| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Vasoactive intestinal peptide and watery-diarrhoea syndrome.
|
Lancet
|
1973
|
3.22
|
|
2
|
Possible dual role for vasoactive intestinal peptide as gastrointestinal hormone and neurotransmitter substance.
|
Lancet
|
1976
|
3.08
|
|
3
|
Hypertrophic obstructive cardiomyopathy, a histological, histochemical, and ultrastructural study of biopsy material.
|
Cardiovasc Res
|
1971
|
2.84
|
|
4
|
Neuron-specific enolase is produced by neuroendocrine tumours.
|
Lancet
|
1981
|
2.63
|
|
5
|
Two types of Zollinger-Ellison syndrome: immunofluorescent, cytochemical and ultrastructural studies of the antral and pancreatic gastrin cells in different clinical states.
|
Gut
|
1972
|
2.21
|
|
6
|
Pancreatic polypeptide in insulinomas, gastrinomas, vipomas, and glucagonomas.
|
Lancet
|
1976
|
2.13
|
|
7
|
The endocrine polypeptide cells of the human stomach, duodenum, and jejunum.
|
Gut
|
1970
|
2.10
|
|
8
|
Growth-hormone release-inhibiting hormone in gastrointestinal and pancreatic D cells.
|
Lancet
|
1975
|
2.04
|
|
9
|
Common cytochemical and ultrastructural characteristics of cells producing polypeptide hormones (the APUD series) and their relevance to thyroid and ultimobranchial C cells and calcitonin.
|
Proc R Soc Lond B Biol Sci
|
1968
|
2.01
|
|
10
|
The genesis of apudamyloid in endocrine polypeptide tumours: histochemical distinction from immunamyloid.
|
Virchows Arch B Cell Pathol
|
1972
|
1.83
|
|
11
|
Bifunctional reagents as vapour- and liquid-phase fixatives for immunohistochemistry.
|
Histochem J
|
1975
|
1.80
|
|
12
|
Enkephalin-like immunoreactivity in the human gastrointestinal tract.
|
Lancet
|
1977
|
1.75
|
|
13
|
Immunofluorescent localization of secretin in the canine duodenum.
|
Gut
|
1971
|
1.73
|
|
14
|
Bombesin-like immunoreactivity in the lung.
|
Nature
|
1978
|
1.73
|
|
15
|
Immunofluorescence studies on the distribution of gastrin cells in different clinical states.
|
Gut
|
1970
|
1.71
|
|
16
|
The diffuse neuroendocrine system and the apud concept: related "endocrine" peptides in brain, intestine, pituitary, placenta, and anuran cutaneous glands.
|
Med Biol
|
1977
|
1.68
|
|
17
|
A histochemical study on the role of lysosomal enzymes in idiopathic steatorrhoea before and during a gluten-free diet.
|
Gut
|
1966
|
1.61
|
|
18
|
The APUD cell concept and its implications in pathology.
|
Pathol Annu
|
1974
|
1.58
|
|
19
|
Immunocytochemical localization of substance P in mammalian intestine.
|
Histochemistry
|
1975
|
1.55
|
|
20
|
Response of the jejunal mucosa in adult coeliac disease to oral prednisolone.
|
Gut
|
1970
|
1.54
|
|
21
|
Immunofluorescent localization of the gastrin-secreting G cells in the pyloric antrum of the pig.
|
Histochemie
|
1970
|
1.51
|
|
22
|
Nesidioblastosis: the pathologic basis of persistent hyperinsulinemic hypoglycemia in infants. Morphologic and quantitative analysis of seven cases based on specific immunostaining and electron microscopy.
|
Diabetes
|
1977
|
1.50
|
|
23
|
Specific localisation of neurotensin to the N cell in human intestine by radioimmunoassay and immunocytochemistry.
|
Nature
|
1977
|
1.47
|
|
24
|
Antral-gastrin-cell hyperplasia in peptic-ulcer disease.
|
Lancet
|
1974
|
1.46
|
|
25
|
Amyloid in polypeptide hormone-producing tumors.
|
Lab Invest
|
1977
|
1.45
|
|
26
|
Pancreatic cholera due to production of gastric inhibitory polypeptide.
|
Lancet
|
1972
|
1.44
|
|
27
|
Neuron specific enolase: a common marker for the endocrine cells and innervation of the gut and pancreas.
|
Gastroenterology
|
1982
|
1.41
|
|
28
|
Immunohistochemical localisation of urogastrone to human duodenal and submandibular glands.
|
Gut
|
1978
|
1.41
|
|
29
|
Immunofluorescent localization of enteroglucagon cells in the gastrointestinal tract of the dog.
|
Gut
|
1971
|
1.37
|
|
30
|
The cytochemistry of the thyroid C cells and their relationship to calcitonin.
|
Proc R Soc Lond B Biol Sci
|
1966
|
1.37
|
|
31
|
The newer gut hormones. Cellular sources, physiology, pathology, and clinical aspects.
|
Gastroenterology
|
1977
|
1.36
|
|
32
|
Neural crest origin of the endocrine polypeptide (APUD) cells of the gastrointestinal tract and pancreas.
|
Gut
|
1971
|
1.33
|
|
33
|
Cytochemical, immunofluorescence and ultrastructural investigations on the antral G cells in hyperparathyroidism.
|
Virchows Arch B Cell Pathol
|
1971
|
1.33
|
|
34
|
Embryology of the diffuse neuroendocrine system and its relationship to the common peptides.
|
Fed Proc
|
1979
|
1.32
|
|
35
|
Secretin cells in coeliac disease.
|
Gut
|
1973
|
1.31
|
|
36
|
Immunofluorescent localization of calcitonin in the 'C' cells of pig and dog thyroid.
|
J Endocrinol
|
1967
|
1.29
|
|
37
|
Zollinger-Ellison syndrome type 1: clinical and pathological correlations in a case.
|
Gut
|
1973
|
1.27
|
|
38
|
5-hydroxytryptophan uptake by dog thyroid 'C' cells, and its possible significance in polypeptide hormone production.
|
Nature
|
1966
|
1.25
|
|
39
|
Cellular localization of a vasoactive intestinal peptide in the mammalian and avian gastrointestinal tract.
|
Gut
|
1974
|
1.24
|
|
40
|
Complete identification of endocrine cells in the gastrointestinal tract using semithin-thin sections to identify motilin cells in human and animal intestine.
|
Gut
|
1975
|
1.23
|
|
41
|
Diffuse lipofuscinosis of the central nervous system.
|
Neurology
|
1967
|
1.23
|
|
42
|
Enterochromaffin cells of the mammalian small intestine as the source of motilin.
|
Virchows Arch B Cell Pathol
|
1974
|
1.22
|
|
43
|
Cytochemical evidence for an ultimobranchial origin of rodent thyroid C cells.
|
Nature
|
1967
|
1.22
|
|
44
|
Electronimmunocytochemical evidence for the K cell localization of gastric inhibitory polypeptide (GIP) in man.
|
Histochemistry
|
1978
|
1.20
|
|
45
|
Distribution of a bombesin-like peptide in human gastrointestinal tract.
|
Lancet
|
1976
|
1.20
|
|
46
|
Identification of the intestinal cell storing gastric inhibitory peptide.
|
Histochemistry
|
1975
|
1.19
|
|
47
|
Common cytochemical properties of cells producing polypeptide hormones, with particular reference to calcitonin and the thyroid C cells.
|
Vet Rec
|
1966
|
1.19
|
|
48
|
Substance P-like immunoreactive nerves in mammalian lung.
|
Invest Cell Pathol
|
1980
|
1.17
|
|
49
|
Enkephalin-, VIP- and substance P-like immunoreactivity in the carotid body.
|
Nature
|
1980
|
1.15
|
|
50
|
The G cells in pernicious anaemia.
|
Gut
|
1971
|
1.13
|
|
51
|
Identification of cholecystokinin-secreting cells.
|
Lancet
|
1975
|
1.13
|
|
52
|
Cytochemical evidence for the neural crest origin of mammalian ultimobranchial C cells.
|
Histochemie
|
1971
|
1.12
|
|
53
|
Demonstration of the neural crest origin of type I (APUD) cells in the avian carotid body, using a cytochemical marker system.
|
Histochemie
|
1973
|
1.08
|
|
54
|
Diethylpyrocarbonate, a vapour-phase fixative for immunofluorescence studies on polypeptide hormones.
|
Histochem J
|
1974
|
1.08
|
|
55
|
Cellular localization of gastric inhibitory polypeptide in the duodenum and jejunum.
|
Gut
|
1973
|
1.07
|
|
56
|
Serum gastrin levels in malignant Zollinger-Ellison Syndrome after total gastrectomy and hypophysectomy.
|
Ann Surg
|
1970
|
1.06
|
|
57
|
Immunofluorescent localization of secretin and enteroglucagon in human intestinal mucosa.
|
Scand J Gastroenterol
|
1971
|
1.04
|
|
58
|
Cytochemical and ultrastructural observations on the argentaffin and argyrophil cells of the gastro-intestinal tract in mammals, and their place in the APUD series of polypeptide-secreting cells.
|
Histochemie
|
1968
|
1.04
|
|
59
|
Fluorogenic amine tracing of neural crest derivatives forming the adrenal medulla.
|
Gen Comp Endocrinol
|
1971
|
1.04
|
|
60
|
Neuroendocrine embryology and the APUD concept.
|
Clin Endocrinol (Oxf)
|
1976
|
1.04
|
|
61
|
Percutaneous needle biopsy in the diagnosis of muscle diseases.
|
Lancet
|
1973
|
1.04
|
|
62
|
Histochemical study on the Paneth cell in the rat.
|
Gut
|
1966
|
1.03
|
|
63
|
Quantification of secretion release by acid, using immunocytochemistry and radioimmunoassay.
|
Experientia
|
1975
|
1.02
|
|
64
|
The effect of catecholamines on alkaline phosphatase activity in rat heart.
|
Cardiovasc Res
|
1969
|
1.02
|
|
65
|
The identification of gastrin cells as G cells.
|
Virchows Arch A Pathol Pathol Anat
|
1972
|
1.02
|
|
66
|
The melanocyte: its cytochemical and immunological relationship to cells of the endocrine polypeptide (APUD) series.
|
Virchows Arch B Cell Pathol
|
1969
|
1.01
|
|
67
|
Qualitative and quantitative studies of antral and fundic G cells in pernicious anaemia.
|
Scand J Gastroenterol
|
1973
|
0.98
|
|
68
|
Electron immunohistochemical evidence for the human intestinal I cell as the source of CCK.
|
Gut
|
1978
|
0.98
|
|
69
|
Non-G cell gastrin-producing tumours of the pancreas.
|
Virchows Arch B Cell Pathol
|
1972
|
0.98
|
|
70
|
Immunocytochemical confirmation of the neural crest origin of avian calcitonin-producing cells.
|
Histochemistry
|
1974
|
0.97
|
|
71
|
Substance P: a naturally occurring transmitter in human spinal cord.
|
Lancet
|
1976
|
0.97
|
|
72
|
Vasoactive intestinal polypeptide (VIP)-like immunoreactivity in salivary glands.
|
Life Sci
|
1979
|
0.97
|
|
73
|
Endocrine tumours of neural crest origin: neurolophomas, apudomas and the APUD concept.
|
Med Biol
|
1974
|
0.96
|
|
74
|
Single cellular origin of somatostatin and calcitonin in the rat thyroid gland.
|
Histochemistry
|
1977
|
0.96
|
|
75
|
Histology and cytochemistry of the cells of the small intestine, in relation to absorption.
|
Br Med Bull
|
1967
|
0.95
|
|
76
|
Enterochromaffin cells as the endocrine source of gastrointestinal substance P.
|
Histochemistry
|
1976
|
0.95
|
|
77
|
Preservation of tissue mucins by freeze-drying and vapour fixation. I. Light microscopy.
|
J R Microsc Soc
|
1965
|
0.95
|
|
78
|
The APUD concept and hormone production.
|
Clin Endocrinol Metab
|
1980
|
0.95
|
|
79
|
G cell population of the gastric antrum, plasma gastrin, and gastric acid secretion in patients with and without duodenal ulcer.
|
Gut
|
1978
|
0.94
|
|
80
|
The demonstration of dehydrogenases and monoamine oxidase by the formation of osmium blacks at the sites of Hatchett's brown.
|
Histochemie
|
1973
|
0.94
|
|
81
|
"Myopathy" with tubular aggregates.
|
J Neurol Sci
|
1971
|
0.93
|
|
82
|
Neuron-specific enolase as an immunocytochemical marker for the diffuse neuroendocrine system in human fetal lung.
|
J Histochem Cytochem
|
1981
|
0.93
|
|
83
|
Ultrastructural localization of calcitonin in C-cells of dog thyroid; an immunocytochemical study.
|
Histochemie
|
1971
|
0.92
|
|
84
|
Differential localisation of substance P and motilin.
|
Scand J Gastroenterol Suppl
|
1976
|
0.92
|
|
85
|
Neuron-specific enolase in the Merkel cells of mammalian skin. The use of specific antibody as a simple and reliable histologic marker.
|
Am J Pathol
|
1981
|
0.89
|
|
86
|
Fluorescence metachromasia in polypeptide hormone-producing cells of the APUD series, and its significance in relation to the structure of the precursor protein.
|
Histochem J
|
1969
|
0.89
|
|
87
|
The neuroendocrine (APUD) cells of the skin.
|
Am J Dermatopathol
|
1980
|
0.88
|
|
88
|
Carbodiimide fixation for immunohistochemistry: observations on the fixation of polypeptide hormones.
|
Experientia
|
1971
|
0.88
|
|
89
|
The APUD cells of the alimentary tract in health and disease.
|
Med Clin North Am
|
1974
|
0.87
|
|
90
|
Uptake of L-dopa and L-5-hydroxytryptophan by endocrine-like cells in the rat larynx.
|
Histochem J
|
1972
|
0.87
|
|
91
|
Intestinal mucosal hyperplasia following induced hyperthyroidism in the rat.
|
Virchows Arch B Cell Pathol
|
1970
|
0.87
|
|
92
|
A microspectrofluorimeter with epi-illumination and photon counting.
|
J Microsc
|
1969
|
0.87
|
|
93
|
Immunoelectron cytochemical localization of motilin in human duodenal enterochromaffin cells.
|
Gastroenterology
|
1978
|
0.86
|
|
94
|
Peptide hormone-like immunoreactivity in the gastrointestinal tract and endocrine pancreas of eleven teleost species.
|
Cell Tissue Res
|
1979
|
0.86
|
|
95
|
Cellular origin of human pancreatic polypeptide (HPP) in endocrine tumours of the pancreas.
|
Virchows Arch B Cell Pathol
|
1976
|
0.86
|
|
96
|
Cytochemical and ultrastructural differentiation of enteroglucagon and pancreatic-type glucagon cells of the gastrointestinal tract.
|
Virchows Arch B Cell Pathol
|
1976
|
0.86
|
|
97
|
The electron cytochemistry of ubiguinone in mammalian heart, demonstrated with a momotetrazolium salt.
|
Histochemie
|
1965
|
0.85
|
|
98
|
Genetic aspects of the Z-E syndrome: prospective studies in two kindred; antral gastrin cell hyperplasia.
|
Ann Surg
|
1972
|
0.85
|
|
99
|
Specific immunostaining of CCK cells by use of synthetic fragment antisera.
|
Experientia
|
1977
|
0.85
|
|
100
|
Polypeptide hormone production by "carcinoid" apudomas and their relevant cytochemistry.
|
Virchows Arch B Cell Pathol
|
1974
|
0.84
|
|
101
|
Neurocristopathy, neuroendocrine pathology and the APUD concept.
|
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol
|
1975
|
0.84
|
|
102
|
The diffuse neuroendocrine system: peptides, amines, placodes and the APUD theory.
|
Prog Brain Res
|
1986
|
0.84
|
|
103
|
Mouse epidermal growth factor: light and electron microscopical localisation by immunocytochemical staining.
|
Histochemistry
|
1977
|
0.84
|
|
104
|
Ultrastructural characteristics of the thyroid C cells in the summer, autumn and winter states of the hedgehog (Erinaceus europaeus L.), with some reference to other mammalian species.
|
Z Zellforsch Mikrosk Anat
|
1968
|
0.84
|
|
105
|
The cells of Cajal-Retzius in the developing human brain.
|
J Anat
|
1968
|
0.84
|
|
106
|
Histoenzymatic study of fetal medulloblastoma with associated congenital malformations.
|
Neurology
|
1966
|
0.84
|
|
107
|
Differentiation of fibre types in normal and dystrophic hamster muscle.
|
J Neurol Sci
|
1971
|
0.84
|
|
108
|
The histochemical demonstration of five lysosomal enzymes in the pars distalis of the amphibian pituitary.
|
Z Zellforsch Mikrosk Anat
|
1966
|
0.83
|
|
109
|
Immunostaining of neuron-specific enolase as a diagnostic tool for Merkel cell tumors.
|
Cancer
|
1983
|
0.83
|
|
110
|
Antral G-cell hyperplasia with hypergastrinaemia producing a Zollinger-Ellison syndrome.
|
Gut
|
1972
|
0.83
|
|
111
|
Immunoelectron cytochemical localization of motilin and substance P in rabbit bile duct enterochromaffin (EC) cells.
|
Histochemistry
|
1977
|
0.83
|
|
112
|
Histochemical changes in the rat small intestine associated with enhanced absorption after high bulk feeding.
|
Enzymol Biol Clin (Basel)
|
1965
|
0.83
|
|
113
|
Development, differentiation and derivation of the endocrine polypeptide cells of the mouse pancreas. Immunofluorescence, cytochemical and ultrastructural studies.
|
Diabetologia
|
1973
|
0.82
|
|
114
|
Identification of the D1-cell as the source of human pancreatic polypeptide (HPP).
|
Gut
|
1976
|
0.82
|
|
115
|
Anti-gastrin immunofluorescence in the skin of Hyla crepitans and the cytochemistry of the cells involved.
|
Experientia
|
1970
|
0.81
|
|
116
|
The G cell population of the pyloric antrum of the cat.
|
Digestion
|
1975
|
0.81
|
|
117
|
Proceedings: Pancreatic D cells in normal and pathological human pancreas.
|
Gut
|
1975
|
0.81
|
|
118
|
Islet cell precursors are neurones.
|
Nature
|
1982
|
0.81
|
|
119
|
Electron microscopy of paraffin-embedded material in amyloidosis.
|
J Pathol Bacteriol
|
1966
|
0.81
|
|
120
|
Random coil conformation of polypeptide hormone precursor protein in endocrine cells.
|
Nature
|
1969
|
0.81
|
|
121
|
Demonstration of acid phosphatase activity in the Golgi apparatus of the jejunal epithelium cell in patients with idiopathic steatorrhea.
|
Histochemie
|
1965
|
0.81
|
|
122
|
Ultrastructural localization of alkaline phosphatase in rat atrium.
|
J Mol Cell Cardiol
|
1971
|
0.80
|
|
123
|
Gut hormones in Salamandra salamandra. An immunocytochemical and electron microscopic investigation.
|
Cell Tissue Res
|
1980
|
0.80
|
|
124
|
Immunoreactive polypeptide hormones in the pancreas and gut of the lamprey.
|
Gen Comp Endocrinol
|
1974
|
0.80
|
|
125
|
The inducible alkaline phosphatase of rat heart. Some properties of the enzyme and factors influencing its activity.
|
Biochem J
|
1971
|
0.80
|
|
126
|
Carbodiimide fixation for electron microscopy and immunoelectron cytochemistry.
|
Experientia
|
1972
|
0.80
|
|
127
|
The diffuse endocrine system and the implications of the APUD concept.
|
Int Surg
|
1979
|
0.80
|
|
128
|
Ultrastructural localization of succinate dehydrogenase in mouse liver mitochondria; a cytochemical study.
|
J Histochem Cytochem
|
1971
|
0.80
|
|
129
|
Gastro-intestinal and neurohormonal peptides in the alimentary tract and cerebral complex of Ciona intestinalis (Ascidiaceae).
|
Cell Tissue Res
|
1982
|
0.79
|
|
130
|
The cellular origin of motilin in the gastrointestinal tract.
|
Scand J Gastroenterol Suppl
|
1976
|
0.79
|
|
131
|
Localisation of intestinal gastrin in a distinct endocrine cell type.
|
Nature
|
1979
|
0.79
|
|
132
|
Neuroectodermal origin of avian hypothalamo-hypophyseal complex: the role of the ventral neural ridge.
|
J Embryol Exp Morphol
|
1975
|
0.79
|
|
133
|
Neuron-specific enolase in the pituitary gland.
|
Neuroendocrinology
|
1984
|
0.79
|
|
134
|
Familial pheochromocytoma and islet cell tumor of the pancreas.
|
Am J Med
|
1980
|
0.79
|
|
135
|
Gastrointestinal apudosis in obese hyperglycaemic mice.
|
Virchows Arch B Cell Pathol
|
1975
|
0.79
|
|
136
|
Immunocytochemical demonstration of 5-hydroxytryptamine in gastrointestinal endocrine cells.
|
Histochem J
|
1979
|
0.79
|
|
137
|
Immunofluorescent localisation of calcitonin in medullary C-cell thyroid carcinoma, using antibody to the pure porcine hormone.
|
Virchows Arch B Cell Pathol
|
1969
|
0.79
|
|
138
|
Cytochemical and immunofluorescence investigations of insulin-like producing cells in the intestine of Mytilus edulis L. (Bivalvia).
|
Cell Tissue Res
|
1976
|
0.78
|
|
139
|
Cytochemical localization of redox compounds in isolated bovine retinal outer segment disks.
|
Nature
|
1966
|
0.78
|
|
140
|
A new universal technique for the immunocytochemical localization of peptidergic innervation [proceedings].
|
J Endocrinol
|
1978
|
0.78
|
|
141
|
Localization of somatostatin-, substance P- and calcitonin-like immunoreactivity in the neural ganglion of Ciona intestinalis L. (Ascidiaceae).
|
Cell Tissue Res
|
1979
|
0.78
|
|
142
|
Calcitonin-like immunochemical staining in the alimentary tract of Ciona intestinalis L.
|
Cell Tissue Res
|
1980
|
0.78
|
|
143
|
Functional and analytical histochemistry of the chicken lung lobule with particular reference to surfactant.
|
Poult Sci
|
1966
|
0.78
|
|
144
|
The calcitonin secreting C cells and their relationship to the APUD cell series.
|
J Endocrinol
|
1969
|
0.78
|
|
145
|
Localisation of somatostatin- and gastrin-like immunoreactivity in the gastrointestinal tract of Ciona intestinalis L.
|
Cell Tissue Res
|
1978
|
0.78
|
|
146
|
Electron cytochemistry of BuChE and AChE in thyroid and parathyroid C cells, under normal and experimental conditions.
|
Histochemie
|
1969
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Cytochemical and immunofluorescence investigations on polypeptide hormone localization in the pancreas and gut of the larval lamprey.
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On the origin of islet parencymal cells in a cyclostome, Myxine glutinosa. A fluorescence microscopical and ultrastructural study with particular reference to endocrine cells in the bile duct mucosa.
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The nature of the solitary active cells of the central nervous system.
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Cytochemical identification of human and murine pituitary corticotrophs and somatotrophs as APUD cells.
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Fine structural localization of succinoxidase complex on the mitochondrial cristae.
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The neural crest origin of gastrointestinal and panceatic endocrine polypeptide cells and their distinction by sequential immunofluorescence.
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Immunohistochemical and ultrastructural studies on the endocrine polypeptide (APUD) cells of the avian gastrointestinal tract.
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The presence of bombesin, a recently discovered gut and brain peptide, in human lung [proceedings].
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