Published in J Exp Med on February 01, 1978
Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus. Proc Natl Acad Sci U S A (1979) 14.61
Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains. J Exp Med (1978) 11.99
Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease. Proc Natl Acad Sci U S A (1981) 10.72
Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med (1994) 8.21
Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation. J Exp Med (1990) 4.46
Association of circulating retroviral gp70-anti-gp70 immune complexes with murine systemic lupus erythematosus. J Exp Med (1979) 2.86
Roles of interferon-gamma and interleukin-4 in murine lupus. J Clin Invest (1997) 2.04
Induction of lupus-associated autoantibodies in BALB/c mice by intraperitoneal injection of pristane. J Exp Med (1994) 2.02
Subclass restriction and polyclonality of the systemic lupus erythematosus marker antibody anti-Sm. J Clin Invest (1985) 1.62
A disease-related rheumatoid factor autoantibody is not tolerized in a normal mouse: implications for the origins of autoantibodies in autoimmune disease. J Exp Med (1996) 1.58
Murine lupus monoclonal antibodies define five epitopes on two different Sm polypeptides. Immunology (1986) 1.54
Stochastic control of anti-Sm autoantibodies in MRL/Mp-lpr/lpr mice. J Clin Invest (1987) 1.17
Mechanisms of autoantibody production in autoimmune MRL mice. J Exp Med (1980) 1.13
Parallel sets of autoantibodies in MRL-lpr/lpr mice. An anti-DNA, anti-SmRNP, anti-gp70 network. J Exp Med (1987) 1.08
Effect of an exogenous trigger on the pathogenesis of lupus in (NZB x NZW)F1 mice. Arthritis Rheum (2002) 1.06
Immune complexes in human diseases: a review. Am J Pathol (1980) 1.05
Distinctive immune response patterns of human and murine autoimmune sera to U1 small nuclear ribonucleoprotein C protein. J Clin Invest (1996) 1.01
Differential induction of lupus associated antinuclear antibodies in MRL mice by monoclonal anti-Sm antibodies. Clin Exp Immunol (1987) 1.00
Administration of monoclonal anti-Sm antibody prolongs the survival and renal function of MRL-lpr/lpr mice. Clin Exp Immunol (1986) 0.97
MRL/lpr mice produce anti-Ro 52,000 MW antibodies: detection, analysis of specificity and site of production. Immunology (1994) 0.96
Regulation of the anti-Sm autoantibody response in systemic lupus erythematosus mice by monoclonal anti-Sm antibodies. J Clin Invest (1990) 0.93
Individual variation of anti-Sm autoantibodies in the MRL/MP-lpr/lpr mouse: age-related increase in diversity. Clin Exp Immunol (1986) 0.92
A common idiotype expressed on a murine anti-Sm monoclonal antibody and antibodies in SLE sera. Clin Exp Immunol (1987) 0.91
Autoreactive MZ and B-1 B-cell activation by Faslpr is coincident with an increased frequency of apoptotic lymphocytes and a defect in macrophage clearance. Blood (2006) 0.90
Evidence for a naturally occurring anti-spermine antibody in normal rabbit serum. Proc Natl Acad Sci U S A (1980) 0.88
Anti-RNA polymerase I antibodies in sera of MRL lpr/lpr and MRL +/+ autoimmune mice. Correlation of antibody production with delayed onset of lupus-like disease in MRL +/+ mice. J Exp Med (1985) 0.87
(SWR x SJL)F1 mice: a new model of lupus-like disease. J Exp Med (1994) 0.85
Characterization and idiotypic analysis of an anti-RNP monoclonal antibody. Clin Exp Immunol (1984) 0.83
Effects of adjuvants for human use in systemic lupus erythematosus (SLE)-prone (New Zealand black/New Zealand white) F1 mice. Clin Exp Immunol (2014) 0.82
Relationship of age and sex to autoantibody expression in MRL-+/+ and MRL-lpr/lpr mice: demonstration of an association between the expression of antibodies to histones, denatured DNA and Sm in MRL-+/+ mice. Clin Exp Immunol (1988) 0.82
MRL/lpr-->severe combined immunodeficiency mouse allografts produce autoantibodies, acute graft-versus-host disease or a wasting syndrome depending on the source of cells. Clin Exp Immunol (1992) 0.82
Immunization with the Sm nuclear antigen induces anti-Sm antibodies in normal and MRL mice. Immunology (1988) 0.81
Serological and histological characterization of the new mutant strain of lpr mice, CBA/KlJms-lprcg/lprcg. Clin Exp Immunol (1990) 0.81
Autoantibodies produced spontaneously by young 1pr mice carry transforming growth factor beta and suppress cytotoxic T lymphocyte responses. J Exp Med (1995) 0.81
Characterization and specificity of B-cell responses in lupus induced by Mycobacterium bovis in NOD/Lt mice. Immunology (1998) 0.81
The role of microparticles in the generation of immune complexes in murine lupus. Clin Immunol (2012) 0.81
The snRNP core protein SmB and tissue-specific SmN protein are differentially distributed between snRNP particles. Nucleic Acids Res (1993) 0.80
Tamoxifen alleviates disease severity and decreases double negative T cells in autoimmune MRL-lpr/lpr mice. Immunology (2000) 0.80
Anti-nRNP anti-nuclear antibody-secreting cells are represented in the B-lymphocyte repertoire of normal and MRL/MP-lpr/lpr lupus mice. Immunology (1988) 0.80
Complement activation by antibodies to Sm in systemic lupus erythematosus. Clin Exp Immunol (1983) 0.79
Murine monoclonal antibodies to DNA. A comparison of MRL/lpr NZB/W and chronically graft-versus-host-diseased mice. Clin Exp Immunol (1990) 0.78
Fine specificities of anti-nuclear antibodies in murine models of graft-versus-host disease. Clin Exp Immunol (1990) 0.78
Further characterization of the autoantibody response of Palmerston North mice. J Clin Immunol (1999) 0.78
The transmembrane form of TNF-alpha drives autoantibody production in the absence of CD154: studies using MRL/Mp-Fas(lpr) mice. Clin Exp Immunol (2002) 0.78
Treatment of autoimmune MRL/Mp-lpr/lpr mice with cholera toxin. Clin Exp Immunol (1987) 0.75
Characterization of anti-P monoclonal antibodies directed against the ribosomal protein-RNA complex antigen and produced using Murphy Roths large autoimmune-prone mice. Clin Exp Immunol (2015) 0.75
Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice. PLoS One (2017) 0.75
Lupus autoantibodies discriminate between the highly homologous Sm polypeptides B/B' and SmN by binding an epitope restricted to B/B'. Clin Exp Immunol (1993) 0.75
Accelerated expression of anti-Sm and Y2 idiotype differ in dependence on T cell subsets in MRL/+ mice. Clin Exp Immunol (1990) 0.75
The immunology and pathology of NZB mice. Adv Immunol (1968) 9.04
Characteristics of a soluble nuclear antigen precipitating with sera of patients with systemic lupus erythematosus. J Immunol (1966) 7.40
Identification of antibodies to nuclear acidic antigens by counterimmunoelectrophoresis. Arthritis Rheum (1976) 5.33
Profiles of antinuclear antibodies in systemic rheumatic diseases. Ann Intern Med (1975) 5.00
Antibodies to cellular antigens in Sjögren's syndrome. J Clin Invest (1975) 4.62
Differentiation and characterization of autoantibodies and their antigens in Sjögren's syndrome. Arthritis Rheum (1976) 4.02
The pathogenesis of autoimmunity in New Zealand black mice. Curr Top Microbiol Immunol (1974) 3.98
The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum (1982) 67.54
A method of trace iodination of proteins for immunologic studies. Int Arch Allergy Appl Immunol (1966) 43.66
Antibodies reacting with ribosomal ribonucleoprotein in connective tissue diseases. Arthritis Rheum (1979) 13.72
Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains. J Exp Med (1978) 11.99
Mixed connective tissue disease--an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA). Am J Med (1972) 11.51
Murine models of systemic lupus erythematosus. Adv Immunol (1985) 9.79
Autoantibodies to nuclear antigens (ANA): their immunobiology and medicine. Adv Immunol (1982) 9.73
Pathogenesis of the glomerulonephritis of NZB/W mice. J Exp Med (1968) 8.91
Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus. J Clin Invest (1966) 8.64
The Raji cell radioimmune assay for detecting immune complexes in human sera. J Clin Invest (1976) 8.06
Characteristics of a soluble nuclear antigen precipitating with sera of patients with systemic lupus erythematosus. J Immunol (1966) 7.40
Autoantibody to centromere (kinetochore) in scleroderma sera. Proc Natl Acad Sci U S A (1980) 7.33
Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu Rev Immunol (1991) 6.89
The role of anti-glomerular basement membrane antibody in the pathogenesis of human glomerulonephritis. J Exp Med (1967) 6.81
Pathogenesis of chronic disease associated with persistent lymphocytic choriomeningitis viral infection. I. Relationship of antibody production to disease in neonatally infected mice. J Exp Med (1969) 6.03
Deoxyribonucleic acid antibody: a method to detect its primary interaction with deoxyribonucleic acid. Science (1968) 5.88
Identification of antibodies to nuclear acidic antigens by counterimmunoelectrophoresis. Arthritis Rheum (1976) 5.33
Profiles of antinuclear antibodies in systemic rheumatic diseases. Ann Intern Med (1975) 5.00
Autologous immune complex nephritis induced with renal tubular antigen. I. Identification and isolation of the pathogenetic antigen. J Exp Med (1968) 4.79
Antibodies to cellular antigens in Sjögren's syndrome. J Clin Invest (1975) 4.62
Etiopathogenesis of murine SLE. Immunol Rev (1981) 4.39
Autoantibody to a nuclear antigen in proliferating cells. J Immunol (1978) 4.36
Shwartzman reaction after human renal homotransplantation. N Engl J Med (1968) 4.05
Differentiation and characterization of autoantibodies and their antigens in Sjögren's syndrome. Arthritis Rheum (1976) 4.02
Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80-coilin. J Exp Med (1991) 4.02
Lymphocytic choriomeningitis: production of antibody by "tolerant" infected mice. Science (1967) 4.01
Autologous immune-complex pathogenesis of experimental allergic glomerulonephritis. Science (1967) 3.96
Diversity of antinuclear antibodies in progressive systemic sclerosis. Anti-centromere antibody and its relationship to CREST syndrome. Arthritis Rheum (1980) 3.87
Experimental glomerulonephritis: immunological events and pathogenetic mechanisms. Adv Immunol (1967) 3.83
Increased spontaneous polyclonal activation of B lymphocytes in mice with spontaneous autoimmune disease. J Immunol (1978) 3.78
Serum transfer of collagen-induced arthritis in mice. J Exp Med (1983) 3.74
The pathogenesis of glomerulonephritis. Am J Med (1968) 3.61
Purification and partial characterization of a nucleolar scleroderma antigen (Mr = 34,000; pI, 8.5) rich in NG,NG-dimethylarginine. J Biol Chem (1985) 3.60
Endogenous oncornaviral gene expression in adult and fetal mice: quantitative, histologic, and physiologic studies of the major viral glycorprotein, gp70. J Exp Med (1976) 3.51
Immunological and ultrastructural studies of the nuclear coiled body with autoimmune antibodies. Exp Cell Res (1991) 3.44
Autologous immune complex nephritis induced with renal tubular antigen. II. The pathogenetic mechanism. J Exp Med (1968) 3.40
The effect of passively administered antibody on antibody synthesis. J Exp Med (1967) 3.31
Analysis of T cell function in autoimmune murine strains. Defects in production and responsiveness to interleukin 2. J Exp Med (1981) 3.27
Anti-glomerular basement membrane antibody-induced glomerulonephritis. Kidney Int (1973) 3.09
Monoclonal autoantibody from a (New Zealand black x New Zealand white)F1 mouse and some human scleroderma sera target an Mr 34,000 nucleolar protein of the U3 RNP particle. Arthritis Rheum (1987) 3.09
The biology and detection of immune complexes. Adv Immunol (1979) 3.05
Identification of a nuclear protein (Scl-70) as a unique target of human antinuclear antibodies in scleroderma. J Biol Chem (1979) 2.99
A 52-kD protein is a novel component of the SS-A/Ro antigenic particle. J Exp Med (1988) 2.98
IgM rheumatoid factors in mice injected with bacterial lipopolysaccharides. J Immunol (1979) 2.86
Association of circulating retroviral gp70-anti-gp70 immune complexes with murine systemic lupus erythematosus. J Exp Med (1979) 2.86
A nuclear antigen associated with cell proliferation and blast transformation. J Exp Med (1981) 2.82
A spontaneous rheumatoid arthritis-like disease in MRL/l mice. J Exp Med (1982) 2.76
Expression of proliferating cell nuclear antigen (PCNA)/cyclin during the cell cycle. Exp Cell Res (1986) 2.74
Relationship of nuclear staining patterns with precipitating antibodies in systemic lupus erythematosus. J Lab Clin Med (1967) 2.71
Autoantibodies in the diagnosis of systemic rheumatic diseases. Semin Arthritis Rheum (1995) 2.67
The potential pathogenic role of complement in dengue hemorrhagic shock syndrome. N Engl J Med (1973) 2.64
Mechanism and modification of rejection of heterografts between divergent species. Transplant Proc (1970) 2.63
Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes. J Exp Med (1979) 2.55
The antibody response of mice to murine leukemia virus in spontaneous infection: absence of classical immunologic tolerance (AKR mice-complement-fixing antibodies-lymphocytic choriomeningitis virus-immunofluorescence-glomerular deposits of antigen-antibody complexes). Proc Natl Acad Sci U S A (1972) 2.54
Lymphocytes transformed by Epstein-Barr virus. Induction of nuclear antigen reactive with antibody in rheumatoid arthritis. J Exp Med (1978) 2.52
Binding of soluble immune complexes to human lymphoblastoid cells. II. Use of Raji cells to detect circulating immune complexes in animal and human sera. J Exp Med (1974) 2.51
Transfer of ovine experimental allergic glomerulonephritis (EAG) with serum. J Exp Med (1966) 2.42
Relationship of acetyl transferase activity to antinuclear antibodies and toxic symptoms in hypertensive patients treated with hydralazine. J Lab Clin Med (1970) 2.41
Histocompatibility-linked genetic control of disease susceptibility. Murine lymphocytic choriomeningitis virus infection. J Exp Med (1973) 2.39
Humoral antibodies and coagulation mechanisms in the accelerated or hyperacute rejection of renal homografts in sensitized canine recipients. Surgery (1970) 2.38
The oncornavirus glycoprotein gp69/71: a constituent of the surface of normal and malignant thymocytes. J Exp Med (1975) 2.37
A novel cytoplasmic protein with RNA-binding motifs is an autoantigen in human hepatocellular carcinoma. J Exp Med (1999) 2.36
Clotting changes, including disseminated intravascular coagulation, during rapid renal-homograft rejection. N Engl J Med (1970) 2.33
Association of antinuclear and antinucleolar antibodies in progressive systemic sclerosis. Clin Exp Immunol (1982) 2.29
Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen. J Clin Invest (1991) 2.28
Antinucleolar antibodies in human sera. J Immunol (1973) 2.28
Characterization and isolation of specific renal tubular epithelial antigens. J Immunol (1967) 2.25
Binding of soluble immune complexes to human lymphoblastoid cells. I. Characterization of receptors for IgG Fc and complement and description of the binding mechanism. J Exp Med (1974) 2.22
Association between the nucleolus and the coiled body. J Struct Biol (1991) 2.18
The effect of induced chronic viral infections on the immunologic diseases of New Zealand mice. J Exp Med (1970) 2.16
Identification of a B cell differentiation factor(s) spontaneously produced by proliferating T cells in murine lupus strains of the lpr/lpr genotype. J Exp Med (1983) 2.15
Monoclonal antibodies to a nuclear protein (PCNA/cyclin) associated with DNA replication. Exp Cell Res (1987) 2.13
Immunocytochemical analysis of the coiled body in the cell cycle and during cell proliferation. Proc Natl Acad Sci U S A (1993) 2.13
Immunopathogenicity and oncogenicity of murine leukemia viruses. I. Induction of immunologic disease and lymphoma in (BALB-c times NZB)F1 mice by Scripps leukemia virus. J Exp Med (1974) 2.12
Immunohistochemical study of allergic encephalomyelitis. Am J Pathol (1968) 2.10
Evidence for a subset of rheumatoid factors that cross-react with DNA-histone and have a distinct cross-idiotype. J Exp Med (1980) 2.10
Pathogenesis of the slow disease of the central nervous system associated with WM 1504 E virus. I. Relationship of strain susceptibility and replication to disease. Am J Pathol (1977) 2.08
Influence of thymic genotype on the systemic lupus erythematosus-like disease and T cell proliferation of MRL/Mp-lpr/lpr mice. J Exp Med (1981) 2.07
An immunofluorescent study of the skin lesions in systemic lupus erythematosus. Arthritis Rheum (1966) 2.07
Diagnosis of immunopathologic renal disease. Kidney Int (1974) 2.07
Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice. J Exp Med (1980) 2.07
Monoclonal antibodies to proliferating cell nuclear antigen (PCNA)/cyclin as probes for proliferating cells by immunofluorescence microscopy and flow cytometry. J Immunol Methods (1988) 2.07
Induction of murine autoimmune disease by chronic polyclonal B cell activation. J Exp Med (1983) 2.06
Circulating immune complexes in infective endocarditis. N Engl J Med (1976) 2.02
Radioiodination of proteins by the use of the chloramine-T method. Methods Enzymol (1980) 2.01
Tissue injury in lymphocytic choriomeningitis viral infection: virus-induced immunologically specific release of a cytotoxic factor from immune lymphoid cells. Virology (1970) 2.00
Autoantibody to RNA polymerase I in scleroderma sera. J Clin Invest (1987) 1.99
An immunologic precipitin system between soluble nucleoprotein and serum antibody in systemic lupus erythematosus. J Clin Invest (1967) 1.99
Detection of a nucleolar 7-2 ribonucleoprotein and a cytoplasmic 8-2 ribonucleoprotein with autoantibodies from patients with scleroderma. J Biol Chem (1983) 1.98
Distribution of kinetochore (centromere) antigen in mammalian cell nuclei. J Cell Biol (1981) 1.97
Immune response to a hapten coupled to a nonimmunogenic carrier. Influence of lipopolysaccharide. J Exp Med (1972) 1.95
Antigen quantitation in experimental immune complex glomerulonephritis. I. Acute serum sickness. J Immunol (1970) 1.93
Serum antibody in rheumatoid arthritis reactive with a cell-associated antigen. Demonstration by precipitation and immunofluorescence. Arthritis Rheum (1976) 1.92
Isolation and characterization of nuclear ribonucleoprotein complexes using human anti-nuclear ribonucleoprotein antibodies. J Biol Chem (1979) 1.92