Published in Bull Math Biol on January 01, 1986
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res (1997) 665.31
Protein sequence similarity searches using patterns as seeds. Nucleic Acids Res (1998) 23.87
Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements. Nucleic Acids Res (2001) 22.33
A tool for multiple sequence alignment. Proc Natl Acad Sci U S A (1989) 17.09
Protein database searches using compositionally adjusted substitution matrices. FEBS J (2005) 8.14
SAGA: sequence alignment by genetic algorithm. Nucleic Acids Res (1996) 7.89
The estimation of statistical parameters for local alignment score distributions. Nucleic Acids Res (2001) 3.61
Detecting conserved regulatory elements with the model genome of the Japanese puffer fish, Fugu rubripes. Proc Natl Acad Sci U S A (1995) 2.65
Nucleotide sequence of the streptococcal pyrogenic exotoxin type B gene and relationship between the toxin and the streptococcal proteinase precursor. J Bacteriol (1990) 2.50
Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins. Genetics (1992) 2.50
MACSE: Multiple Alignment of Coding SEquences accounting for frameshifts and stop codons. PLoS One (2011) 2.06
Identification of a divergent M protein gene and an M protein-related gene family in Streptococcus pyogenes serotype 49. J Bacteriol (1989) 2.04
Fc-receptor and M-protein genes of group A streptococci are products of gene duplication. Proc Natl Acad Sci U S A (1989) 1.97
Homology modeling using parametric alignment ensemble generation with consensus and energy-based model selection. Nucleic Acids Res (2006) 1.96
Nucleotide sequences of the genes regulating O-polysaccharide antigen chain length (rol) from Escherichia coli and Salmonella typhimurium: protein homology and functional complementation. J Bacteriol (1992) 1.80
Nucleotide sequence of streptococcal pyrogenic exotoxin type C. Infect Immun (1988) 1.56
The construction and use of log-odds substitution scores for multiple sequence alignment. PLoS Comput Biol (2010) 1.54
Comparison of the leader sequences of four group A streptococcal M protein genes. Nucleic Acids Res (1988) 1.44
Evaluation of two commercial global miRNA expression profiling platforms for detection of less abundant miRNAs. BMC Genomics (2011) 1.39
Molecular cloning of a candidate chicken prion protein. Proc Natl Acad Sci U S A (1992) 1.38
Two versions of the gene encoding the 41-kilodalton subunit of the telomere binding protein of Oxytricha nova. Proc Natl Acad Sci U S A (1990) 1.25
Mouse mast cell gp49B1 contains two immunoreceptor tyrosine-based inhibition motifs and suppresses mast cell activation when coligated with the high-affinity Fc receptor for IgE. Proc Natl Acad Sci U S A (1996) 1.18
Coevolution of persistently infecting small DNA viruses and their hosts linked to host-interactive regulatory domains. Proc Natl Acad Sci U S A (1993) 1.16
Molecular cloning of telomere-binding protein genes from Stylonychia mytilis. Nucleic Acids Res (1991) 1.08
Identification of a conserved sequence in the non-coding regions of many human genes. Nucleic Acids Res (1989) 1.05
Proline biosynthesis in Saccharomyces cerevisiae: molecular analysis of the PRO1 gene, which encodes gamma-glutamyl kinase. J Bacteriol (1992) 0.90
Ribosomal protein L25 from Trypanosoma brucei: phylogeny and molecular co-evolution of an rRNA-binding protein and its rRNA binding site. Nucleic Acids Res (1993) 0.88
MetaPathways v2.5: quantitative functional, taxonomic and usability improvements. Bioinformatics (2015) 0.81
Modular and configurable optimal sequence alignment software: Cola. Source Code Biol Med (2014) 0.80
A universal genomic coordinate translator for comparative genomics. BMC Bioinformatics (2014) 0.77
The comparative analysis of statistics, based on the likelihood ratio criterion, in the automated annotation problem. BMC Bioinformatics (2008) 0.76
Determination of a Screening Metric for High Diversity DNA Libraries. PLoS One (2016) 0.75
Aligning coding sequences with frameshift extension penalties. Algorithms Mol Biol (2017) 0.75
Robust sequence alignment using evolutionary rates coupled with an amino acid substitution matrix. BMC Bioinformatics (2015) 0.75
A systematic comparison of error correction enzymes by next-generation sequencing. Nucleic Acids Res (2017) 0.75
Detecting subtle sequence signals: a Gibbs sampling strategy for multiple alignment. Science (1993) 36.84
Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes. Proc Natl Acad Sci U S A (1990) 24.42
Protein sequence similarity searches using patterns as seeds. Nucleic Acids Res (1998) 23.87
Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements. Nucleic Acids Res (2001) 22.33
Detection of conserved segments in proteins: iterative scanning of sequence databases with alignment blocks. Proc Natl Acad Sci U S A (1994) 18.46
A tool for multiple sequence alignment. Proc Natl Acad Sci U S A (1989) 17.09
A workbench for multiple alignment construction and analysis. Proteins (1991) 16.96
A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins. FASEB J (1997) 15.10
Applications and statistics for multiple high-scoring segments in molecular sequences. Proc Natl Acad Sci U S A (1993) 12.10
BRCA1 protein products ... Functional motifs... Nat Genet (1996) 11.50
SAGEmap: a public gene expression resource. Genome Res (2000) 10.41
Locally optimal subalignments using nonlinear similarity functions. Bull Math Biol (1986) 9.10
A public database for gene expression in human cancers. Cancer Res (1999) 8.81
IMPALA: matching a protein sequence against a collection of PSI-BLAST-constructed position-specific score matrices. Bioinformatics (1999) 6.91
Significance of nucleotide sequence alignments: a method for random sequence permutation that preserves dinucleotide and codon usage. Mol Biol Evol (1985) 3.11
Statistical methods and insights for protein and DNA sequences. Annu Rev Biophys Biophys Chem (1991) 2.32
C3bi receptor (complement receptor type 3) recognizes a region of complement protein C3 containing the sequence Arg-Gly-Asp. Proc Natl Acad Sci U S A (1987) 2.31
Characterization of gene expression in resting and activated mast cells. J Exp Med (1998) 2.24
Equal animals. Nature (1990) 2.09
Looking at proteins: representations, folding, packing, and design. Biophysical Society National Lecture, 1992. Biophys J (1992) 2.08
Immunochemical localization and amino acid sequences of crossreactive epitopes within the group A streptococcal M6 protein. J Exp Med (1986) 2.03
Mapping of the alpha-actinin binding site within the beta 1 integrin cytoplasmic domain. J Biol Chem (1993) 1.95
Complete nucleotide sequence of the neuraminidase gene of influenza B virus. Proc Natl Acad Sci U S A (1982) 1.85
Tert-butoxycarbonylaminoacyl-4-(oxymethyl)-phenylacetamidomethyl-resin, a more acid-resistant support for solid-phase peptide synthesis. J Am Chem Soc (1976) 1.68
Immunoglobulin VH gene structure and diversity in Heterodontus, a phylogenetically primitive shark. Proc Natl Acad Sci U S A (1985) 1.54
Eukaryotic translation elongation factor 1 gamma contains a glutathione transferase domain--study of a diverse, ancient protein superfamily using motif search and structural modeling. Protein Sci (1994) 1.39
Statistics of sequence-structure threading. Curr Opin Struct Biol (1995) 1.38
Complete nucleotide sequences of three VH genes in Caiman, a phylogenetically ancient reptile: evolutionary diversification in coding segments and variation in the structure and organization of recombination elements. Proc Natl Acad Sci U S A (1985) 1.34
Designed coiled-coil proteins: synthesis and spectroscopy of two 78-residue alpha-helical dimers. Biochemistry (1991) 1.33
Engineering of betabellin 14D: disulfide-induced folding of a beta-sheet protein. Protein Sci (1994) 1.31
Anaphylatoxin-induced histamine release with human leukocytes: studies of C3a leukocyte binding and histamine release. J Clin Invest (1979) 1.20
Synthetic peptides with the biological activities and specificity of human C3a anaphylatoxin. Proc Natl Acad Sci U S A (1977) 1.16
Structural basis of the oligomerization of hepatitis delta antigen. Structure (1998) 1.14
The active site of C3a anaphylatoxin. J Biol Chem (1980) 1.07
Self-association of a synthetic peptide from the N terminus of the hepatitis delta virus protein into an immunoreactive alpha-helical multimer. Proc Natl Acad Sci U S A (1995) 1.05
Conformational analysis of COOH-terminal segments of human C3a. Evidence of ordered conformation in an active 21-residue peptide. J Biol Chem (1984) 1.05
A nonlinear measure of subalignment similarity and its significance levels. Bull Math Biol (1986) 1.03
Use of chlorinated benzyloxycarbonyl protecting groups to eliminate N -branching at lysine during solid-phase peptide synthesis. J Am Chem Soc (1973) 1.02
Complete nucleotide sequence of an immunoglobulin VH gene homologue from Caiman, a phylogenetically ancient reptile. Nature (1983) 1.01
Purification and properties of mammalian toxins from the venom of Brazilian Scorpion Tityus serrulatus Lutz and Mello. Arch Biochem Biophys (1977) 1.00
Acid stability of several benzylic protecting groups used in solid-phase peptide synthesis. Rearrangement of O-benzyltyrosine to 3-benzyltyrosine. J Am Chem Soc (1973) 1.00
Engineering of betabellin-15D: a 64 residue beta sheet protein that forms long narrow multimeric fibrils. Protein Sci (1998) 0.99
An equilibrium model of the metastable binding sites of alpha 2-macroglobulin and complement proteins C3 and C4. J Biol Chem (1982) 0.97
Free energies for refolding of the common beta turn into the inverse-common beta turn: simulation of the role of D/L chirality. Proc Natl Acad Sci U S A (1993) 0.95
Synthesis of redox derivatives of lysine and related peptides containing phenothiazine or tris(2,2'-bipyridine)ruthenium(II). Int J Pept Protein Res (1991) 0.95
Towards a molecular and atomic anatomy of calmodulin and calmodulin-binding proteins. Adv Cyclic Nucleotide Protein Phosphorylation Res (1984) 0.94
Betabellins 15D and 16D, de Novo designed beta-sandwich proteins that have amyloidogenic properties. J Struct Biol (2000) 0.93
Inhibition of C1-mediated immune hemolysis by monomeric and dimeric peptides from the second constant domain of human immunoglobulin G. J Immunol (1981) 0.90
Deuterium exchange of alpha-helices and beta-sheets as monitored by electrospray ionization mass spectrometry. Protein Sci (1994) 0.90
Affinity purification of synthetic peptides. Proc Natl Acad Sci U S A (1976) 0.87
Scorpion toxins from Centruroides noxius and Tityus serrulatus. Primary structures and sequence comparison by metric analysis. Biochem J (1985) 0.87
Engineering of site-directed antisera against vertebrate calmodulin by using synthetic peptide immunogens containing an immunoreactive site. Proc Natl Acad Sci U S A (1983) 0.87
Solid-phase peptide synthesis under continuous-flow conditions. Proc Natl Acad Sci U S A (1981) 0.86
Synthetic lactam and thiolactone models of protein metastable binding sites. Ann N Y Acad Sci (1983) 0.85
Human C5a-related synthetic peptides as neutrophil chemotactic factors. Biochem Biophys Res Commun (1979) 0.85
The occurrence of chitin in the spore wall of Glugea weissenbergi. J Invertebr Pathol (1969) 0.84
Schedule optimization of hydroxyurea and 1-beta-D-arabinofuranosylcytosine in sarcoma 180 in vitro. Cancer Res (1982) 0.83
A radioimmunoassay for thymosin alpha-1. J Immunol Methods (1986) 0.83
Active site of C3a anaphylatoxin: contributions of the lipophilic and orienting residues. Biochemistry (1984) 0.82
Internal duplication in human alpha 1 and beta 1 interferons. Proc Natl Acad Sci U S A (1984) 0.82
Antibody response in Heterodontus. Mol Cell Biochem (1982) 0.82
Elucidation of a minimal immunoreactive site of vertebrate calmodulin. Arch Biochem Biophys (1983) 0.82
Suppression of humoral immune responses by synthetic C3a peptides. J Immunol (1983) 0.81
Peptide models of protein metastable binding sites: competitive kinetics of isomerization and hydrolysis. Biochemistry (1986) 0.81
Inhibition of the classical complement pathway by synthetic peptides from the second constant domain of the heavy chain of human immunoglobulin G. Biochemistry (1981) 0.81
Photochemical energy conversion in a helical oligoproline assembly. Proc Natl Acad Sci U S A (1996) 0.80
Rational design of a three-heptad coiled-coil protein and comparison by molecular dynamics simulation with the GCN4 coiled coil: presence of interior three-center hydrogen bonds. Protein Sci (1994) 0.80
Significance levels for biological sequence comparison using non-linear similarity functions. Bull Math Biol (1988) 0.80
Radioimmunoassays for the thymic hormone serum thymic factor (FTS). J Immunol Methods (1983) 0.79
Molecular basis for the temperature-dependent insolubility of cryoglobulins. X. The amino acid sequence of the heavy chain variable region of McE. J Immunol (1981) 0.79
The T-lymphocyte as a diploid reference standard for flow cytometry. Cancer Res (1979) 0.79
Differentiation between selected pairs of tripeptide diastereomers by tandem mass spectrometry on a hybrid tandem mass spectrometer. Rapid Commun Mass Spectrom (1993) 0.79
Larval release in brachyuran crustaceans Functional similarity of peptide pheromone receptor and catalytic site of trypsin. J Chem Ecol (1990) 0.78
Sequence alignment of calmodulin domains by metric analysis. Ann N Y Acad Sci (1980) 0.78
Synthetic peptides from mouse Fc receptor (MoFc gamma RII) that alter the binding of IgG to MoFc gamma RII. Biochemistry (1997) 0.78
Designed polyanionic coiled-coil proteins: acceleration of heparin cofactor II inhibition of thrombin. Int J Pept Protein Res (1995) 0.78
Molecular basis for the temperature-dependent insolubility of cryoglobulins--XI. Sequence comparison of the heavy-chain variable regions of the human cryoimmunoglobulins McE and Hil by metric analysis. Mol Immunol (1982) 0.78
Electron microscope study of the everted polar filament of Glugea weissenbergi (Microsporida, Nosematidae). J Protozool (1968) 0.76
Metal-ion binding and limited proteolysis of betabellin 15D, a designed beta-sandwich protein. J Am Soc Mass Spectrom (1999) 0.75
Inhibition of thrombin by synthetic hirudin peptides. FEBS Lett (1990) 0.75
Contraction of guinea pig lung by synthetic oligopeptides related to human C3a. Immunopharmacology (1984) 0.75
Antigenic specificity of a rabbit antiserum raised against the 15-28 segment of thymosin alpha 1. Mol Immunol (1986) 0.75
The linked phi psi chain plot for visual comparison of the backbone conformation of peptides and proteins. Int J Pept Protein Res (1995) 0.75
The active site of human C4a anaphylatoxin. Mol Immunol (1983) 0.75
Engineering of five 88-residue receptor-adhesive modular proteins containing a parallel alpha-helical coiled coil and two RGD ligand sites. Int J Pept Protein Res (1995) 0.75
Antigenic specificity of two antibodies directed against the thymic hormone serum thymic factor (FTS). Mol Immunol (1982) 0.75
Phylogenetic diversification of immunoglobulin VH genes. Dev Comp Immunol (1984) 0.75
Biophysical characterization of betabellin 16D: a beta-sandwich protein that forms narrow fibrils which associate into broad ribbons. Biochem Biophys Res Commun (1999) 0.75
Superpotent synthetic tripeptide mimics of the mud-crab pumping pheromone. Int J Pept Protein Res (1993) 0.75
Synthesis of 2-methyl and 2-carboxymethyl derivatives of ornithine and arginine. Int J Pept Protein Res (1983) 0.75