Published in Nature on February 22, 1979
Activation of phospholipases A and C in human platelets exposed to epinephrine: role of glycoproteins IIb/IIIa and dual role of epinephrine. Proc Natl Acad Sci U S A (1986) 1.84
Platelet alpha-adrenoceptors--a valid model for brain or vascular adrenoceptors? Br J Clin Pharmacol (1986) 1.12
The effects of fenfluramine on in vitro platelet aggregation. Br J Clin Pharmacol (1982) 1.12
Interaction of selective alpha-adrenoceptor agonists and antagonists with human and rabbit blood platelets. Br J Pharmacol (1980) 1.10
Solubilization of human platelet alpha-adrenergic receptors: evidence that agonist occupancy of the receptor stabilizes receptor--effector interactions. Proc Natl Acad Sci U S A (1981) 1.07
Increased numbers of alpha receptors in sympathetic denervation supersensitivity in man. J Clin Invest (1982) 1.05
The Fourth Lilly Prize Lecture, University of Aberdeen, September 1980. The clinical pharmacology of clonidine and related central antihypertensive agents. Br J Clin Pharmacol (1981) 0.98
1-O-hexadecyl-2-acetyl-sn-glycero-3-phospho (N,N,N trimethyl) hexanolamine: an analogue of platelet-activating factor with partial agonist activity. Br J Pharmacol (1991) 0.94
The binding characteristics of [3H]-dihydroergocryptine on intact human platelets. Br J Pharmacol (1982) 0.92
Platelet beta-adrenoceptors. Br J Pharmacol (1983) 0.90
Synergism between thrombin and adrenaline (epinephrine) in human platelets. Marked potentiation of inositol phospholipid metabolism. Biochem J (1988) 0.90
Mammalian platelet adrenoceptors. Br J Pharmacol (1984) 0.89
Acute reduction in human platelet alpha 2-adrenoreceptor affinity for agonist by endogenous and exogenous catecholamines. J Clin Invest (1983) 0.87
Prolonged platelet activation in individuals with elevated blood pressure in response to a moderate exercise challenge. Psychophysiology (2009) 0.85
A preliminary, clinical pharmacological assessment of L-659,066, a novel alpha 2-adrenoceptor antagonist. Br J Clin Pharmacol (1992) 0.84
Effects of alpha 2-adrenoceptor agonists and of related compounds on aggregation of, and on adenylate cyclase activity in, human platelets. Br J Pharmacol (1984) 0.83
Variations in circulating catecholamines fail to alter human platelet alpha-2-adrenergic receptor number or affinity for [3H]yohimbine or [3H]dihydroergocryptine. J Clin Invest (1984) 0.80
Interaction between the effects of 5-hydroxytryptamine and adrenaline on the growth of platelet thrombi in the coronary artery of the anaesthetized dog. Br J Pharmacol (1993) 0.80
Affinity chromatography of human platelet alpha 2-adrenergic receptors. Proc Natl Acad Sci U S A (1982) 0.79
Treadmill exercise promotes cyclic alterations in coronary blood flow in dogs with coronary artery stenoses and endothelial injury. J Clin Invest (1989) 0.79
Potentiation of ADP-induced aggregation in human platelet-rich plasma by 5-hydroxytryptamine and adrenaline. Br J Pharmacol (1992) 0.79
Redirection of arachidonic acid metabolism by ICI D1542: effects on thrombus formation in the coronary artery of the anaesthetized dog. Br J Pharmacol (1993) 0.79
Epinephrine at doses used in dentistry deteriorates platelet retention rate. Anesth Prog (1997) 0.78
Regulation of platelet function by catecholamines in the cerebral vasculature of the rabbit. Br J Pharmacol (1999) 0.78
Evidence for a non-adrenoceptor, imidazoline-mediated contractile response to oxymetazoline in the porcine isolated rectal artery. Br J Pharmacol (2001) 0.77
Effect of 781094, a new selective alpha-adrenoceptor antagonist, on the aggregatory responses of human blood platelets and on binding of [3H]-dihydroergocryptine to these cells. Br J Pharmacol (1983) 0.75
The potentiation of adrenaline-induced in vitro platelet aggregation by ADP, collagen and serotonin and its inhibition by naftopidil and doxazosin in normal human subjects. Br J Clin Pharmacol (1995) 0.75
The effect of fenfluramine on collagen-induced platelet aggregation in vitro. Br J Clin Pharmacol (1983) 0.75
Lisinopril and nifedipine administration inhibits the ex vivo uptake of [45Ca2+] by platelets from hypertensive diabetic patients. Br J Clin Pharmacol (1992) 0.75
The association between the melanocyte-stimulating hormone receptor and the alpha 2-adrenoceptor on the Anolis melanophore. Br J Pharmacol (1982) 0.75
Gaining access to the cytosol: the technique and some applications of electropermeabilization. Biochem J (1986) 3.00
Hereditary angioedema: its diagnostic and management perspectives. Am J Med (1990) 2.50
A habitable fluvio-lacustrine environment at Yellowknife Bay, Gale crater, Mars. Science (2013) 2.50
Spina bifida outcome: a 25-year prospective. Pediatr Neurosurg (2001) 2.38
Introducing a drug formulary to general practice--effects on practice prescribing costs. J R Coll Gen Pract (1987) 2.24
Quantitative evaluation of a screening program. Am J Public Health (1974) 2.00
The interaction of metal ions with ribulose 1,5-diphosphate carboxylase from spinach. J Biol Chem (1970) 1.94
Increased MCP-1, RANTES, and MIP-1alpha in bronchoalveolar lavage fluid of allergic asthmatic patients. Am J Respir Crit Care Med (1996) 1.75
Contribution of general practitioner hospitals in Scotland. Br Med J (Clin Res Ed) (1984) 1.74
Histamine-releasing activity (HRA). I. Production by mitogen- or antigen-stimulated human mononuclear cells. J Immunol (1979) 1.72
A closer look at water-related geologic activity on Mars. Science (2007) 1.71
Monocyte chemotactic and activating factor is a potent histamine-releasing factor for basophils. J Clin Invest (1992) 1.66
Volatile and organic compositions of sedimentary rocks in Yellowknife Bay, Gale crater, Mars. Science (2013) 1.65
The presence and possible role of zinc in RNA polymerase obtained from Escherichia coli. Proc Natl Acad Sci U S A (1971) 1.63
Community hospitals--time to come off the fence. J R Coll Gen Pract (1989) 1.57
Nucleotide sequence of the virulent SA-14 strain of Japanese encephalitis virus and its attenuated vaccine derivative, SA-14-14-2. Virology (1990) 1.52
Hydrated silicate minerals on Mars observed by the Mars Reconnaissance Orbiter CRISM instrument. Nature (2008) 1.52
Refractory cholinergic urticaria successfully treated with ketotifen. J Allergy Clin Immunol (1989) 1.52
Eotaxin induces degranulation and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen-activated protein kinases. Blood (2000) 1.51
RANTES is a chemotactic and activating factor for human eosinophils. J Immunol (1993) 1.49
Genetic variation among dengue 2 viruses of different geographic origin. Virology (1983) 1.48
Respiratory viruses induce production of histamine-releasing factor by mononuclear leukocytes: a possible role in the mechanism of virus-induced asthma. J Infect Dis (1991) 1.43
Cyclic nucleotides control a system which regulates Ca2+ sensitivity of platelet secretion. Nature (1984) 1.41
Monstrous, crablike hypertrophy of the cerebellar vermis and its relationship with Lhermitte-Duclos disease. Case report. J Neurosurg (1996) 1.39
A possible role for acetyl CoA in the control of gluconeogenesis. Adv Enzyme Regul (1964) 1.37
Pyruvate carboxylase. IX. Some properties of the activation by certain acyl derivatives of coenzyme A. J Biol Chem (1967) 1.37
Studies on gel-filtered human platelets: isolation and characterization in a medium containing no added Ca2+, Mg2+, or K+. J Lab Clin Med (1975) 1.36
Partial nucleotide sequence of St. Louis encephalitis virus RNA: structural proteins, NS1, ns2a, and ns2b. Virology (1987) 1.34
Thrombin and activators of protein kinase C modulate secretory responses of permeabilised human platelets induced by Ca2+. Eur J Biochem (1984) 1.28
Macrophage inflammatory protein-1 alpha activates basophils and mast cells. J Exp Med (1992) 1.27
Pyruvate carboxylase. V. Interaction of the enzyme with adenosine triphosphate. J Biol Chem (1965) 1.27
The sub-cellular localisation of pyruvate carboxylase and of some other enzymes in Aspergillus nidulans. Eur J Biochem (1983) 1.26
Characterization and myocarditic capabilities of coxsackievirus B3 variants in selected mouse strains. J Virol (1984) 1.26
The intrinsic helix-forming tendency of L-alanine. Proc Natl Acad Sci U S A (1992) 1.26
Complement-mediated release of histamine from human leukocytes. J Immunol (1975) 1.20
Agonist selectivity and second messenger concentration in Ca2+-mediated secretion. Nature (1982) 1.19
Personal accounts of the role of God in health and illness among older rural African American and White residents. J Cross Cult Gerontol (2000) 1.17
Copper infusion therapy in trichopoliodystrophy. J Pediatr (1975) 1.17
Direct evidence for a role for Ca2+ in amine storage granule secretion by human platelets. Thromb Res (1980) 1.17
Pyruvate carboxylase. Inhibition of the mammalian and avian liver enzymes by alpha-ketoglutarate and L-glutamate. J Biol Chem (1974) 1.17
Histamine-releasing activity (HRA). II. Interaction with basophils and physicochemical characterization. J Immunol (1979) 1.15
Early, reversible plasma membrane injury in galactosamine-induced liver cell death. Am J Pathol (1975) 1.14
The sub-cellular localisation and regulatory properties of pyruvate carboxylase from Rhizopus arrhizus. Eur J Biochem (1985) 1.14
Elemental geochemistry of sedimentary rocks at Yellowknife Bay, Gale crater, Mars. Science (2013) 1.14
Pyruvate carboxylase from chicken liver. Steady state kinetic studies indicate a "two-site" ping-pong mechanism. J Biol Chem (1972) 1.13
Genetic variation and microevolution of dengue 2 virus in Southeast Asia. Virology (1989) 1.13
Spinal lipomas in children: outcome of 270 procedures. Pediatr Neurosurg (1997) 1.11
Interaction of selective alpha-adrenoceptor agonists and antagonists with human and rabbit blood platelets. Br J Pharmacol (1980) 1.10
The role of cytoplasmic free calcium in the responses of quin2-loaded human platelets to vasopressin. Biochem J (1984) 1.09
Expression of high-affinity IgE receptors (Fc epsilon RI) on peripheral blood basophils, monocytes, and eosinophils in atopic and nonatopic subjects: relationship to total serum IgE concentrations. J Allergy Clin Immunol (1997) 1.08
Geographic classification of dengue-2 virus strains by antigen signature analysis. Virology (1986) 1.08
Mindfulness meditation-related pain relief: evidence for unique brain mechanisms in the regulation of pain. Neurosci Lett (2012) 1.08
'Idiopathic' nephrotic syndrome is not always idiopathic. Tex Med (1990) 1.07
Complement-mediated release of histamine from human basophils. II. Biochemical characterization of the reaction. J Immunol (1976) 1.05
In situ radiometric and exposure age dating of the martian surface. Science (2013) 1.03
The Opportunity Rover's Athena science investigation at Meridiani Planum, Mars. Science (2004) 1.03
Content and thrombin-induced release of acid hydrolases in gel-filtered platelets from patients with storage pool disease. Blood (1975) 1.02
Isolation and characterization of pyruvate carboxylase from Azotobacter vinelandii OP. Arch Biochem Biophys (1974) 1.02
NADPH generation in Aspergillus nidulans: is the mannitol cycle involved? J Gen Microbiol (1988) 1.02
High-affinity IgE receptor (FcepsilonRI)-bearing cells in bronchial biopsies from atopic and nonatopic asthma. Am J Respir Crit Care Med (1996) 1.02
Pyruvate carboxylase from Aspergillus nidulans. Regulatory properties. Eur J Biochem (1981) 1.00
Effects of guanine nucleotides on the properties of 5-hydroxytryptamine secretion from electropermeabilised human platelets. Eur J Biochem (1986) 1.00
Pyruvate carboxylase. VII. A possible role for tightly bound manganese. J Biol Chem (1966) 1.00
Epinephrine induces platelet fibrinogen receptor expression, fibrinogen binding, and aggregation in whole blood in the absence of other excitatory agonists. Blood (1989) 1.00
Partial amino acid sequences of chicken and turkey immunoglobulin light chains. Homology with mammalian lambda chains. Biochemistry (1971) 0.99
Cellular origin of histamine-releasing factor produced by peripheral blood mononuclear cells. J Immunol (1989) 0.98
A comparison of New World alphaviruses in the western equine encephalomyelitis complex by immunochemical and oligonucleotide fingerprint techniques. J Gen Virol (1980) 0.98
Release of slow reacting substance of anaphylaxis from human leukocytes. J Immunol (1974) 0.97
Positive interaction between agonists in the aggregation response of human blood platelets: interation between ADP, adrenaline and vasopressin. Br J Haematol (1980) 0.95
Pyruvate carboxylase. X. The demonstration of direct coordination of pyruvate and alpha-ketobutyrate by the bound manganese and the formation of enzyme-metal-substrate bridge complexes. Biochemistry (1967) 0.94
An assay system for localisation of pyruvate and phosphoenolpyruvate carboxylase activity on polyacrylamide gels and its application to detection of these enzymes in tissue and cell extracts. Anal Biochem (1975) 0.94
Pyruvate carboxylase from a thermophilic Bacillus. Studies on the specificity of activation by acyl derivatives of coenzyme A and on the properties of catalysis in the absence of activator. Biochem J (1978) 0.94
Pyruvate carboxylase from chicken liver. Effects of univalent and divalent cations on catalytic activity. J Biol Chem (1974) 0.94
Effect of various excitatory agonists on the secretion of 5-hydroxytryptamine from permeabilised human platelets induced by Ca2+ in the presence or absence of GTP. FEBS Lett (1985) 0.93
Pyruvate carboxylase from baker's yeast. The presence of bound zinc. J Biol Chem (1970) 0.93
The Spirit Rover's Athena science investigation at Gusev Crater, Mars. Science (2004) 0.92
Generation of slow reacting substance by human leukocytes. II. Comparison of stimulation by antigen, anti-IgE, calcium ionophore, and C5-peptide. J Immunol (1980) 0.92
Unsuspected benzyl alcohol hypersensitivity. N Engl J Med (1982) 0.92
Inhibitory effects of histidine and their reversal. The roles of pyruvate carboxylase and N10-formyltetrahydrofolate dehydrogenase. Biochem J (1979) 0.92
Pyruvate carboxylase. 8. The subunit structure as examined by electron microscopy. Biochemistry (1966) 0.92
Hyaluronic acid enhances cell proliferation during eosinopoiesis through the CD44 surface antigen. J Immunol (1995) 0.91
Synthesis of tentoxin and related dehydro cyclic tetrapeptides. J Org Chem (1978) 0.91
Beta-adrenoceptor antagonists and human platelets: relationship of effects to lipid solubility. Biochem Pharmacol (1984) 0.91
Interaction of human blood platelets with the 2',3'-dialdehyde and 2',3'-dialcohol derivatives of adenosine 5'-diphosphate and adenosine 5'-triphosphate. Eur J Biochem (1978) 0.90
Platelet beta-adrenoceptors. Br J Pharmacol (1983) 0.90
Pyruvate carboxylase from rat liver: catalytic properties in the absence, and at low concentrations, of acetyl-CoA. Biochem Biophys Res Commun (1972) 0.89
Mammalian platelet adrenoceptors. Br J Pharmacol (1984) 0.89
Dihydroergocryptine is a non-selective antagonist for human platelet alpha-adrenoreceptors. Nature (1979) 0.89
N-terminal sequence heterogeneity of guinea pig anti-DNP kappa chains. Immunochemistry (1969) 0.88
Fine control of the conversion of pyruvate (phosphoenolypyruvate) to oxaloacetate in various species. FEBS Lett (1978) 0.88
Estimating educational casualty from the 1964 rubella epidemic in Maryland. Md State Med J (1972) 0.88
Histamine-releasing activity. IV. Molecular heterogeneity of the activity from stimulated human thoracic duct lymphocytes. Cell Immunol (1984) 0.88
Pyruvate carboxylase from chicken liver: effects of sulfate and other anions on catalytic activity and structural parameters. Arch Biochem Biophys (1972) 0.88
Metal ion contents of gel-filtered platelets from patients with storage pool disease. Blood (1975) 0.88
Possible regulatory factors for pyruvate carboxylase with particular reference to enzyme from chicken liver. Metabolism (1971) 0.88
Identification of a histamine release inhibitory factor produced by human mononuclear cells in vitro. J Clin Invest (1988) 0.87