Identification and characterization of a nuclear pore complex protein.

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex. J Cell Biol (1996) 7.64

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A (2004) 7.55

Proteomic analysis of the mammalian nuclear pore complex. J Cell Biol (2002) 6.38

Monoclonal antibodies identify a group of nuclear pore complex glycoproteins. J Cell Biol (1987) 5.79

Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores. J Cell Biol (1987) 5.62

Identification of different roles for RanGDP and RanGTP in nuclear protein import. EMBO J (1996) 5.53

Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. Proc Natl Acad Sci U S A (1995) 5.04

The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88. EMBO J (1997) 4.65

Identification and characterization of a yeast nucleolar protein that is similar to a rat liver nucleolar protein. J Cell Biol (1988) 4.42

Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope. J Cell Biol (1994) 4.25

The inner centromere protein (INCENP) antigens: movement from inner centromere to midbody during mitosis. J Cell Biol (1987) 4.05

Nuclear pore complex contains a family of glycoproteins that includes p62: glycosylation through a previously unidentified cellular pathway. Proc Natl Acad Sci U S A (1987) 3.95

Sequence and characterization of cytoplasmic nuclear protein import factor p97. J Cell Biol (1995) 3.85

Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine. J Cell Biol (1987) 3.73

A new family of yeast nuclear pore complex proteins. J Cell Biol (1992) 3.60

A new subclass of nucleoporins that functionally interact with nuclear pore protein NSP1. EMBO J (1992) 3.57

Nuclear envelope budding enables large ribonucleoprotein particle export during synaptic Wnt signaling. Cell (2012) 3.50

A temperature-sensitive mutation of the Schizosaccharomyces pombe gene nuc2+ that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase. J Cell Biol (1988) 3.28

Isolation of the yeast nuclear pore complex. J Cell Biol (1993) 3.27

A monoclonal antibody against the nuclear pore complex inhibits nucleocytoplasmic transport of protein and RNA in vivo. J Cell Biol (1988) 3.20

The human CAN protein, a putative oncogene product associated with myeloid leukemogenesis, is a nuclear pore complex protein that faces the cytoplasm. Proc Natl Acad Sci U S A (1994) 3.19

A conditional allele of the novel repeat-containing yeast nucleoporin RAT7/NUP159 causes both rapid cessation of mRNA export and reversible clustering of nuclear pore complexes. J Cell Biol (1995) 3.19

A temperature-sensitive NUP116 null mutant forms a nuclear envelope seal over the yeast nuclear pore complex thereby blocking nucleocytoplasmic traffic. J Cell Biol (1993) 3.07

AIR-2: An Aurora/Ipl1-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos. J Cell Biol (1998) 3.07

Purification of NSP1 reveals complex formation with 'GLFG' nucleoporins and a novel nuclear pore protein NIC96. EMBO J (1993) 3.04

Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration. J Cell Biol (2004) 3.01

A chemical approach for identifying O-GlcNAc-modified proteins in cells. Proc Natl Acad Sci U S A (2003) 2.97

Protein import through the nuclear pore complex is a multistep process. J Cell Biol (1989) 2.89

A complex of nuclear pore proteins required for pore function. J Cell Biol (1991) 2.87

HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection. Genes Dev (1998) 2.82

A size-exclusion permeability barrier and nucleoporins characterize a ciliary pore complex that regulates transport into cilia. Nat Cell Biol (2012) 2.81

A conserved biogenesis pathway for nucleoporins: proteolytic processing of a 186-kilodalton precursor generates Nup98 and the novel nucleoporin, Nup96. J Cell Biol (1999) 2.76

A visual screen of a GFP-fusion library identifies a new type of nuclear envelope membrane protein. J Cell Biol (1999) 2.69

Interactions and three-dimensional localization of a group of nuclear pore complex proteins. J Cell Biol (1994) 2.63

GLE2, a Saccharomyces cerevisiae homologue of the Schizosaccharomyces pombe export factor RAE1, is required for nuclear pore complex structure and function. Mol Biol Cell (1996) 2.60

Proteins connecting the nuclear pore complex with the nuclear interior. J Cell Biol (1999) 2.60

Dynamics of single mRNP nucleocytoplasmic transport and export through the nuclear pore in living cells. Nat Cell Biol (2010) 2.59

Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase. J Exp Med (2004) 2.55

Nuclear pore complex clustering and nuclear accumulation of poly(A)+ RNA associated with mutation of the Saccharomyces cerevisiae RAT2/NUP120 gene. J Cell Biol (1995) 2.54

Effects of poliovirus infection on nucleo-cytoplasmic trafficking and nuclear pore complex composition. EMBO J (2001) 2.47

NUP145 encodes a novel yeast glycine-leucine-phenylalanine-glycine (GLFG) nucleoporin required for nuclear envelope structure. J Cell Biol (1994) 2.46

Influenza virus targets the mRNA export machinery and the nuclear pore complex. Proc Natl Acad Sci U S A (2007) 2.44

Yeast nuclear envelope proteins cross react with an antibody against mammalian pore complex proteins. J Cell Biol (1989) 2.40

In vitro formation of the endoplasmic reticulum occurs independently of microtubules by a controlled fusion reaction. J Cell Biol (2000) 2.38

Genetic and physical interactions between Srp1p and nuclear pore complex proteins Nup1p and Nup2p. J Cell Biol (1994) 2.37

A mutant nuclear protein with similarity to RNA binding proteins interferes with nuclear import in yeast. Mol Biol Cell (1992) 2.33

Identification of protein p270/Tpr as a constitutive component of the nuclear pore complex-attached intranuclear filaments. J Cell Biol (1997) 2.32

An integral membrane protein of the pore membrane domain of the nuclear envelope contains a nucleoporin-like region. J Cell Biol (1993) 2.32

A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear export. J Cell Biol (1999) 2.27

Interactions and structure of the nuclear pore complex revealed by cryo-electron microscopy. J Cell Biol (1989) 2.26

Characterisation of the passive permeability barrier of nuclear pore complexes. EMBO J (2009) 2.21

A constitutive nucleolar protein identified as a member of the nucleoplasmin family. EMBO J (1987) 2.20

Stepwise reassembly of the nuclear envelope at the end of mitosis. J Cell Biol (1993) 2.17

G2 arrest and impaired nucleocytoplasmic transport in mouse embryos lacking the proto-oncogene CAN/Nup214. EMBO J (1996) 2.17

NUP2, a novel yeast nucleoporin, has functional overlap with other proteins of the nuclear pore complex. Mol Biol Cell (1993) 2.15

Integral membrane proteins specific to the inner nuclear membrane and associated with the nuclear lamina. J Cell Biol (1988) 2.15

Reconstituted nuclei depleted of a vertebrate GLFG nuclear pore protein, p97, import but are defective in nuclear growth and replication. J Cell Biol (1995) 2.11

Intranuclear filaments containing a nuclear pore complex protein. J Cell Biol (1993) 2.11

C. elegans nuclear envelope proteins emerin, MAN1, lamin, and nucleoporins reveal unique timing of nuclear envelope breakdown during mitosis. Mol Biol Cell (2000) 2.11

Herpes simplex virus type 1 entry into host cells: reconstitution of capsid binding and uncoating at the nuclear pore complex in vitro. Mol Cell Biol (2000) 2.10

Primary sequence and heterologous expression of nuclear pore glycoprotein p62. J Cell Biol (1990) 2.09

A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding. EMBO Rep (2008) 2.09

Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly. Mol Biol Cell (1997) 2.08

Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores. Mol Biol Cell (2003) 2.08

p34cdc2-mediated phosphorylation at T124 inhibits nuclear import of SV-40 T antigen proteins. J Cell Biol (1991) 2.08

The NUF1 gene encodes an essential coiled-coil related protein that is a potential component of the yeast nucleoskeleton. J Cell Biol (1992) 2.07

Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry. PLoS Biol (2010) 2.07

The cell cycle independence of HIV infections is not determined by known karyophilic viral elements. PLoS Pathog (2005) 2.02

A common maturation pathway for small nucleolar RNAs. EMBO J (1995) 2.02

Nup155 is a novel nuclear pore complex protein that contains neither repetitive sequence motifs nor reacts with WGA. J Cell Biol (1993) 1.98

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Identification of four nuclear transport signal-binding proteins that interact with diverse transport signals. Mol Cell Biol (1989) 1.97

Disruption of the nucleoporin gene NUP133 results in clustering of nuclear pore complexes. Proc Natl Acad Sci U S A (1995) 1.90

The matrix protein of vesicular stomatitis virus inhibits nucleocytoplasmic transport when it is in the nucleus and associated with nuclear pore complexes. Mol Cell Biol (2000) 1.89

Expression of the hepatitis B virus X gene in mammalian cells. Proc Natl Acad Sci U S A (1987) 1.88

Saccharomyces cerevisiae Ndc1p is a shared component of nuclear pore complexes and spindle pole bodies. J Cell Biol (1998) 1.87

Cofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin. J Cell Biol (2001) 1.86

HCP-4, a CENP-C-like protein in Caenorhabditis elegans, is required for resolution of sister centromeres. J Cell Biol (2001) 1.81

Transportin-SR2 mediates nuclear import of phosphorylated SR proteins. Proc Natl Acad Sci U S A (2001) 1.80

UNC-83 IS a KASH protein required for nuclear migration and is recruited to the outer nuclear membrane by a physical interaction with the SUN protein UNC-84. Mol Biol Cell (2006) 1.79

A nuclear localization signal binding protein in the nucleolus. J Cell Biol (1990) 1.78

Microinjected U snRNAs are imported to oocyte nuclei via the nuclear pore complex by three distinguishable targeting pathways. J Cell Biol (1992) 1.76

nup1 mutants exhibit pleiotropic defects in nuclear pore complex function. J Cell Biol (1994) 1.76

Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor. Mol Cell Proteomics (2009) 1.74

Visualization of transport-related configurations of the nuclear pore transporter. Biophys J (1990) 1.73

Resolution of anaphase bridges in cancer cells. Chromosoma (2004) 1.72

Interaction of the human immunodeficiency virus type 1 Vpr protein with the nuclear pore complex. J Virol (1998) 1.70

Yeast mitochondria contain ATP-sensitive, reversible actin-binding activity. Mol Biol Cell (1994) 1.65

The human homologue of Saccharomyces cerevisiae Gle1p is required for poly(A)+ RNA export. Proc Natl Acad Sci U S A (1998) 1.64

Assembly of the nuclear pore: biochemically distinct steps revealed with NEM, GTP gamma S, and BAPTA. J Cell Biol (1996) 1.63

SMG-1 is a phosphatidylinositol kinase-related protein kinase required for nonsense-mediated mRNA Decay in Caenorhabditis elegans. Mol Cell Biol (2004) 1.62

Lymphocyte activation induces rapid changes in nuclear and cytoplasmic glycoproteins. Proc Natl Acad Sci U S A (1991) 1.60

The single transmembrane segment of gp210 is sufficient for sorting to the pore membrane domain of the nuclear envelope. J Cell Biol (1992) 1.58

ER membrane-bending proteins are necessary for de novo nuclear pore formation. J Cell Biol (2009) 1.57

Extragenic suppressors of mutations in the cytoplasmic C terminus of SEC63 define five genes in Saccharomyces cerevisiae. Genetics (1993) 1.57

Modulation of transcription factor function by O-GlcNAc modification. Biochim Biophys Acta (2010) 1.55

Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1. J Cell Biol (2004) 1.54

EMB-30: an APC4 homologue required for metaphase-to-anaphase transitions during meiosis and mitosis in Caenorhabditis elegans. Mol Biol Cell (2000) 1.52

Evidence that poly(A) binding protein C1 binds nuclear pre-mRNA poly(A) tails. Mol Cell Biol (2006) 1.50

A monoclonal antibody against a family of nuclear pore proteins (nucleoporins): O-linked N-acetylglucosamine is part of the immunodeterminant. Proc Natl Acad Sci U S A (1987) 1.47

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The GTP-binding protein Ran/TC4 is required for protein import into the nucleus. Nature (1993) 7.80

Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum. Nature (1982) 7.80

The nuclear envelope lamina is reversibly depolymerized during mitosis. Cell (1980) 7.67

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex. J Cell Biol (1996) 7.64

Translocation of proteins across the endoplasmic reticulum. I. Signal recognition protein (SRP) binds to in-vitro-assembled polysomes synthesizing secretory protein. J Cell Biol (1981) 7.40

Purification of a membrane-associated protein complex required for protein translocation across the endoplasmic reticulum. Proc Natl Acad Sci U S A (1980) 7.17

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Preparation of microsomal membranes for cotranslational protein translocation. Methods Enzymol (1983) 6.94

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Immunocytochemical localization of the major polypeptides of the nuclear pore complex-lamina fraction. Interphase and mitotic distribution. J Cell Biol (1978) 6.29

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cDNA sequencing of nuclear lamins A and C reveals primary and secondary structural homology to intermediate filament proteins. Proc Natl Acad Sci U S A (1986) 5.07

Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. Proc Natl Acad Sci U S A (1995) 5.04

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The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J (1997) 4.80

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Identification and characterization of a yeast nucleolar protein that is similar to a rat liver nucleolar protein. J Cell Biol (1988) 4.42

The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export. Curr Biol (1997) 4.35

Tryptic dissection and reconstitution of translocation activity for nascent presecretory proteins across microsomal membranes. Proc Natl Acad Sci U S A (1979) 4.22

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Isolation and characterization of a proteinaceous subnuclear fraction composed of nuclear matrix, peripheral lamina, and nuclear pore complexes from embryos of Drosophila melanogaster. J Cell Biol (1982) 4.03

A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm. Cell (1993) 3.98

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A distinct nuclear import pathway used by ribosomal proteins. Cell (1997) 3.66

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A protein of molecular weight 78,000 bound to the polyadenylate region of eukaryotic messenger RNAs. Proc Natl Acad Sci U S A (1973) 3.38

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A lamin B receptor in the nuclear envelope. Proc Natl Acad Sci U S A (1988) 3.28

Cell-free synthesis of fish preproinsulin, and processing by heterologous mammalian microsomal membranes. Proc Natl Acad Sci U S A (1977) 3.27

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Isolation of components of the chloroplast protein import machinery. Science (1994) 3.24

The human CAN protein, a putative oncogene product associated with myeloid leukemogenesis, is a nuclear pore complex protein that faces the cytoplasm. Proc Natl Acad Sci U S A (1994) 3.19

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Two novel related yeast nucleoporins Nup170p and Nup157p: complementation with the vertebrate homologue Nup155p and functional interactions with the yeast nuclear pore-membrane protein Pom152p. J Cell Biol (1995) 2.95

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