Published in J Clin Pharmacol on September 01, 1987
Presenting clinical pharmacology and therapeutics: general introduction. Br J Clin Pharmacol (1993) 1.02
A controlled trial of teaching critical appraisal of the clinical literature to medical students. JAMA (1987) 14.20
Thrombolysis in Myocardial Infarction (TIMI) Trial, Phase I: A comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge. Circulation (1987) 5.73
Circadian variation in the frequency of onset of acute myocardial infarction. N Engl J Med (1985) 5.09
Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy. Nucleic Acids Res (1996) 4.75
Identification of a genetic locus for familial atrial fibrillation. N Engl J Med (1997) 4.66
Second dose of measles, mumps, and rubella vaccine: questionnaire survey of health professionals. BMJ (2001) 4.50
Determining optimal therapy--randomized trials in individual patients. N Engl J Med (1986) 4.49
Identification of a gene responsible for familial Wolff-Parkinson-White syndrome. N Engl J Med (2001) 4.46
Mutations in the gene for cardiac myosin-binding protein C and late-onset familial hypertrophic cardiomyopathy. N Engl J Med (1998) 4.29
Synthesis of the yeast cell wall and its regulation. Annu Rev Biochem (1982) 4.26
Do sick newborn infants benefit from participation in a randomized clinical trial? J Pediatr (1999) 3.98
Comparison of percutaneous and surgical tracheostomies. Chest (1996) 3.56
WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseases. Cell Mol Life Sci (2001) 3.38
A clinician's guide for conducting randomized trials in individual patients. CMAJ (1988) 3.35
Tissue Doppler imaging consistently detects myocardial abnormalities in patients with hypertrophic cardiomyopathy and provides a novel means for an early diagnosis before and independently of hypertrophy. Circulation (2001) 3.33
Verifying quality and safety in health informatics services. BMJ (2001) 3.31
Angiotensin II blockade reverses myocardial fibrosis in a transgenic mouse model of human hypertrophic cardiomyopathy. Circulation (2001) 3.21
Mutations in the lactose operon caused by bacteriophage Mu. J Mol Biol (1972) 3.17
The impact of blinding on the results of a randomized, placebo-controlled multiple sclerosis clinical trial. Neurology (1994) 2.95
Ipsilateral breast tumor recurrence postlumpectomy is predictive of subsequent mortality: results from a randomized trial. Investigators of the Ontario Clinical Oncology Group. Int J Radiat Oncol Biol Phys (1994) 2.86
Allergen-induced increase in bronchial responsiveness to histamine: relationship to the late asthmatic response and change in airway caliber. J Allergy Clin Immunol (1982) 2.84
The molecular genetic basis for hypertrophic cardiomyopathy. J Mol Cell Cardiol (2001) 2.83
A comparison between heparin and low-dose aspirin as adjunctive therapy with tissue plasminogen activator for acute myocardial infarction. Heparin-Aspirin Reperfusion Trial (HART) Investigators. N Engl J Med (1990) 2.73
A standard heparin nomogram for the management of heparin therapy. Arch Intern Med (1991) 2.69
It's time for a change to a troponin standard. Circulation (2000) 2.69
The impact of socioeconomic status on health functioning as assessed by the SF-36 questionnaire: the Whitehall II Study. Am J Public Health (1997) 2.65
Reliability of a Standardized Mini-Mental State Examination compared with the traditional Mini-Mental State Examination. Am J Psychiatry (1991) 2.61
Desmin mutation responsible for idiopathic dilated cardiomyopathy. Circulation (1999) 2.59
Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins. Nature (1990) 2.46
Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death. Lancet (1993) 2.38
Echocardiography-guided ethanol septal reduction for hypertrophic obstructive cardiomyopathy. Circulation (1998) 2.37
APOE modifies the association between Aβ load and cognition in cognitively normal older adults. Neurology (2011) 2.35
Influence of coronary collateral vessels on myocardial infarct size in humans. Results of phase I thrombolysis in myocardial infarction (TIMI) trial. The TIMI Investigators. Circulation (1991) 2.33
Novel PRKAG2 mutation responsible for the genetic syndrome of ventricular preexcitation and conduction system disease with childhood onset and absence of cardiac hypertrophy. Circulation (2001) 2.25
Simvastatin induces regression of cardiac hypertrophy and fibrosis and improves cardiac function in a transgenic rabbit model of human hypertrophic cardiomyopathy. Circulation (2001) 2.23
Novel proteins with binding specificity for DNA CTG repeats and RNA CUG repeats: implications for myotonic dystrophy. Hum Mol Genet (1996) 2.23
A transgenic rabbit model for human hypertrophic cardiomyopathy. J Clin Invest (1999) 2.19
Electrocardiographic and clinical criteria for recognition of acute myocardial infarction based on analysis of 3,697 patients. Am J Cardiol (1983) 2.18
Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs. J Allergy Clin Immunol (2012) 2.17
Development and implementation of guidelines for family practice: lessons from The Netherlands. J Fam Pract (1995) 2.11
Diagnostic marker cooperative study for the diagnosis of myocardial infarction. Circulation (1999) 2.09
Identification of patients most likely to benefit from implantable cardioverter-defibrillator therapy: the Canadian Implantable Defibrillator Study. Circulation (2000) 2.05
Short and long term prognosis of acute myocardial infarction since introduction of thrombolysis. BMJ (1993) 2.03
Comparison of immediate invasive, delayed invasive, and conservative strategies after tissue-type plasminogen activator. Results of the Thrombolysis in Myocardial Infarction (TIMI) Phase II-A trial. Circulation (1990) 2.01
Isolation and sequence analysis of a full-length cDNA for human M creatine kinase. Biochem Biophys Res Commun (1986) 1.96
Basal insulin therapy in type 2 diabetes: 28-week comparison of insulin glargine (HOE 901) and NPH insulin. Diabetes Care (2001) 1.94
Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog. Proc Natl Acad Sci U S A (1989) 1.90
Integrated patient records: another move towards quality for patients? Qual Health Care (1993) 1.88
Does breastfeeding at six months predict cognitive development? Aust N Z J Public Health (1998) 1.87
Randomized clinical trial of breast irradiation following lumpectomy and axillary dissection for node-negative breast cancer: an update. Ontario Clinical Oncology Group. J Natl Cancer Inst (1996) 1.86
Depression and risk of sudden cardiac death after acute myocardial infarction: testing for the confounding effects of fatigue. Psychosom Med (2000) 1.80
Familial colloid cyst of the third ventricle: case report and review of associated conditions. Neurosurgery (1996) 1.79
An improved basis for enzymatic estimation of infarct size. Circulation (1975) 1.77
Enhancement of theophylline clearance by oral activated charcoal. Clin Pharmacol Ther (1983) 1.76
The influence of location and extent of myocardial infarction on long-term ventricular dysrhythmia and mortality. Circulation (1979) 1.75
ABC of child abuse. Child sexual abuse--II. BMJ (1989) 1.72
Tissue Doppler imaging consistently detects myocardial contraction and relaxation abnormalities, irrespective of cardiac hypertrophy, in a transgenic rabbit model of human hypertrophic cardiomyopathy. Circulation (2000) 1.72
Severity of coronary artery calcification by electron beam computed tomography predicts silent myocardial ischemia. Circulation (2000) 1.70
Magnetic resonance spectroscopy, β-amyloid load, and cognition in a population-based sample of cognitively normal older adults. Neurology (2011) 1.70
Disability, distress and unemployment in neurology outpatients with symptoms 'unexplained by organic disease'. J Neurol Neurosurg Psychiatry (2011) 1.69
Electrocardiographic diagnosis of myocardial infarction in the presence of complete left bundle branch block. Am Heart J (1988) 1.69
Post-myocardial infarction mortality in patients with ventricular premature depolarizations. Canadian Amiodarone Myocardial Infarction Arrhythmia Trial Pilot Study. Circulation (1991) 1.68
Postprandial plasma bile acid responses in normal weight and obese subjects. Ann Clin Biochem (2010) 1.67
Effects of nifedipine on myocardial perfusion and ischemic injury in dogs. Circ Res (1978) 1.67
The struggle to diagnose UTI in children under two in primary care. Fam Pract (1997) 1.65
Deleterious effects of methylprednisolone in patients with myocardial infarction. Circulation (1976) 1.65
Early diagnosis of acute myocardial infarction based on assay for subforms of creatine kinase-MB. Circulation (1990) 1.61
Depression and substance use in minority middle-school students. Am J Public Health (2001) 1.61
Optimal delivery of aerosols from metered dose inhalers. Chest (1981) 1.59
Fibrinolytic variables in patients with recurrent venous thrombosis: a prospective cohort study. Thromb Haemost (2001) 1.58
Unexplained extra visits to general practitioners before the diagnosis of first urinary tract infection: a case-control study. Arch Dis Child (2002) 1.58
Integrated record keeping as an essential aspect of a primary care led health service. BMJ (1998) 1.55
Enhancement of recovery of myocardial function by oxygen free-radical scavengers after reversible regional ischemia. Circulation (1985) 1.54
Ten down under: implementing ICD-10 in Australia. J AHIMA (2000) 1.54
Serial plasma catecholamine response early in the course of clinical acute myocardial infarction: relationship to infarct extent and mortality. Am Heart J (1981) 1.54
Paradoxical endogenous synthesis of a coronary dilating substance from arachidonate. Prostaglandins (1976) 1.52
ABC of child abuse. Child sexual abuse--I. BMJ (1989) 1.52
Autonomous expression of c-myc in BC3H1 cells partially inhibits but does not prevent myogenic differentiation. Mol Cell Biol (1987) 1.52
A prospective study to identify the risk factors associated with acute reactions to platelet and red cell transfusions. Transfusion (1993) 1.52
Quantitative exercise thallium-201 single photon emission computed tomography for the enhanced diagnosis of ischemic heart disease. J Am Coll Cardiol (1990) 1.51
Deleterious effects due to hemorrhage after myocardial reperfusion. Am J Cardiol (1974) 1.51
Role of the dinB gene product in spontaneous mutation in Escherichia coli with an impaired replicative polymerase. J Bacteriol (2000) 1.51
Human eHAND, but not dHAND, is down-regulated in cardiomyopathies. J Mol Cell Cardiol (2001) 1.50
Cyclophosphamide and plasma exchange in multiple sclerosis. Lancet (1991) 1.50
The longitudinal influence of home and neighbourhood environments on children's body mass index and physical activity over 5 years: the CLAN study. Int J Obes (Lond) (2010) 1.49
Human creatine kinase: isolation and sequence analysis of cDNA clones for the B subunit, development of subunit specific probes and determination of gene copy number. Biochem Biophys Res Commun (1987) 1.48
Recent advances in the molecular genetics of hypertrophic cardiomyopathy. Circulation (1995) 1.48
Dominant-negative effect of a mutant cardiac troponin T on cardiac structure and function in transgenic mice. J Clin Invest (1998) 1.47
Effects of low-dose aspirin on in vitro platelet aggregation in the early minutes after ingestion in normal subjects. Am J Cardiol (1994) 1.45
An accurate, nontraumatic ultrasonic method to monitor myocardial wall thickening in patients undergoing cardiac surgery. J Am Coll Cardiol (1990) 1.44
Carcinoma of the gall-bladder producing mucous obstruction of the common bile duct: a cautionary note. J R Coll Surg Edinb (1997) 1.43
Cognitive development and dietary therapy in phenylketonuric children. N Engl J Med (1968) 1.42
Nifedipine therapy for patients with threatened and acute myocardial infarction: a randomized, double-blind, placebo-controlled comparison. Circulation (1984) 1.41
Relation between infarct size and ventricular arrhythmia. Br Heart J (1975) 1.41
Specificity of elevated serum MB creatine phosphokinase activity in the diagnosis of acute myocardial infarction. Am J Cardiol (1975) 1.40
Insulin analogues and their potential in the management of diabetes mellitus. Diabetologia (1999) 1.40
The use of impedance respirometry to confirm tracheal intubation in children. Anaesthesia (2006) 1.40
Effect of symptomless bacteriuria in childhood on subsequent pregnancy. Lancet (1987) 1.40
Therapeutic drug monitoring. Clin Pharmacol Ther (1988) 1.40