Published in Stat Med on November 01, 1988
A Medical Research Council trial of two radiotherapy doses in the treatment of grades 3 and 4 astrocytoma. The Medical Research Council Brain Tumour Working Party. Br J Cancer (1991) 1.93
Data management for prospective research studies using SAS software. BMC Med Res Methodol (2008) 0.87
Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature (1997) 19.08
Design and serendipity in establishing a large cohort with wide dietary intake distributions : the National Institutes of Health-American Association of Retired Persons Diet and Health Study. Am J Epidemiol (2001) 11.17
A bacterial genome in flux: the twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burgdorferi. Mol Microbiol (2000) 7.60
Use of check lists in assessing the statistical content of medical studies. Br Med J (Clin Res Ed) (1986) 7.42
Breast cancer clusters in the northeast United States: a geographic analysis. Am J Epidemiol (1997) 5.73
Tables of the number of patients required in clinical trials using the logrank test. Stat Med (1983) 5.34
Allocation of patients to treatment groups in a controlled clinical study. Br J Cancer (1978) 5.25
Initiation of hypertension in utero and its amplification throughout life. BMJ (1993) 4.83
The prevalence of glaucoma in Chinese residents of Singapore: a cross-sectional population survey of the Tanjong Pagar district. Arch Ophthalmol (2000) 4.59
Scoring system to improve cost effectiveness of open access endoscopy. Br Med J (Clin Res Ed) (1983) 4.09
On the use of Pocock and Simon's method for balancing treatment numbers over prognostic factors in the controlled clinical trial. Biometrics (1976) 3.82
Adjuvant intra-arterial iodine-131-labelled lipiodol for resectable hepatocellular carcinoma: a prospective randomised trial. Lancet (1999) 3.54
Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res (1978) 3.51
Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer: results from five randomized controlled trials. International Collaborative Hyperthermia Group. Int J Radiat Oncol Biol Phys (1996) 3.42
Deprivation and general practitioner workload. BMJ (1992) 3.13
Socioeconomic differentials in the uptake of medical care in Great Britain. J Epidemiol Community Health (1987) 2.99
Alpha-Tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance. J Natl Cancer Inst (1996) 2.98
Fetal, infant, and childhood growth and adult blood pressure: a longitudinal study from birth to 22 years of age. Circulation (2002) 2.84
Intention to treat--who should use ITT? Br J Cancer (1993) 2.74
A randomized controlled trial of adjuvant portal vein cytotoxic perfusion in colorectal cancer. Br J Surg (1985) 2.66
Use of synthetic peptides derived from the antigens ESAT-6 and CFP-10 for differential diagnosis of bovine tuberculosis in cattle. Clin Diagn Lab Immunol (2001) 2.57
The treatment of Wilms' tumor: results of the Second National Wilms' Tumor Study. Cancer (1981) 2.43
Implications of a new dietary measurement error model for estimation of relative risk: application to four calibration studies. Am J Epidemiol (1999) 2.40
A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients. EORTC Quality of Life Group. Eur J Cancer (2000) 2.34
Randomised trial of two regimens of chemotherapy in operable osteosarcoma: a study of the European Osteosarcoma Intergroup. Lancet (1997) 2.33
Empirical evidence of correlated biases in dietary assessment instruments and its implications. Am J Epidemiol (2001) 2.33
Quality of life in head and neck cancer patients: validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-H&N35. J Clin Oncol (1999) 2.25
Health risks associated with bathing in sea water. BMJ (1991) 2.24
Injuries sustained on "bouncy castles". BMJ (1992) 2.20
Fever treatment and household wealth: the challenge posed for rolling out combination therapy for malaria. Trop Med Int Health (2006) 2.18
The Small Area Health Statistics Unit: a national facility for investigating health around point sources of environmental pollution in the United Kingdom. J Epidemiol Community Health (1992) 2.15
Detection of gonioscopically occludable angles and primary angle closure glaucoma by estimation of limbal chamber depth in Asians: modified grading scheme. Br J Ophthalmol (2000) 2.11
Randomised consent designs in cancer clinical trials. Eur J Cancer (1995) 2.07
Competing risks analysis of patients with osteosarcoma: a comparison of four different approaches. Stat Med (2001) 2.04
Doctors on tribunals. A confusion of roles. Br J Psychiatry (2000) 2.02
On the evaluation of the clinical effects of acupuncture. Pain (1983) 2.01
Prospective testing of a scoring system designed to improve case selection for upper gastrointestinal investigation. Gastroenterology (1986) 1.98
Development of diagnostic reagents to differentiate between Mycobacterium bovis BCG vaccination and M. bovis infection in cattle. Clin Diagn Lab Immunol (1999) 1.97
Randomized trial of palliative two-fraction versus more intensive 13-fraction radiotherapy for patients with inoperable non-small cell lung cancer and good performance status. Medical Research Council Lung Cancer Working Party. Clin Oncol (R Coll Radiol) (1996) 1.93
Histological grade and other prognostic factors in relation to survival of patients with breast cancer. Br J Cancer (1979) 1.92
Is the statistical assessment of papers submitted to the "British Medical Journal" effective? Br Med J (Clin Res Ed) (1983) 1.92
The CHART trials: Bayesian design and monitoring in practice. CHART Steering Committee. Stat Med (1994) 1.90
Effect of measles vaccination on incidence of measles in the community. Br Med J (1971) 1.85
Cadmium fume inhalation and emphysema. Lancet (1988) 1.84
Potential impact of genetic testing on cancer prevention trials, using breast cancer as an example. J Natl Cancer Inst (1995) 1.84
The costs of changing national policy: lessons from malaria treatment policy guidelines in Tanzania. Trop Med Int Health (2006) 1.83
A predictive approach to selecting the size of a clinical trial, based on subjective clinical opinion. Stat Med (1986) 1.82
The autopsy: a useful tool or an old relic? J Pathol (1988) 1.81
Histopathology in the prediction of relapse of patients with stage I testicular teratoma treated by orchidectomy alone. Lancet (1987) 1.79
Anterior chamber depth measurement as a screening tool for primary angle-closure glaucoma in an East Asian population. Arch Ophthalmol (2000) 1.76
Statistical distributions of diagnostic phrases of morbidity and mortality. Int J Biomed Comput (1972) 1.76
Incomplete quality of life data in randomized trials: missing items. Stat Med (1998) 1.71
Bovine tuberculosis in domestic cats. Vet Rec (2000) 1.65
The effect of intravesical mitomycin C on recurrence of newly diagnosed superficial bladder cancer: a further report with 7 years of follow up. J Urol (1996) 1.63
Accuracy of clinical estimates of intraocular pressure in Chinese eyes. Ophthalmology (2000) 1.63
Interpreting precursor studies: what polyp trials tell us about large-bowel cancer. J Natl Cancer Inst (1994) 1.61
Using reference data on quality of life--the importance of adjusting for age and gender, exemplified by the EORTC QLQ-C30 (+3). Eur J Cancer (1998) 1.60
Measuring and analysing quality of life in cancer clinical trials: a review. Stat Med (1984) 1.60
Health-related quality of life in the general Norwegian population assessed by the European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionnaire: the QLQ=C30 (+ 3). J Clin Oncol (1998) 1.59
Guidelines for reporting results of quality of life assessments in clinical trials. Qual Life Res (1996) 1.58
Myelodysplastic syndromes: a scoring system with prognostic significance. Br J Haematol (1985) 1.57
Can energy adjustment separate the effects of energy from those of specific macronutrients? Am J Epidemiol (1994) 1.56
Seasonality of suicide in Singapore: data from the equator. Psychol Med (2001) 1.54
Relationship among outcome, stage of disease, and histologic grade for 22,616 cases of breast cancer. The basis for a prognostic index. Cancer (1991) 1.49
Response to N7 induction chemotherapy in children more than one year of age diagnosed with metastatic neuroblastoma treated in UKCCSG centers. Pediatr Blood Cancer (2007) 1.49
The use of a Kolmogorov--Smirnov type statistic in testing hypotheses about seasonal variation. J Epidemiol Community Health (1979) 1.49
A community-based study of scaling assumptions and construct validity of the English (UK) and Chinese (HK) SF-36 in Singapore. Qual Life Res (2001) 1.48
Trends in induced abortion in England and Wales. J Epidemiol Community Health (1983) 1.46
Life after radiotherapy: the psychological and social effects experienced by women treated for advanced stages of cervical cancer. Gynecol Oncol (2000) 1.45
Surgery and adjuvant radiotherapy vs concurrent chemoradiotherapy in stage III/IV nonmetastatic squamous cell head and neck cancer: a randomised comparison. Br J Cancer (2005) 1.42
Coping with extra Poisson variability in the analysis of factors influencing vaginal ring expulsions. Stat Med (1991) 1.42
Emergency department patients who leave without seeing a physician: the Toronto Hospital experience. Ann Emerg Med (1994) 1.41
Bayesian monitoring of phase II trials in cancer chemoprevention. J Clin Epidemiol (1999) 1.41
A stratified Wilcoxon-type test for trend. Stat Med (1990) 1.40
The future of prognostic factors in outcome prediction for patients with cancer. Cancer (1992) 1.39
Effect of intravesical mitomycin C on recurrence of newly diagnosed superficial bladder cancer: interim report from the Medical Research Council Subgroup on Superficial Bladder Cancer (Urological Cancer Working Party). Br Med J (Clin Res Ed) (1988) 1.39
Thirty years of Medical Research Council randomized trials in solid tumours. Clin Oncol (R Coll Radiol) (1997) 1.38
Randomised trial of compliance with screening for colorectal cancer. Br Med J (Clin Res Ed) (1986) 1.38
Blood pressure in four and five-year-old children: the effects of environment and other factors in it's measurement--the Brompton study. J Hypertens (1984) 1.38
Interpreting quality of life data: population-based reference data for the EORTC QLQ-C30. Eur J Cancer (2001) 1.35
Incomplete quality of life data in randomized trials: missing forms. Stat Med (1998) 1.34
Socioeconomic status, systolic blood pressure and intraocular pressure: the Tanjong Pagar Study. Br J Ophthalmol (2006) 1.34
Randomized trials with quality of life endpoints: are doctors' ratings of patients' physical symptoms interchangeable with patients' self-ratings? Qual Life Res (1997) 1.33
Stopping rules for clinical trials incorporating clinical opinion. Biometrics (1984) 1.33
Quality of life assessment in clinical trials--guidelines and a checklist for protocol writers: the U.K. Medical Research Council experience. MRC Cancer Trials Office. Eur J Cancer (1997) 1.32
Effect of starvation on the tissue composition of the small intestine in the rat. Am J Physiol (1968) 1.31
Variations in the level of reporting by hospitals to a regional cancer registry. Br J Cancer (1978) 1.29
Randomised comparative studies in the treatment of cancer in the United Kingdom: room for improvement? Lancet (1979) 1.29
Acupuncture compared with placebo in post-herpetic pain. Pain (1983) 1.29
Young age is not a poor prognostic marker in colorectal cancer. Br J Surg (1998) 1.28
Influence from genetic variability on opioid use for cancer pain: a European genetic association study of 2294 cancer pain patients. Pain (2011) 1.28
Randomized, placebo-controlled, double-blind study of low-dose oral interferon-alpha in HIV-1 antibody positive patients. J Acquir Immune Defic Syndr (1992) 1.27
An assay for dopamine-beta-hydroxylase activity in tissues and serum. Experientia (1971) 1.26
Approaches to the analysis of quality of life data: experiences gained from a medical research council lung cancer working party palliative chemotherapy trial. Qual Life Res (1994) 1.26
A survey of deaths in Hong Kong attributed to tuberculosis. Tubercle (1981) 1.24