Published in Cold Spring Harb Symp Quant Biol on January 01, 1986
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Nested chromosomal fragmentation in yeast using the meganuclease I-Sce I: a new method for physical mapping of eukaryotic genomes. Nucleic Acids Res (1992) 1.27
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Control of partial digestion combining the enzymes dam methylase and MboI. Nucleic Acids Res (1989) 1.14
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A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif. Nature (1990) 10.97
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Nucleotide sequence of cdna coding for Semliki Forest virus membrane glycoproteins. Nature (1980) 8.07
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo. Cell (1997) 7.59
X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions. Nat Genet (1998) 6.82
Rapid restriction mapping of DNA cloned in lambda phage vectors. Gene (1984) 6.25
An integrated and simplified approach to cloning into plasmids and single-stranded phages. Methods Enzymol (1983) 5.81
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Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping. Nature (1990) 5.13
Imprinted expression of the Igf2r gene depends on an intronic CpG island. Nature (1997) 5.08
Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. EMBO Rep (2000) 5.06
Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Nature (1999) 5.03
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Normalization strategies for cDNA microarrays. Nucleic Acids Res (2000) 4.61
The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein. Nat Genet (1996) 4.59
Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology. Proc Natl Acad Sci U S A (1999) 4.58
Imprint switching on human chromosome 15 may involve alternative transcripts of the SNRPN gene. Nat Genet (1996) 4.36
Cloning of the T gene required in mesoderm formation in the mouse. Nature (1990) 4.20
DNA sequence and comparative analysis of chimpanzee chromosome 22. Nature (2004) 4.12
Selective isolation of cosmid clones by homologous recombination in Escherichia coli. Proc Natl Acad Sci U S A (1984) 4.11
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Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium. Nature (2000) 3.61
High resolution cosmid and P1 maps spanning the 14 Mb genome of the fission yeast S. pombe. Cell (1993) 3.56
The complete nucleotide sequence of chromosome 3 of Plasmodium falciparum. Nature (1999) 3.44
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The capsid protein of Semliki Forest virus has clusters of basic amino acids and prolines in its amino-terminal region. Proc Natl Acad Sci U S A (1980) 3.26
Derivation of clones close to met by preparative field inversion gel electrophoresis. Science (1987) 3.21
Covalent attachment of DNA to agarose. Improved synthesis and use in affinity chromatography. Eur J Biochem (1975) 3.18
Divalent cation regulation of the function of the leukocyte integrin LFA-1. J Cell Biol (1992) 3.07
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Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Nature (2002) 2.59
Construction and use of human chromosome jumping libraries from NotI-digested DNA. Nature (1987) 2.58
Conservation of microstructure between a sequenced region of the genome of rice and multiple segments of the genome of Arabidopsis thaliana. Genome Res (2001) 2.56
Molecular clones of the mouse t complex derived from microdissected metaphase chromosomes. Cell (1984) 2.55
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Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism. Nature (1994) 2.49
A complete BAC-based physical map of the Arabidopsis thaliana genome. Nat Genet (1999) 2.47
Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster. Hum Mol Genet (2001) 2.46
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Genetic analysis of the proximal portion of the mouse t complex: evidence for a second inversion within t haplotypes. Cell (1986) 2.40
Procollagen complementary DNA, a probe for messenger RNA purification and the number of type I collagen genes. Biochemistry (1978) 2.37
Dickkopf genes are co-ordinately expressed in mesodermal lineages. Mech Dev (1999) 2.36
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Primer design for large scale sequencing. Nucleic Acids Res (1998) 2.31
Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease. Hum Mol Genet (2001) 2.29
A regular pattern of two types of 100-residue motif in the sequence of titin. Nature (1990) 2.29
Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts. Oncogene (1999) 2.27
Clustering of multiallele DNA markers near the Huntington's disease gene. J Clin Invest (1989) 2.25
Identification and classification of differentially expressed genes in renal cell carcinoma by expression profiling on a global human 31,500-element cDNA array. Genome Res (2001) 2.25
Huntington disease-linked locus D4S111 exposed as the alpha-L-iduronidase gene. Somat Cell Mol Genet (1991) 2.23
Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells. Nat Genet (2000) 2.22
Interleukin-15 protects from lethal apoptosis in vivo. Nat Med (1997) 2.22
Construction, arraying, and high-density screening of large insert libraries of human chromosomes X and 21: their potential use as reference libraries. Proc Natl Acad Sci U S A (1991) 2.21