Effect of Electroencephalography-Guided Anesthetic Administration on Postoperative Delirium Among Older Adults Undergoing Major Surgery: The ENGAGES Randomized Clinical Trial.

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🔗 View Article (PMID 30721296)

Published in JAMA on February 22, 2019

Authors

Troy S Wildes¹, Angela M Mickle¹, Arbi Ben Abdallah¹, Hannah R Maybrier¹, Jordan Oberhaus¹, Thaddeus P Budelier¹, Alex Kronzer¹, Sherry L McKinnon¹, Daniel Park¹, Brian A Torres¹, Thomas J Graetz¹, Daniel A Emmert¹, Ben J Palanca¹, Shreya Goswami¹, Katherine Jordan¹, Nan Lin², Bradley A Fritz¹, Tracey W Stevens¹, Eric Jacobsohn³, Eva M Schmitt⁴, Sharon K Inouye⁴, Susan Stark⁵, Eric J Lenze⁶, Michael S Avidan¹, ENGAGES Research Group

Author Affiliations

1: Department of Anesthesiology, Washington University School of Medicine, St Louis, Missouri.
2: Department of Mathematics, Washington University School of Medicine, St Louis, Missouri.
3: Department of Anesthesiology, University of Manitoba, Winnipeg, Canada.
4: Department of Medicine, Beth Israel-Deaconess Medical Center, Hebrew Senior Life, Harvard Medical School, Boston, Massachusetts.
5: Department of Occupational Therapy, Washington University School of Medicine, St Louis, Missouri.
6: Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri.

Associated clinical trials:

Electroencephalography Guidance of Anesthesia (ENGAGES) | NCT02241655

The PATHFINDER Study: A Feasibility Trial (PATHFINDER) | NCT04016740

Intraoperative EEG Monitoring and Postoperative Delirium in Elderly Patients With Sevoflurane Anesthesia | NCT04292561

Articles citing this ↘

Electroencephalography-guided anaesthetic administration does not impact postoperative delirium among older adults undergoing major surgery: an independent discussion of the ENGAGES trial. Br J Anaesth (2019) 1.37

Electroencephalography-Guided Anesthetic Administration and Postoperative Delirium. JAMA (2019) 0.98

Electroencephalography-Guided Anesthetic Administration and Postoperative Delirium. JAMA (2019) 0.97

Electroencephalography-Guided Anesthetic Administration and Postoperative Delirium. JAMA (2019) 0.95

Depth of Anesthesia and Postoperative Delirium. JAMA (2019) 0.75

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