Clinical development of Orthoclone OKT3.

PubWeight™: 1.05‹?› | Rank: Top 15%

🔗 View Article (PMID 3105142)

Published in Transplant Proc on April 01, 1987

Authors

A B Cosimi

Articles by these authors

(truncated to the top 100)

Use of monoclonal antibodies to T-cell subsets for immunologic monitoring and treatment in recipients of renal allografts. N Engl J Med (1981) 3.63

Myeloma responses and tolerance following combined kidney and nonmyeloablative marrow transplantation: in vivo and in vitro analyses. Am J Transplant (2006) 3.34

Mixed allogeneic chimerism and renal allograft tolerance in cynomolgus monkeys. Transplantation (1995) 3.18

Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand. Nat Med (2000) 2.61

Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. Proc Natl Acad Sci U S A (1998) 2.29

Treatment of acute renal allograft rejection with OKT3 monoclonal antibody. Transplantation (1981) 2.22

Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: the induction of allograft tolerance through mixed lymphohematopoietic chimerism. Transplantation (1999) 2.16

Effective treatment of lymphedema of the extremities. Arch Surg (1998) 2.11

Native portal vein embolization for persistent hyperoxaluria following kidney and auxiliary partial liver transplantation. Am J Transplant (2013) 2.05

Changing pattern of organ donation at a single center: are potential brain dead donors being lost to donation after cardiac death? Am J Transplant (2010) 1.84

Controlled clinical trial of prophylactic human-leukocyte interferon in renal transplantation. Effects on cytomegalovirus and herpes simplex virus infections. N Engl J Med (1979) 1.83

Complement activation in acute humoral renal allograft rejection: diagnostic significance of C4d deposits in peritubular capillaries. J Am Soc Nephrol (1999) 1.77

Glomerulopathy associated with cytomegalovirus viremia in renal allografts. N Engl J Med (1981) 1.77

BK virus in solid organ transplant recipients: an emerging syndrome. Transplantation (2001) 1.75

Prognostic factors for melanoma patients with lesions 0.76 - 1.69 mm in thickness. An appraisal of "thin" level IV lesions. Ann Surg (1982) 1.72

Ultra-late recurrence (15 years or longer) of cutaneous melanoma. Cancer (1997) 1.71

Long-term outcome and alloantibody production in a non-myeloablative regimen for induction of renal allograft tolerance. Transplantation (1999) 1.66

Depletion of CD8 memory T cells for induction of tolerance of a previously transplanted kidney allograft. Am J Transplant (2007) 1.64

Plasma exchange and tacrolimus-mycophenolate rescue for acute humoral rejection in kidney transplantation. Transplantation (1998) 1.57

Tolerance in a concordant nonhuman primate model. Transplantation (1999) 1.53

Outcome of kidney transplantation using expanded criteria donors and donation after cardiac death kidneys: realities and costs. Am J Transplant (2007) 1.51

Long-term results in recipients of combined HLA-mismatched kidney and bone marrow transplantation without maintenance immunosuppression. Am J Transplant (2014) 1.49

Procurement of a whole pancreas and liver from the same cadaveric donor. Surgery (1989) 1.49

Preliminary results of a liver allocation plan using a continuous medical severity score that de-emphasizes waiting time. Liver Transpl (2001) 1.46

Modifications of the conditioning regimen for achieving mixed chimerism and donor-specific tolerance in cynomolgus monkeys. Transplantation (1997) 1.45

Use of CTLA4Ig for induction of mixed chimerism and renal allograft tolerance in nonhuman primates. Am J Transplant (2014) 1.44

Acute humoral rejection in renal allograft recipients: I. Incidence, serology and clinical characteristics. Transplantation (2001) 1.44

Infectious disease syndromes attributable to cytomegalovirus and their significance among renal transplant recipients. Transplantation (1977) 1.40

Phenotype, distribution and alloreactive properties of memory T cells from cynomolgus monkeys. Am J Transplant (2010) 1.39

Acute renal endothelial injury during marrow recovery in a cohort of combined kidney and bone marrow allografts. Am J Transplant (2011) 1.38

Posttransplant diabetes mellitus in liver transplant recipients: risk factors, temporal relationship with hepatitis C virus allograft hepatitis, and impact on mortality. Transplantation (2001) 1.38

Plasma interleukin 2 receptor levels in renal allograft recipients. Clin Immunol Immunopathol (1987) 1.38

A prognostic model for clinical stage I melanoma of the upper extremity. The importance of anatomic subsites in predicting recurrent disease. Ann Surg (1981) 1.38

Prognostic factors for patients with clinical stage I melanoma of intermediate thickness (1.51 - 3.39 mm). A conceptual model for tumor growth and metastasis. Ann Surg (1982) 1.38

A prognostic model for clinical stage I melanoma of the lower extremity. Location on foot as independent risk factor for recurrent disease. Surgery (1981) 1.33

Malignant melanoma patients with positive nodes and relatively good prognoses: microstaging retains prognostic significance in clinical stage I melanoma patients with metastases to regional nodes. Cancer (1981) 1.30

Hyperparathyroidism during pregnancy. Am J Surg (1976) 1.29

B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans. Am J Transplant (2009) 1.27

Immunosuppression and temporary skin transplantation in the treatment of massive third degree burns. Ann Surg (1975) 1.26

Infection in the renal transplant recipient. Am J Med (1981) 1.25

Monoclonal antibody therapy. Anti-idiotypic and non-anti-idiotypic antibodies to OKT3 arising despite intense immunosuppression. Transplantation (1986) 1.24

A multivariate analysis of prognostic factors for melanoma patients with lesions greater than or equal to 3.65 mm in thickness. The importance of revealing alternative Cox models. Ann Surg (1982) 1.24

Association of herpesvirus infections with T-lymphocyte-subset alterations, glomerulopathy, and opportunistic infections after renal transplantation. N Engl J Med (1983) 1.23

Evolving use of OKT3 monoclonal antibody for treatment of renal allograft rejection. Transplantation (1984) 1.20

Overcoming memory T-cell responses for induction of delayed tolerance in nonhuman primates. Am J Transplant (2011) 1.20

Effects of interferon-alpha on cytomegalovirus reactivation syndromes in renal-transplant recipients. N Engl J Med (1983) 1.18

Effects of antithymocyte globulin on cytomegalovirus infection in renal transplant recipients. Transplantation (1981) 1.18

Mechanisms of donor-specific tolerance in recipients of haploidentical combined bone marrow/kidney transplantation. Am J Transplant (2011) 1.17

Symptomatic cytomegalovirus disease in the cytomegalovirus antibody seropositive renal transplant recipient treated with OKT3. Transplantation (1992) 1.16

Characterization of a monoclonal antibody (6G12) recognizing the cynomolgus monkey CD3 antigen. Transplant Proc (1994) 1.15

Detection of microscopic melanoma metastases in sentinel lymph nodes. Cancer (1999) 1.15

Defective human mononuclear leukocyte chemotaxis as an index of host resistance to malignant melanoma. Clin Immunol Immunopathol (1976) 1.15

Liver transplantation for primary hepatic cancer. Transplantation (1992) 1.13

Evaluation in primate renal allograft recipients of monoclonal antibody to human T-cell subclasses. Transplant Proc (1981) 1.11

Four stages and lack of stable accommodation in chronic alloantibody-mediated renal allograft rejection in Cynomolgus monkeys. Am J Transplant (2008) 1.11

A phase I trial of immunosuppression with anti-ICAM-1 (CD54) mAb in renal allograft recipients. Transplantation (1993) 1.10

Disseminated intravascular coagulation in association with the delayed rejection of pig-to-baboon renal xenografts. Transplantation (1998) 1.09

Cynomolgus polyoma virus infection: a new member of the polyoma virus family causes interstitial nephritis, ureteritis, and enteritis in immunosuppressed cynomolgus monkeys. Am J Pathol (1999) 1.08

A randomized clinical trial comparing OKT3 and steroids for treatment of hepatic allograft rejection. Transplantation (1987) 1.07

Porcine kidney and heart transplantation in baboons undergoing a tolerance induction regimen and antibody adsorption. Transplantation (1999) 1.06

Antigenic polymorphism of the T4 differentiation antigen expressed on human T helper/inducer lymphocytes. Hum Immunol (1984) 1.06

De novo collapsing glomerulopathy in renal allografts. Transplantation (1998) 1.05

Viruses and thrombotic microangiopathy. Transplantation (1999) 1.05

The effect of infection on T lymphocyte subpopulations: a preliminary report. Int J Immunopharmacol (1981) 1.04

Idiopathic giant esophageal ulcers in a renal transplant patient responsive to steroid therapy. Transplantation (2000) 1.03

Effect of immunosuppressive therapy for renal allografts on the number of circulating sheep red blood cells rosetting cells. Transplantation (1975) 1.02

Hyperacute rejection of HLA-AB-identical renal allografts associated with B lymphocyte and endothelial reactive antibodies. Transplantation (1982) 1.01

Hepatic retransplantation in New England--a regional experience and survival model. Transplantation (1993) 1.01

Cardiovascular complications following liver transplantation. Clin Transplant (1995) 1.01

A prognostic model for clinical stage I melanoma of the trunk. Location near the midline is not an independent risk factor for recurrent disease. Am J Surg (1981) 1.01

The renal transplant patient with fever and pulmonary infiltrates: etiology, clinical manifestations, and management. Medicine (Baltimore) (1980) 1.01

Outcome of patients with melanoma and histologically negative sentinel lymph nodes. Arch Surg (1999) 1.00

Randomized clinical trial of antithymocyte globulin in cadaver renal allograft recipients: importance of T cell monitoring. Surgery (1976) 1.00

Hepatitis C virus-associated fibrosing cholestatic hepatitis after renal transplantation: response to interferon-alpha therapy. Transplantation (1998) 0.99

Use of antithymocyte globulin for reversal of acute allograft rejection. Transplantation (1979) 0.98

Transplantation. N Engl J Med (1979) 0.98

Cellular immune competence of breast cancer patients receiving radiotherapy. Arch Surg (1973) 0.98

Renal thrombotic microangiopathy associated with anticardiolipin antibodies in hepatitis C-positive renal allograft recipients. J Am Soc Nephrol (1999) 0.97

Predictors of late deaths among patients with clinical stage I melanoma who have not had bony or visceral metastases within the first 5 years after diagnosis. J Am Acad Dermatol (1983) 0.96

The faltering solid organ donor pool in the United States (2001-2010). World J Surg (2012) 0.95

IGA nephropathy in HLA-identical siblings. Transplantation (1978) 0.95

Successful treatment of invasive fungal infection with fluconazole in organ transplant recipients. Transplantation (1989) 0.94

Long-term metabolic and quality of life results with pancreatic/renal transplantation in insulin-dependent diabetes mellitus. Transplantation (1991) 0.94

A controlled study of trimethoprim-sulfamethoxazole prophylaxis of urinary tract infection in renal transplant recipients. Rev Infect Dis (1982) 0.94

Transplant center regulations--a mixed blessing? An ASTS Council viewpoint. Am J Transplant (2008) 0.93

Conservative surgical management of superficially invasive cutaneous melanoma. Cancer (1984) 0.93

Chronic antibody mediated rejection of renal allografts: pathological, serological and immunologic features in nonhuman primates. Am J Transplant (2006) 0.92

Prognosis after initial recurrence of cutaneous melanoma. Arch Surg (1991) 0.92

Cure of hemophilia A by orthotopic liver transplantation. Gastroenterology (1988) 0.92

Two-color flow cytometry and functional analysis of lymphocytes cultured from human renal allografts: identification of a Leu-2+3+ subpopulation. J Immunol (1986) 0.91

Accelerated acute rejection of an apparent A2 renal allograft in an O recipient: report of a case with flow cytometric analysis. Transplantation (1997) 0.91

Dosing of intravenous ganciclovir for the prophylaxis and treatment of cytomegalovirus infection in solid organ transplant recipients. Transplantation (2000) 0.91

Surgical management of primary cutaneous melanomas of the hands and feet. Ann Surg (1997) 0.90

Renal transplantation in the older age group. Arch Surg (1975) 0.89

Functional consequences of anti-ICAM-1 (CD54) in cynomolgus monkeys with renal allografts. Transplant Proc (1991) 0.89

The clinical usefulness of the renal allograft biopsy in the cyclosporine era: a prospective study. Transplantation (1999) 0.89

Mononuclear cells in acute allograft glomerulopathy. Am J Pathol (1987) 0.89

Porcine-to-primate orthotopic liver transplantation. Transplant Proc (1994) 0.89

Efficacy of tacrolimus as rescue therapy for chronic rejection in orthotopic liver transplantation: a report of the U.S. Multicenter Liver Study Group. Transplantation (1997) 0.88

Lymphedema after sentinel lymph node biopsy for cutaneous melanoma: a report of 5 cases. Arch Dermatol (2000) 0.88