Tumor heterogeneity and the biology of cancer invasion and metastasis.

PubWeight™: 3.54‹?› | Rank: Top 1%

🔗 View Article (PMID 354778)

Published in Cancer Res on September 01, 1978

Authors

I J Fidler

Articles citing this

(truncated to the top 100)

Intra-tumour heterogeneity: a looking glass for cancer? Nat Rev Cancer (2012) 6.82

AACR centennial series: the biology of cancer metastasis: historical perspective. Cancer Res (2010) 4.89

Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity. Cell Rep (2014) 3.24

History of myeloid-derived suppressor cells. Nat Rev Cancer (2013) 3.14

Circulating tumor cells as a window on metastasis biology in lung cancer. Am J Pathol (2011) 2.76

The selection and characterization of an invasive variant of the B16 melanoma. Am J Pathol (1979) 2.42

Establishment of cell clones with different metastatic potential from the metastatic hepatocellular carcinoma cell line MHCC97. World J Gastroenterol (2001) 2.32

Epithelial-Mesenchymal Plasticity: A Central Regulator of Cancer Progression. Trends Cell Biol (2015) 1.87

Metastatic colonization potential of primary tumour cells in mice. Br J Cancer (1979) 1.62

Interactions of tumor cells with vascular endothelial cell monolayers: a model for metastatic invasion. Proc Natl Acad Sci U S A (1979) 1.57

The origins and implications of intratumor heterogeneity. Cancer Prev Res (Phila) (2010) 1.55

Clonal evolution in hematological malignancies and therapeutic implications. Leukemia (2013) 1.50

Comparative mechanisms of cancer cell migration through 3D matrix and physiological microtracks. Am J Physiol Cell Physiol (2014) 1.50

Increasing metastatic potential is associated with increasing genetic instability of clones isolated from murine neoplasms. Proc Natl Acad Sci U S A (1981) 1.44

Cancer evolution: mathematical models and computational inference. Syst Biol (2014) 1.36

Molecular mapping of tumor heterogeneity on clinical tissue specimens with multiplexed quantum dots. ACS Nano (2010) 1.31

Intratumor heterogeneity in evolutionary models of tumor progression. Genetics (2011) 1.31

A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis. Nature (2015) 1.30

Metastasizing capacity of tumour cells from spontaneous metastases of transplanted murine tumours. Br J Cancer (1980) 1.29

Expression profiling of primary tumors and matched lymphatic and lung metastases in a xenogeneic breast cancer model. Am J Pathol (2005) 1.29

Expression of occludin, tight-junction-associated protein, in human digestive tract. Am J Pathol (1997) 1.28

Evolving role of molecular imaging with PET in detecting and characterizing heterogeneity of cancer tissue at the primary and metastatic sites, a plausible explanation for failed attempts to cure malignant disorders. Eur J Nucl Med Mol Imaging (2011) 1.27

No common denominator for breast cancer lymph node metastasis. Br J Cancer (2005) 1.20

Leading malignant cells initiate collective epithelial cell invasion in a three-dimensional heterotypic tumor spheroid model. Clin Exp Metastasis (2013) 1.18

Cancer metastasis networks and the prediction of progression patterns. Br J Cancer (2009) 1.17

Evolutionary dynamics of intratumor heterogeneity. PLoS One (2011) 1.14

Immunocytochemical localization of urokinase-type plasminogen activator in Lewis lung carcinoma. J Cell Biol (1984) 1.13

Platelets and cancer: a casual or causal relationship: revisited. Cancer Metastasis Rev (2014) 1.07

Kinetics and ultrastructural studies of the induction of rat alveolar macrophage fusion by mediators released from mitogen-stimulated lymphocytes. Am J Pathol (1981) 1.07

17 beta-estradiol regulates and v-Ha-ras transfection constitutively enhances MCF7 breast cancer cell interactions with basement membrane. Proc Natl Acad Sci U S A (1986) 1.07

Arachidonic acid stimulates cell adhesion through a novel p38 MAPK-RhoA signaling pathway that involves heat shock protein 27. J Biol Chem (2009) 1.06

Immunologic studies of membrane mutants of a highly metastatic murine tumor. Am J Pathol (1979) 1.05

The network of epithelial-mesenchymal transition: potential new targets for tumor resistance. J Cancer Res Clin Oncol (2014) 1.04

A highly invasive human glioblastoma pre-clinical model for testing therapeutics. J Transl Med (2008) 1.03

Characterization of human colon carcinoma cell lines isolated from a single primary tumour. Br J Cancer (1983) 1.02

Effects of inoculation site and Matrigel on growth and metastasis of human breast cancer cells. Br J Cancer (1994) 1.01

Microfabricated physical spatial gradients for investigating cell migration and invasion dynamics. PLoS One (2011) 1.00

Metastatic variants are generated spontaneously at a high rate in mouse KHT tumor. Proc Natl Acad Sci U S A (1982) 0.99

A general framework for analyzing tumor subclonality using SNP array and DNA sequencing data. Genome Biol (2014) 0.96

Utilizing the molecular gateway: the path to personalized cancer management. Clin Chem (2009) 0.95

Environmental control of invasiveness and metastatic dissemination of tumor cells: the role of tumor cell-host cell interactions. Cell Commun Signal (2010) 0.95

Pancreatic cancer stem cells: fact or fiction? Biochim Biophys Acta (2009) 0.93

Breast cancer redox heterogeneity detectable with chemical exchange saturation transfer (CEST) MRI. Mol Imaging Biol (2014) 0.93

Endosialin expression in side populations in human sarcoma cell lines. Oncol Lett (2011) 0.92

Neoplastic conversion of preneoplastic Syrian hamster cells: rate estimation by fluctuation analysis. Mol Cell Biol (1983) 0.92

Dendritic cell-based vaccination in cancer: therapeutic implications emerging from murine models. Front Immunol (2015) 0.91

Gradient generation platforms: new directions for an established microfluidic technology. Lab Chip (2014) 0.91

Ablation of a site of progression with stereotactic body radiation therapy extends sunitinib treatment from 14 to 22 months. J Clin Oncol (2013) 0.90

Do metastases arise from pre-existing subpopulations of cancer cells? Br J Cancer (1983) 0.89

Murine melanoma: a model for intracranial metastasis. Br J Cancer (1980) 0.89

Cancer immunoediting of the NK group 2D ligand H60a. J Immunol (2011) 0.89

Deformability of Tumor Cells versus Blood Cells. Sci Rep (2015) 0.88

Computer aided automatic detection of malignant lesions in diffuse optical mammography. Med Phys (2010) 0.88

Multi-layered cancer chromosomal instability phenotype. Front Oncol (2013) 0.88

Expression of proliferating cell nuclear antigen and CD44 variant exon 6 in primary tumors and corresponding lymph node metastases of colorectal carcinoma with Dukes' stage C or D. World J Gastroenterol (2003) 0.88

Human melanoma metastases demonstrate nonstochastic site-specific antigen heterogeneity that correlates with T-cell infiltration. Clin Cancer Res (2014) 0.87

Early endostatin treatment inhibits metastatic seeding of murine colorectal cancer cells in the liver and their adhesion to endothelial cells. Br J Cancer (2005) 0.87

Circulating Tumor Cells: Who is the Killer? Cancer Microenviron (2014) 0.87

Activation of protein kinase C-alpha isoform in murine melanoma cells with high metastatic potential. Clin Exp Metastasis (1997) 0.87

Clusters of circulating tumor cells traverse capillary-sized vessels. Proc Natl Acad Sci U S A (2016) 0.86

Do we need to redefine a cancer metastasis and staging definitions? Breast Dis (2007) 0.86

Effects of tumor microenvironment heterogeneity on nanoparticle disposition and efficacy in breast cancer tumor models. Clin Cancer Res (2014) 0.86

Surface protein distributions in cells isolated from solid tumours and their metastases. Br J Cancer (1979) 0.85

Quantitative in vivo cell-surface receptor imaging in oncology: kinetic modeling and paired-agent principles from nuclear medicine and optical imaging. Phys Med Biol (2015) 0.85

Melanoma-initiating cells: a compass needed. EMBO Rep (2009) 0.85

Do cancer cells undergo phenotypic switching? The case for imperfect cancer stem cell markers. Sci Rep (2012) 0.85

Isolation of a human gallbladder cancer cell clone with high invasive phenotype in vitro and metastatic potential in orthotopic model and inhibition of its invasiveness by heparanase antisense oligodeoxynucleotides. Clin Exp Metastasis (2007) 0.84

Properties of metastatic and nonmetastatic cloned subpopulations of an ultraviolet-light-induced murine fibrosarcoma of recent origin. Am J Pathol (1979) 0.84

Comparison of vascularity and angiogenesis in primary invasive mammary carcinomas and in their respective axillary lymph node metastases. Clin Exp Metastasis (2000) 0.84

Measurement of protein kinase B activity in single primary human pancreatic cancer cells. Anal Chem (2014) 0.84

Understanding tissue context influences on intratumour heterogeneity. Nat Cell Biol (2014) 0.84

SDA, a DNA aptamer inhibiting E- and P-selectin mediated adhesion of cancer and leukemia cells, the first and pivotal step in transendothelial migration during metastasis formation. PLoS One (2014) 0.83

miR-125b induces cellular senescence in malignant melanoma. BMC Dermatol (2014) 0.82

The challenge of targeting metastasis. Cancer Metastasis Rev (2015) 0.82

Potential roles for prions and protein-only inheritance in cancer. Cancer Metastasis Rev (2012) 0.82

Intratumoral heterogeneity: Clonal cooperation in epithelial-to-mesenchymal transition and metastasis. Cell Adh Migr (2014) 0.82

Investigating intratumour heterogeneity by single-cell sequencing. Asian J Androl (2013) 0.81

A new computational tool for the phenomenological analysis of multipassage tumor growth curves. PLoS One (2009) 0.80

In vivo major histocompatibility complex class I (MHCI) expression on MHCIlow tumor cells is regulated by gammadelta T and NK cells during the early steps of tumor growth. Cancer Immun (2009) 0.80

Next-Generation Sequencing Approaches in Cancer: Where Have They Brought Us and Where Will They Take Us? Cancers (Basel) (2015) 0.80

Cathepsin B and other proteases in human colorectal carcinoma. Am J Pathol (1994) 0.80

Migration-prone glioma cells show curcumin resistance associated with enhanced expression of miR-21 and invasion/anti-apoptosis-related proteins. Oncotarget (2015) 0.79

Antigenic heterogeneity and individuality in adenocarcinomas of the rectum and their secondaries. Br J Cancer (1987) 0.79

Effect of enzymic removal of cell surface constituents on metastatic colonisation potential of mouse mammary tumour cells. Br J Cancer (1983) 0.79

Algorithmic methods to infer the evolutionary trajectories in cancer progression. Proc Natl Acad Sci U S A (2016) 0.79

Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma. Oncotarget (2016) 0.78

Some aspects of the metastatic process. J Clin Pathol (1982) 0.78

Surface properties of cells isolated from non-metastasizing and metastasizing hamster lymphosarcomas. Br J Cancer (1980) 0.77

Melphalan sensitivity as a function of progressive metastatic growth in two subpopulations of a mouse mammary tumour. Br J Cancer (1993) 0.77

Microenvironmental influences on the in vivo behavior of neoplastic lymphocytes. Proc Natl Acad Sci U S A (1979) 0.77

Pathology to enhance precision medicine in oncology: lessons from landscape ecology. Adv Anat Pathol (2015) 0.77

Low-order non-spatial effects dominate second-order spatial effects in the texture quantifier analysis of 18F-FDG-PET images. PLoS One (2015) 0.77

Xenotransplantation elicits salient tumorigenicity of adult T-cell leukemia-derived cells via aberrant AKT activation. Cancer Sci (2016) 0.77

Tumor Evolution: Linear, Branching, Neutral or Punctuated? Biochim Biophys Acta (2017) 0.77

Culture of low passage colorectal cancer cells and demonstration of variation in selected tumour marker expression. Cytotechnology (2013) 0.76

A High Throughput Micro-Chamber Array Device for Single Cell Clonal Cultivation and Tumor Heterogeneity Analysis. Sci Rep (2015) 0.76

Characterisation of Walker 256 breast carcinoma cells from two tumour cell banks as assessed using two models of secondary brain tumours. Cancer Cell Int (2013) 0.75

Cancer: crab or chimera? The clinical implications of cancer cell heterogeneity. Trans Am Clin Climatol Assoc (1981) 0.75

The Walker 256 Breast Cancer Cell- Induced Bone Pain Model in Rats. Front Pharmacol (2016) 0.75

Capillary collagen as the physical transport barrier in drug delivery to tumor microenvironment. Tissue Barriers (2015) 0.75

Articles by these authors

(truncated to the top 100)

Metastasis results from preexisting variant cells within a malignant tumor. Science (1977) 6.47

The pathogenesis of cancer metastasis. Nature (1980) 5.74

Selection of successive tumour lines for metastasis. Nat New Biol (1973) 5.03

Metastasis: quantitative analysis of distribution and fate of tumor emboli labeled with 125 I-5-iodo-2'-deoxyuridine. J Natl Cancer Inst (1970) 4.88

Biological diversity in metastatic neoplasms: origins and implications. Science (1982) 3.95

Biological behavior of malignant melanoma cells correlated to their survival in vivo. Cancer Res (1975) 3.59

Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma. Proc Natl Acad Sci U S A (1980) 3.38

The biology of cancer invasion and metastasis. Adv Cancer Res (1978) 2.94

Orthotopic models are necessary to predict therapy of transplantable tumors in mice. Cancer Metastasis Rev (1999) 2.83

Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis. Oncogene (2001) 2.71

In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice. Neoplasia (1999) 2.71

Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice. Cancer Res (1988) 2.67

Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice. Clin Cancer Res (1996) 2.59

The relationship of embolic homogeneity, number, size and viability to the incidence of experimental metastasis. Eur J Cancer (1973) 2.54

Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma. Cancer Res (2000) 2.43

Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis. Cancer Metastasis Rev (1986) 2.42

In vitro selection of murine B16 melanoma variants with enhanced tissue-invasive properties. Cancer Res (1980) 2.40

Interferon-alpha-mediated down-regulation of angiogenesis-related genes and therapy of bladder cancer are dependent on optimization of biological dose and schedule. Clin Cancer Res (1999) 2.39

Elevated expression of phosphatidylserine in the outer membrane leaflet of human tumor cells and recognition by activated human blood monocytes. Cancer Res (1991) 2.37

In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinomas implanted into nude mice. Cancer Res (1988) 2.36

Expression of angiogenesis-related genes and progression of human ovarian carcinomas in nude mice. J Natl Cancer Inst (1998) 2.36

Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice. Cancer Res (1986) 2.30

Expression of interleukin 8 correlates with the metastatic potential of human melanoma cells in nude mice. Cancer Res (1994) 2.28

Metastatic heterogeneity of cells from an ultraviolet light-induced murine fibrosarcoma of recent origin. Cancer Res (1978) 2.28

Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma. Cell (1997) 2.16

Metastatic behavior of human tumor cell lines grown in the nude mouse. Cancer Res (1984) 2.13

Organ selectivity for implantation survival and growth of B16 melanoma variant tumor lines. J Natl Cancer Inst (1976) 2.09

A human melanoma line heterogeneous with respect to metastatic capacity in athymic nude mice. J Natl Cancer Inst (1984) 2.08

Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells. J Natl Cancer Inst (1990) 2.00

Metastatic model for human prostate cancer using orthotopic implantation in nude mice. J Natl Cancer Inst (1992) 2.00

Specificity of arrest, survival, and growth of selected metastatic variant cell lines. Cancer Res (1978) 1.99

Blockade of nuclear factor-kappaB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8. Cancer Res (2000) 1.98

Role of organ selectivity in the determination of metastatic patterns of B16 melanoma. Cancer Res (1980) 1.97

Relative malignant potential of human breast carcinoma cell lines established from pleural effusions and a brain metastasis. Invasion Metastasis (1991) 1.95

Mekk3 is essential for early embryonic cardiovascular development. Nat Genet (2000) 1.95

A simple quantitative assay for studying the invasive potential of high and low human metastatic variants. Cancer Lett (1987) 1.94

Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas. Proc Natl Acad Sci U S A (1995) 1.87

Interactions among clonal subpopulations affect stability of the metastatic phenotype in polyclonal populations of B16 melanoma cells. Proc Natl Acad Sci U S A (1981) 1.87

Isolation and characterization of metastatic variants from human transitional cell carcinoma passaged by orthotopic implantation in athymic nude mice. J Urol (1995) 1.82

Expression of interleukin-8 correlates with vascularity in human gastric carcinomas. Am J Pathol (1998) 1.75

Angiogenesis and metastasis. Eur J Cancer (1996) 1.72

Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells. Clin Cancer Res (1995) 1.71

Inhibition of murine melanoma experimental metastasis by recombinant desulfatohirudin, a highly specific thrombin inhibitor. Cancer Res (1991) 1.70

The effect of human recombinant macrophage colony-stimulating factor (CSF-1) on the murine mononuclear phagocyte system in vivo. J Immunol (1988) 1.63

In vivo selection of human renal cell carcinoma cells with high metastatic potential in nude mice. Clin Exp Metastasis (1989) 1.62

Destruction of bystander cells by tumor cells transfected with inducible nitric oxide (NO) synthase gene. J Natl Cancer Inst (1997) 1.55

Angiogenesis and breast cancer metastasis. Lancet (1995) 1.55

Expression of interleukin-8 correlates with angiogenesis, tumorigenicity, and metastasis of human prostate cancer cells implanted orthotopically in nude mice. Neoplasia (2001) 1.52

Evidence for the clonal origin of spontaneous metastases. Science (1982) 1.52

Orthotopic and ectopic organ environments differentially influence the sensitivity of murine colon carcinoma cells to doxorubicin and 5-fluorouracil. Int J Cancer (1992) 1.50

Role of natural killer cells in the destruction of circulating tumor emboli. J Natl Cancer Inst (1980) 1.49

Nuclear factor-kappaB activity correlates with growth, angiogenesis, and metastasis of human melanoma cells in nude mice. Clin Cancer Res (2000) 1.48

Acidic pH-induced elevation in interleukin 8 expression by human ovarian carcinoma cells. Cancer Res (2000) 1.47

Metastatic behavior of tumor cells isolated from primary and metastatic human colorectal carcinomas implanted into different sites in nude mice. Cancer Res (1986) 1.47

Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic. Clin Cancer Res (1999) 1.45

Increasing metastatic potential is associated with increasing genetic instability of clones isolated from murine neoplasms. Proc Natl Acad Sci U S A (1981) 1.44

Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine macrophages by natural and synthetic bacterial products. J Exp Med (1993) 1.44

Characterization in vivo and in vitro of tumor cells selected for resistance to syngeneic lymphocyte-mediated cytotoxicity. Cancer Res (1976) 1.44

Macrophages and metastasis--a biological approach to cancer therapy. Cancer Res (1985) 1.43

Specific chromosomal defects associated with metastatic potential in K-1735 melanoma clones. Involvement of chromosomes 4 and 14. Cancer Genet Cytogenet (1991) 1.41

Involvement of macrophages in the eradication of established metastases following intravenous injection of liposomes containing macrophage activators. Cancer Res (1982) 1.40

Experimental nude mouse model of human colorectal cancer liver metastases. J Natl Cancer Inst (1986) 1.38

Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon cancer cells. J Natl Cancer Inst (1994) 1.37

Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells. J Exp Med (1995) 1.37

Demonstration of multiple phenotypic diversity in a murine melanoma of recent origin. J Natl Cancer Inst (1981) 1.37

Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis. Cancer Res (2000) 1.36

Eradication of spontaneous metastases and activation of alveolar macrophages by intravenous injection of liposomes containing muramyl dipeptide. Proc Natl Acad Sci U S A (1981) 1.34

Evidence that intravenously derived murine pulmonary melanoma metastases can originate from the expansion of a single tumor cell. Cancer Res (1986) 1.33

Relationship of host immune status to tumor cell arrest, distribution, and survival in experimental metastasis. Cancer (1977) 1.33

Interleukin 8: an autocrine growth factor for human ovarian cancer. Oncol Res (2000) 1.33

Correlation of growth capacity of human tumor cells in hard agarose with their in vivo proliferative capacity at specific metastatic sites. J Natl Cancer Inst (1989) 1.32

Analysis of the fate of systemically administered liposomes and implications for their use in drug delivery. Cancer Res (1982) 1.32

Differential permeability of the blood-brain barrier in experimental brain metastases produced by human neoplasms implanted into nude mice. Am J Pathol (1992) 1.31

Inhibition of pulmonary metastasis by intravenous injection of specifically activated macrophages. Cancer Res (1974) 1.30

Angiogenic molecules and cancer metastasis. In Vivo (1998) 1.30

Inhibition of malignant ascites and growth of human ovarian carcinoma by oral administration of a potent inhibitor of the vascular endothelial growth factor receptor tyrosine kinases. Int J Oncol (2000) 1.28

Angiogenic heterogeneity: regulation of neoplastic angiogenesis by the organ microenvironment. J Natl Cancer Inst (2001) 1.28

Therapy of spontaneous metastases by intravenous injection of liposomes containing lymphokines. Science (1980) 1.28

Natural and recombinant human interleukin 1-beta is cytotoxic for human melanoma cells. J Immunol (1986) 1.27

Modulation of the invasive phenotype of human colon carcinoma cells by organ specific fibroblasts of nude mice. Differentiation (1992) 1.26

Transfection of interleukin-8 increases angiogenesis and tumorigenesis of human gastric carcinoma cells in nude mice. Br J Cancer (1999) 1.26

Production of experimental malignant pleural effusions is dependent on invasion of the pleura and expression of vascular endothelial growth factor/vascular permeability factor by human lung cancer cells. Am J Pathol (2000) 1.26

Characterization of human colon carcinoma variant cells selected for sialyl Lex carbohydrate antigen: liver colonization and adhesion to vascular endothelial cells. Exp Cell Res (1995) 1.25

Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assessment of outer-leaflet lipid by prothrombinase complex formation. Proc Natl Acad Sci U S A (1989) 1.24

Clonal expansion of cells with trisomy of chromosomes 12 and X in an EBV-transformed lymphoblastoid cell line and establishment of a tumorigenic monoclonal cell line (48,XX,+X,+12). Cytogenet Cell Genet (1993) 1.24

Inhibition of basic fibroblast growth factor expression, angiogenesis, and growth of human bladder carcinoma in mice by systemic interferon-alpha administration. Cancer Res (1998) 1.24

Direct correlation between MUC18 expression and metastatic potential of human melanoma cells. Melanoma Res (1993) 1.23

Design of liposomes to improve delivery of macrophage-augmenting agents to alveolar macrophages. Cancer Res (1980) 1.23

Genetic control of cancer metastasis. J Natl Cancer Inst (1990) 1.23

Correlation of metastasis-related gene expression with metastatic potential in human prostate carcinoma cells implanted in nude mice using an in situ messenger RNA hybridization technique. Am J Pathol (1997) 1.23

Hypoxia-induced elevation in interleukin-8 expression by human ovarian carcinoma cells. Cancer Res (1999) 1.23

A rapid colorimetric in situ messenger RNA hybridization technique for analysis of epidermal growth factor receptor in paraffin-embedded surgical specimens of human colon carcinomas. Cancer Res (1993) 1.22

Role of nitric oxide in lysis of tumor cells by cytokine-activated endothelial cells. Cancer Res (1991) 1.22

Progressive growth of infantile cutaneous hemangiomas is directly correlated with hyperplasia and angiogenesis of adjacent epidermis and inversely correlated with expression of the endogenous angiogenesis inhibitor, IFN-beta. Int J Oncol (1999) 1.21

Regulation of interleukin-8 expression in human melanoma cells by the organ environment. Cancer Res (1995) 1.21

Different growth pattern and biologic behavior of human renal cell carcinoma implanted into different organs of nude mice. J Natl Cancer Inst (1987) 1.21

Inhibition of growth and metastasis of human pancreatic cancer growing in nude mice by PTK 787/ZK222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases. Cancer Biother Radiopharm (2001) 1.21

Activation in vitro of mouse macrophages by syngeneic, allogeneic, or xenogeneic lymphocyte supernatants. J Natl Cancer Inst (1975) 1.20

Inverse correlation between expression of inducible nitric oxide synthase activity and production of metastasis in K-1735 murine melanoma cells. Cancer Res (1994) 1.19

Increased adherence of sickled and phosphatidylserine-enriched human erythrocytes to cultured human peripheral blood monocytes. J Clin Invest (1985) 1.18