Published in Proc Natl Acad Sci U S A on May 01, 1985
Cloning and sequencing of the pertussis toxin genes: operon structure and gene duplication. Proc Natl Acad Sci U S A (1986) 5.59
Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP-ribosyltransferase. EMBO J (1990) 3.62
Tumor cell autocrine motility factor. Proc Natl Acad Sci U S A (1986) 2.28
Foetal-calf serum stimulates a pertussis-toxin-sensitive high-affinity GTPase activity in rat glioma C6 BU1 cells. Biochem J (1987) 1.49
Bordetella pertussis adenylate cyclase: effects of affinity-purified adenylate cyclase on human polymorphonuclear leukocyte functions. Infect Immun (1987) 1.48
Metallothionein mediates leukocyte chemotaxis. BMC Immunol (2005) 1.06
Treatment of human platelets with trypsin, thrombin, or collagen inhibits the pertussis toxin-induced ADP-ribosylation of a 41-kDa protein. Proc Natl Acad Sci U S A (1986) 1.06
Regulation of the affinity state of the N-formylated peptide receptor of neutrophils: role of guanine nucleotide-binding proteins and the cytoskeleton. J Cell Biol (1987) 1.05
Bacterial toxins affect early events of T lymphocyte activation. J Clin Invest (1989) 1.02
Cholera toxin inhibits chemotaxis by a cAMP-independent mechanism. Proc Natl Acad Sci U S A (1985) 1.01
Role of G-proteins in T cell activation: non-hydrolysable GTP analogues induce early ornithine decarboxylase activity in human T lymphocytes. EMBO J (1986) 0.87
Stimulation of phosphoinositide metabolism in hamster brown adipocytes exposed to alpha 1-adrenergic agents and its inhibition with phorbol esters. Biochem J (1986) 0.85
Adjuvant immunotherapy of C6 glioma in rats with pertussis toxin. J Cancer Res Clin Oncol (2011) 0.80
Effects of adenylate cyclase toxin from Bordetella pertussis on human neutrophil interactions with Coccidioides immitis and Staphylococcus aureus. Infect Immun (1988) 0.79
Inhibition of formation of cyclic AMP and cyclic GMP by vasopressin in smooth-muscle cells is insensitive to pertussis toxin. Biochem J (1988) 0.78
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81
High resolution two-dimensional electrophoresis of proteins. J Biol Chem (1975) 133.45
G proteins and dual control of adenylate cyclase. Cell (1984) 11.05
N-formylmethionyl peptides as chemoattractants for leucocytes. Proc Natl Acad Sci U S A (1975) 9.24
Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain. J Biol Chem (1984) 6.58
Functional macrophage cell lines transformed by Abelson leukemia virus. Cell (1978) 5.76
Direct modification of the membrane adenylate cyclase system by islet-activating protein due to ADP-ribosylation of a membrane protein. Proc Natl Acad Sci U S A (1982) 5.68
Flow of information in the light-triggered cyclic nucleotide cascade of vision. Proc Natl Acad Sci U S A (1981) 4.87
Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase. J Biol Chem (1984) 3.82
Pertussis toxin. Affinity purification of a new ADP-ribosyltransferase. J Biol Chem (1983) 3.31
Morphine receptors as regulators of adenylate cyclase activity. Proc Natl Acad Sci U S A (1975) 3.10
ADP ribosylation of the specific membrane protein of C6 cells by islet-activating protein associated with modification of adenylate cyclase activity. J Biol Chem (1982) 3.04
Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin. Cell (1984) 2.96
Evidence for an S-adenosylmethionine requirement in the chemotactic behavior of Salmonella typhimurium. J Mol Biol (1975) 2.76
Purification and properties of the inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. J Biol Chem (1984) 2.56
ADP-ribosylation of transducin by pertussis toxin blocks the light-stimulated hydrolysis of GTP and cGMP in retinal photoreceptors. J Biol Chem (1984) 2.39
The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Properties and function of the purified protein. J Biol Chem (1984) 2.05
Specific uncoupling by islet-activating protein, pertussis toxin, of negative signal transduction via alpha-adrenergic, cholinergic, and opiate receptors in neuroblastoma x glioma hybrid cells. J Biol Chem (1983) 1.98
Loss of the inhibitory function of the guanine nucleotide regulatory component of adenylate cyclase due to its ADP ribosylation by islet-activating protein, pertussis toxin, in adipocyte membranes. J Biol Chem (1983) 1.97
Requirement of S-adenosyl-L-methionine-mediated methylation for human monocyte chemotaxis. Proc Natl Acad Sci U S A (1978) 1.89
The inhibitory guanine nucleotide-binding protein (Ni) purified from bovine brain is a high affinity GTPase. J Biol Chem (1985) 1.83
Guanine nucleotides modulate the binding affinity of the oligopeptide chemoattractant receptor on human polymorphonuclear leukocytes. J Clin Invest (1983) 1.73
The oligopeptide chemotactic factor receptor on human polymorphonuclear leukocyte membranes exists in two affinity states. Biochem Biophys Res Commun (1982) 1.72
Pertussis toxin inhibits the rise in the intracellular concentration of free calcium that is induced by chemotactic factors in rabbit neutrophils: possible role of the "G proteins" in calcium mobilization. Biochem Biophys Res Commun (1984) 1.72
Pertussis toxin substrate, the putative Ni component of adenylyl cyclases, is an alpha beta heterodimer regulated by guanine nucleotide and magnesium. Proc Natl Acad Sci U S A (1983) 1.67
The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Subunit dissociation and the inhibition of adenylate cyclase in S49 lymphoma cyc- and wild type membranes. J Biol Chem (1984) 1.62
Slow interaction of islet-activating protein with pancreatic islets during primary culture to cause reversal of alpha-adrenergic inhibition of insulin secretion. J Biol Chem (1980) 1.61
Induction of a transient elevation in intracellular levels of adenosine-3',5'-cyclic monophosphate by chemotactic factors: an early event in human neutrophil activation. J Immunol (1980) 1.54
Increased levels of cyclic adenosine-3',5'-monophosphate in human polymorphonuclear leukocytes after surface stimulation. J Clin Invest (1980) 1.36
Adaptation of human neutrophil responsiveness to the chemoattractant N-formylmethionylleucylphenylalanine. Heterogeneity and/or negative cooperative interaction of receptors. J Biol Chem (1982) 1.28
The formylpeptide chemotactic receptor on rabbit peritoneal neutrophils. I. Evidence for two binding sites with different affinities. J Immunol (1982) 1.27
Chemotaxis by mouse macrophage cell lines. J Immunol (1981) 1.14
Pertussis toxin catalyzes the ADP-ribosylation of two distinct peptides, 40 and 41 kDa, in rat fat cell membranes. FEBS Lett (1984) 1.13
In vitro inhibition of murine macrophage migration by Bordetella pertussis lymphocytosis-promoting factor. Infect Immun (1984) 1.12
Inhibition of chemotaxis by S-3-deazaadenosylhomocysteine in a mouse macrophage cell line. J Biol Chem (1982) 1.07
Lymphocytosis-promoting factor of Bordetella pertussis alters mononuclear phagocyte circulation and response to inflammation. Infect Immun (1984) 1.07
Transmethylation reactions regulate affinity and functional activity of chemotactic factor receptors on macrophages. Cell (1982) 1.03
Modulation of sodium-sensitive GTPase by partial opiate agonists. An explanation for the dual requirement for Na+ and GTP in inhibitory regulation of adenylate cyclase. J Biol Chem (1982) 1.00
Promotion of lipolysis in rat adipocytes by pertussis toxin: reversal of endogenous inhibition. Proc Natl Acad Sci U S A (1983) 0.98
Evidence for N-formyl chemotactic peptide-stimulated GTPase activity in human neutrophil homogenates. FEBS Lett (1984) 0.97
Oxidized N-formylmethionyl-leucyl-phenylalanine: effect on the activation of human monocyte and neutrophil chemotaxis and superoxide production. J Immunol (1984) 0.90
Chemotaxin-induced changes in cyclic adenosine monophosphate levels in human neutrophils. Infect Immun (1980) 0.87
Chemotaxis and the synthesis of specific proteins are inhibited by 3-deazaadenosine and other adenosine analogs in a mouse macrophage cell line. J Biol Chem (1983) 0.87
Nature and rates of adverse reactions associated with DTP and DT immunizations in infants and children. Pediatrics (1981) 7.58
Extracytoplasmic adenylate cyclase of Bordetella pertussis. Proc Natl Acad Sci U S A (1976) 3.57
Pertussis toxin. Affinity purification of a new ADP-ribosyltransferase. J Biol Chem (1983) 3.31
Separation and purification of the hemagglutinins from Bordetella pertussis. Infect Immun (1983) 2.85
Role of antibody to leukocytosis-promoting factor hemagglutinin and to filamentous hemagglutinin in immunity to pertussis. Infect Immun (1981) 2.77
Identification of a 69-kilodalton nonfimbrial protein as an agglutinogen of Bordetella pertussis. Infect Immun (1988) 2.55
Biological methylation: selected aspects. Annu Rev Biochem (1975) 2.53
THE CARDIOTOXIC ACTION OF PREPARATIONS CONTAINING THE OXYGEN-LABILE HEMOLYSIN OF STREPTOCOCCUS PYOGENES : I. INCREASED SENSITIVITY OF THE ISOLATED FROG'S HEART TO REPEATED APPLICATION OF THE TOXIN. J Exp Med (1945) 2.50
ADP-ribosylation of transducin by pertussis toxin blocks the light-stimulated hydrolysis of GTP and cGMP in retinal photoreceptors. J Biol Chem (1984) 2.39
The Sézary syndrome: a malignant proliferation of helper T cells. J Clin Invest (1976) 2.32
Aerosol infection of mice with Bordetella pertussis. Infect Immun (1980) 2.31
Phase-shift markers in Bordetella: alterations in envelope proteins. J Infect Dis (1981) 2.23
Comparison of 13 acellular pertussis vaccines: overview and serologic response. Pediatrics (1995) 2.20
Filamentous hemagglutinin has a major role in mediating adherence of Bordetella pertussis to human WiDr cells. Infect Immun (1986) 2.18
Identification of the ribose binding protein as the receptor for ribose chemotaxis in Salmonella typhimurium. Biochemistry (1974) 2.09
Protective activities of the filamentous hemagglutinin and the lymphocytosis-promoting factor of Bordetella pertussis in mice. J Infect Dis (1984) 1.96
Collaborative study for the evaluation of enzyme-linked immunosorbent assays used to measure human antibodies to Bordetella pertussis antigens. Clin Diagn Lab Immunol (1996) 1.94
Sensitivity and specificity of clinical case definitions for pertussis. Am J Public Health (1988) 1.93
Comparison of type 2 and type 6 fimbriae of Bordetella pertussis by using agglutinating monoclonal antibodies. Infect Immun (1988) 1.92
Lectin-like binding of pertussis toxin to a 165-kilodalton Chinese hamster ovary cell glycoprotein. J Biol Chem (1988) 1.88
Intracellular localization of the dermonecrotic toxin of Bordetella pertussis. Infect Immun (1979) 1.83
Replacement of 5-methylcytosine by cytosine: a possible mechanism for transient DNA demethylation during differentiation. Proc Natl Acad Sci U S A (1986) 1.79
Evaluation of pertussis in U.S. Marine Corps trainees. Clin Infect Dis (1997) 1.79
Serological response to filamentous hemagglutinin and lymphocytosis-promoting toxin of Bordetella pertussis. Infect Immun (1983) 1.77
Agglutinating monoclonal antibodies that specifically recognize lipooligosaccharide A of Bordetella pertussis. Infect Immun (1988) 1.71
Immunologic response to early and routine DTP immunization in infants. Pediatrics (1984) 1.71
Binding of pertussis toxin to eucaryotic cells and glycoproteins. Infect Immun (1989) 1.71
Pertussis toxin substrate, the putative Ni component of adenylyl cyclases, is an alpha beta heterodimer regulated by guanine nucleotide and magnesium. Proc Natl Acad Sci U S A (1983) 1.67
Characterization of the protective capacity and immunogenicity of the 69-kD outer membrane protein of Bordetella pertussis. J Exp Med (1990) 1.67
Consensus nomenclature for the mammalian methionine adenosyltransferase genes and gene products. Trends Genet (1997) 1.67
Infants and children with convulsions and hypotonic-hyporesponsive episodes following diphtheria-tetanus-pertussis immunization: follow-up evaluation. Pediatrics (1988) 1.66
Methionine synthesis from 5'-methylthioadenosine in rat liver. J Biol Chem (1981) 1.63
Ns and Ni, the stimulatory and inhibitory regulatory components of adenylyl cyclases. Purification of the human erythrocyte proteins without the use of activating regulatory ligands. J Biol Chem (1984) 1.62
Stimulation and inhibition of adenylyl cyclases mediated by distinct regulatory proteins. Nature (1983) 1.59
Nonfermentative bacilli associated with man. I. Nomenclature. Am J Clin Pathol (1970) 1.57
Role of the A subunit of pertussis toxin in alteration of Chinese hamster ovary cell morphology. Infect Immun (1987) 1.52
Identification of Bordetella pertussis infection by shared-primer PCR. J Clin Microbiol (1994) 1.49
Inhibition of promoter activity by methylation: possible involvement of protein mediators. Proc Natl Acad Sci U S A (1991) 1.47
Purification and characterization of fimbriae isolated from Bordetella pertussis. Infect Immun (1985) 1.47
The reverse cumulative distribution plot: a graphic method for exploratory analysis of antibody data. Pediatrics (1995) 1.46
Monoclonal antibodies to pertussis toxin: utilization as probes of toxin function. Hybridoma (1989) 1.43
A comparison of laboratory and clinical methods for diagnosing pertussis in an outbreak in a facility for the developmentally disabled. J Infect Dis (1988) 1.37
Structural characterization of pertussis toxin A subunit. J Biol Chem (1987) 1.36
Immune response to the B oligomer of pertussis toxin. Infect Immun (1987) 1.36
Activation of methionine for transmethylation. Purification of the S-adenosylmethionine synthetase of bakers' yeast and its separation into two forms. J Biol Chem (1977) 1.33
Epitopes on the S1 subunit of pertussis toxin recognized by monoclonal antibodies. Infect Immun (1989) 1.32
Studies on a calf thymus ribonuclease specific for ribonucleic acid-deoxyribonucleic acid hybrids. Biochemistry (1973) 1.29
Amino acid sequence of S-adenosyl-L-homocysteine hydrolase from rat liver as derived from the cDNA sequence. Proc Natl Acad Sci U S A (1987) 1.28
Plasmodium falciparum: antimalarial activity in culture of sinefungin and other methylation inhibitors. Exp Parasitol (1980) 1.28
Pertussis encephalopathy with a normal brain biopsy and elevated lymphocytosis-promoting factor antibodies. Pediatr Infect Dis (1984) 1.25
The G protein connection: molecular basis of membrane association. Trends Biochem Sci (1991) 1.23
Purification of heterotrimeric GTP-binding proteins from brain: identification of a novel form of Go. Biochemistry (1988) 1.22
Macrophage cell lines produce a cytotoxin. J Immunol (1979) 1.22
S-Adenosyl-L-homocysteine hydrolase: analogues of S-adenosyl-L-homocysteine as potential inhibitors. Mol Pharmacol (1977) 1.21
Identification of 2-keto-4-methylthiobutyrate as an intermediate compound in methionine synthesis from 5'-methylthioadenosine. J Biol Chem (1982) 1.21
Perturbation of biochemical transmethylations by 3-deazaadenosine in vivo. Biochem Pharmacol (1979) 1.17
Reciprocal regulation of Gs alpha by palmitate and the beta gamma subunit. Proc Natl Acad Sci U S A (1996) 1.17
Adenine nucleotides promote dissociation of pertussis toxin subunits. J Biol Chem (1986) 1.17
Adenosylhomocysteine hydrolase inhibitors: synthesis of 5'-deoxy-5'-(isobutylthio)-3-deazaadenosine and its effect on Rous sarcoma virus and Gross murine leukemia virus. Biochem Biophys Res Commun (1978) 1.15
5'-Methylthioadenosine nucleosidase. Purification and characterization of the enzyme from Lupinus luteus seeds. Eur J Biochem (1981) 1.14
Studies concerning the interaction of serine soluble ribonucleic acid with seryl soluble ribonucleic acid synthetase from baker's yeast. Biochemistry (1966) 1.14
Chemotaxis by mouse macrophage cell lines. J Immunol (1981) 1.14
Cloning and sequencing of the structural gene for the porin protein of Bordetella pertussis. Mol Microbiol (1991) 1.13
In vitro inhibition of murine macrophage migration by Bordetella pertussis lymphocytosis-promoting factor. Infect Immun (1984) 1.12
Adenosine analogues as substrates and inhibitors of S-adenosylhomocysteine hydrolase. Biochemistry (1981) 1.12
Carbocyclic analogue of 3-deazaadenosine: a novel antiviral agent using S-adenosylhomocysteine hydrolase as a pharmacological target. J Med Chem (1982) 1.12
Biphasic effect of pertussis vaccine on serum insulin in mice. Infect Immun (1983) 1.11
Purification and characterization of serotype 6 fimbriae from Bordetella pertussis and comparison of their properties with serotype 2 fimbriae. Infect Immun (1987) 1.10
Phase-shift markers in the genus Bordetella: loss of cytochrome d-629 in phase IV variants. Microbios (1981) 1.10
Stimulation of the thiol-dependent ADP-ribosyltransferase and NAD glycohydrolase activities of Bordetella pertussis toxin by adenine nucleotides, phospholipids, and detergents. Biochemistry (1986) 1.10
Adenosylhomocysteine hydrolase. Crystallization of the purified enzyme and its properties. J Biol Chem (1978) 1.09
Yeast STE14 methyltransferase, expressed as TrpE-STE14 fusion protein in Escherichia coli, for in vitro carboxylmethylation of prenylated polypeptides. Methods Enzymol (1995) 1.09
Mechanism of pertussis toxin B oligomer-mediated protection against Bordetella pertussis respiratory infection. Infect Immun (1990) 1.08
Methylation in the preinitiation domain suppresses gene transcription by an indirect mechanism. Proc Natl Acad Sci U S A (1992) 1.08
Inhibition of chemotaxis by S-3-deazaadenosylhomocysteine in a mouse macrophage cell line. J Biol Chem (1982) 1.07
Lymphocytosis-promoting factor of Bordetella pertussis alters mononuclear phagocyte circulation and response to inflammation. Infect Immun (1984) 1.07
Molecular cloning, sequence analysis, and expression in Escherichia coli of the cDNA for guanidinoacetate methyltransferase from rat liver. Proc Natl Acad Sci U S A (1988) 1.06
Regulation of Bordetella pertussis extracytoplasmic adenylate cyclase. Adv Cyclic Nucleotide Res (1978) 1.06
Pertussis in a previously immunized child with human immunodeficiency virus infection. J Pediatr (1989) 1.05
Human serologic response to envelope-associated proteins and adenylate cyclase toxin of Bordetella pertussis. J Infect Dis (1991) 1.04
Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of Gi- and Gq-mediated signaling. J Biol Chem (1999) 1.03
3-Deazaadenosine, an inhibitor of adenosylhomocysteine hydrolase, inhibits reproduction of Rous sarcoma virus and transformation of chick embryo cells. Virology (1978) 1.03
A safety and immunogenicity comparison of 12 acellular pertussis vaccines and one whole-cell pertussis vaccine given as a fourth dose in 15- to 20-month-old children. Pediatrics (1997) 1.03
Purification of serotype 2 fimbriae of Bordetella pertussis and their identification as a mouse protective antigen. Dev Biol Stand (1985) 1.02
Relationship between transient DNA hypomethylation and erythroid differentiation of murine erythroleukemia cells. Proc Natl Acad Sci U S A (1988) 1.01
Effects of the S-adenosylhomocysteine hydrolase inhibitors 3-deazaadenosine and 3-deazaaristeromycin on RNA methylation and synthesis. Eur J Biochem (1986) 1.01
Cholera toxin inhibits chemotaxis by a cAMP-independent mechanism. Proc Natl Acad Sci U S A (1985) 1.01
Extensive swelling after booster doses of acellular pertussis-tetanus-diphtheria vaccines. Pediatrics (2000) 1.00