Effect of Electroencephalography-Guided Anesthetic Administration on Postoperative Delirium Among Older Adults Undergoing Major Surgery: The ENGAGES Randomized Clinical Trial.

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🔗 View Article (PMID 30721296)

Published in JAMA on February 22, 2019

Authors

Troy S Wildes1, Angela M Mickle1, Arbi Ben Abdallah1, Hannah R Maybrier1, Jordan Oberhaus1, Thaddeus P Budelier1, Alex Kronzer1, Sherry L McKinnon1, Daniel Park1, Brian A Torres1, Thomas J Graetz1, Daniel A Emmert1, Ben J Palanca1, Shreya Goswami1, Katherine Jordan1, Nan Lin2, Bradley A Fritz1, Tracey W Stevens1, Eric Jacobsohn3, Eva M Schmitt4, Sharon K Inouye4, Susan Stark5, Eric J Lenze6, Michael S Avidan1, ENGAGES Research Group

Author Affiliations

1: Department of Anesthesiology, Washington University School of Medicine, St Louis, Missouri.
2: Department of Mathematics, Washington University School of Medicine, St Louis, Missouri.
3: Department of Anesthesiology, University of Manitoba, Winnipeg, Canada.
4: Department of Medicine, Beth Israel-Deaconess Medical Center, Hebrew Senior Life, Harvard Medical School, Boston, Massachusetts.
5: Department of Occupational Therapy, Washington University School of Medicine, St Louis, Missouri.
6: Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri.

Associated clinical trials:

Electroencephalography Guidance of Anesthesia (ENGAGES) | NCT02241655

The PATHFINDER Study: A Feasibility Trial (PATHFINDER) | NCT04016740

Intraoperative EEG Monitoring and Postoperative Delirium in Elderly Patients With Sevoflurane Anesthesia | NCT04292561