Published in Mol Cell Biochem on April 02, 1979
5-Azacytidine, a new, highly effective cancerostatic. Experientia (1964) 1.84
Biological effects of 5-azacytidine in eukaryotes. Oncology (1974) 1.54
Incorporation of a potent antileukemic agent, 5-aza-2'-deoxycytidine, into DNA of cells from leukemic mice. Cancer Res (1977) 1.01
Azapyrimidine nucleosides: metabolism and inhibitory mechanisms. Adv Enzyme Regul (1985) 0.93
Characteristics of mouse leukemic cells resistant to 5-azacytidine and 5-aza-2'-deoxycytidine. Cancer Res (1968) 0.93
Association of decreased uridine and deoxycytidine kinase with enhanced RNA and DNA polymerase in mouse leukemic cells resistant to 5-azacytidine and 5-aza-2'-deoxycytidine. Cancer Res (1970) 0.88
Prolongation of the lag period preceding the enhancement of thymidine and thymidylate kinase activity in regenerating rat liver by 5-azacytidine. Biochem Pharmacol (1972) 0.87
Characterization of polyribosomes and maturation of ribosomal RNA in hepatoma cells treated with 5-azacytidine. Cancer Res (1974) 0.85
Enhanced stability of uridine kinase from mouse leukemic cells resistant to 5-azacytidine. Thermal inactivation and effect of p-chloromercuribenzoate. Eur J Biochem (1971) 0.84
Decreased synthesis of DNA in regenerating rat liver after the administration of reserpine. Br J Pharmacol (1973) 0.84
Biochemical mechanisms of drug resistance. IV. Development of resistance to 5-azacytidine and simultaneous depression of pyrimidine metabolism in leukemic mice. Int J Cancer (1967) 0.84
Synthesis of DNA in the liver and testes of cadmium-tested partially hepatectomized rats. J Biochem (1979) 0.83
Incorporation of 5-azacytidine into liver ribonucleic acids of leukemic mice sensitive and resistant to 5-azacytidine. Biochim Biophys Acta (1965) 0.82
Enhanced uridine kinase in rat liver following 5-azacytidine administration. In vivo characterization and properties of partially purified enzyme. J Biol Chem (1973) 0.80
Effects of 5-azacytidine on hepatic polyribosomes and maturation of ribosomal RNA. Acta Biol Med Ger (1974) 0.80
Uridine kinase: properties, biological significance and chemotherapeutic aspects (a review). Neoplasma (1976) 0.79
Effect of 5-azacytidine and 6-azauridine on the synthesis of DNA in embryonic mouse brain mitotic activity and migration of ventricular cells. Neoplasma (1973) 0.78
Resistance of mammalian tumour cells toward pyrimidine analogues. A review. Oncology (1973) 0.77
Inhibitory effect of various cytostatics and cycloheximide on acute experimental pancreatitis in rats. Gut (1977) 0.77
Impaired gastric secretion in rats treated with 5-azacytidine. Arch Int Pharmacodyn Ther (1974) 0.77
Metabolic alterations of liver regeneration. 8. Enhanced synthesis of DNA in the liver of 5-azacytidine-treated rats subjected to partial hepatectomy. Int J Cancer (1972) 0.77
Metabolic transformations of 5-azaorotate: cause of marked inhibition of orotidine-5'-phosphate decarboxylase. Biochim Biophys Acta (1967) 0.77
5-Aza-2'-deoxycytidine: preclinical studies in mice. Neoplasma (1980) 0.77
[Possibilities for the clinical use of 5-azacytidine]. Vopr Onkol (1977) 0.76
Biochemical mechanism of drug resistance. VII. Inhibition of orotic acid metabolism by 5-azacytidine in leukemic mice sensitive and resistant to 5-azacytidine. Biochem Pharmacol (1968) 0.76
The role of putrescine in modulation of DNA synthesis in regenerating liver of rats pretreated with 5-azacytidine. J Biochem (1981) 0.76
High-frequency induction in vivo of mouse leukemia in AKR strain by 5-azacytidine and 5-iodo-2'-deoxyuridine. Experientia (1973) 0.76
Depressed synthesis of DNA in regenerating rat liver after spinal cord (C7) transection. Experientia (1973) 0.75
Uridine kinase in embryonic rat liver. Modulation of enzyme activity by 5-azacytidine. Biochem J (1973) 0.75
Effect of 5-azacytidine and its derivatives on gastric secretion. Pharmacol Ther (1985) 0.75
Thymidine kinase and polyribosome distribution in regerating rat liver following 5-azacytidine. Biochim Biophys Acta (1968) 0.75
Enhanced incorporation of thymidine into DNA in the liver of intact and partially hepatectomized rats pretreated with 5-azacytidine. Cancer Res (1976) 0.75
[5-azacytidine and synthesis of purine nucleotides in cerebral cortex slices from guinea pigs by a salvage pathway from adenine (author's transl)]. Bratisl Lek Listy (1979) 0.75
Enhancement of rat liver uridine kinase activity by various metabolic inhibitors. Biochem Pharmacol (1974) 0.75
Inhibition of phytohemagglutinin-induced DNA synthesis and of adenosine deamination by 5-azacytidine and 5-aza-2'-deoxycytidine in intact human cells. Neoplasma (1985) 0.75
Depression of experimental gastric ulcers and acute pancreatitis in rats treated by 5-azacytosine, 5-azacytidine and their N-methyl derivatives. Experientia (1986) 0.75
Inhibition of bovine heart adenosine deaminase activity by some pyrimidine analogues. Neoplasma (1983) 0.75
Labeling of cytoplasmic liver RNA by (6- 14 C)orotic and 5-fluoro(2- 14 C)orotic acids. Effect of several inhibitors. Eur J Biochem (1973) 0.75
Synthesis and biological activity of 2'-deoxy-6-methyl-5-azacytidine and its alpha-D-anomer. Nucleic Acids Symp Ser (1981) 0.75
Localization of the labelled 5-azacytidine in cultured mouse embryonic cells. Experientia (1974) 0.75
Metabolism of 9-(S)-(2,3-dihydroxypropyl)adenine, an antiviral agent, in mice. Biochem Pharmacol (1981) 0.75
Stimulatory effect of cycloheximide and related glutarimide antibiotics on liver uridine kinase. FEBS Lett (1972) 0.75
Effects of N4-methyl and N4,N4-dimethyl derivatives of 5-azacytidine on liver RNA synthesis and gastric secretion in rats. Neoplasma (1985) 0.75
[Safargam 67 and its tensile and compression strength]. Cesk Stomatol (1966) 0.75
Effects of 5-aza-2'-deoxycytidine on DNA synthesis in mouse lymphatic tissues. Neoplasma (1978) 0.75
Biochemical mechanisms of drug resistance. XII. Uridine kinases from mouse leukemic cells sensitive and resistant to 5-azacytidine. Int J Cancer (1971) 0.75
Effect of 5-aza-2'-deoxycytidine on antibody formation and DNA synthesis in rat spleen. Z Naturforsch C (1980) 0.75
Inhibitory effect of cycloheximide on gastric secretion in rats. Biochem Pharmacol (1977) 0.75
Biochemical changes associated with the development of resistance to 5-azacytidine in AKR leukemic mice. Int J Cancer (1966) 0.75
Transformation of 5-aza-2'-deoxycytidine-3H and its incorporation in different systems of rapidly proliferating cells. Eur J Cancer (1978) 0.75
Coprecipitation of active uridine kinase and phosphomonoesterase from rat kidney by Zn2+-ions. III. Enzymes relevant to cancer chemotherapy. Chem Biol Interact (1977) 0.75
Lower gastric secretion and higher incorporation of orotic acid into liver RNA in rats treated with 5-azacytidine and cycloheximide. Neoplasma (1978) 0.75
[5-azacytidine and new formation of purine nucleotides, RNA, proteins, and lipids in the cerebral cortex of guinea pigs (author's transl)]. Bratisl Lek Listy (1979) 0.75
Inhibitory effects of 5-azapyrimidine nucleosides on cellular immunity. Immunobiology (1982) 0.75
Stimulatory effect of 5-azacytidine on 7S antibody production on rats. Proc Soc Exp Biol Med (1978) 0.75
Metabolic alterations of liver regeneration. XV. Cadmium-mediated depression of thymidine and thymidylate kinase induction in rats. Chem Biol Interact (1979) 0.75
Transformation of 5-aza-2'-(3H)deoxycytidine in Escherichia coli. FEBS Lett (1977) 0.75
Enhanced mortality in offsprings of male mice treated with 5-azacytidine prior to mating. Morphological changes in testes. Neoplasma (1976) 0.75
[Skin fistuals of dental origin]. Rozhl Chir (1969) 0.75
Modulation of cell-mediated immunity with 5-azapyrimidine nucleosides. Czech Med (1987) 0.75
Exocrine pancreatic enzymes in cycloheximide treated rats. Experientia (1976) 0.75
[Effect of some cytostatics and cycloheximide on the activity of pancreatic enzymes in the experiment on rats (author's transl)]. Sb Lek (1978) 0.75
Biochemical mechanisms of drug resistance. 3. Differences in the metabolism of mouse leukaemic cells sensitive and resistant to 5-azacytidine. Acta Biochim Pol (1966) 0.75
Tryptophan-mediated induction of hepatic enzymes stimulated by 5-azacytidine pretreatment. Biomedicine (1981) 0.75
Effects of 5-azacytidine on dietary and hormone induction of serine dehydratase and tyrosine aminotransferase in rat liver. Biochem Pharmacol (1972) 0.75
Dual effect of 5-azacytidine on the synthesis of liver ribonucleic acids. Lack of the relationship between metabolic transformation of orotic acid in vitro and its incorporation in vivo. Biochem Pharmacol (1972) 0.75
Pycnotic degeneration of ventricular cells in embryonic brain following transplacental exposure to 5-azacytidine. Experientia (1972) 0.75
Pb-precipitated protein fraction from calf brain containing highly active uridine kinase with different molecular properties. FEBS Lett (1975) 0.75
[Mechanism of cystostatic effect of 5-azacytidine and its usefulness in clinic]. Cas Lek Cesk (1975) 0.75
Kinetics of 5-aza-2'-deoxycytidine phosphorylation in mouse spleen and L1210 leukemic cell extracts. Neoplasma (1980) 0.75
Biotransformation and some metabolic effects of 5-(4-aminophenyl)-cytosine. Biochem Pharmacol (1967) 0.75
Effects of cycloheximide and streptovitacin A on protein synthesis and gastric secretion in rats. J Antibiot (Tokyo) (1978) 0.75
Depression of DNA synthesis in mouse spleen after treatment with 5-aza-2'-deoxycytidine. J Natl Cancer Inst (1979) 0.75
Metabolic transformations of 5-azauracil and 5-azaorotic acid in mouse liver and Escherichia coli. Effect on the synthesis of pyrimidines. Biochem Pharmacol (1972) 0.75
Effect of different factors on liver thymidine monophosphate kinase in vivo and the synthesis of thymidine 5'-triphosphate in vitro. Acta Biochim Pol (1972) 0.75
Modulatory effect of cytostatics and chemical carcinogens on liver regeneration (a review). Neoplasma (1974) 0.75
Stimulated DNA synthesis in livers and kidneys induced to proliferate associated with unchanged thymidine and thymidylate kinase activities. Chem Biol Interact (1976) 0.75
Radioprotective effect of 5-azacytidine in AKR mice. Z Naturforsch B (1969) 0.75
[Participation of toxoplasmosis in the etiology of chronic tonsillitis (author's transl)]. Bratisl Lek Listy (1977) 0.75
Stability of the insoluble form of uridine kinase coupled to zn2+ or pb2+ ions. Hoppe Seylers Z Physiol Chem (1976) 0.75