 1.07

Sequence determinants of 3A-mediated resistance to enviroxime in rhinoviruses and enteroviruses. J Virol (1996) 1.03

Action of 3-methylquercetin on poliovirus RNA replication. J Virol (1987) 0.98

Temperature-sensitive mouse cell factors for strand-specific initiation of poliovirus RNA synthesis. J Virol (1993) 0.96

Strand-specific RNA synthesis defects in a poliovirus with a mutation in protein 3A. J Virol (2003) 0.94

Insight into poliovirus genome replication and encapsidation obtained from studies of 3B-3C cleavage site mutants. J Virol (2009) 0.93

Stimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro. Virol J (2005) 0.90

Recombination of poliovirus RNA proceeds in mixed replication complexes originating from distinct replication start sites. J Virol (2002) 0.88

A Structural Overview of RNA-Dependent RNA Polymerases from the Flaviviridae Family. Int J Mol Sci (2015) 0.86

Mutations in the 2C region of poliovirus responsible for altered sensitivity to benzimidazole derivatives. J Virol (2000) 0.86

Initiation of protein-primed picornavirus RNA synthesis. Virus Res (2015) 0.84

Mutagenesis of the coxsackie B3 virus 2B/2C cleavage site: determinants of processing efficiency and effects on viral replication. J Virol (1996) 0.84

Poliovirus snapback double-stranded RNA isolated from infected HeLa cells is deficient in poly(A). J Virol (1987) 0.81

Three-dimensional model of the potyviral genome-linked protein. Proc Natl Acad Sci U S A (1996) 0.81

Articles cited by this

Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

A new method for sequencing DNA. Proc Natl Acad Sci U S A (1977) 250.51

Mapping adenines, guanines, and pyrimidines in RNA. Nucleic Acids Res (1977) 26.63

Primary structure, gene organization and polypeptide expression of poliovirus RNA. Nature (1981) 16.61

Phy M: an RNase activity specific for U and A residues useful in RNA sequence analysis. Nucleic Acids Res (1980) 8.18

Covalent linkage of a protein to a defined nucleotide sequence at the 5'-terminus of virion and replicative intermediate RNAs of poliovirus. Proc Natl Acad Sci U S A (1977) 8.12

A protein covalently linked to poliovirus genome RNA. Proc Natl Acad Sci U S A (1977) 7.92

The location of the polio genome protein in viral RNAs and its implication for RNA synthesis. Nature (1977) 5.61

Proteolytic processing of poliovirus polypeptides: antibodies to polypeptide P3-7c inhibit cleavage at glutamine-glycine pairs. Proc Natl Acad Sci U S A (1982) 5.50

Polyadenylic acid at the 3'-terminus of poliovirus RNA. Proc Natl Acad Sci U S A (1972) 5.42

Systematic nomenclature of picornavirus proteins. J Virol (1984) 5.26

O4-(5'-uridylyl)tyrosine is the bond between the genome-linked protein and the RNA of poliovirus. Proc Natl Acad Sci U S A (1978) 4.68

Protein is linked to the 5' end of poliovirus RNA by a phosphodiester linkage to tyrosine. J Biol Chem (1978) 4.17

The 5'-terminal structures of poliovirion RNA and poliovirus mRNA differ only in the genome-linked protein VPg. Proc Natl Acad Sci U S A (1977) 3.97

Poliovirus-specific primer-dependent RNA polymerase able to copy poly(A). Proc Natl Acad Sci U S A (1977) 3.69

Membrane-dependent uridylylation of the genome-linked protein VPg of poliovirus. Proc Natl Acad Sci U S A (1983) 3.58

The role of cytoplasmic membranes in poliovirus biosynthesis. Virology (1970) 3.46

Membrane fractions active in poliovirus RNA replication contain VPg precursor polypeptides. Virology (1983) 3.28

Dependence of the activity of the poliovirus replicase on the host cell protein. Cell (1980) 3.18

A membrane-associated precursor to poliovirus VPg identified by immunoprecipitation with antibodies directed against a synthetic heptapeptide. Cell (1982) 3.07

Genome-linked proteins of viruses. Cell (1982) 3.02

Poliovirus replication proteins: RNA sequence encoding P3-1b and the sites of proteolytic processing. Proc Natl Acad Sci U S A (1981) 2.91

Intracellular distribution of poliovirus proteins and the induction of virus-specific cytoplasmic structures. Virology (1983) 2.79

Identification of a protein linked to nascent poliovirus RNA and to the polyuridylic acid of negative-strand RNA. J Virol (1978) 2.54

Replication of picornaviruses. I. Evidence from in vitro RNA synthesis that poly(A) of the poliovirus genome is genetically coded. J Virol (1975) 2.42

A micromethod for detailed characterization of high molecular weight RNA. Methods Enzymol (1980) 2.36

Isolation of a soluble and template-dependent poliovirus RNA polymerase that copies virion RNA in vitro. J Virol (1979) 2.21

"Fingerprinting" high molecular weight RNA by two-dimensional gel electrophoresis: application to poliovirus RNA. Nucleic Acids Res (1976) 2.20

Kinetics and location of poliovirus macromolecular synthesis in correlation to virus-induced cytopathology. Virology (1980) 2.13

Poliovirus RNA-dependent RNA polymerase and host cell protein synthesize product RNA twice the size of poliovirion RNA in vitro. J Virol (1985) 2.11

Genome-length copies of poliovirion RNA are synthesized in vitro by the poliovirus RNA-dependent RNA polymerase. J Biol Chem (1982) 2.02

In vitro copying of viral positive strand RNA by poliovirus replicase. Characterization of the reaction and its products. J Biol Chem (1982) 1.96

Characterization of poliovirus-specific structures associated with cytoplasmic membranes. Virology (1970) 1.95

Poly(U) in poliovirus minus RNA is 5'-terminal. Biochem Biophys Res Commun (1974) 1.88

Poliovirus replicase stimulation by terminal uridylyl transferase. J Biol Chem (1985) 1.81

Purification of a terminal uridylyltransferase that acts as host factor in the in vitro poliovirus replicase reaction. Proc Natl Acad Sci U S A (1986) 1.80

Sequence studies of poliovirus RNA. IV. Nucleotide sequence complexities of poliovirus type 1, type 2 and two type 1 defective interfering particles RNAs, and fingerprint of the poliovirus type 3 genome. J Gen Virol (1979) 1.68

The host protein required for in vitro replication of poliovirus is a protein kinase that phosphorylates eukaryotic initiation factor-2. Cell (1985) 1.64

Association of poliovirus proteins with the endoplasmic reticulum. J Virol (1984) 1.57

Comparison of replication complexes synthesizing poliovirus RNA. Virology (1981) 1.55

The formation of poliovirus particles in association with the RNA replication complexes. J Gen Virol (1973) 1.23

In vivo and in vitro synthesis of human rhinovirus type 2 ribonucleic acid. J Virol (1972) 1.18

Antibody to poliovirus genome-linked protein (VPg) precipitates in vitro synthesized RNA attached to VPg-precursor polypeptide(s). Virus Res (1984) 1.15

Chemical and enzymatic characteristics of cytoplasmic membranes of poliovirus-infected HeLa cells. Virology (1972) 1.11

Kinetics of appearance of the products of poliovirus-induced RNA polymerase. Virology (1970) 1.08

The structure of poliovirus replicative form. Nucleic Acids Res (1980) 1.07

Heterogeneity of the 3' end of minus-strand RNA in the poliovirus replicative form. J Virol (1980) 1.04

Palindrome-like dimers of double-stranded RNA of encephalomyocarditis virus. Virology (1980) 1.01

Nucleotide sequences adjacent to the proteins covalently linked to the cowpea mosaic virus genome. Sequence determination after labelling in vitro using RNA ligase. Eur J Biochem (1979) 1.01

Interconversion of linear and circular forms of double-stranded RNA of encephalomyocarditis virus. Virology (1979) 0.84

Articles by these authors

Primary structure, gene organization and polypeptide expression of poliovirus RNA. Nature (1981) 16.61

A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. J Virol (1988) 13.93

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature (1995) 11.06

Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily. Cell (1989) 9.82

Synthesis of infectious poliovirus RNA by purified T7 RNA polymerase. Proc Natl Acad Sci U S A (1986) 8.59

A protein covalently linked to poliovirus genome RNA. Proc Natl Acad Sci U S A (1977) 7.92

The 5' end of poliovirus mRNA is not capped with m7G(5')ppp(5')Np. Proc Natl Acad Sci U S A (1976) 7.26

Initiation of protein synthesis by internal entry of ribosomes into the 5' nontranslated region of encephalomyocarditis virus RNA in vivo. J Virol (1989) 7.01

Viral proteinases. Annu Rev Biochem (1988) 6.76

Cap-independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein. Genes Dev (1990) 6.64

The separation of soluble ribonucleic acids on benzoylated diethylaminoethylcellulose. Biochemistry (1967) 6.04

The location of the polio genome protein in viral RNAs and its implication for RNA synthesis. Nature (1977) 5.61

A second virus-encoded proteinase involved in proteolytic processing of poliovirus polyprotein. Cell (1986) 5.53

Proteolytic processing of poliovirus polypeptides: antibodies to polypeptide P3-7c inhibit cleavage at glutamine-glycine pairs. Proc Natl Acad Sci U S A (1982) 5.50

Polyadenylic acid at the 3'-terminus of poliovirus RNA. Proc Natl Acad Sci U S A (1972) 5.42

Systematic nomenclature of picornavirus proteins. J Virol (1984) 5.26

Cell-free, de novo synthesis of poliovirus. Science (1991) 5.09

A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein. Proc Natl Acad Sci U S A (1993) 4.71

O4-(5'-uridylyl)tyrosine is the bond between the genome-linked protein and the RNA of poliovirus. Proc Natl Acad Sci U S A (1978) 4.68

In vitro translation of poliovirus RNA: utilization of internal initiation sites in reticulocyte lysate. J Virol (1984) 4.54

Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220. J Virol (1987) 4.52

Production of infectious poliovirus from cloned cDNA is dramatically increased by SV40 transcription and replication signals. Nucleic Acids Res (1984) 4.19

The 5'-terminal structures of poliovirion RNA and poliovirus mRNA differ only in the genome-linked protein VPg. Proc Natl Acad Sci U S A (1977) 3.97

Genetic analysis of the attenuation phenotype of poliovirus type 1. J Virol (1986) 3.94

A novel ES cell line, TT2, with high germline-differentiating potency. Anal Biochem (1993) 3.79

Defective interfering particles of poliovirus. I. Isolation and physical properties. J Virol (1971) 3.74

Nucleocapsid and glycoprotein organization in an enveloped virus. Cell (1995) 3.66

Protein-primed RNA synthesis by purified poliovirus RNA polymerase. Nature (1998) 3.64

Identification of the initiation site of poliovirus polyprotein synthesis. J Virol (1982) 3.62

Membrane-dependent uridylylation of the genome-linked protein VPg of poliovirus. Proc Natl Acad Sci U S A (1983) 3.58

Interaction of poliovirus polypeptide 3CDpro with the 5' and 3' termini of the poliovirus genome. Identification of viral and cellular cofactors needed for efficient binding. J Biol Chem (1994) 3.45

Priming for and induction of anti-poliovirus neutralizing antibodies by synthetic peptides. Nature (1983) 3.35

Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection. Proc Natl Acad Sci U S A (1990) 3.31

The poliovirus receptor protein is produced both as membrane-bound and secreted forms. EMBO J (1990) 3.31

Membrane fractions active in poliovirus RNA replication contain VPg precursor polypeptides. Virology (1983) 3.28

Guanidine-selected mutants of poliovirus: mapping of point mutations to polypeptide 2C. J Virol (1986) 3.15

Identification of an RNA hairpin in poliovirus RNA that serves as the primary template in the in vitro uridylylation of VPg. J Virol (2000) 3.14

A membrane-associated precursor to poliovirus VPg identified by immunoprecipitation with antibodies directed against a synthetic heptapeptide. Cell (1982) 3.07

Poliovirus host range is determined by a short amino acid sequence in neutralization antigenic site I. Science (1988) 3.03

Genome-linked proteins of viruses. Cell (1982) 3.02

Similarity in gene organization and homology between proteins of animal picornaviruses and a plant comovirus suggest common ancestry of these virus families. Nucleic Acids Res (1984) 2.99

Implications of the picornavirus capsid structure for polyprotein processing. Proc Natl Acad Sci U S A (1987) 2.99

Poliovirus polypeptide precursors: expression in vitro and processing by exogenous 3C and 2A proteinases. Proc Natl Acad Sci U S A (1987) 2.98

Poliovirus replication proteins: RNA sequence encoding P3-1b and the sites of proteolytic processing. Proc Natl Acad Sci U S A (1981) 2.91

Translation of poliovirus RNA: role of an essential cis-acting oligopyrimidine element within the 5' nontranslated region and involvement of a cellular 57-kilodalton protein. J Virol (1991) 2.86

Complete nucleotide sequence and genetic organization of Aichi virus, a distinct member of the Picornaviridae associated with acute gastroenteritis in humans. J Virol (1998) 2.85

Poliovirus chimeras replicating under the translational control of genetic elements of hepatitis C virus reveal unusual properties of the internal ribosomal entry site of hepatitis C virus. Proc Natl Acad Sci U S A (1996) 2.78

Internal ribosomal entry site substitution eliminates neurovirulence in intergeneric poliovirus recombinants. Proc Natl Acad Sci U S A (1996) 2.71

Mouse Otx2 functions in the formation and patterning of rostral head. Genes Dev (1995) 2.70

Poliovirus neutralization epitopes: analysis and localization with neutralizing monoclonal antibodies. J Virol (1982) 2.63

A source of error in phenylketonuria screening. Am J Clin Pathol (1988) 2.59

Sequence studies of poliovirus RNA. I. Characterization of the 5'-terminus. J Mol Biol (1972) 2.56

Chorea-ballismus with nonketotic hyperglycemia in primary diabetes mellitus. AJNR Am J Neuroradiol (1996) 2.54

Sindbis virus RNA polymerase is degraded by the N-end rule pathway. Proc Natl Acad Sci U S A (1991) 2.52

Cap-independent translation of picornavirus RNAs: structure and function of the internal ribosomal entry site. Enzyme (1990) 2.51

Nucleocapsid-glycoprotein interactions required for assembly of alphaviruses. J Virol (1994) 2.47

Interaction between the 5'-terminal cloverleaf and 3AB/3CDpro of poliovirus is essential for RNA replication. J Virol (1995) 2.47

Identification of a protein binding site on the surface of the alphavirus nucleocapsid and its implication in virus assembly. Structure (1996) 2.46

High-affinity laminin receptor is a receptor for Sindbis virus in mammalian cells. J Virol (1992) 2.44

Interaction of the poliovirus receptor with poliovirus. Proc Natl Acad Sci U S A (2000) 2.42

Replication of picornaviruses. I. Evidence from in vitro RNA synthesis that poly(A) of the poliovirus genome is genetically coded. J Virol (1975) 2.42

Stable hairpin structure within the 5'-terminal 85 nucleotides of poliovirus RNA. J Virol (1981) 2.40

Parthenogenetic activation of oocytes in c-mos-deficient mice. Nature (1994) 2.40

Protein processing map of poliovirus. J Virol (1984) 2.33

Production of guanidine-resistant and -dependent poliovirus mutants from cloned cDNA: mutations in polypeptide 2C are directly responsible for altered guanidine sensitivity. J Virol (1986) 2.33

The cellular polypeptide p57 (pyrimidine tract-binding protein) binds to multiple sites in the poliovirus 5' nontranslated region. J Virol (1994) 2.29

Expression of a cloned gene segment of poliovirus in E. coli: evidence for autocatalytic production of the viral proteinase. Cell (1984) 2.29

In vitro phenotypic markers of a poliovirus recombinant constructed from infectious cDNA clones of the neurovirulent Mahoney strain and the attenuated Sabin 1 strain. J Virol (1985) 2.26

Enhanced proliferative potential in culture of cells from p53-deficient mice. Oncogene (1993) 2.25

Expression and self-assembly of empty virus-like particles of hepatitis E virus. J Virol (1997) 2.25

Functional basis of poliovirus neutralization determined with monospecific neutralizing antibodies. J Virol (1983) 2.24

Group-specific identification of polioviruses by PCR using primers containing mixed-base or deoxyinosine residue at positions of codon degeneracy. J Clin Microbiol (1996) 2.23

Central nervous pathway for acupuncture stimulation: localization of processing with functional MR imaging of the brain--preliminary experience. Radiology (1999) 2.23

Mesodermal defect in late phase of gastrulation by a targeted mutation of focal adhesion kinase, FAK. Oncogene (1995) 2.22

"Fingerprinting" high molecular weight RNA by two-dimensional gel electrophoresis: application to poliovirus RNA. Nucleic Acids Res (1976) 2.20

Genetic and biochemical studies of poliovirus cis-acting replication element cre in relation to VPg uridylylation. J Virol (2000) 2.18

Bivalent attachment of antibody onto poliovirus leads to conformational alteration and neutralization. J Virol (1983) 2.18

Polioviruses containing picornavirus type 1 and/or type 2 internal ribosomal entry site elements: genetic hybrids and the expression of a foreign gene. Proc Natl Acad Sci U S A (1994) 2.17

Analysis of RNA synthesis of type 1 poliovirus by using an in vitro molecular genetic approach. J Virol (1987) 2.14

Capsid protein VP4 of poliovirus is N-myristoylated. Proc Natl Acad Sci U S A (1987) 2.12

Carboxy-terminal analysis of poliovirus proteins: termination of poliovirus RNA translation and location of unique poliovirus polyprotein cleavage sites. J Virol (1982) 2.11

Cardioviral internal ribosomal entry site is functional in a genetically engineered dicistronic poliovirus. Nature (1992) 2.10

Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system. Proc Natl Acad Sci U S A (1996) 2.10

Processing of in vitro-synthesized gag precursor proteins of human immunodeficiency virus (HIV) type 1 by HIV proteinase generated in Escherichia coli. J Virol (1988) 2.09

Poliovirus proteinase 3C: large-scale expression, purification, and specific cleavage activity on natural and synthetic substrates in vitro. J Virol (1988) 2.09

Intergeneric poliovirus recombinants for the treatment of malignant glioma. Proc Natl Acad Sci U S A (2000) 2.08

In vivo newly translated polypeptides are sequestered in a protected folding environment. EMBO J (1999) 2.08

Poliovirus proteinase 3C converts an active form of transcription factor IIIC to an inactive form: a mechanism for inhibition of host cell polymerase III transcription by poliovirus. EMBO J (1991) 2.07

Properties of purified recombinant poliovirus protein 3aB as substrate for viral proteinases and as co-factor for RNA polymerase 3Dpol. J Biol Chem (1994) 2.07

Poliovirus type 1/type 3 antigenic hybrid virus constructed in vitro elicits type 1 and type 3 neutralizing antibodies in rabbits and monkeys. Proc Natl Acad Sci U S A (1988) 2.07

Cleavage sites in the polypeptide precursors of poliovirus protein P2-X. Virology (1981) 2.04

Sequence studies of poliovirus RNA. III. Polyuridylic acid and polyadenylic acid as components of the purified poliovirus replicative intermediate. J Mol Biol (1975) 2.04

Proteolytic processing of polyproteins in the replication of RNA viruses. Biochemistry (1989) 2.04