Use of OKT3 with cyclosporin and steroids for reversal of acute kidney and liver allograft rejection.

PubWeight™: 3.26‹?› | Rank: Top 1%

🔗 View Article (PMC 2994552)

Published in Nephron on January 01, 1987


J J Fung, A J Demetris, K A Porter, S Iwatsuki, R D Gordon, C O Esquivel, R Jaffe, A Tzakis, B W Shaw, T E Starzl

Articles citing this

Kidney transplantation under FK 506. JAMA (1990) 7.45

Extended preservation of human liver grafts with UW solution. JAMA (1989) 3.99

Biliary tract complications in human orthotopic liver transplantation. Transplantation (1987) 2.95

Functional characterization of infiltrating T lymphocytes in human hepatic allografts. Hum Immunol (1986) 2.84

The antibody crossmatch in liver transplantation. Surgery (1986) 2.33

The point system for organ distribution. Transplant Proc (1989) 1.88

Orthotopic liver transplantation for alcoholic cirrhosis. JAMA (1988) 1.45

Combined liver-kidney transplantation: analysis of patients with preformed lymphocytotoxic antibodies. Transplant Proc (1988) 1.38

Transplantation in HIV+ patients. Transplantation (1990) 1.29

Successful sequential liver-kidney transplantation in a patient with performed lymphocytotoxic antibodies. Transplant Proc (1987) 1.25

Liver transplantation in the treatment of primary liver cancer. Hepatogastroenterology (1990) 1.24

Origin of lymph node-derived lymphocytes in human hepatic allografts. Clin Transpl (1989) 1.24

Renal transplantation in black recipients at the University of Pittsburgh. Transplant Proc (1989) 1.19

OKT3 and viral disease in pediatric liver transplant recipients. Clin Transplant (1991) 1.11

Pediatric liver transplantation. Transplant Proc (1987) 1.03

Cadaveric renal transplantation under the American organ allocation system. Contrib Nephrol (1989) 0.93

Low rate of Rhesus immunization from Rh-incompatible blood transfusions during liver and heart transplant surgery. Transplantation (1989) 0.90

Cadaveric renal transplantation at the University of Pittsburgh: a two and one-half-year experience with the point system. Clin Transpl (1988) 0.90

Red cell antibody problems in 1000 liver transplants. Transfusion (1989) 0.87

Surgical complications in human orthotopic liver transplantation. Acta Chir Belg (1987) 0.85

Monoclonal antibody therapy with ciclosporin and steroids in nonmatched cadaveric renal transplants. Nephron (1987) 0.85

Progress in liver transplantation. Adv Surg (1988) 0.83

Current status of renal transplantation. West J Med (1990) 0.81

Experience with Orthoclone OKT3 monoclonal antibody in liver transplantation. Am J Kidney Dis (1988) 0.80

The Denver-Pittsburgh liver transplant series. Clin Transpl (1987) 0.79

Donor gender does not affect liver transplantation outcome in children. Dig Dis Sci (1990) 0.79

The University of Pittsburgh: a three and three-quarter-year experience with cadaveric renal transplantation under the point system. Clin Transpl (1989) 0.77

The Lewis blood group system in liver transplantation. Transplant Proc (1987) 0.75

Transplantation. JAMA (1986) 0.75

Prophylactic use of OKT3 in liver transplantation. A review. Dig Dis Sci (1991) 0.75

WHICH LIVER-DESEASE PATIENTS NEED A TRANSPLANT?: Organ replacement has come into its own as a treatment for end-stage liver disease. A team of experts from two leading transplant centers reviews current indications, survival rates, and methods of evaluating candidates for operation. Hosp Rec Study (1988) 0.75

Articles cited by this

Continuous cultures of fused cells secreting antibody of predefined specificity. Nature (1975) 83.56

Monoclonal antibodies defining distinctive human T cell surface antigens. Science (1979) 10.50


The use of cyclosporin A and prednisone in cadaver kidney transplantation. Surg Gynecol Obstet (1980) 7.40

The use of heterologous antilymphoid agents in canine renal and liver homotransplantation and in human renal homotransplantation. Surg Gynecol Obstet (1967) 7.24

Fifteen years of clinical liver transplantation. Gastroenterology (1979) 7.19

Orthotopic homotransplantation of the human liver. Ann Surg (1968) 6.64

Cyclosporin A in patients receiving renal allografts from cadaver donors. Lancet (1979) 6.10

The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level. J Immunol (1984) 5.80

OKT3: a monoclonal anti-human T lymphocyte antibody with potent mitogenic properties. J Immunol (1980) 5.63

Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line. J Exp Med (1984) 5.26

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex. Cell (1982) 4.86

Use of monoclonal antibodies to T-cell subsets for immunologic monitoring and treatment in recipients of renal allografts. N Engl J Med (1981) 3.63

Does OKT3 monoclonal antibody react with an antigen-recognition structure on human T cells? Proc Natl Acad Sci U S A (1981) 3.09

Successful liver transplantation from crossmatch-positive donors. Transplant Proc (1981) 2.80

Mechanism of T cell activation: role and functional relationship of HLA-DR antigens and interleukins. Immunol Rev (1982) 2.44

Variable convalescence and therapy after cadaveric renal transplantation under cyclosporin A and steroids. Surg Gynecol Obstet (1982) 2.42

Treatment of acute renal allograft rejection with OKT3 monoclonal antibody. Transplantation (1981) 2.22

Tolerance of T-cell clones is associated with membrane antigen changes. Nature (1983) 2.10


Pharmacokinetics and monitoring of cyclosporine following orthotopic liver transplantation. Semin Liver Dis (1985) 1.61

A randomized clinical trial of OKT3 monoclonal antibody for acute rejection of cadaveric renal transplants. Ortho Multicenter Transplant Study Group. N Engl J Med (1985) 1.57

Survival of skin heterografts under treatment with antilymphocytic serum. Lancet (1968) 1.39

Seven years' experience with antilymphoblast globulin for renal transplantation from cadaver donors. Ann Surg (1976) 1.26

Evolving use of OKT3 monoclonal antibody for treatment of renal allograft rejection. Transplantation (1984) 1.20

OKT8 antibody inhibits OKT3-induced IL 2 production and proliferation in OKT8+ cells. J Immunol (1983) 1.19

Effects of antithymocyte globulin on cytomegalovirus infection in renal transplant recipients. Transplantation (1981) 1.18

Renal failure in children with hepatic failure undergoing liver transplantation. J Pediatr (1986) 1.14

Evaluation in primate renal allograft recipients of monoclonal antibody to human T-cell subclasses. Transplant Proc (1981) 1.11

Human T lymphocyte activation by monoclonal antibodies; OKT3, but not UCHT1, triggers mitogenesis via an interleukin 2-dependent mechanism. J Immunol (1984) 1.06

Treatment of acute graft-versus-host disease with monoclonal antibody OKT3. Clinical results and effect on circulating T lymphocytes. Transplantation (1984) 0.98

Use of antithymocyte globulin for reversal of acute allograft rejection. Transplantation (1979) 0.98

Use of antithymocyte globulin in human heart transplantation. Circulation (1972) 0.85

OKT3 monoclonal antibody inhibits cytotoxic T lymphocyte mediated cell lysis. Int J Immunopharmacol (1981) 0.83

Modification of established rejection of canine kidney and liver homografts with antilymphocyte gamma-G globulin. Surgery (1969) 0.82

A reappraisal of the effects of monoclonal antibodies directed at T cell differentiation antigens. Transplantation (1984) 0.82

Radionuclides in renal transplantation. J Nucl Med (1972) 0.82

Antithymocyte globulin as the primary treatment for renal allograft rejection. Transplantation (1983) 0.82

Articles by these authors

Evolution of liver transplantation. Hepatology (1982) 19.54

FK 506 for liver, kidney, and pancreas transplantation. Lancet (1989) 13.70

Cell migration, chimerism, and graft acceptance. Lancet (1992) 12.24

A flexible procedure for multiple cadaveric organ procurement. Surg Gynecol Obstet (1984) 10.33

The Banff 97 working classification of renal allograft pathology. Kidney Int (1999) 9.02

Cell migration and chimerism after whole-organ transplantation: the basis of graft acceptance. Hepatology (1993) 8.76

Orthotopic liver transplantation in ninety-three patients. Surg Gynecol Obstet (1976) 8.11

Kidney transplantation under FK 506. JAMA (1990) 7.45

The use of cyclosporin A and prednisone in cadaver kidney transplantation. Surg Gynecol Obstet (1980) 7.40

The use of heterologous antilymphoid agents in canine renal and liver homotransplantation and in human renal homotransplantation. Surg Gynecol Obstet (1967) 7.24

Fifteen years of clinical liver transplantation. Gastroenterology (1979) 7.19

Venous bypass in clinical liver transplantation. Ann Surg (1984) 7.04

Liver transplantation with use of cyclosporin a and prednisone. N Engl J Med (1981) 6.95

The many faces of multivisceral transplantation. Surg Gynecol Obstet (1991) 6.89

Orthotopic homotransplantation of the human liver. Ann Surg (1968) 6.64

Vascular homografts from cadaveric organ donors. Surg Gynecol Obstet (1979) 6.23

Long survival in rats after multivisceral versus isolated small-bowel allotransplantation under FK 506. Surgery (1991) 5.92

Abdominal organ cluster transplantation for the treatment of upper abdominal malignancies. Ann Surg (1989) 5.78

Infections after liver transplantation. An analysis of 101 consecutive cases. Medicine (Baltimore) (1988) 5.77

Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy. Lancet (1984) 5.74

Refinements in the surgical technique of liver transplantation. Semin Liver Dis (1985) 5.70

Bone marrow augmentation of donor-cell chimerism in kidney, liver, heart, and pancreas islet transplantation. Lancet (1994) 5.54

In vitro cell-mediated immune responses to the male specific(H-Y) antigen in mice. J Exp Med (1975) 5.53

Progress in and deterrents to orthotopic liver transplantation, with special reference to survival, resistance to hyperacute rejection, and biliary duct reconstruction. Transplant Proc (1974) 5.53

Extended survival in 3 cases of orthotopic homotransplantation of the human liver. Surgery (1968) 5.44

Banff '05 Meeting Report: differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN'). Am J Transplant (2007) 5.39

Cyclophosphamide and whole organ transplantation in human beings. Surg Gynecol Obstet (1971) 5.24

Alternative methods of arterialization of the hepatic graft. Surg Gynecol Obstet (1984) 5.16

Immunosuppression of canine, monkey, and baboon allografts by FK 506: with special reference to synergism with other drugs and to tolerance induction. Surgery (1988) 5.03

Liver, kidney, and thoracic organ transplantation under FK 506. Ann Surg (1990) 5.01

Intestinal transplantation in composite visceral grafts or alone. Ann Surg (1992) 4.96

Conversion from cyclosporine to FK 506 in liver allograft recipients with cyclosporine-related complications. Transplant Proc (1990) 4.90

Liver transplantation (1). N Engl J Med (1989) 4.53

Pancreaticoduodenal transplantation in humans. Surg Gynecol Obstet (1984) 4.49

Murine liver allograft transplantation: tolerance and donor cell chimerism. Hepatology (1994) 4.32

A simplified technique for revascularization of homografts of the liver with a variant right hepatic artery from the superior mesenteric artery. Surg Gynecol Obstet (1985) 4.29

Donor cell chimerism permitted by immunosuppressive drugs: a new view of organ transplantation. Immunol Today (1993) 4.29

Heterotopic heart transplantation in the rat receiving FK-506 alone or with cyclosporine. Transplant Proc (1987) 4.21

Pancreatic islet transplantation after upper abdominal exenteration and liver replacement. Lancet (1990) 4.18

Experience in hepatic resection for metastatic colorectal cancer: analysis of clinical and pathologic risk factors. Surgery (1994) 4.16

Orthotopic liver transplantation with preservation of the inferior vena cava. Ann Surg (1989) 4.12

Malignant lymphomas in transplantation patients. Transplant Proc (1969) 4.12

Role of liver transplantation in cancer therapy. Ann Surg (1985) 4.08

Biliary complications after liver transplantation: with special reference to the biliary cast syndrome and techniques of secondary duct repair. Surgery (1977) 4.08

Shwartzman reaction after human renal homotransplantation. N Engl J Med (1968) 4.05

Baboon-to-human liver transplantation. Lancet (1993) 4.01

Extended preservation of human liver grafts with UW solution. JAMA (1989) 3.99

Canine and human liver preservation for 6 to 18 hr by cold infusion. Transplantation (1977) 3.99

Liver transplantation in the United States, 1999-2008. Am J Transplant (2010) 3.92