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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.

PubWeight™: 10.16‹?› | Rank: Top 0.1%

🔗 View Article (PMID 32171076)

Published in Lancet on March 11, 2020

Authors

Fei Zhou1, Ting Yu2, Ronghui Du3, Guohui Fan4, Ying Liu2, Zhibo Liu1, Jie Xiang5, Yeming Wang6, Bin Song2, Xiaoying Gu4, Lulu Guan3, Yuan Wei2, Hui Li1, Xudong Wu7, Jiuyang Xu8, Shengjin Tu2, Yi Zhang1, Hua Chen9, Bin Cao10

Author Affiliations

1: Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
2: Department of Tuberculosis and Respiratory Disease, Jinyintan Hospital, Wuhan, China.
3: Department of Pulmonary and Critical Care Medicine, Wuhan Pulmonary Hospital, Wuhan, China.
4: Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China; Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing, China.
5: Department of Clinical Laboratory, Jinyintan Hospital, Wuhan, China.
6: Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China; Department of Respiratory Medicine, Capital Medical University, Beijing, China.
7: GCP Center, Jinyintan Hospital, Wuhan, China.
8: Tsinghua University School of Medicine, Beijing, China.
9: Department of Tuberculosis and Respiratory Disease, Jinyintan Hospital, Wuhan, China. Electronic address: 2716637947@qq.com.
10: Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China; Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China; Department of Respiratory Medicine, Capital Medical University, Beijing, China; Tsinghua University School of Medicine, Beijing, China. Electronic address: caobin_ben@163.com.

Associated clinical trials:

Baricitinib in Symptomatic Patients Infected by COVID-19: an Open-label, Pilot Study. (BARI-COVID) | NCT04320277

Prognostic Factors Keeping Track for COVID-19 Pneumonia (NIKE_C19) | NCT04324684

Safety and Efficacy of Hyperbaric Oxygen for ARDS in Patients With COVID-19 (COVID-19-HBO) | NCT04327505

Tocilizumab in the Treatment of Coronavirus Induced Disease (COVID-19) (CORON-ACT) | NCT04335071

Impact of Covid-19 in Congenital Heart Disease (COVID-CHD) | NCT04336384

Hemodynamic Characteristics of Patients With SARS-CoV-2 (PiCCOVID) | NCT04337983

Elimination or Prolongation of ACE Inhibitors and ARB in Coronavirus Disease 2019 (REPLACECOVID) | NCT04338009

Azithromycin Added to Hydrochloroquine in Patients Admitted to Intensive Care With COVID-19: Randomised Controlled Trial (AZIQUINE-ICU) | NCT04339816

Hydroxychloroquine With or Without Azithromycin for Virologic Cure of COVID-19 | NCT04349592

Prophylactic Corticosteroid to Prevent COVID-19 Cytokine Storm | NCT04355247

Computed Tomography for COVID-19 Diagnosis (STOIC) | NCT04355507

Cardiac Arrhythmias In Patients With Coronavirus Disease (COVID-19) | NCT04358029

Ruxolitinib for Treatment of Covid-19 Induced Lung Injury ARDS (RuXoCoil) | NCT04359290

COVID-19 Patient Positioning Pragmatic Trial | NCT04359797

Impact of Prone Position in Patients Under Spontaneous Breathing on Intubation or Non-invasive Ventilation or Death Incidence During COVID-19 Acute Respiratory Distress (PROVID-19) | NCT04363463

Multicenter, Retrospective Study of the Effects of Remdesivir in the Treatment of Severe Covid-19 Infections (REMDECO-19) | NCT04365725

African Covid-19 Critical Care Outcomes Study | NCT04367207

C5a Receptor Expression - COVID-19 (C5-COV) (C5-COV) | NCT04369820

Efficacy of Convalescent Plasma Therapy in the Early Care of COVID-19 Patients. (PLASCOSSA) | NCT04372979

Understanding Community Considerations, Opinions, Values, Impacts, and Decisions for COVID-19 (UC-COVID) | NCT04373135

COVID19-FOIE National Observatory | NCT04375670

Quality of Life and Physical Performance After Novel Coronavirus Infection (COVID-19); | NCT04375709

InterLeukin-7 (CYT107) to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection UK Cohort (ILIAD-7-UK) | NCT04379076

Analysis of Mortality of Critically Ill Patients With COVID-19 | NCT04379258

Risk Factors Worsening COVID19 for Out-patient With Home Monitoring (COVIDADOMEVA) | NCT04380662

Almitrine and COVID-19 Related Hypoxemia | NCT04380727

Direct and Indirect Impact of COVID-19 In Older Populations (COVID-OLD) | NCT04381312

The Global PCHF-COVICAV Registry (PCHF-COVICAV) | NCT04390555

Lung CT Scan Analysis of SARS-CoV2 Induced Lung Injury (TAC-COVID19) | NCT04395482

COVID-19 Associated Lymphopenia Pathogenesis Study in Blood (CALYPSO) | NCT04401436

Study on Safety and Efficacy of Favipiravir (Favipira) for COVID-19 Patient in Selected Hospitals of Bangladesh | NCT04402203

The Utility of Enhanced Pre and Post-surgical Work-out to Prevent the Spread of COVID-19 in a Large Urology Department (UroCovid) | NCT04409899

Pulmonary Optical Coherence Tomography in COVID-19 Patients | NCT04410549

Effect of Using Barrier Devices for Intubation in COVID-19 Patients | NCT04412226

Prevalence and Characteristics of Pulmonary Embolism on COVID-19 Patients Presenting Respiratory Symptoms (COVID-EP) | NCT04420312

Use of Remote Monitoring for COVID-19 Patient (RPM) | NCT04425720

Low Dose Whole Lung Radiation Therapy for Patients With COVID-19 and Respiratory Compromise (VENTED) | NCT04427566

BNP, Serum Troponin and D-dimer as Risk Factors in Patients With COVID-19 | NCT04433026

Evaluation of Immune Response in COVID-19 Patients (IMMUNOVID) | NCT04438629

Effect of COVID-19 on Platelet Aggregation | NCT04447131

Nutritional Habits, and Coronavirus Disease 2019 (COVID-19) Outcome | NCT04447144

Arrhythmic Manifestations and Management in Hospitalized COVID-19 Patients | NCT04465552

Efficacy of Pre-exposure Treatment With Hydroxy-Chloroquine on the Risk and Severity of COVID-19 Infection (PREPCOV) | NCT04481633

Decitabine for Coronavirus (COVID-19) Pneumonia- Acute Respiratory Distress Syndrome (ARDS) Treatment: DART Trial (DART) | NCT04482621

Sildenafil in COVID-19 | NCT04489446

Anti-thrombotics for Adults Hospitalized With COVID-19 | NCT04505774

The McGill RAAS-COVID-19 Randomized Controlled Trial (RAAS-COVID) | NCT04508985

Convalescent Plasma in the Early Treatment of High-Risk Patients With SARS-CoV-2 (COVID-19) Infection | NCT04513158

Allocetra-OTS in COVID-19 | NCT04513470

Fenofibrate Intervention as COVID-19 Therapy (FERMIN) | NCT04517396

Coronavirus Induced Acute Kidney Injury: Prevention Using Urine Alkalinization | NCT04530448

Nebulized Heparin in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (NEBUHEPA) | NCT04530578

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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet (2020) 18.32

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