Published in N Engl J Med on June 21, 1973
Changes in occurrence of capsular serotypes of Streptococcus pneumoniae at Boston City Hospital during selected years between 1935 and 1974. J Clin Microbiol (1977) 3.37
Updated review of blood culture contamination. Clin Microbiol Rev (2006) 3.16
Pneumococcal bacteraemia: 325 episodes diagnosed at St Thomas's Hospital. Br Med J (Clin Res Ed) (1985) 1.98
Haemophilus influenzae bacteremia and meningitis resulting from survival of a single organism. Proc Natl Acad Sci U S A (1978) 1.88
Oral immunization with PspA elicits protective humoral immunity against Streptococcus pneumoniae infection. Infect Immun (1997) 1.24
Recovery of Haemophilus influenzae from twenty-three blood culture media. J Clin Microbiol (1979) 1.21
Changing epidemiology of serious bacterial infections in febrile infants without localizing signs. PLoS One (2010) 1.02
Occult pneumococcal bacteraemia and febrile convulsions. Br Med J (Clin Res Ed) (1983) 0.91
Limb infections in infancy presenting with pseudoparalysis. Arch Dis Child (1975) 0.85
Effects of obtaining a blood culture on subsequent management of young febrile children without an evident focus of infection. CMAJ (1986) 0.83
Utility of blood culture in uncomplicated pneumonia in children. Clin Med Insights Pediatr (2013) 0.80
Evaluation of a protocol for selective empiric treatment of fever without localising signs. Arch Dis Child (1997) 0.80
Cold comfort for hot children. Br Med J (Clin Res Ed) (1983) 0.80
Evaluation of the precision of emergency department diagnoses in young children with fever. Clin Pediatr (Phila) (2011) 0.79
Unexplained fever in young children: how to manage severe bacterial infection. BMJ (2003) 0.78
Occult bacteremia with nontypeable Haemophilus influenzae. J Clin Microbiol (1987) 0.77
Diagnostic workup of febrile children under 24 months of age: a clinical review. West J Med (1982) 0.76
Infectious diseases: annual review of significant publications. Postgrad Med J (1974) 0.75
Should lumbar puncture be routinely performed in patients with suspected bacteremia? J Natl Med Assoc (1983) 0.75
Pattern of febrile illnesses in children seen at a pediatric ambulatory care setting. J Family Community Med (2000) 0.75
Approach to the febrile child: A challenge bridging the gap between the literature and clinical practice. Paediatr Child Health (2003) 0.75
Occult pneumococcal bacteraemia and febrile convulsions. Br Med J (Clin Res Ed) (1983) 0.75
ANTIBODY RESPONSE TO INFECTIONS WITH THE NEWLY CLASSIFIED TYPES OF PNEUMOCOCCI (COOPER). J Clin Invest (1934) 10.11
Susceptibility of group D streptococcus (enterococcus) to 21 antibiotics in vitro, with special reference to species differences. Am J Med Sci (1969) 10.08
STUDIES ON THE ACTION OF SULFAPYRIDINE ON PNEUMOCOCCI. J Clin Invest (1940) 9.39
COLD AGGLUTININS (AUTOHEMAGGLUTININS) IN PRIMARY ATYPICAL PNEUMONIAS. Science (1943) 9.20
Rapid microassay of gentamicin, kanamycin, neomycin, streptomycin, and vancomycin in serum or plasma. J Lab Clin Med (1971) 8.13
OBSERVATIONS ON THE INHIBITION OF SULFONAMIDE ACTION BY PARA-AMINOBENZOIC ACID. J Clin Invest (1941) 8.03
Changing ecology of bacterial infections as related to antibacterial therapy. J Infect Dis (1970) 7.72
Observations on Bacteria Sensitive to, Resistant to, and Dependent upon Streptomycin. J Bacteriol (1948) 7.56
Effect of inoculum and of beta-lactamase on the anti-staphylococcal activity of thirteen penicillins and cephalosporins. Antimicrob Agents Chemother (1975) 6.82
Bacteriologic Studies on Aureomycin. J Bacteriol (1948) 5.91
Ampicillin-resistant Haemophilus influenzae type B infection. JAMA (1974) 5.90
Epidemiology of otitis media during the first seven years of life in children in greater Boston: a prospective, cohort study. J Infect Dis (1989) 5.87
A COMPARATIVE STUDY OF THE BLOOD CONCENTRATIONS AND URINARY EXCRETION OF SULFAPYRIDINE AND SULFANILAMIDE AFTER SINGLE DOSES OF SULFAPYRIDINE AND RELATED COMPOUNDS ADMINISTERED BY VARIOUS ROUTES. J Clin Invest (1940) 5.45
BACTERICIDAL ACTION OF SODIUM SULFAPYRIDINE AND OF A GLUCOSE-SULFAPYRIDINE SOLUTION IN HUMAN BLOOD. J Clin Invest (1940) 4.89
Antimicrobial resistance in hospital organisms and its relation to antibiotic use. Rev Infect Dis (1984) 4.42
THE INFLUENCE OF DOSAGE AND ROUTE OF INJECTION ON THE ANTIBODY RESPONSE OF HUMAN SUBJECTS TO THE SPECIFIC CARBOHYDRATE OF THE TYPE VIII PNEUMOCOCCUS. J Clin Invest (1935) 4.41
Methicillin-resistant Staphylococcus aureus at Boston City Hospital. Bacteriologic and epidemiologic observations. N Engl J Med (1968) 4.38
Microassay for human and chick cell interferons. Appl Microbiol (1968) 4.20
Direct detection of Mycobacterium tuberculosis in sputum by polymerase chain reaction and DNA hybridization. J Clin Microbiol (1993) 4.13
Susceptibility of common pathogenic bacteria to seven tetracycline antibiotics in vitro. Am J Med Sci (1968) 4.00
Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin. Am J Med Sci (1968) 3.78
Surveillance of antimicrobial use and antimicrobial resistance in United States hospitals: project ICARE phase 2. Project Intensive Care Antimicrobial Resistance Epidemiology (ICARE) hospitals. Clin Infect Dis (1999) 3.77
Practice guideline for the management of infants and children 0 to 36 months of age with fever without source. Agency for Health Care Policy and Research. Ann Emerg Med (1993) 3.67
Susceptibility of Staphylococcus aureus and Staphylococcus epidermidis to 65 antibiotics. Antimicrob Agents Chemother (1976) 3.59
Haemophilus influenzae infections in adults: characterization of strains by serotypes, biotypes, and beta-lactamase production. J Infect Dis (1981) 3.45
Projected cost-effectiveness of pneumococcal conjugate vaccination of healthy infants and young children. JAMA (2000) 3.42
Changes in occurrence of capsular serotypes of Streptococcus pneumoniae at Boston City Hospital during selected years between 1935 and 1974. J Clin Microbiol (1977) 3.37
Society for Healthcare Epidemiology of America and Infectious Diseases Society of America Joint Committee on the Prevention of Antimicrobial Resistance: guidelines for the prevention of antimicrobial resistance in hospitals. Clin Infect Dis (1997) 3.29
Pathology of Staphylococcal Pneumonia Complicating Clinical Influenza. Am J Pathol (1943) 3.28
Antibacterial action of "broad-spectrum" penicillins, cephalosporins and other antibiotics against Gram-negative bacilli isolated from bacteremic patients. Ann N Y Acad Sci (1967) 3.17
PNEUMOCOCCIC INFECTIONS IN FAMILIES. J Clin Invest (1936) 3.14
The Klebsiella-Enterobacter-Serratia division. Biochemical and serologic characteristics and susceptibility to antibiotics. Ann Intern Med (1966) 3.07
Characterization of clinical isolates of Klebsiella pneumoniae from 19 laboratories using the National Committee for Clinical Laboratory Standards extended-spectrum beta-lactamase detection methods. J Clin Microbiol (2001) 3.06
Susceptibility of Nocardia asteroides to 45 antimicrobial agents in vitro. Antimicrob Agents Chemother (1973) 3.05
Antimicrobial resistance in isolates from inpatients and outpatients in the United States: increasing importance of the intensive care unit. Clin Infect Dis (1997) 2.98
The Klebsiella-Enterobacter-Serratia division. Clinical and epidemiologic characteristics. Ann Intern Med (1966) 2.92
Pathologic Findings in the Lungs of Five Cases from Which Influenza Virus Was Isolated. Am J Pathol (1946) 2.91
Serratia marcescens: biochemical, serological, and epidemiological characteristics and antibiotic susceptibility of strains isolated at Boston City Hospital. Appl Microbiol (1970) 2.83
Bacterial colonization and clinical superinfection of the respiratory tract complicating antibiotic treatment of pneumonia. J Infect Dis (1969) 2.80
Bacteremia at Boston City Hospital: Occurrence and mortality during 12 selected years (1935-1972), with special reference to hospital-acquired cases. J Infect Dis (1975) 2.78
The epidemiology of pneumococcal disease in infants and children. Rev Infect Dis (1981) 2.76
Rapid microassay for circulating nephrotoxic antibiotics. Antimicrob Agents Chemother (Bethesda) (1970) 2.73
Report of the Task Force on Diagnosis and Management of Meningitis. Pediatrics (1986) 2.62
Enhancing effect on alkalinization of the medium on the activity of erythromycin against gram-negative bacteria. Appl Microbiol (1968) 2.55
Synergistic combinations of penicillins in the treatment of bacteriuria. N Engl J Med (1967) 2.53
Clinical utility of blood cultures in adult patients with community-acquired pneumonia without defined underlying risks. Chest (1995) 2.49
Microbiology of otitis media. Ann Otol Rhinol Laryngol Suppl (1981) 2.46
Excretion of erythromycin and its enhanced activity in urine against gram-negative bacilli with alkalinization. J Lab Clin Med (1968) 2.45
OBSERVATIONS ON THE URINARY EXCRETION OF SULFADIAZINE. J Clin Invest (1943) 2.44
Use of gentamicin in combinations with other antibiotics. J Infect Dis (1969) 2.37
Streptomycin-sensitive, -dependent, and -resistant Bacteria. Science (1948) 2.23
AGGLUTININS FOR HUMAN ERYTHROCYTES IN TYPE XIV ANTI-PNEUMOCOCCIC HORSE SERUMS. Science (1938) 2.23
The genital mycoplasmas. N Engl J Med (1973) 2.21
Susceptibility of pneumococci to nine antibiotics. Am J Med Sci (1965) 2.19
Parents, physicians, and antibiotic use. Pediatrics (1999) 2.18
Otitis media in infancy and intellectual ability, school achievement, speech, and language at age 7 years. Greater Boston Otitis Media Study Group. J Infect Dis (1990) 2.14
Susceptibility of genital mycoplasmas to antimicrobial agents. Appl Microbiol (1970) 2.13
Antibiotic susceptibility of gram-negative bacilli isolated from blood cultures. Results of tests with 35 agents and strains from 169 patients at Boston City Hospital during 1972. Am J Med (1974) 2.13
Infections and antibiotic use among patients at Boston City Hospital, February, 1967. N Engl J Med (1968) 2.12
Cephaloridine activity in vitro and absorption and urinary excretion in normal young men. Am J Med Sci (1966) 2.09
Thiol-group binding of zinc to a beta-lactamase of Bacillus cereus: differential effects on enzyme activity with penicillin and cephalosporins as substrates. J Bacteriol (1968) 2.08
Carbenicillin: activity in vitro and absorption and excretion in normal young men. Appl Microbiol (1968) 2.07
Changing etiology of bacterial endocarditis in the antibacterial era. Experiences at Boston City Hospital 1933-1965. Ann Intern Med (1970) 2.06
Detection of positive blood cultures by the Bactec NR660. The clinical importance of five versus seven days of testing. Am J Clin Pathol (1988) 2.04
Isolation of viruses and mycoplasmas from middle ear effusions: a review. Ann Otol Rhinol Laryngol (1976) 2.04
THE NEW PENICILINS. N Engl J Med (1963) 2.02
Methodologic investigations and prevalence of genital mycoplasmas in pregnancy. J Infect Dis (1970) 2.02
Lincomycin: activity in vitro and absorption and excretion in normal young men. Am J Med Sci (1967) 2.00
Colonization of newborn infants by mycoplasmas. N Engl J Med (1969) 1.98
Pulmonary nocardiosis. Therapy with minocycline and with erythromycin plus ampicillin. JAMA (1973) 1.94
Activity of minocycline against Nocardia asteroides: comparison with tetracycline in agar-dilution and standard disc-diffusion tests and with sulfadiazine in an experimental infection of mice. J Lab Clin Med (1973) 1.90
Resistance of penicillins and cephalosporins to beta-lactamases from Gram-negative bacilli: some correlations with antibacterial activity. Ann N Y Acad Sci (1967) 1.88
Acute otitis media in children. Serologic studies and attempts to isolate viruses and mycoplasmas from aspirated middle-ear fluids. N Engl J Med (1967) 1.87
Determinants of vancomycin use in adult intensive care units in 41 United States hospitals. Clin Infect Dis (1999) 1.86
Evaluation of new anti-infective drugs for the treatment of respiratory tract infections. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis (1992) 1.86
Usage of antibiotics in a general hospital: effect of requiring justification. J Infect Dis (1974) 1.86
Infection and antibiotic usage at Boston City Hospital: changes in prevalence during the decade 1964-1973. J Infect Dis (1974) 1.83
Changing patterns of susceptibility of common bacterial pathogens to antimicrobial agents. Ann Intern Med (1972) 1.83
Society for Healthcare Epidemiology of America and Infectious Diseases Society of America Joint Committee on the Prevention of Antimicrobial Resistance: guidelines for the prevention of antimicrobial resistance in hospitals. Infect Control Hosp Epidemiol (1997) 1.82
Effect of pH of medium and size of inoculum on activity of antibiotics against group D Streptococcus (Enterococcus). Appl Microbiol (1970) 1.78
Epidemiology of otitis media in children. Ann Otol Rhinol Laryngol Suppl (1981) 1.77
Therapeutic and epidemiologic recommendations to reduce the spread of type-I beta-lactamase resistance. Diagn Microbiol Infect Dis (1992) 1.74
Reovirus-like agent as a cause of nosocomial diarrhea in infants. J Pediatr (1977) 1.73
Reasons for the emergence of antibiotic resistance. Am J Med Sci (1996) 1.73
Absorption and excretion of five tetracycline analogues in normal young men. Am J Med Sci (1968) 1.72
The effect of vancomycin and third-generation cephalosporins on prevalence of vancomycin-resistant enterococci in 126 U.S. adult intensive care units. Ann Intern Med (2001) 1.72
Rainfall, household crowding, and acute respiratory infections in the tropics. Epidemiol Infect (2011) 1.71
Pneumococcal bacteremia. Review of 111 cases, 1957--1969, with special reference to cases with undetermined focus. Am J Dis Child (1971) 1.71
Purpose of quality standards for infectious diseases. Infectious Diseases Society of America. Clin Infect Dis (1994) 1.70
Glycopeptide-intermediate Staphylococcus aureus: evaluation of a novel screening method and results of a survey of selected U.S. hospitals. J Clin Microbiol (1999) 1.68
Extra charges and prolongation of stay attributable to nosocomial infections: a prospective interhospital comparison. Am J Med (1981) 1.65
Susceptibility of beta-hemolytic streptococci to 65 antibacterial agents. Antimicrob Agents Chemother (1976) 1.65