Antiplatelet agents for chronic kidney disease.

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🔗 View Article (PMID 35224730)

Published in Cochrane Database Syst Rev on February 28, 2022


Patrizia Natale1,2,3, Suetonia C Palmer4, Valeria M Saglimbene1,2, Marinella Ruospo1,2, Mona Razavian5, Jonathan C Craig2,6, Meg J Jardine7, Angela C Webster2,8, Giovanni Fm Strippoli1,2,6

Author Affiliations

1: Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.
2: Sydney School of Public Health, The University of Sydney, Sydney, Australia.
3: Nephrology, Dialysis and Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
4: Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand.
5: Renal and Metabolic Division, The George Institute for Global Health, Newtown, Australia.
6: Cochrane Kidney and Transplant, Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, Australia.
7: NHMRC Clinical Trials Centre, Camperdown, Australia.
8: Centre for Transplant and Renal Research, Westmead Millennium Institute, The University of Sydney at Westmead, Westmead, Australia.

Associated clinical trials:

A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome (PLATO) | NCT00391872

Secondary Prevention of Small Subcortical Strokes Trial (SPS3) | NCT00059306

A Comparison of Prasugrel (CS-747) and Clopidogrel in Acute Coronary Syndrome Subjects Who Are to Undergo Percutaneous Coronary Intervention | NCT00097591

Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance (CHARISMA) | NCT00050817

Trial to Assess the Effects of Vorapaxar (SCH 530348; MK-5348) in Preventing Heart Attack and Stroke in Patients With Atherosclerosis (TRA 2°P - TIMI 50) (P04737) | NCT00526474

A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects (TRILOGY ACS) | NCT00699998

Intensified Multifactorial Intervention in Patients With Type 2 Diabetes and Microalbuminuria (Steno-2) | NCT00320008

Trial to Assess the Effects of Vorapaxar (SCH 530348; MK-5348) in Preventing Heart Attack and Stroke in Particpants With Acute Coronary Syndrome (TRA•CER) (Study P04736) | NCT00527943

A Phase III Study of Apixaban in Patients With Atrial Fibrillation (AVERROES) | NCT00496769

PeriOperative ISchemic Evaluation-2 Trial (POISE-2) | NCT01082874

Prevention of Cardiovascular Events (eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke) in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin (PEGASUS) | NCT01225562

Clopidogrel in High-risk Patients With Acute Non-disabling Cerebrovascular Events (CHANCE) | NCT00979589

Synergy Between Stent and Drugs to Avoid Ischemic Recurrences After Percutaneous Coronary Intervention (PRODIGY) | NCT00611286

Vascular Access Clinical Trials Data Coordinating Center | NCT00067119

EARLY ACS: Early Glycoprotein IIb/IIIa Inhibition in Patients With Non-ST-segment Elevation Acute Coronary Syndrome (Study P03684AM2)(COMPLETED) | NCT00089895

Japanese Primary Prevention of Atherosclerosis With Aspirin for Diabetes (JPAD) Trial | NCT00110448

Prospective Randomized Study Comparing Renal Artery Stenting (RESIST)With/Without Distal Protection | NCT00234585

The Efficacy of CILostazol ON Ischemic Complications After DES Implantation (CILON-T) | NCT00776828

TRK-100STP Clinical Study - Chronic Renal Failure (Primary Glomerular Disease/Nephrosclerosis) | NCT01090037

Effect of Platelet Inhibition According to Clopidogrel Dose in Patients With Chronic Kidney Disease (CKD) | NCT01328470

Stenting of Renal Artery Stenosis in Coronary Artery Disease Study (RASCAD) | NCT01173666

Ramipril and Clopidogrel in Oxidative Stress, Vascular Inflammation and Endothelial Dysfunction in Type 2 Diabetes and Diabetic Nephropathy | NCT01743014

Study Design of 'Influence of Sarpogrelate in Patients With Renal Impairment or Diabetes Mellitus' Study (SERENADE) | NCT02294643

The Prevention of Contrast Induced Nephropathy by Sarpogrelate in Patients With Chronic Kidney Disease | NCT01165567

Effect of Sarpogrelate On the Nephropathy in Type 2 Diabetes (SONATA Study) | NCT01869881

Primary Cardiovascular Risk Prevention With Aspirin in Chronic Kidney Disease Patients | NCT01709994

COmparison of the Pharmacodynamics and Pharmacokinetics Ticagrelor Versus Clopidogrel in Patients With CKD and NSTE-ACS (OPT-CKD) | NCT02578537

Platelet Resistance With Ticagrelor or Standard-Dose Clopidogrel Among CKD and ACS Patients (APROVE-CKD) | NCT02459288

Ticagrelor and Anti-inflammatory Effects | NCT02406911

Genotype and Platelet Reactivity in Patients on Hemodialysis | NCT02394145

ONSET and OFFSET of Ticagrelor in ESRD | NCT02163954

Pharmacokinetics, Pharmacodynamics, and Safety Study of Ticagrelor in Hemodialysis Patients and Healthy Subjects | NCT02022748

A Clinical Study to Evaluate the Efficacy and Safety of Cilostazol and Probucol in Combination on Patients With Diabetic Nephropathy | NCT01252056

Aspirin in the Prevention of Cardiovascular Events in Hemodialysis Patients | NCT01198379

Prasugrel Versus High Dose Clopidogrel in Clopidogrel Resistant Patients Undergoing Chronic Hemodialysis | NCT01155765

Platelet Aggregation in Patients With Coronary Artery Disease and Kidney Dysfunction Taking Clopidogrel or Ticagrelor | NCT03039205

Study Comparing Treatment Effectiveness of Guideline Indicated APT for ACS in Patients With CKD (CPRS-CKD) | NCT03150667

Clopidogrel Prevention of Early Arteriovenous (AV) Fistula Thrombosis (FISTULA) | NCT03289520

TicagRelor Or Clopidogrel in Severe and Terminal Chronic Kidney Disease Patients Undergoing PERcutaneous Coronary Intervention for an Acute Coronary Syndrome. (TROUPER) | NCT03357874

Low Dose Ticagrelor Versus Low Dose Prasugrel in Patients With Prior Myocardial Infarction (ALTIC-2) | NCT03387826

Chronic Kidney Disease (CKD) Platelet Study | NCT03649711

Aspirin to Target Arterial Events in Chronic Kidney Disease (ATTACK) | NCT03796156

Aspirin and Renal Disease Progression in Patients With Type 2 Diabetes (LEDA) | NCT02895113

A Randomized, Pharmacodynamic Comparison of Low Dose Ticagrelor to Clopidogrel in Patients With Prior Myocardial Infarction (ALTIC) | NCT02663713

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Healthy Dietary Patterns and Risk of Mortality and ESRD in CKD: A Meta-Analysis of Cohort Studies. Clin J Am Soc Nephrol (2016) 0.75

Prevention of contrast-induced acute kidney injury in patients undergoing cardiovascular procedures-a systematic review and network meta-analysis. PLoS One (2017) 0.75

Low versus high dose erythropoiesis-stimulating agents in hemodialysis patients with anemia: A randomized clinical trial. PLoS One (2017) 0.75

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