Published in J Virol on March 01, 1986
Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors. J Virol (1996) 6.22
Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis. J Virol (1996) 5.94
Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies. J Cell Biol (1995) 2.93
Adenovirus early region 4 encodes two gene products with redundant effects in lytic infection. J Virol (1989) 2.91
Redundant control of adenovirus late gene expression by early region 4. J Virol (1989) 2.83
Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery. J Virol (2002) 2.31
Analysis of adenovirus early region 4-encoded polypeptides synthesized in productively infected cells. J Virol (1987) 2.20
Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells. J Virol (1997) 2.09
Recruitment of wild-type and recombinant adeno-associated virus into adenovirus replication centers. J Virol (1996) 1.86
A gene transfer vector-cell line system for complete functional complementation of adenovirus early regions E1 and E4. J Virol (1996) 1.84
Deletion of the E4 region of the genome produces adenovirus DNA concatemers. Proc Natl Acad Sci U S A (1994) 1.84
Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication. J Virol (2005) 1.63
Cellular mRNA translation is blocked at both initiation and elongation after infection by influenza virus or adenovirus. J Virol (1986) 1.59
Adenovirus type 9 E4 open reading frame 1 encodes a transforming protein required for the production of mammary tumors in rats. J Virol (1994) 1.54
Human adenovirus encodes two proteins which have opposite effects on accumulation of alternatively spliced mRNAs. Mol Cell Biol (1994) 1.54
Adenovirus type 5 E4 open reading frame 4 protein induces apoptosis in transformed cells. J Virol (1998) 1.54
Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes. J Virol (2005) 1.50
Efficient dual transcomplementation of adenovirus E1 and E4 regions from a 293-derived cell line expressing a minimal E4 functional unit. J Virol (1996) 1.50
Adenovirus early region 4 is essential for normal stability of late nuclear RNAs. J Virol (1989) 1.47
Structural analysis of the adenovirus type 5 E1B 55-kilodalton-E4orf6 protein complex. J Virol (1997) 1.44
Adenovirus ubiquitin-protein ligase stimulates viral late mRNA nuclear export. J Virol (2006) 1.37
Transforming potential of the adenovirus type 5 E4orf3 protein. J Virol (1999) 1.31
Activation of RNA polymerase III transcription of human Alu repetitive elements by adenovirus type 5: requirement for the E1b 58-kilodalton protein and the products of E4 open reading frames 3 and 6. Mol Cell Biol (1993) 1.27
Adenovirus E4-dependent activation of the early E2 promoter is insufficient to promote the early-to-late-phase transition. J Virol (1991) 1.24
Adenovirus E4 open reading frame 4 protein autoregulates E4 transcription by inhibiting E1A transactivation of the E4 promoter. J Virol (1996) 1.24
Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses. J Virol (1997) 1.23
The adenovirus E1b55K/E4orf6 complex induces degradation of the Bloom helicase during infection. J Virol (2010) 1.15
Adenovirus early region 1A modulation of interferon antiviral activity. J Virol (1987) 1.12
Adenovirus early region 4 is required for efficient virus particle assembly. J Virol (1987) 1.11
Adenovirus E4 ORF3 protein inhibits the interferon-mediated antiviral response. J Virol (2007) 1.11
Control of mRNA export by adenovirus E4orf6 and E1B55K proteins during productive infection requires E4orf6 ubiquitin ligase activity. J Virol (2008) 1.11
Gene product of region E4 of adenovirus type 5 modulates accumulation of certain viral polypeptides. J Virol (1988) 1.09
Complementation of adenovirus E4 mutants by transient expression of E4 cDNA and deletion plasmids. Nucleic Acids Res (1989) 1.08
Regulated splicing of adenovirus type 5 E4 transcripts and regulated cytoplasmic accumulation of E4 mRNA. J Virol (1993) 1.07
Temporal regulation of the Mre11-Rad50-Nbs1 complex during adenovirus infection. J Virol (2009) 1.04
The NFIII/OCT-1 binding site stimulates adenovirus DNA replication in vivo and is functionally redundant with adjacent sequences. J Virol (1993) 1.03
The tripartite leader sequence of subgroup C adenovirus major late mRNAs can increase the efficiency of mRNA export. J Virol (1998) 1.03
The E4orf6/E1B55K E3 ubiquitin ligase complexes of human adenoviruses exhibit heterogeneity in composition and substrate specificity. J Virol (2010) 1.03
mRNA export correlates with activation of transcription in human subgroup C adenovirus-infected cells. J Virol (1996) 1.02
Distinct requirements of adenovirus E1b55K protein for degradation of cellular substrates. J Virol (2008) 1.01
Adenovirus late gene expression does not require a Rev-like nuclear RNA export pathway. J Virol (2000) 0.99
Role of adenovirus type 2 early region 4 in the early-to-late switch during productive infection. J Virol (1986) 0.98
Adenovirus early region 4 stimulates mRNA accumulation via 5' introns. Proc Natl Acad Sci U S A (1990) 0.96
RNA-binding activity of the E1B 55-kilodalton protein from human adenovirus type 5. J Virol (1998) 0.91
Overexpression of cyclin A inhibits augmentation of recombinant adeno-associated virus transduction by the adenovirus E4orf6 protein. J Virol (1999) 0.90
Intranuclear location of the adenovirus type 5 E1B 55-kilodalton protein. J Virol (1990) 0.88
Functional analysis of the adenovirus type 5 DNA-binding protein: site-directed mutants which are defective for adeno-associated virus helper activity. J Virol (1986) 0.87
Defective synthesis of early region 4 mRNAs during abortive adenovirus infections in monkey cells. J Virol (1992) 0.86
A proteomic approach to identify candidate substrates of human adenovirus E4orf6-E1B55K and other viral cullin-based E3 ubiquitin ligases. J Virol (2009) 0.86
Prospects for oral replicating adenovirus-vectored vaccines. Vaccine (2013) 0.86
Characterization of the recombinant adenovirus vector AdYB-1: implications for oncolytic vector development. J Virol (2006) 0.84
The adenovirus E1B 55-kilodalton and E4 open reading frame 6 proteins limit phosphorylation of eIF2alpha during the late phase of infection. J Virol (2009) 0.83
The structure and functions of the adenovirus early region 1 proteins. Biochem J (1987) 0.83
Adenovirus E4-ORF3-dependent relocalization of TIF1α and TIF1γ relies on access to the Coiled-Coil motif. Virology (2011) 0.83
The kinase activity of ataxia-telangiectasia mutated interferes with adenovirus E4 mutant DNA replication. J Virol (2013) 0.81
Adenovirus homologous recombination does not require expression of the immediate-early E1a gene. J Virol (1991) 0.81
Aggresome formation by the adenoviral protein E1B55K is not conserved among adenovirus species and is not required for efficient degradation of nuclear substrates. J Virol (2013) 0.80
Interaction of adenovirus type 5 E4orf4 with the nuclear pore subunit Nup205 is required for proper viral gene expression. J Virol (2014) 0.78
Differential activation of cellular DNA damage responses by replication-defective and replication-competent adenovirus mutants. J Virol (2012) 0.77
Isolation, identification, and complete genome sequence of a bovine adenovirus type 3 from cattle in China. Virol J (2011) 0.75
The Adenovirus E4orf4 Protein Provides a Novel Mechanism for Inhibition of the DNA Damage Response. PLoS Pathog (2016) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. J Mol Biol (1977) 205.11
A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels. Eur J Biochem (1974) 113.22
Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol (1977) 41.93
Method for detection of specific RNAs in agarose gels by transfer to diazobenzyloxymethyl-paper and hybridization with DNA probes. Proc Natl Acad Sci U S A (1977) 40.24
Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase. Proc Natl Acad Sci U S A (1981) 22.21
Spliced segments at the 5' terminus of adenovirus 2 late mRNA. Proc Natl Acad Sci U S A (1977) 14.34
Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells. Cell (1979) 10.95
Identification of procollagen mRNAs transferred to diazobenzyloxymethyl paper from formaldehyde agarose gels. Nucleic Acids Res (1979) 9.33
Identification of a protein linked to the ends of adenovirus DNA. Cell (1977) 7.21
Nucleotide sequences from the adenovirus-2 genome. J Biol Chem (1982) 5.76
Regulation of adenovirus-2 gene expression at the level of transcriptional termination and RNA processing. Nature (1981) 4.46
Expression of early adenovirus genes requires a viral encoded acidic polypeptide. Proc Natl Acad Sci U S A (1981) 4.42
Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff. J Virol (1985) 4.35
Isolation of deletion and substitution mutants of adenovirus type 5. Cell (1978) 4.29
Complete transformation by adenovirus 2 requires both E1A proteins. Cell (1984) 3.80
Identification of the gene and mRNA for the adenovirus terminal protein precursor. Cell (1981) 3.39
Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells. J Virol (1984) 3.38
Nucleotide sequence of adenovirus 2 DNA fragment encoding for the carboxylic region of the fiber protein and the entire E4 region. Nucleic Acids Res (1981) 3.31
Transcripts from the adenovirus-2 major late promoter yield a single early family of 3' coterminal mRNAs and five late families. Cell (1980) 3.21
DNA replication and the early to late transition in adenovirus infection. Cell (1980) 3.17
Regulation of the primary expression of the early adenovirus transcription units. J Virol (1979) 2.92
A cell line that supports the growth of a defective early region 4 deletion mutant of human adenovirus type 2. Proc Natl Acad Sci U S A (1983) 2.83
Adenovirus type 5 early region 1b gene product is required for efficient shutoff of host protein synthesis. J Virol (1984) 2.82
Separation of the adenovirus terminal protein precursor from its associated DNA polymerase: role of both proteins in the initiation of adenovirus DNA replication. Proc Natl Acad Sci U S A (1982) 2.65
Regulation of early adenovirus transcription: a protein product of early region 2 specifically represses region 4 transcription. Proc Natl Acad Sci U S A (1980) 2.42
An adenovirus type 5 gene function required for initiation of viral DNA replication. Virology (1975) 2.40
Identification and characterization of an immunologically conserved adenovirus early region 11,000 Mr protein and its association with the nuclear matrix. J Mol Biol (1982) 2.36
Deletion mutants of adenovirus 2: isolation and initial characterization of virus carrying mutations near the right end of the viral genome. Virology (1981) 2.32
Adenovirus 2 Ip+ locus codes for a 19 kd tumor antigen that plays an essential role in cell transformation. Cell (1983) 2.01
mRNAs from human adenovirus 2 early region 4. J Virol (1984) 1.92
Characterization of the major mRNAs from adenovirus 2 early region 4 by cDNA cloning and sequencing. Nucleic Acids Res (1984) 1.69
Splice junctions in adenovirus 2 early region 4 mRNAs: multiple splice sites produce 18 to 24 RNAs. J Virol (1984) 1.55
Adenovirus type 2 late mRNA's: structural evidence for 3'-coterminal species. J Virol (1978) 1.37
Mapping of an adenovirus function involved in the inhibition of DNA degradation. J Virol (1982) 1.32
Evidence for an altered adenovirus DNA polymerase in cells infected with the mutant H5ts149. Proc Natl Acad Sci U S A (1983) 1.30
In vitro complementation as an assay for purification of adenovirus DNA replication proteins. Proc Natl Acad Sci U S A (1983) 1.25
Regulation of adenovirus gene expression. Curr Top Microbiol Immunol (1982) 1.16
Expression of adenovirus-2 early region 4: assignment of the early region 4 polypeptides to their respective mRNAs, using in vitro translation. J Virol (1982) 1.15
Independent mutations in Ad2ts111 cause degradation of cellular DNA and defective viral DNA replication. J Virol (1984) 1.06
Isolatin and characterization of a viable deletion mutant of adenovirus type 3. Virology (1980) 0.83
The measurement of dyspnea. Contents, interobserver agreement, and physiologic correlates of two new clinical indexes. Chest (1984) 5.19
Integrated simian virus 40 sequences in transformed cell DNA: analysis using restriction endonucleases. Proc Natl Acad Sci U S A (1976) 4.92
The large, oxygen-rich halos of star-forming galaxies are a major reservoir of galactic metals. Science (2011) 2.95
Identification of cellular proteins required for simian virus 40 DNA replication. J Biol Chem (1989) 2.84
Redundant control of adenovirus late gene expression by early region 4. J Virol (1989) 2.83
A cell line that supports the growth of a defective early region 4 deletion mutant of human adenovirus type 2. Proc Natl Acad Sci U S A (1983) 2.83
Deletion mutants of adenovirus 2: isolation and initial characterization of virus carrying mutations near the right end of the viral genome. Virology (1981) 2.32
Favorable effect of VEGF gene transfer on ischemic peripheral neuropathy. Nat Med (2000) 2.13
Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells. J Virol (1997) 2.09
Infectious RNA transcripts from full-length dengue virus type 2 cDNA clones made in yeast. J Virol (1997) 1.99
Interaction of adenoviral E4 and E1b products in late gene expression. Virology (1990) 1.84
Adenovirus E4 34k and E4 11k inhibit double strand break repair and are physically associated with the cellular DNA-dependent protein kinase. Virology (1999) 1.77
Reversal of experimental diabetic neuropathy by VEGF gene transfer. J Clin Invest (2001) 1.73
Properties of an adenovirus type 2 mutant, Ad2dl807, having a deletion near the right-hand genome terminus: failure to help AAV replication. Virology (1983) 1.69
Adenovirus early region 4 is essential for normal stability of late nuclear RNAs. J Virol (1989) 1.47
Adenovirus early region 4 and viral DNA synthesis. Virology (1993) 1.44
The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis. J Virol (1998) 1.39
Operator and promoter mutations affecting divergent transcription in the bio gene cluster of Escherichia coli. J Mol Biol (1975) 1.33
Adenovirus E4-dependent activation of the early E2 promoter is insufficient to promote the early-to-late-phase transition. J Virol (1991) 1.24
Adenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosis. J Virol (1996) 1.19
Structure of integrated simian virus 40 DNA in transformed mouse cells. J Mol Biol (1980) 1.16
A deletion mutation placing the galactokinase gene of Escherichia coli under control of the biotin promoter. Proc Natl Acad Sci U S A (1974) 1.15
Influence of diabetes mellitus on chronic inflammatory demyelinating polyneuropathy. Muscle Nerve (2000) 1.12
Adenovirus early region 4 is required for efficient virus particle assembly. J Virol (1987) 1.11
Characterization of adenovirus particles made by deletion mutants lacking the fiber gene. J Virol (1988) 1.07
Molecular cloning and characterization of a new receptor for galanin. FEBS Lett (1997) 1.03
Potent and selective peptide agonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro. Biochem Biophys Res Commun (2001) 1.03
Improvement in chronic ischemic neuropathy after intramuscular phVEGF165 gene transfer in patients with critical limb ischemia. Arch Neurol (2001) 1.00
A comprehensive collection of point mutations in the internal promoter of the adenoviral VAI gene. J Biol Chem (1987) 0.96
Early region 4 modulates adenovirus DNA replication by two genetically separable mechanisms. Virology (1997) 0.96
Genetic analysis of a potential zinc-binding domain of the adenovirus E4 34k protein. J Biol Chem (2000) 0.96
Point mutations in the regulatory region of the human adenoviral VAI gene. J Biol Chem (1983) 0.95
The metabolism of host RNAs in cells infected by an adenovirus E4 mutant. Virology (1991) 0.93
Selective, high affinity peptide antagonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro. J Med Chem (2001) 0.92
Upper limb predominant, multifocal chronic inflammatory demyelinating polyneuropathy. Muscle Nerve (1999) 0.87
Analogs of MTII, lactam derivatives of alpha-melanotropin, modified at the N-terminus, and their selectivity at human melanocortin receptors 3, 4, and 5. Biochem Biophys Res Commun (1999) 0.87
Structure-function studies on the cyclic peptide MT-II, lactam derivative of alpha-melanotropin. Peptides (1999) 0.86
Biotin regulatory (bir) mutations of Escherichia coli. J Bacteriol (1980) 0.86
Molecular analysis of a new splice variant of the human melanocortin-1 receptor. FEBS Lett (1999) 0.85
The median nerve terminal latency index in carpal tunnel syndrome: a clinical case selection study. Muscle Nerve (1999) 0.84
Analogs of lactam derivatives of alpha-melanotropin with basic and acidic residues. Biochem Biophys Res Commun (2000) 0.83
D-Fructose-1,6-diphosphatase of navy bean (Phaseolus vulgaris L.) leaves. Arch Biochem Biophys (1969) 0.83
Myasthenic crisis after resection of an isolated metastatic thymoma of the cervical spine. J Clin Neuromuscul Dis (1999) 0.83
Terminal latency index in the carpal tunnel syndrome. Muscle Nerve (1997) 0.80
Carpal tunnel syndrome. Arch Neurol (2000) 0.77
Treatment experience in patients with anti-myelin-associated glycoprotein neuropathy. Muscle Nerve (2001) 0.76
Effect of limb restraints on serum creatine phosphokinase activity in normal volunteers. Biol Psychiatry (1977) 0.75
Tax policy toward health insurance and the demand for medical services. J Health Econ (1987) 0.75
Homology-based cloning methods. Identification of the NPY Y2, Y4, and Y6 receptors. Methods Mol Biol (2000) 0.75
Ancillary tests for assessment of the reproductive system. Vet Clin North Am Food Anim Pract (1992) 0.75