Published in J Bacteriol on February 01, 1986
Shiga and Shiga-like toxins. Microbiol Rev (1987) 8.58
Cloning, sequencing, and expression of the Escherichia coli cytolethal distending toxin genes. Infect Immun (1994) 2.94
Comparison of the carbohydrate-binding specificities of cholera toxin and Escherichia coli heat-labile enterotoxins LTh-I, LT-IIa, and LT-IIb. Infect Immun (1988) 2.32
Variation in chemical properties and antigenic determinants among type II heat-labile enterotoxins of Escherichia coli. Infect Immun (1986) 1.52
Clonal structure and virulence factors in strains of Escherichia coli of the classic serogroup O55. Infect Immun (1996) 1.51
Purification and characterization of type II heat-labile enterotoxin of Escherichia coli. Infect Immun (1986) 1.51
Virulence properties and clonal structures of strains of Escherichia coli O119 serotypes. Infect Immun (1997) 1.48
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Virulence factors associated with cytotoxic necrotizing factor type two in bovine diarrheic and septicemic strains of Escherichia coli. J Clin Microbiol (1991) 1.23
Comparative analysis of the mucosal adjuvanticity of the type II heat-labile enterotoxins LT-IIa and LT-IIb. Infect Immun (2000) 1.19
Type II heat-labile enterotoxin-producing Escherichia coli isolated from animals and humans. Infect Immun (1988) 1.16
Molecular genetic analysis of ganglioside GD1b-binding activity of Escherichia coli type IIa heat-labile enterotoxin by use of random and site-directed mutagenesis. Infect Immun (1992) 1.16
Enterotoxin-based mucosal adjuvants alter antigen trafficking and induce inflammatory responses in the nasal tract. Infect Immun (2005) 1.15
Fusion of Escherichia coli heat-stable enterotoxin and heat-labile enterotoxin B subunit. J Bacteriol (1987) 1.10
Initial studies of the structural signal for extracellular transport of cholera toxin and other proteins recognized by Vibrio cholerae. Infect Immun (1995) 1.10
Type II heat-labile enterotoxin of Escherichia coli activates adenylate cyclase in human fibroblasts by ADP ribosylation. Infect Immun (1987) 1.09
Genes coding for enterotoxins and verotoxins in porcine Escherichia coli strains belonging to different O:K:H serotypes: relationship with toxic phenotypes. J Clin Microbiol (1997) 1.08
Activation of Escherichia coli heat-labile enterotoxins by native and recombinant adenosine diphosphate-ribosylation factors, 20-kD guanine nucleotide-binding proteins. J Clin Invest (1991) 1.08
Cloning, nucleotide sequence, and hybridization studies of the type IIb heat-labile enterotoxin gene of Escherichia coli. J Bacteriol (1989) 1.05
Recombinant antigen-enterotoxin A2/B chimeric mucosal immunogens differentially enhance antibody responses and B7-dependent costimulation of CD4(+) T cells. Infect Immun (2001) 1.02
Differential binding of Escherichia coli enterotoxins LT-IIa and LT-IIb and of cholera toxin elicits differences in apoptosis, proliferation, and activation of lymphoid cells. Infect Immun (2005) 1.02
Characterization of hybrid toxins produced in Escherichia coli by assembly of A and B polypeptides from type I and type II heat-labile enterotoxins. Infect Immun (1992) 0.95
A longitudinal study of Vero cytotoxin producing Escherichia coli in cattle calves in Sri Lanka. Epidemiol Infect (1993) 0.94
LT-IIc, a new member of the type II heat-labile enterotoxin family encoded by an Escherichia coli strain obtained from a nonmammalian host. Infect Immun (2010) 0.91
Virulence factors and biochemical characteristics of serotypes of Escherichia coli serogroup O29. J Clin Microbiol (1989) 0.88
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Type II heat-labile enterotoxins from 50 diverse Escherichia coli isolates belong almost exclusively to the LT-IIc family and may be prophage encoded. PLoS One (2012) 0.85
Cholera-like enterotoxins and Regulatory T cells. Toxins (Basel) (2010) 0.82
Characterization of receptor-mediated signal transduction by Escherichia coli type IIa heat-labile enterotoxin in the polarized human intestinal cell line T84. Infect Immun (2001) 0.81
The chromosomal nature of LT-II enterotoxins solved: a lambdoid prophage encodes both LT-II and one of two novel pertussis-toxin-like toxin family members in type II enterotoxigenic Escherichia coli. Pathog Dis (2016) 0.75
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Prevalence of adhesin and toxin genes in E. coli strains isolated from diarrheic and non-diarrheic pigs from smallholder herds in northern and eastern Uganda. BMC Microbiol (2016) 0.75
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Electrophoretic resolution of the "major outer membrane protein" of Escherichia coli K12 into four bands. FEBS Lett (1975) 26.78
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A reliable method for the recovery of DNA fragments from agarose and acrylamide gels. Anal Biochem (1981) 15.38
The enterotoxin plasmids of Escherichia coli. J Infect Dis (1974) 9.10
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Production of Shigella dysenteriae type 1-like cytotoxin by Escherichia coli. J Infect Dis (1982) 8.05
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Nucleotide sequence homology between the heat-labile enterotoxin gene of Escherichia coli and Vibrio cholerae deoxyribonucleic acid. J Bacteriol (1980) 3.89
Relationships among heat-labile enterotoxins of Escherichia coli and Vibrio cholerae. J Infect Dis (1974) 3.66
Immunological nonidentity of heat-labile enterotoxins from human and porcine enterotoxigenic Escherichia coli. Infect Immun (1981) 3.46
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The origin, structure, and pharmacological activity of botulinum toxin. Pharmacol Rev (1981) 2.91
Characterization of monoclonal antibodies that react with unique and cross-reacting determinants of cholera enterotoxin and its subunits. Infect Immun (1983) 2.52
Purification of cholera toxin and its subunits: new methods of preparation and the use of hypertoxinogenic mutants. Infect Immun (1978) 2.16
Versatile cloning vectors derived from the runaway-replication plasmid pKN402. Gene (1981) 2.14
The gene for type A streptococcal exotoxin (erythrogenic toxin) is located in bacteriophage T12. Infect Immun (1984) 1.72
Evidence that a new enterotoxin of Escherichia coli which activates adenylate cyclase in eucaryotic target cells is not plasmid mediated. Infect Immun (1983) 1.64
Isolation and characterization of hypertoxinogenic (htx) mutants of Escherichia coli KL320(pCG86). Infect Immun (1981) 1.46
Plasmid-chromosomal transition of genes important in staphylococcal enterotoxin B expression. Infect Immun (1981) 1.40
Effects of lincomycin and tetracycline on production and properties of enterotoxins of enterotoxigenic Escherichia coli. Infect Immun (1983) 1.11
Shiga and Shiga-like toxins. Microbiol Rev (1987) 8.58
Two toxin-converting phages from Escherichia coli O157:H7 strain 933 encode antigenically distinct toxins with similar biologic activities. Infect Immun (1986) 8.09
Shiga-like toxin-converting phages from Escherichia coli strains that cause hemorrhagic colitis or infantile diarrhea. Science (1984) 7.94
Cloning and sequencing of a Shiga-like toxin type II variant from Escherichia coli strain responsible for edema disease of swine. J Bacteriol (1988) 5.43
Characterization of monoclonal antibodies against Shiga-like toxin from Escherichia coli. Infect Immun (1985) 5.04
Studies on toxinogenesis in Vibrio cholerae. I. Isolation of mutants with altered toxinogenicity. J Infect Dis (1974) 4.02
Cloning and sequencing of the genes for Shiga toxin from Shigella dysenteriae type 1. J Bacteriol (1988) 3.98
Adherence of bacteria to heart valves in vitro. J Clin Invest (1975) 3.74
Cloning of Shiga-like toxin structural genes from a toxin converting phage of Escherichia coli. Science (1985) 3.66
Nucleotide sequence analysis of the structural genes for Shiga-like toxin I encoded by bacteriophage 933J from Escherichia coli. Microb Pathog (1987) 3.25
Studies on toxinogenesis in Vibrio cholerae. III. Characterization of nontoxinogenic mutants in vitro and in experimental animals. J Clin Invest (1975) 3.12
Characterization of hapR, a positive regulator of the Vibrio cholerae HA/protease gene hap, and its identification as a functional homologue of the Vibrio harveyi luxR gene. Mol Microbiol (1997) 3.06
Environmental and human isolates of Vibrio cholerae and Vibrio parahaemolyticus produce a Shigella dysenteriae 1 (Shiga)-like cytotoxin. Lancet (1984) 3.05
Iron-dependent regulation of diphtheria toxin and siderophore expression by the cloned Corynebacterium diphtheriae repressor gene dtxR in C. diphtheriae C7 strains. Infect Immun (1991) 2.93
Construction of vectors with the p15a replicon, kanamycin resistance, inducible lacZ alpha and pUC18 or pUC19 multiple cloning sites. Nucleic Acids Res (1990) 2.77
Genetic analysis of tox+ and tox- bacteriophages of Corynebacterium diphtheriae. J Virol (1969) 2.71
Characterization of monoclonal antibodies that react with unique and cross-reacting determinants of cholera enterotoxin and its subunits. Infect Immun (1983) 2.52
Conjugal transfer of a chromosomal gene determining production of enterotoxin in vibrio cholerae. Science (1975) 2.47
Campylobacter jejuni cytolethal distending toxin causes a G2-phase cell cycle block. Infect Immun (1998) 2.34
Characterization and genetic mapping of nontoxinogenic (tox) mutants of corynebacteriophage beta. J Virol (1976) 2.33
Comparison of the carbohydrate-binding specificities of cholera toxin and Escherichia coli heat-labile enterotoxins LTh-I, LT-IIa, and LT-IIb. Infect Immun (1988) 2.32
Membrane traffic and the cellular uptake of cholera toxin. Biochim Biophys Acta (1999) 2.27
Cloning, sequence, and footprint analysis of two promoter/operators from Corynebacterium diphtheriae that are regulated by the diphtheria toxin repressor (DtxR) and iron. J Bacteriol (1994) 2.19
Genetic mapping of mutations in independently isolated nontoxinogenic mutants of Vibrio cholerae. Infect Immun (1978) 1.98
Characterization of an iron-dependent regulatory protein (IdeR) of Mycobacterium tuberculosis as a functional homolog of the diphtheria toxin repressor (DtxR) from Corynebacterium diphtheriae. Infect Immun (1995) 1.92
Ganglioside structure dictates signal transduction by cholera toxin and association with caveolae-like membrane domains in polarized epithelia. J Cell Biol (1998) 1.90
Targeting of cholera toxin and Escherichia coli heat labile toxin in polarized epithelia: role of COOH-terminal KDEL. J Cell Biol (1995) 1.86
Enzymatic assay for gentamicin and related aminoglycoside antibiotics. J Infect Dis (1974) 1.83
Coordinate regulation of siderophore and diphtheria toxin production by iron in Corynebacterium diphtheriae. Microb Pathog (1990) 1.83
Characterization of a defective diphtheria toxin repressor (dtxR) allele and analysis of dtxR transcription in wild-type and mutant strains of Corynebacterium diphtheriae. Infect Immun (1991) 1.79
Resistance of Pseudomonas aeruginosa to gentamicin and related aminoglycoside antibiotics. Antimicrob Agents Chemother (1974) 1.77
Studies on toxinogenesis in Vibrio cholerae. II. An vitro test for enterotoxin production. Infect Immun (1974) 1.72
Synthesis and secretion of the plasmid-coded heat-labile enterotoxin of Escherichia coli in Vibrio cholerae. Science (1983) 1.70
In vivo formation of hybrid toxins comprising Shiga toxin and the Shiga-like toxins and role of the B subunit in localization and cytotoxic activity. Infect Immun (1989) 1.69
Genetic, enzymatic, and pathogenic studies of the iron superoxide dismutase of Campylobacter jejuni. Infect Immun (1994) 1.67
Purification and characterization of the diphtheria toxin repressor. Proc Natl Acad Sci U S A (1992) 1.66
Regulation of toxinogenesis in Corynebacterium diphtheriae. I. Mutations in bacteriophage beta that alter the effects of iron on toxin production. J Virol (1981) 1.65
Transcriptional control of the iron-responsive fxbA gene by the mycobacterial regulator IdeR. J Bacteriol (1999) 1.65
Evidence that a new enterotoxin of Escherichia coli which activates adenylate cyclase in eucaryotic target cells is not plasmid mediated. Infect Immun (1983) 1.64
Shiga-like toxin converting phage of enterohemorrhagic Escherichia coli strain 933. Microb Pathog (1989) 1.60
Regulation of toxinogenesis in Corynebacterium diphtheriae: mutations in the bacterial genome that alter the effects of iron on toxin production. J Bacteriol (1983) 1.60
Chemical and immunochemical studies on the receptor binding domain of cholera toxin B subunit. J Biol Chem (1985) 1.56
Identification and characterization of three new promoter/operators from Corynebacterium diphtheriae that are regulated by the diphtheria toxin repressor (DtxR) and iron. Infect Immun (1997) 1.55
Comparative studies with tox plus and tox minus corynebacteriophages. J Virol (1970) 1.55
Three-dimensional structure of the diphtheria toxin repressor in complex with divalent cation co-repressors. Structure (1995) 1.53
Genetic and biochemical evidence for a siderophore-dependent iron transport system in Corynebacterium diphtheriae. Infect Immun (1984) 1.53
Variation in chemical properties and antigenic determinants among type II heat-labile enterotoxins of Escherichia coli. Infect Immun (1986) 1.52
Purification and characterization of type II heat-labile enterotoxin of Escherichia coli. Infect Immun (1986) 1.51
Analysis of structure and function of the B subunit of cholera toxin by the use of site-directed mutagenesis. Mol Microbiol (1991) 1.50
Analysis of diphtheria toxin repressor-operator interactions and characterization of a mutant repressor with decreased binding activity for divalent metals. Mol Microbiol (1993) 1.49
Iron regulation of the cloned diphtheria toxin promoter in Escherichia coli. Infect Immun (1988) 1.48
High-resolution structure of the diphtheria toxin repressor complexed with cobalt and manganese reveals an SH3-like third domain and suggests a possible role of phosphate as co-corepressor. Biochemistry (1996) 1.47
Isolation and characterization of hypertoxinogenic (htx) mutants of Escherichia coli KL320(pCG86). Infect Immun (1981) 1.46
Effects of DNase production, plasmid size, and restriction barriers on transformation of Vibrio cholerae by electroporation and osmotic shock. FEMS Microbiol Lett (1990) 1.46
Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain. J Mol Biol (1999) 1.46
Crystal structure of a new heat-labile enterotoxin, LT-IIb. Structure (1996) 1.42
Effects of iron and temperature on Shiga-like toxin I production by Escherichia coli. Infect Immun (1988) 1.40
Characterization and presumptive identification of Helicobacter pylori isolates from rhesus monkeys. J Clin Microbiol (1994) 1.39
Transcription of the Shiga-like toxin type II and Shiga-like toxin type II variant operons of Escherichia coli. J Bacteriol (1990) 1.39
Characterization of mutations that inactivate the diphtheria toxin repressor gene (dtxR). Infect Immun (1994) 1.38
Production of type II heat-labile enterotoxin by Escherichia coli isolated from food and human feces. Infect Immun (1986) 1.35
Quantitative assay of diphtherial toxin and of immunologically cross-reacting proteins by reversed passive hemagglutination. Infect Immun (1975) 1.33
Radial passive immune hemolysis assay for detection of heat-labile enterotoxin produced by individual colonies of Escherichia coli or Vibrio cholerae. J Clin Microbiol (1978) 1.33
Crystal structure of the iron-dependent regulator (IdeR) from Mycobacterium tuberculosis shows both metal binding sites fully occupied. J Mol Biol (1999) 1.32
Immunochemical studies of diphtherial toxin and related nontoxic mutant proteins. Infect Immun (1980) 1.32
Two fep genes are required for ferrienterochelin uptake in Escherichia coli K-12. J Bacteriol (1983) 1.31
A Campylobacter jejuni homolog of the LcrD/FlbF family of proteins is necessary for flagellar biogenesis. Infect Immun (1993) 1.26
Immunoprecipitation and partial characterization of diphtheria toxin-binding glycoproteins from surface of guinea pig cells. Proc Natl Acad Sci U S A (1979) 1.26
Characterization of monoclonal antibodies to heat-labile enterotoxin encoded by a plasmid from a clinical isolate of Escherichia coli. Infect Immun (1984) 1.25
Transferrable resistance to tobramycin in Klebsiella pneumoniae and Enterobacter cloacae associated with enzymatic acetylation of tobramycin. Antimicrob Agents Chemother (1974) 1.25
Functional analysis of the Shiga toxin and Shiga-like toxin type II variant binding subunits by using site-directed mutagenesis. J Bacteriol (1990) 1.24
The 1.25 A resolution refinement of the cholera toxin B-pentamer: evidence of peptide backbone strain at the receptor-binding site. J Mol Biol (1998) 1.24
Initial characterization of the ferric iron transport system of Corynebacterium diphtheriae. J Bacteriol (1983) 1.23
Cytolethal distending toxin demonstrates genotoxic activity in a yeast model. Infect Immun (2001) 1.23
Cyclic AMP-independent effects of cholera toxin on B cell activation. II. Binding of ganglioside GM1 induces B cell activation. J Immunol (1992) 1.21
Proteolytic activation of cholera toxin and Escherichia coli labile toxin by entry into host epithelial cells. Signal transduction by a protease-resistant toxin variant. J Biol Chem (1997) 1.18
Fusion proteins containing the A2 domain of cholera toxin assemble with B polypeptides of cholera toxin to form immunoreactive and functional holotoxin-like chimeras. Infect Immun (1992) 1.16
Molecular genetic analysis of ganglioside GD1b-binding activity of Escherichia coli type IIa heat-labile enterotoxin by use of random and site-directed mutagenesis. Infect Immun (1992) 1.16
Construction and characterization of versatile cloning vectors for efficient delivery of native foreign proteins to the periplasm of Escherichia coli. Plasmid (1997) 1.16
Crystal structure of the iron-dependent regulator from Mycobacterium tuberculosis at 2.0-A resolution reveals the Src homology domain 3-like fold and metal binding function of the third domain. J Biol Chem (2000) 1.15
Effects of divalent cations on binding of aminoglycoside antibiotics to human serum proteins and to bacteria. Antimicrob Agents Chemother (1975) 1.14
Cloning of extracellular DNase and construction of a DNase-negative strain of Vibrio cholerae. Infect Immun (1985) 1.14
Evidence for direct insertion of fragments A and B of diphtheria toxin into model membranes. J Biol Chem (1984) 1.13
Characterization of lipoprotein IRP1 from Corynebacterium diphtheriae, which is regulated by the diphtheria toxin repressor (DtxR) and iron. Infect Immun (1997) 1.13
Isolation and characterization of melanin-producing (mel) mutants of Vibrio cholerae. Infect Immun (1980) 1.12
Transposon-mediated mutagenesis and recombination in Vibrio cholerae. Infect Immun (1984) 1.12
Comparison of a radioimmunoassay with an enzymatic assay for gentamicin. Antimicrob Agents Chemother (1975) 1.12