Published in J Immunol on November 01, 1986
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Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility. Proc Natl Acad Sci U S A (1988) 4.19
Pocket 4 of the HLA-DR(alpha,beta 1*0401) molecule is a major determinant of T cells recognition of peptide. J Exp Med (1995) 1.28
Immunological suppression by human CD8+ T cells is receptor dependent and HLA-DQ restricted. Proc Natl Acad Sci U S A (1991) 1.12
Structural analysis of the HLA-DR, -DQ, and -DP alleles on the celiac disease-associated HLA-DR3 (DRw17) haplotype. Proc Natl Acad Sci U S A (1989) 1.02
Presentation of an immunodominant T-cell epitope of hepatitis B surface antigen by the HLA-DPw4 molecule. J Virol (1989) 0.91
Understanding the molecular basis of coeliac disease. Gut (1990) 0.90
The role of polymorphic HLA-DR beta chain residues in presentation of viral antigens to T cells. J Exp Med (1990) 0.81
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The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum (1987) 14.21
Psychiatric screening in general practice. A controlled trial. Lancet (1976) 5.29
Maintaining low HIV seroprevalence in populations of injecting drug users. JAMA (1995) 4.88
A genomewide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases. Am J Hum Genet (2001) 4.17
High-density SNP analysis of 642 Caucasian families with rheumatoid arthritis identifies two new linkage regions on 11p12 and 2q33. Genes Immun (2006) 3.86
Epidemiology and detection of HIV-1 among pregnant women in the United Kingdom: results from national surveillance 1988-96. BMJ (1998) 3.85
Outbreak of HIV infection in a Scottish prison. BMJ (1995) 3.82
Laboratory studies with a selective Enterococcus medium. Appl Microbiol (1970) 3.70
Confidence limits for estimates of gene linkage based on analysis of recombinant inbred strains. J Hered (1986) 3.68
Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice. Immunity (1996) 3.33
Analysis of host-virus interactions in AIDS with anti-gp120 T cell clones: effect of HIV sequence variation and a mechanism for CD4+ cell depletion. Cell (1988) 3.25
The value of feedback in teaching interviewing skills to medical students. Psychol Med (1978) 3.24
Computerized, interactive, multimedia cognitive-behavioural program for anxiety and depression in general practice. Psychol Med (2003) 3.15
Improving the psychiatric skills of the general practice trainee: an evaluation of a group training course. Med Educ (1988) 3.08
Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4. J Immunol (1995) 3.06
Shortened telomeres in clonally expanded CD28-CD8+ T cells imply a replicative history that is distinct from their CD28+CD8+ counterparts. J Immunol (1996) 3.03
Regeneration of adult axons in white matter tracts of the central nervous system. Nature (1998) 2.94
The genetics revolution and the assault on rheumatoid arthritis. Arthritis Rheum (1999) 2.92
Tumor antigens induced by nontransforming mutants of polyoma virus. Cell (1978) 2.92
Positive selection of natural autoreactive B cells. Science (1999) 2.91
RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response. Genes Immun (2002) 2.88
Improving the psychiatric skills of established general practitioners: evaluation of group teaching. Med Educ (1987) 2.85
Mental health care training priorities in general practice. Br J Gen Pract (1997) 2.79
Clonal predominance of T cell receptors within the CD8+ CD45RO+ subset in normal human subjects. J Immunol (1993) 2.73
Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes. J Neurosci (1991) 2.73
Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2. Proc Natl Acad Sci U S A (1996) 2.71
Use of the general health questionnaire in clinical work. Br Med J (Clin Res Ed) (1986) 2.68
Robust regeneration of adult sensory axons in degenerating white matter of the adult rat spinal cord. J Neurosci (1999) 2.64
Identifying psychiatric illness among general medical patients. Br Med J (Clin Res Ed) (1985) 2.63
Improving outcomes in depression. BMJ (2001) 2.62
Screening for psychiatric illness in general practice: the general practitioner versus the screening questionnaire. J R Coll Gen Pract (1987) 2.60
Statistical considerations for linkage analysis using recombinant inbred strains and backcrosses. Proc Natl Acad Sci U S A (1986) 2.60
A new method of estimating prevalence of injecting drug use in an urban population: results from a Scottish city. Int J Epidemiol (1991) 2.49
The pathways to psychiatric care: a cross-cultural study. Psychol Med (1991) 2.49
The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status. Genes Immun (2005) 2.47
Mortality and survival among a cohort of drug injectors in Glasgow, 1982-1994. Addiction (1997) 2.45
Cellular and molecular mechanisms of glial scarring and progressive cavitation: in vivo and in vitro analysis of inflammation-induced secondary injury after CNS trauma. J Neurosci (1999) 2.43
How psychiatric disorders are missed during medical consultations. Lancet (1987) 2.41
Molecular diversity of HLA-DR4 haplotypes. Proc Natl Acad Sci U S A (1986) 2.40
Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer. Br J Cancer (2009) 2.39
Clinical follow-up and immunogenetic studies of 32 patients with eosinophilia-myalgia syndrome. Lancet (1991) 2.31
Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone. J Exp Med (1996) 2.28
Two pigment proteins in spinach chloroplasts. Biochim Biophys Acta (1966) 2.27
Antigen-presenting capabilities of human monocytes correlates with their expression of HLA-DS, an Ia determinant distinct from HLA-DR. J Immunol (1983) 2.25
A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis. Genes Immun (2002) 2.21
Sulfated proteoglycans in astroglial barriers inhibit neurite outgrowth in vitro. Exp Neurol (1990) 2.19
Clinical and patient satisfaction outcomes of a new treatment for somatized mental disorder taught to general practitioners. Br J Gen Pract (1999) 2.18
Mortality among injecting drug users: a critical reappraisal. J Epidemiol Community Health (1993) 2.17
HIV-associated nephropathy in transgenic mice expressing HIV-1 genes. Virology (1991) 2.16
The CD14 monocyte differentiation antigen maps to a region encoding growth factors and receptors. Science (1988) 2.16
Biochemical characterization of a second family of human Ia molecules, HLA-DS, equivalent to murine I-A subregion molecules. J Exp Med (1982) 2.15
Anticipation in Crohn's disease may be influenced by gender and ethnicity of the transmitting parent. Am J Gastroenterol (1998) 2.14
A standardized psychiatric assessment scale for rating chronic psychotic patients. Acta Psychiatr Scand (1977) 2.13
Current sickle cell screening program for newborns in New York City, 1979-1980. Am J Public Health (1983) 2.12
Nanoliter scale PCR with TaqMan detection. Nucleic Acids Res (1997) 2.11
The treatment of somatization: evaluation of a teaching package with general practice trainees. J Psychosom Res (1989) 2.10
Mental health care in the community: what should be on the agenda? Br J Gen Pract (1997) 2.09
Regulation by vitamin D metabolites of parathyroid hormone gene transcription in vivo in the rat. J Clin Invest (1986) 2.07
Long-term outcome analysis of two treatment methods for cleft palate: combined levator retropositioning and pharyngeal flap versus double-opposing Z-plasty. Cleft Palate Craniofac J (1999) 2.07
Randomised trial of impact of school mental-health programme in rural Rawalpindi, Pakistan. Lancet (1998) 2.04
Peptide binding specificity of HLA-DR4 molecules: correlation with rheumatoid arthritis association. J Exp Med (1995) 2.02
The state of hepatitis B and C in Europe: report from the hepatitis B and C summit conference*. J Viral Hepat (2011) 2.00
Outcomes of recognized and unrecognized depression in an international primary care study. Gen Hosp Psychiatry (1999) 2.00
The mouse homolog of the Gibbon ape leukemia virus receptor: genetic mapping and a possible receptor function in rodents. Virology (1991) 1.97
Prevalence of hepatitis C virus infection among injecting drug users in Glasgow 1990-1996: are current harm reduction strategies working? J Infect (2000) 1.94
T lymphocytes from healthy individuals with specificity to self-epitopes shared by the mycobacterial and human 65-kilodalton heat shock protein. J Immunol (1989) 1.94
Obsessive-compulsive disorder due to neuroacanthocytosis treated with citalopram. A case report. Pharmacopsychiatry (2006) 1.94
Regulation by vitamin D metabolites of messenger ribonucleic acid for preproparathyroid hormone in isolated bovine parathyroid cells. Proc Natl Acad Sci U S A (1985) 1.86
An international study of psychological problems in primary care. Preliminary report from the World Health Organization Collaborative Project on 'Psychological Problems in General Health Care'. Arch Gen Psychiatry (1993) 1.86
Triazolam as a substance of abuse among injecting drug users. Br J Addict (1992) 1.86
Psychiatric morbidity in general practice and the community. Psychol Med (1976) 1.81
Recent trends in HIV and other STIs in the United Kingdom: data to the end of 2002. Sex Transm Infect (2004) 1.79
Structural studies of murine I-E and human DR antigens. Mol Immunol (1979) 1.79
A syncytia assay for human immunodeficiency virus type I (HIV-I) envelope protein and its use in studying HIV-I mutations. Virology (1989) 1.78
The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish population. Am J Hum Genet (2002) 1.77
Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubation. Genes Immun (2004) 1.77
Single amino acid changes in DR and antigen define residues critical for peptide-MHC binding and T cell recognition. J Immunol (1991) 1.75
The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development. Development (2000) 1.74
Injury-induced proteoglycans inhibit the potential for laminin-mediated axon growth on astrocytic scars. Exp Neurol (1995) 1.73
Axonal guidance during development of the great cerebral commissures: descriptive and experimental studies, in vivo, on the role of preformed glial pathways. J Comp Neurol (1982) 1.73
Diet and the geographical distribution of multiple sclerosis. Lancet (1974) 1.72
Early childhood music education and predisposition to absolute pitch: teasing apart genes and environment. Am J Med Genet (2001) 1.71
Notable diversity in peptide composition of murine H-2K and H-2D alloantigens. Biochemistry (1974) 1.70
Murine Ia and human DR antigens: homology of amino-terminal sequences. Proc Natl Acad Sci U S A (1978) 1.70
T cell receptor V-segment frequencies in peripheral blood T cells correlate with human leukocyte antigen type. J Exp Med (1991) 1.69
Osteomalacia after prolonged glutethimide administration. Br Med J (1973) 1.67
Efficient trans-activation by the HIV-2 Tat protein requires a duplicated TAR RNA structure. Nucleic Acids Res (1990) 1.67
Peripheral blood gene expression profiling in rheumatoid arthritis. Genes Immun (2005) 1.66
Immunohistochemical analysis of human lymphomas with monoclonal antibodies to B cell and Ia antigens reactive in paraffin sections. Lab Invest (1985) 1.63
Structural polymorphism of human DR antigens. Nature (1979) 1.63
Structure and evolution of transplantation antigens: partial amino-acid sequences of H-2K and H-2D alloantigens. Proc Natl Acad Sci U S A (1976) 1.62
Determinants of somatization in primary care. Psychol Med (1991) 1.62
Commitment to X inactivation precedes the twinning event in monochorionic MZ twins. Am J Hum Genet (1998) 1.61
Guidance of optic axons in vivo by a preformed adhesive pathway on neuroepithelial endfeet. Dev Biol (1984) 1.59
A diffuse infiltrative CD8 lymphocytosis syndrome in human immunodeficiency virus (HIV) infection: a host immune response associated with HLA-DR5. Ann Intern Med (1990) 1.57
Biochemistry and expression of myelomonocytic antigens. J Immunol (1986) 1.56