Published in J Exp Med on November 01, 1978
Distinct functional phenotypes of cloned Ia-restricted helper T cells. J Exp Med (1985) 2.39
Fine specificity of regulatory T cells. II. Suppressor and helper T cells are induced by different regions of hen egg-white lysozyme in a genetically nonresponder mouse strain. J Exp Med (1979) 2.12
Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. V. Role of idiotypes in the suppressor pathway. J Exp Med (1980) 2.11
Mice whose B cells cannot produce the T15 idiotype also lack an antigen-specific helper T cell required for T15 expression. J Exp Med (1979) 1.86
Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. VIII. Suppressor cell pathways in cutaneous sensitivity responses. J Exp Med (1981) 1.80
Antigen- and receptor-driven regulatory mechanisms. I. Induction of suppressor T cells with anti-idiotypic antibodies. J Exp Med (1979) 1.62
Suppression of idiotype and generation of suppressor T cells with idiotype-conjugated thymocytes. J Exp Med (1979) 1.56
Selective suppression of the major idiotypic component of an antihapten response by soluble T cell-derived factors with idiotypic or anti-idiotypic receptors. J Exp Med (1980) 1.47
Antigen- and receptor-driven regulatory mechanisms. II. Induction of suppressor T cells with idiotype-coupled syngeneic spleen cells. J Exp Med (1979) 1.42
Suppression of hapten-specific delayed-type hypersensitivity responses in mice by idiotype-specific suppressor T cells after administration of anti-idiotypic antibodies. J Exp Med (1979) 1.26
Induction of idiotype-bearing, nuclease-specific helper T cells by in vivo treatment with anti-idiotype. J Exp Med (1981) 1.18
Subpopulations of B cells distinguished by cell surface expression of Ia antigens. Correlation of Ia and idiotype during activation by cloned Ia-restricted T cells. J Exp Med (1983) 1.13
Idiotype profile of an immune response. I. Contrasts in idiotypic dominance between primary and secondary responses and between IgM and IgG plaque-forming cells. J Exp Med (1981) 1.10
Mechanisms of idiotype suppression. I. In vitro generation of idiotype-specific suppressor T cells by anti-idiotype antibodies and specific antigen. J Exp Med (1979) 1.04
Autoregulation of immune responses via idiotype network interactions. Microbiol Rev (1980) 1.01
An idiotype-specific helper population that bears immunoglobulin, Ia, and Lyt-1 determinants. J Exp Med (1984) 0.99
Suppression of interstitial nephritis by auto-anti-idiotypic immunity. J Exp Med (1982) 0.98
Preparation and characterization of the anti-idiotypic properties of rabbit anti-timothy antigen B helper factor and anti-mouse timothy IgE antisera. Immunology (1982) 0.95
Late clonal selection and expansion of the TEPC-15 germ-line specificity. J Exp Med (1980) 0.92
Balb/c T cells have the potential to recognize the TEPC 15 prototype antibody and its somatic variants. J Exp Med (1981) 0.92
Antigen-specific helper T cells required for dominant production of an idiotype (THId) are not under immune response (Ir) gene control. J Exp Med (1980) 0.90
Generation of idiotype-specific T cell help through network perturbation. J Exp Med (1981) 0.88
Idiotypic self binding of a dominant germline idiotype (T15). Autobody activity is affected by antibody valency. J Exp Med (1987) 0.88
Restricted adult clonal profiles induced by neonatal immunization. Influence of suppressor T cells. J Exp Med (1983) 0.87
Microheterogeneity in regulatory circuits for T-cell alloresponsiveness. Immunology (1981) 0.82
Antiidiotypes against anti-H-2 monoclonal antibodies. V. In vivo antiidiotype treatment induces idiotype-specific helper T cells. J Exp Med (1983) 0.82
Antigen-specific helper T cells required for dominant idiotype expression are not H-2 restricted. J Exp Med (1981) 0.81
Tolerance for self IG at the level of the Ly1+ T cell. J Exp Med (1983) 0.78
Two Ly-2 T helper cell subsets distinguished by Qa-1 phenotype. The priming environment determines whether one or both subsets will be generated. J Exp Med (1982) 0.77
The assessment of anti-idiopathic antibodies as effective immunoregulatory probes in vivo. Clin Exp Immunol (1982) 0.77
Immunoregulatory effects of covalent antigen-antibody complexes. IV. Priming and tolerance in T-dependent responses. Immunology (1982) 0.77
Regulation by complementary idiotypes. Ig protects the clone producing it. J Exp Med (1981) 0.77
A rapid method for the isolation of functional thymus-derived murine lymphocytes. Eur J Immunol (1973) 45.44
Antitrinitrophenyl (TNP) plaque assay. Primary response of Balb/c mice to soluble and particulate immunogen. Proc Soc Exp Biol Med (1969) 18.89
Plaque formation in agar by single antibody-producing cells. Science (1963) 17.94
Use of erythrocytes sensitized with purified pneumococcal polysaccharides for the assay of antibody and antibody-producing cells. Appl Microbiol (1969) 5.29
T-cell regulation of antibody responses: demonstration of allotype-specific helper T cells and their specific removal by suppressor T cells. J Exp Med (1976) 5.11
Affinity labeling of a phosphorylcholine binding mouse myeloma protein. Biochemistry (1972) 4.26
Genetics of a new IgVH (T15 idiotype) marker in the mouse regulating natural antibody to phosphorylcholine. J Exp Med (1974) 3.64
Inheritance of an idiotype associated with the immune response of inbred mice to phosphorylcholine. Eur J Immunol (1972) 3.04
Different Ly antigen phenotypes of in vitro induced helper and suppressor cells. Nature (1975) 2.91
Specific inhibition of plaque formation to phosphorylcholine by antibody against antibody. Science (1972) 2.73
Idiotype suppression. II. Amplification of a suppressor T cell with anti-idiotypic activity. Eur J Immunol (1975) 2.59
Idiotypes as variable region markers: analogies between receptors on phosphorylcholine-specific T and B lymphocytes. Immunol Rev (1977) 2.54
Clonal nature of the immune response to phosphorylcholine. II. Idiotypic specificity and binding characteristics of anti-phosphorylcholine antibodies. J Immunol (1974) 1.95
Heterogeneity of the BALB/c antiphosphorylcholine antibody response at the precursor cell level. J Exp Med (1975) 1.75
Neonatal tolerance induced by antibody against antigen-specific receptor. Science (1974) 1.61
Immunological suppression of idiotypic specificities. Transplant Rev (1975) 1.55
Separation of helper and suppressor T lymphocytes. II. Ly phenotypes and lack of DNA synthesis requirement for the generation of concanavalin A helper and suppressor cells. J Exp Med (1977) 1.39
Expression of new idiotypes following neonatal idiotypic suppression of a dominant clone. Eur J Immunol (1976) 1.23
Anti-receptor antibody. II. Induction of long-term unresponsiveness in neonatal mice. J Immunol (1975) 1.19
A requirement for two cell types for antibody formation in vitro. Science (1967) 8.91
Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches. Annu Rev Immunol (1997) 5.95
Control of mating preferences in mice by genes in the major histocompatibility complex. J Exp Med (1976) 5.52
A functional dichotomy in CD4+ T lymphocytes. Immunol Today (1988) 4.18
Risk factors for perinatal transmission of human immunodeficiency virus type 1 in women treated with zidovudine. Pediatric AIDS Clinical Trials Group Study 185 Team. N Engl J Med (1999) 4.12
Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells. J Exp Med (1995) 3.98
Signals and signs for lymphocyte responses. Cell (1994) 3.66
Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene. J Biol Chem (1997) 3.66
Cell interactions in the primary immune response in vitro: a requirement for specific cell clusters. J Exp Med (1969) 3.38
Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production. J Exp Med (1997) 3.33
Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors. Science (1999) 3.10
Murine epidermal cell-derived thymocyte-activating factor resembles murine interleukin 1. J Immunol (1982) 2.90
Retroviral induction of acute lymphoproliferative disease and profound immunosuppression in adult C57BL/6 mice. J Exp Med (1985) 2.87
Activation of mouse lymphocytes by anti-immunoglobulin. I. Parameters of the proliferative response. J Exp Med (1978) 2.86
Early T lymphocytes. Differentiation in vivo of adult intrathymic precursor cells. J Exp Med (1985) 2.81
Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo. J Exp Med (1995) 2.80
Neutralizing antibodies have limited effects on the control of established HIV-1 infection in vivo. Immunity (1999) 2.67
Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirus. Nature (1986) 2.64
Cloned, Ia-restricted T cells that do not produce interleukin 4(IL 4)/B cell stimulatory factor 1(BSF-1) fail to help antigen-specific B cells. J Immunol (1987) 2.53
Surface immunoglobulin D as a functional receptor for a subclass of B lymphocytes. Immunol Rev (1977) 2.50
Ontogeny of mouse lymphocyte function. II. Development of the ability to produce antibody is modulated by T lymphocytes. J Exp Med (1975) 2.49
Distinct functional phenotypes of cloned Ia-restricted helper T cells. J Exp Med (1985) 2.39
Antigen-specific activation of effector macrophages by IFN-gamma producing (TH1) T cell clones. Failure of IL-4-producing (TH2) T cell clones to activate effector function in macrophages. J Immunol (1989) 2.32
An Lyt differentiated thymocyte subpopulation detected by flow microfluorometry. Nature (1979) 2.29
B lymphocytes can be competent antigen-presenting cells for priming CD4+ T cells to protein antigens in vivo. J Immunol (1995) 2.29
Monoclonal antibodies to murine CD3 epsilon define distinct epitopes, one of which may interact with CD4 during T cell activation. J Immunol (1989) 2.24
Late dominance of the inflammatory process in murine influenza by gamma/delta + T cells. J Exp Med (1990) 2.21
The relationship of IL-4- and IFN gamma-producing T cells studied by lineage ablation of IL-4-producing cells. Cell (1993) 2.19
Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers. J Exp Med (1977) 2.18
T-independent responses in B cell-defective CBA/N mice to Brucella abortus and to trinitrophenyl (TNP) conjugates of Brucella abortus. Eur J Immunol (1978) 2.13
Autocrine growth of CD4+ T cells. Differential effects of IL-1 on helper and inflammatory T cells. J Immunol (1988) 2.12
The rate of division of antibody-forming cells during the early primary immune response. J Exp Med (1968) 2.10
Cellular requirements for the primary in vitro antibody response to DNP-ficoll. J Exp Med (1974) 2.10
CD4+ T cells are required for development of a murine retrovirus-induced immunodeficiency syndrome (MAIDS). J Exp Med (1988) 2.06
CD4+ T cells: specificity and function. Immunol Rev (1988) 2.04
The ontogeny of thymic independent antibody responses in vitro in normal mice and mice with an X-linked B cell defect. J Immunol (1977) 2.03
XenCSA: cell surface antigens related to the major glycoproteins (gp70) of xenotropic murine leukemia viruses. J Immunol (1979) 2.02
Human immunodeficiency virus type 1 coreceptor switching: V1/V2 gain-of-fitness mutations compensate for V3 loss-of-fitness mutations. J Virol (2006) 2.00
Functional T lymphocytes are required for a murine retrovirus-induced immunodeficiency disease (MAIDS). J Exp Med (1987) 2.00
IL-4-independent induction of airway hyperresponsiveness by Th2, but not Th1, cells. J Immunol (1998) 1.92
Polarization of IL-4- and IFN-gamma-producing CD4+ T cells following activation of naive CD4+ T cells. J Immunol (1997) 1.90
Mice whose B cells cannot produce the T15 idiotype also lack an antigen-specific helper T cell required for T15 expression. J Exp Med (1979) 1.86
In vitro responses of CBA/N mice: spleen cells of mice with an X-linked defect that precludes immune responses to several thymus-independent antigens can respond to TNP-lipopolysaccharide. J Immunol (1976) 1.86
Cell surface appearance of unexpected host MHC determinants on thymocytes from radiation bone marrow chimeras. J Immunol (1981) 1.85
T helper 1 cells and interferon gamma regulate allergic airway inflammation and mucus production. J Exp Med (1999) 1.85
Role of dendritic cells in the priming of CD4+ T lymphocytes to peptide antigen in vivo. J Immunol (1993) 1.82
Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice. J Immunol (1990) 1.79
Th2 responses induced by epicutaneous or inhalational protein exposure are differentially dependent on IL-4. J Clin Invest (2000) 1.76
Functional maturation of thymic lymphocyte populations in vitro. J Exp Med (1972) 1.76
Cell surface antigen expression on thymocytes: development and phenotypic differentiation of intrathymic subsets. Immunol Rev (1984) 1.75
Selective activation of Th1- and Th2-like cells in vivo--response to human collagen IV. Immunol Rev (1991) 1.72
Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils. J Immunol (1999) 1.70
The effect of allogeneic presensitization on H-Y graft survival and in vitro cell-mediated responses to H-y antigen. J Exp Med (1976) 1.67
Expression of ets genes in mouse thymocyte subsets and T cells. J Immunol (1989) 1.65
Absence of an antigen-specific helper T cell required for the expression of the T 15 idiotype in mice treated with anti-mu antibody. Eur J Immunol (1980) 1.62
Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiation. J Immunol (1997) 1.61
Primary in vitro antibody responses by purified murine B lymphocytes in serum-free defined medium. J Immunol (1981) 1.61
The H-2 phenotype of the thymus dictates the self-specificity expressed by thymic but not splenic cytotoxic T lymphocyte precursors in thymus-engrafted nude mice. J Immunol (1981) 1.60
Differential activation of cytokine genes in normal CD4-bearing T cells is stimulus dependent. Eur J Immunol (1989) 1.57
Cellular deficit in thymectomized mice. Nature (1970) 1.57
Induction of IL-4-producing CD4+ T cells by antigenic peptides altered for TCR binding. J Immunol (1997) 1.56
Pneumococcal polysaccharides induce antibody formation by human B lymphocytes in vitro. J Immunol (1985) 1.55
Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands. Proc Natl Acad Sci U S A (1998) 1.50
In vitro studies of the genetically determined unresponsiveness to thymus-independent antigens in CBA/N mice. J Immunol (1976) 1.50
The role of surface IgD in the response to thymic-independent antigens. J Exp Med (1977) 1.46
MHC control of CD4+ T cell subset activation. J Exp Med (1989) 1.45
Heterogeneity of hematopoietic cells immortalized by v-myc/v-raf recombinant retrovirus infection of bone marrow or fetal liver. J Natl Cancer Inst (1989) 1.44
Lyb-7, a new B cell alloantigen controlled by genes linked to the IgCH locus. J Immunol (1979) 1.43
Characteristics of BALB/C T cell lymphomas grown as continuous in vitro lines. J Immunol (1978) 1.42
Survival of naive CD4 T cells: roles of restricting versus selecting MHC class II and cytokine milieu. J Immunol (1999) 1.42
Augmentation of organ-associated natural killer activity by biological response modifiers. Isolation and characterization of large granular lymphocytes from the liver. J Exp Med (1984) 1.41
Mediation of mouse natural cytotoxic activity by tumour necrosis factor. Nature (1986) 1.39
Ontogeny of mouse lymphocyte function. I. Paradoxical elevation of reactivity to allogeneic cells and phytohemagglutinin in BALB-c fetal thymocytes. J Immunol (1974) 1.39
STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation. Science (1999) 1.38
Activation of mouse lymphocytes by anti-immunoglobulin. II. A thymus-independent response by a mature subset of B lymphocytes. J Exp Med (1978) 1.37
CD4+ T-cell effectors inhibit Epstein-Barr virus-induced B-cell proliferation. J Virol (2001) 1.35
Animal models for retrovirus-induced immunodeficiency disease. Immunol Invest (1986) 1.34
The involvement of the intestinal microflora in the expansion of CD4+ T cells with a naive phenotype in the periphery. Dev Immunol (1992) 1.34
Ly phenotype and mechanism of action of mouse neonatal suppressor T cells. J Exp Med (1977) 1.33
Roles of IL-4 and IFN-gamma in stabilizing the T helper cell type 1 and 2 phenotype. J Immunol (1997) 1.33
Identification of human lung and skin proteins conjugated with hexamethylene diisocyanate in vitro and in vivo. Am J Respir Crit Care Med (2000) 1.32
Peptide and protein antigens require distinct antigen-presenting cell subsets for the priming of CD4+ T cells. J Immunol (1995) 1.32
Reciprocal regulation of CD30 expression on CD4+ T cells by IL-4 and IFN-gamma. J Immunol (1997) 1.29
hu-PBL-SCID mice: a model for human immune function, AIDS, and lymphomagenesis. Immunol Rev (1991) 1.29
Distinct patterns of membrane microdomain partitioning in Th1 and th2 cells. Immunity (2001) 1.28
Cytokines in T-cell development. Immunol Today (1991) 1.26
Differential T cell receptor-mediated signaling in naive and memory CD4 T cells. Eur J Immunol (1997) 1.23
Adoptive transfer of neonatal T lymphocytes rescues immunoglobulin production in mice with severe combined immune deficiency. J Exp Med (1991) 1.23
Steroid sensitivity of thymocyte subpopulations during intrathymic differentiation. Effects of 17 beta-estradiol and dexamethasone on subsets expressing T cell antigen receptor or IL-2 receptor. J Immunol (1989) 1.23
Activation status of the CD4-8- gamma delta-T cells recovered from mice with influenza pneumonia. J Immunol (1991) 1.21
Identification of the alternatively spliced exons of murine CD45 (T200) required for reactivity with B220 and other T200-restricted antibodies. J Exp Med (1989) 1.20
Role of a nonimmunoglobulin cell surface determinant in the activation of B lymphocytes by thymus-independent antigens. J Exp Med (1979) 1.19
Activation requirements for CD4+ T cells differing in CD45R expression. J Immunol (1992) 1.19