Published in Methods Enzymol on January 01, 1988
Hemopexin down-regulates LPS-induced proinflammatory cytokines from macrophages. J Leukoc Biol (2009) 2.45
Identification of a genetic locus of Haemophilus influenzae type b necessary for the binding and utilization of heme bound to human hemopexin. Proc Natl Acad Sci U S A (1992) 1.80
Bacterial heme-transport proteins and their heme-coordination modes. Arch Biochem Biophys (2008) 1.36
Identification of an outer membrane protein involved in utilization of hemoglobin-haptoglobin complexes by nontypeable Haemophilus influenzae. Infect Immun (1996) 1.16
Degradation of host heme proteins by lysine- and arginine-specific cysteine proteinases (gingipains) of Porphyromonas gingivalis. J Bacteriol (2001) 1.14
A precious metal: Iron, an essential nutrient for all cells. Genes Nutr (2006) 1.09
An alternative view of the proposed alternative activities of hemopexin. Protein Sci (2011) 0.88
Quantification of fucosylated hemopexin and complement factor H in plasma of patients with liver disease. Anal Chem (2014) 0.84
LC-MS3 quantification of O-glycopeptides in human serum. Electrophoresis (2013) 0.82
Roles of heme iron-coordinating histidine residues of human hemopexin expressed in baculovirus-infected insect cells. Proc Natl Acad Sci U S A (1994) 0.82
Hemopexin in severe inflammation and infection: mouse models and human diseases. Crit Care (2015) 0.78
Metal ions and electrolytes regulate the dissociation of heme from human hemopexin at physiological pH. J Biol Chem (2010) 0.76
An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors. Stem Cell Reports (2017) 0.75
Expression of haemopexin receptors by cultured human cytotrophoblast. Biochem J (1995) 0.75
Insulin attenuates TNFα-induced hemopexin mRNA: An anti-inflammatory action of insulin in rat H4IIE hepatoma cells. Biochem Biophys Rep (2017) 0.75
A gene cluster involved in the utilization of both free heme and heme:hemopexin by Haemophilus influenzae type b. J Bacteriol (1995) 2.08
A functional tonB gene is required for both utilization of heme and virulence expression by Haemophilus influenzae type b. Infect Immun (1994) 1.81
Plasma concentrations of hemopexin, haptoglobin and heme in patients with various hemolytic diseases. Blood (1968) 1.81
Identification of a genetic locus of Haemophilus influenzae type b necessary for the binding and utilization of heme bound to human hemopexin. Proc Natl Acad Sci U S A (1992) 1.80
Exposure of endothelial cells to free heme potentiates damage mediated by granulocytes and toxic oxygen species. Lab Invest (1991) 1.77
Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix. J Cell Physiol (1988) 1.76
Hemopexin. N Engl J Med (1970) 1.46
Resolution of two forms of cytochrome P-450 from liver microsomes of rabbit treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Biol Chem (1977) 1.41
Partial characterization of the heme-binding serum glycoproteins rabbit and human hemopexin. Biochemistry (1971) 1.26
Decreased liver cytochrome P-450 in rats caused by norethindrone or ethynyloestradiol. Biochem J (1977) 1.21
Pathophysiology of heme synthesis. Semin Hematol (1988) 1.19
Identification of an outer membrane protein involved in utilization of hemoglobin-haptoglobin complexes by nontypeable Haemophilus influenzae. Infect Immun (1996) 1.16
The influence of heme-binding proteins in heme-catalyzed oxidations. Arch Biochem Biophys (1988) 1.16
Hepatic subcellular metabolism of heme from heme-hemopexin: incorporation of iron into ferritin. Biochem Biophys Res Commun (1979) 1.16
Binding of porphyrins to rabbit hemopexin and albumin. J Biol Chem (1973) 1.13
Fluorimetric study of the binding of protoporphyrin to haemopexin and albumin. Biochem J (1981) 1.06
Plasma hemopexin homeostasis during the acute phase response. J Lab Clin Med (1972) 1.05
A protein of the Z class of liver cytosolic proteins in the rat that preferentially binds heme. J Biol Chem (1985) 1.04
Relationship of the biosynthesis of alpha-fetoprotein, albumin, hemopexin, and haptoglobin to the growth state of fetal rat hepatocyte cultures. Ann N Y Acad Sci (1975) 1.04
Identification of rabbit microsomal cytochrome P-450 isozyme, form 1, as a hepatic progesterone 21-hydroxylase. Biochem Biophys Res Commun (1982) 1.03
Studies on heme transfer from microsomal hemoproteins to heme-binding plasma proteins. Mol Pharmacol (1974) 1.03
Interaction of porphyrins with proteins. Semin Hematol (1977) 1.00
Rat hemopexin. Molecular cloning, primary structural characterization, and analysis of gene expression. Biochemistry (1991) 0.99
Sites of formation of the serum proteins transferrin and hemopexin. J Clin Invest (1973) 0.98
Kinetics of the interaction of hemin liposomes with heme binding proteins. Biochemistry (1984) 0.98
Quantitative determination of hemoglobin and cytochemical staining for peroxidase using 3,3',5,5'-tetramethylbenzidine dihydrochloride, a safe substitute for benzidine. Anal Biochem (1979) 0.97
Purification, characterization, and cloning of a heme-binding protein (23 kDa) in rat liver cytosol. Biochemistry (1995) 0.97
Synthesis of hemopexin and cysteine protease inhibitor is coordinately regulated by HSF-II and interferon-beta 2 in rat hepatoma cells. Biochem Biophys Res Commun (1987) 0.97
The aromatic and heme chromophores of rabbit hemopexin. Difference absorption and fluorescence spectra. Biochim Biophys Acta (1976) 0.94
Interactions of porphyrins with rabbit hemopexin. J Biol Chem (1972) 0.94
Identification of the major cytochrome P-450 form transplacentally induced in neonatal rabbits by 3,3,7,8-tetrachlorodibenzo-p-dioxin. J Biol Chem (1978) 0.94
Tissue localization of the heme-hemopexin complex in the rabbit and the rat as studied by light microscopy with the use of radioisotopes. J Lab Clin Med (1970) 0.94
Secretion of haem by hepatic parenchymal cells. Biochem J (1979) 0.93
Human and rabbit hemopexins: tryptic peptides and N-terminal sequences. FEBS Lett (1974) 0.93
The rat and human hemopexin genes contain an identical interleukin-6 response element that is not a target of CAAT enhancer-binding protein isoforms. J Biol Chem (1994) 0.92
The rat heme oxygenase-1 gene is transcriptionally induced via the protein kinase A signaling pathway in rat hepatocyte cultures. Mol Pharmacol (1998) 0.91
Expression of the mRNA of heme-binding protein 23 is coordinated with that of heme oxygenase-1 by heme and heavy metals in primary rat hepatocytes and hepatoma cells. Biochemistry (1995) 0.91
Hemopexin metabolism in sickle-cell disease, porphyrias and control subjects--effects of heme injection. N Engl J Med (1974) 0.91
Concepts of heme distribution within hepatocytes. Biochem Pharmacol (1985) 0.90
The type II hemopexin interleukin-6 response element predominates the transcriptional regulation of the hemopexin acute phase responsiveness. Biochem Biophys Res Commun (1995) 0.90
Plasma hemopexin levels following aortic valve replacement: a valuable screening test for assessing the severity of cardiac hemolysis. J Lab Clin Med (1972) 0.89
Effect of serum proteins on haem uptake and metabolism in primary cultures of liver cells. Biochem J (1988) 0.89
Rabbit hepatic progesterone 21-hydroxylase exhibits a bimodal distribution of activity. Science (1982) 0.89
Hemopexin metabolism in patients with altered serum levels. J Lab Clin Med (1983) 0.88
Removal of heme from cytochrome P-450CAM by hemopexin and apomyoglobin associated with loss of P-450 hydroxylase activity. Biochem Biophys Res Commun (1969) 0.88
Hemin binding to serum proteins and the catalysis of interprotein transfer. Biochemistry (1983) 0.87
Studies on the disposal of intravascular heme in the rabbit. J Lab Clin Med (1969) 0.87
Interaction of hemopexin, albumin and liver fatty acid-binding protein with protoporphyrin. Hepatology (1989) 0.87
Influence of transcriptional regulation and mRNA stability on hemopexin gene expression in regenerating liver. Arch Biochem Biophys (1994) 0.86
A radioimmunoassay employing polyethylene glycol (PEG) for measuring dilute concentrations of rat hemopexin, albumin and haptoglobin. Immunochemistry (1975) 0.86
The role of cytosolic proteins in the intracellular transport of haem in rat liver. A dual-label approach. Biochem J (1982) 0.85
Catabolism of photo-oxidized and desialylated hemopexin in the rabbit. J Biol Chem (1975) 0.85
Properties of liver mitochondria from iron-loaded rats. Biochem Biophys Res Commun (1975) 0.85
Purification and partial characterization of human hemopexin. J Lab Clin Med (1967) 0.85
Identification of a liver preference enhancer element of the rat hemopexin gene and its interaction with nuclear factors. J Biol Chem (1994) 0.85
Interaction of rabbit hemopexin with rose bengal and photooxidation of the rose bengal-hemopexin complex. J Biol Chem (1975) 0.84
Effect of porphyrinogenic agents on protein synthesis and bilirubin formation by the isolated perfused rat liver. Biochim Biophys Acta (1977) 0.84
Heme complexes of rabbit hemopexin, human hemopexin and human serum albumin: electron spin resonance and Mssbauer spectroscopic studies. Biochem Biophys Res Commun (1974) 0.83
Effects of hexachlorobenzene and iron loading on rat liver mitochondria. Biochim Biophys Acta (1981) 0.83
Protein-mediated efflux of heme from isolated rat liver mitochondria. Biochem Biophys Res Commun (1990) 0.83
Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin and phenobarbital on the occurrence and distribution of four cytochrome P-450 isozymes in rabbit kidney, lung, and liver. Cancer Res (1982) 0.83
In vivo fate of hemopexin and heme-hemopexin complexes in the rat. Arch Biochem Biophys (1993) 0.83
Molecular cloning of a mammalian hyaluronidase reveals identity with hemopexin, a serum heme-binding protein. J Biol Chem (1994) 0.82
Hepatic heme and drug metabolism in rats with chronic mountain sickness. Am J Physiol (1986) 0.82
The effect in vivo and in vitro of allylisopropylacetamide on the content of hepatic microsomal cytochrome P-450 2 of phenobarbital treated rabbits. Biochem Biophys Res Commun (1983) 0.82
Cellular and subcellular localization of heme and hemopexin in the rabbit. Acta Haematol (1975) 0.82
Roles of heme iron-coordinating histidine residues of human hemopexin expressed in baculovirus-infected insect cells. Proc Natl Acad Sci U S A (1994) 0.82
Studies on the induction of serum hemopexin by pentobarbital and polycyclic hydrocarbons. Biochem Pharmacol (1972) 0.81
Hemopexin synthesis in vitro by human fetal tissues. Pediatr Res (1975) 0.81
Effects of haem infusion on biliary secretion of porphyrins, haem and bilirubin in man. Eur J Clin Invest (1982) 0.81
Gene regulation of HBP 23 by metalloporphyrins and protoporphyrin IX in liver and hepatocyte cultures. Biochem Biophys Res Commun (1997) 0.81
Specificity in the activation and inhibition by flavonoids of benzo[a]pyrene hydroxylation by cytochrome P-450 isozymes from rabbit liver microsomes. J Biol Chem (1981) 0.81
Long-term intercalation of residual hemin in erythrocyte membranes distorts the cell. Biochim Biophys Acta (1991) 0.81
Hemopexin is a developmentally regulated, acute-phase plasma protein in the chicken. J Biol Chem (1986) 0.81
Catalysis of divergent pathways of 2-acetylaminofluorene metabolism by multiple forms of cytochrome P-450. Cancer Res (1980) 0.80
Pharmacologic induction of serum hemopexin by 3-methylcolanthrene and allylisopropylacetamide. J Lab Clin Med (1970) 0.80
Hyaluronan-binding properties of human serum hemopexin. FEBS Lett (1996) 0.80
Plasma clearance of 125I-labelled haemopexin in normal and haem-loaded rabbits. Br J Haematol (1973) 0.80
An avian serum alpha 1-glycoprotein, hemopexin, differing significantly in both amino acid and carbohydrate composition from mammalian (beta-glycoprotein) counterparts. Biochemistry (1986) 0.80
Effect of heme on allylisopropylacetamide-induced changes in heme and drug metabolism in the rhesus monkey (Macaca mulatta). Biochem Pharmacol (1983) 0.80
Modulation of hemopexin gene expression by physiological oxygen tensions in primary rat hepatocyte cultures. Biochem Biophys Res Commun (1995) 0.80
Kinetics of hemoprotein reduction and interprotein heme transfer. Biochemistry (1985) 0.80
Multiple forms of cytochrome P-450: resolution and purification of rabbit liver aryl hydrocarbon hydroxylase. Biochem Biophys Res Commun (1977) 0.80
The role of cytochrome P-450 forms in 2-aminoanthracene and benz[alpha]pyrene mutagenesis. Biochem Biophys Res Commun (1979) 0.79
Heterogeneous distribution of drug metabolism in elutriated rat hepatocytes. Biochem Pharmacol (1985) 0.79
Decreased cytochrome P450 and increased prophyrin concentrations in the livers of rats on a low iron diet given a single dose of desferrioxamine. Biochem Pharmacol (1978) 0.79
Differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin of multiple forms of rabbit microsomal cytochrome P-450: evidence for tissue specificity. Mol Pharmacol (1980) 0.79
Griseofulvin causing hyperhemopexinemia and hepatic proliferation in mice: an in vivo and in vitro study. J Invest Dermatol (1977) 0.79
Hemopexin metabolism in the rabbit. J Lab Clin Med (1972) 0.79
Protective role of hemopexin on heme-dependent lung oxidative stress. Biochem Biophys Res Commun (1993) 0.79
Proton NMR study of the heme complex of hemopexin. Biochim Biophys Acta (1994) 0.79
A comparison of hepatocyte size distribution in untreated and phenobarbital-treated rats as assessed by flow cytometry. Dig Dis Sci (1984) 0.78
Plasma levels of hemopexin and albumin in disorders of porphyrin metabolism. Proc Soc Exp Biol Med (1974) 0.78
Do heme and bilirubin have identical binding sites on the albumin molecule? Biochem Biophys Res Commun (1971) 0.78
Synthesis of hemopexin with and without hormonal supplementation in rat hepatocyte suspensions: comparison with that of albumin and of fibrinogen. Can J Biochem (1976) 0.78
Interaction of rabbit hemopexin with bilirubin. Biochim Biophys Acta (1978) 0.78
Effect of hemoglobin and hematin on plasma clearance of hemopexin, photo-inactivated hemopexin and albumin (38575). Proc Soc Exp Biol Med (1975) 0.78
Initial heme uptake from albumin by short-term cultured rat hepatocytes is mediated by a transport mechanism differing from that of other organic anions. Hepatology (1998) 0.78
Removal of exogenous haem or haemoglobin from rat liver microsomes. Anal Biochem (1978) 0.78