Published in Gen Hosp Psychiatry on November 01, 1987
Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis. Cell (1990) 9.21
A method of stimulating different segments of the autonomic outflow from the spinal column to various organs in the pithed cat and rat. Br J Pharmacol (1970) 7.77
Demonstration that CFTR is a chloride channel by alteration of its anion selectivity. Science (1991) 5.82
Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells. Nature (1990) 4.26
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel. Cell (1991) 3.75
Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. Cell (1993) 3.47
Generation of cAMP-activated chloride currents by expression of CFTR. Science (1991) 3.45
Mutations in CFTR associated with mild-disease-form Cl- channels with altered pore properties. Nature (1993) 3.43
Nucleoside triphosphates are required to open the CFTR chloride channel. Cell (1991) 3.21
The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel. J Biol Chem (1994) 2.23
Effect of deleting the R domain on CFTR-generated chloride channels. Science (1991) 2.09
Oxyhaemoglobin blocks non-adrenergic non-cholinergic inhibition in the bovine retractor penis muscle. Eur J Pharmacol (1982) 2.08
Development and analysis of recombinant adenoviruses for gene therapy of cystic fibrosis. Hum Gene Ther (1993) 1.72
Identification and regulation of the cystic fibrosis transmembrane conductance regulator-generated chloride channel. J Clin Invest (1991) 1.71
Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1alpha/VP16 hybrid transcription factor. Circulation (2000) 1.70
Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats. Nat Genet (1994) 1.62
The gene crtI mediates the conversion of phytoene into colored carotenoids in Rhodopseudomonas capsulata. J Biol Chem (1986) 1.61
The effects of drugs on the sensitivity of the rat anococcygeus muscle to agonists. Br J Pharmacol (1973) 1.53
Analytical anion-exchange HPLC of recombinant type-5 adenoviral particles. Hum Gene Ther (1997) 1.50
Cystic fibrosis transmembrane conductance regulator: a chloride channel with novel regulation. Neuron (1992) 1.46
Effect of the E4 region on the persistence of transgene expression from adenovirus vectors. J Virol (1997) 1.46
Neurological decompression sickness treated without recompression. Br Med J (1973) 1.45
Characterization of an adenovirus gene transfer vector containing an E4 deletion. Hum Gene Ther (1995) 1.43
Primary sequence and developmental expression of a novel Drosophila melanogaster src gene. Mol Cell Biol (1987) 1.28
The involvement of corticosteroids in the supersensitivity produced in the rat anococcygeus muscle by morphine withdrawal, thyroidectomy or a single dose of reserpine. J Pharmacol Exp Ther (1975) 1.20
A method of stimulating different segments of the sympathetic and parasympathetic outflows from the spinal cord in the pithed rat. Br J Pharmacol (1969) 1.18
Interaction of ribosomal proteins S6, S8, S15 and S18 with the central domain of 16 S ribosomal RNA from Escherichia coli. J Mol Biol (1984) 1.18
Effects of site-directed mutations in the central domain of 16 S ribosomal RNA upon ribosomal protein binding, RNA processing and 30 S subunit assembly. J Mol Biol (1984) 1.14
Morphine-induced changes in the sensitivity of the isolated colon and vas deferens of the rat. Eur J Pharmacol (1972) 1.13
Mutations within the decoding site of Escherichia coli 16S rRNA: growth rate impairment, lethality and intragenic suppression. Nucleic Acids Res (1988) 1.08
Effect of deletion mutations on the function of CFTR chloride channels. Receptors Channels (1993) 1.06
Exchange transfusion with dextran 40 in polycythaemia secondary to hypoxic lung disease. Br Med J (1971) 1.01
Animal joint behaviour under excessive loading. Nature (1970) 1.01
The effects of electrical stimulation of the autonomic nerves and of drugs on the size of salivary glands and their rate of cell division. J Pharmacol Exp Ther (1975) 1.00
Analysis of muscle coordination strategies in cycling. IEEE Trans Rehabil Eng (2000) 1.00
Barriers to physician-nurse collegiality: an anthropological perspective. Soc Sci Med (1987) 0.98
Ectopic expression of glucagon-like peptide 1 for gene therapy of type II diabetes. Gene Ther (2006) 0.97
Antibody to CD40 ligand inhibits both humoral and cellular immune responses to adenoviral vectors and facilitates repeated administration to mouse airway. Gene Ther (1997) 0.97
Human cystic fibrosis transmembrane conductance regulator directed to respiratory epithelial cells of transgenic mice. Nat Genet (1992) 0.96
Site-directed mutagenesis of the binding site for ribosomal protein S8 within 16S ribosomal RNA from Escherichia coli. Nucleic Acids Res (1986) 0.96
Developmental megalourethra in a monovular twin. Clin Pediatr (Phila) (1965) 0.95
Adenovirus-mediated p53 gene transfer inhibits growth of human tumor cells expressing mutant p53 protein. Cancer Gene Ther (1996) 0.95
Potentiation of gene transfer to the mouse lung by complexes of adenovirus vector and polycations improves therapeutic potential. Hum Gene Ther (1998) 0.94
Alexithymia and somatic amplification in chronic pain. Psychosomatics (1998) 0.94
Somatic instability of carotenoid biosynthesis in the tomato ghost mutant and its effect on plastid development. Planta (1987) 0.93
Acute effects of morphine and opioid peptides on the motility and responses of rat colon to electrical stimulation. Br J Pharmacol (1980) 0.93
Gene therapy for hepatocellular carcinoma: chemosensitivity conferred by adenovirus-mediated transfer of the HSV-1 thymidine kinase gene. Cancer Gene Ther (1995) 0.93
Mapping quantitative trait loci associated with resistance to coccidiosis and growth. Poult Sci (2003) 0.91
Adenovirus-mediated persistent cystic fibrosis transmembrane conductance regulator expression in mouse airway epithelium. J Virol (1998) 0.90
Uniform prehospital data elements and definitions: a report from the uniform prehospital emergency medical services data conference. Ann Emerg Med (1995) 0.89
p53 gene therapy in a rat model of hepatocellular carcinoma: intra-arterial delivery of a recombinant adenovirus. Clin Cancer Res (1998) 0.88
Reliability of the Finger Tapping Test and a note on sex differences. Percept Mot Skills (1979) 0.88
The absence of cocaine- and 6-hydroxydopamine-induced supersensitivity to oxymetazoline in the rat anococcygeus muscle. Br J Pharmacol (1973) 0.88
The rapid lowering of haematocrit by exchange transfusion of Rheomacrodex dextran 40. Its use in polycythaemia, cor pulmonale and ischaemic disease. Acta Med Scand (1971) 0.87
Pre-operation single-dose cefuroxime antimicrobial prophylaxis with and without metronidazole in elective gastrointestinal surgery. J Antimicrob Chemother (1980) 0.87
Technique for treatment of polycythaemia by exchange transfusion. Lancet (1971) 0.87
Inhalant use patterns among Eskimo school children in western Alaska. J Addict Dis (1996) 0.87
Development of FIV-specific cytolytic T-lymphocyte responses in cats upon immunisation with FIV vaccines. Vet Microbiol (1997) 0.87
Exchange transfusion in polycythaemia. Bibl Haematol (1975) 0.86
The possible involvement of Na+ ions in corticosterone-induced hypercontractility in the rat anococcygeus muscle. Br J Pharmacol (1976) 0.86
The effects of corticosteroids on the responses of the anococcygeus and gastrocnemius muscles to nerve stimulation in the pithed rat [proceedings]. Br J Pharmacol (1976) 0.86
External ATP and its analogs activate the cystic fibrosis transmembrane conductance regulator by a cyclic AMP-independent mechanism. J Biol Chem (1994) 0.86
Adenovirus-mediated p53 gene transfer suppresses growth of human glioblastoma cells in vitro and in vivo. Int J Cancer (1996) 0.86
Improved anticoagulant control in patients using home international normalized ratio testing and decision support provided through the Internet. Intern Med J (2011) 0.85
Cystic fibrosis gene therapy using an adenovirus vector: in vivo safety and efficacy in nasal epithelium. Hum Gene Ther (1994) 0.85
Embryonic expression of a Drosophila src gene: alternate forms of the protein are expressed in segmental stripes and in the nervous system. Genes Dev (1989) 0.85
Epithelioid sarcoma--a case report. Clin Exp Dermatol (1986) 0.84
Clonidine and morphine increase [3H]-noradrenaline overflow in mouse vas deferens. Br J Pharmacol (1988) 0.84
E4ORF3 requirement for achieving long-term transgene expression from the cytomegalovirus promoter in adenovirus vectors. J Virol (1999) 0.84
Reduction in the cholinesterase activity of the rat anococcygeus muscle produced by corticosterone. Br J Pharmacol (1975) 0.84
Single dose metronidazole with and without cefuroxime in elective colorectal surgery. Br J Surg (1983) 0.84
Survey of patient satisfaction after Doppler-guided transanal hemorrhoidal dearterialization performed in ambulatory settings. Tech Coloproctol (2013) 0.84
Increased responsiveness of intestinal and vascular smooth muscle to agonists in rats infected with Nippostrongylus brasiliensis. Arch Int Pharmacodyn Ther (1983) 0.83
The microcirculatory effects of peripheral sympathectomy. J Hand Surg Am (1995) 0.83
Geropsychiatric consultation for African-American and Caucasian patients. Gen Hosp Psychiatry (1997) 0.83
Investigation of the effects of drugs on morphine-induced contractions of the isolated colon of the rat [proceedings]. Br J Pharmacol (1976) 0.83
Novel role for E4 region genes in protection of adenovirus vectors from lysis by cytotoxic T lymphocytes. J Virol (1999) 0.83
Use of a monoclonal antibody against an Escherichia coli O26 surface protein for detection of enteropathogenic and enterohemorrhagic strains. Clin Diagn Lab Immunol (1999) 0.82
Proceedings: The involvement of corticosteroids in the supersensitivity produced in the rat anococcygeus muscle by morphine withdrawal or reserpine. Br J Pharmacol (1974) 0.81
Proceedings: Drug-induced changes in the sensitivity of the rat anococcygeus muscle. Br J Pharmacol (1973) 0.81
Engineered mutants of pRB with improved growth suppression potential. Oncogene (1997) 0.81
Antitransferrin receptor antibody-RNase fusion protein expressed in the mammary gland of transgenic mice. J Immunol Methods (1999) 0.81
The effects of drugs or denervation on thymidine uptake into rat regenerating liver. Eur J Pharmacol (1974) 0.81
Enhancement of Fas ligand-induced inhibition of neointimal formation in rabbit femoral and iliac arteries by coexpression of p35. Hum Gene Ther (2001) 0.80
Transmission of shiga toxin-producing Escherichia coli O104:H4 at a family party possibly due to contamination by a food handler, Germany 2011. Epidemiol Infect (2013) 0.79
Analysis of disease resistance-associated parameters in broiler chickens challenged with Eimeria maxima. Poult Sci (2000) 0.79
Construction, expression and characterization of humanized antibodies directed against the human alpha/beta T cell receptor. J Immunol (1991) 0.79
Posttraumatic stress disorder with psychotic features. Am J Psychiatry (1995) 0.78
After traumatic brain injury: a discussion of consequences. Brain Inj (1994) 0.78
Interrelations between age and plasma renin, aldosterone and cortisol, urinary catecholamines, and the body sodium/volume state in normal man. Klin Wochenschr (1977) 0.78
Understanding and coping with neurological impairment. Rehabil Nurs (1995) 0.77
Caregivers of people with multiple sclerosis: a survey in New Zealand. Rehabil Nurs (1996) 0.77
Feline bone marrow transplantation: its use in FIV-infected cats. Vet Immunol Immunopathol (1998) 0.77
Application of a monoclonal antibody-based enzyme-linked immunosorbent assay for detection of an inflammatory response antigen in subclinical mastitic milk samples. J Clin Microbiol (1991) 0.77
Production of cystic fibrosis transmembrane conductance regulator in the milk of transgenic mice. Biotechnology (N Y) (1992) 0.77
Structure-function analysis of tissue-type plasminogen activator by linker-insertion, point and deletion mutagenesis. Protein Eng (1989) 0.77
A behavior checklist for use in child psychiatry clinics. J Am Acad Child Psychiatry (1968) 0.76
An approach to teaching the introduction to clinical medicine. Ann Intern Med (1976) 0.76
Benztropine in the treatment of venlafaxine-induced sweating. J Clin Psychiatry (1997) 0.76