Pathologic findings in a case of cardiac transplantation.

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🔗 View Article (PMID 4175711)

Published in JAMA on October 21, 1968

Authors

A M Saunders, C Bieber

Articles by these authors

(truncated to the top 100)

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science (1993) 33.32

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A (1993) 15.04

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat Genet (1994) 7.07

Patterns of brain activation in people at risk for Alzheimer's disease. N Engl J Med (2000) 6.72

Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype. Arch Neurol (1998) 5.93

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc Natl Acad Sci U S A (1993) 5.68

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proc Natl Acad Sci U S A (1993) 4.86

Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proc Natl Acad Sci U S A (2000) 4.85

Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12. JAMA (1997) 4.00

Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease. Pharmacogenomics J (2006) 3.92

Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein E and Alzheimer's Disease. N Engl J Med (1998) 3.23

Neuropathological and neuropsychological changes in "normal" aging: evidence for preclinical Alzheimer disease in cognitively normal individuals. J Neuropathol Exp Neurol (1998) 2.92

A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease. Pharmacogenomics J (2009) 2.66

ApoE genotype and survival from intracerebral haemorrhage. Lancet (1995) 2.07

An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease. Nat Genet (1999) 2.01

Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype. Exp Neurol (1994) 1.84

Identification of novel genes in late-onset Alzheimer's disease. Exp Gerontol (2000) 1.74

Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. Proc Natl Acad Sci U S A (1994) 1.74

Clinical application of apolipoprotein E genotyping to Alzheimer's disease. Lancet (1994) 1.71

Flow cytometric analysis of lymphocyte phenotypes in AIDS using monoclonal antibodies and simultaneous dual immunofluorescence. Clin Immunol Immunopathol (1986) 1.68

Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs. Neurobiol Aging (1996) 1.65

Apolipoprotein E4 allele frequency, ischemic cerebrovascular disease, and Alzheimer's disease. Stroke (1993) 1.63

There is a pathologic relationship between ApoE-epsilon 4 and Alzheimer's disease. Arch Neurol (1995) 1.51

Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center. Ann Thorac Surg (1997) 1.48

Apolipoprotein E epsilon 4 allele and hippocampal volume in twins with normal cognition. Neurology (1997) 1.47

No genetic effect of alpha1-antichymotrypsin in Alzheimer disease. Genomics (1996) 1.45

Smoking, Alzheimer's disease, and confounding with genes. Lancet (1995) 1.43

Apolipoprotein E in Creutzfeldt-Jacob disease. Lancet (1995) 1.41

ApoE, Alzheimer's disease, and recovery from brain stress. Ann N Y Acad Sci (1997) 1.40

Analysis of association at single nucleotide polymorphisms in the APOE region. Genomics (2000) 1.40

A twin study of late-onset depression and apolipoprotein E epsilon 4 as risk factors for Alzheimer's disease. Biol Psychiatry (1997) 1.39

Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. Neurobiol Dis (1996) 1.35

APOE is a major susceptibility gene for Alzheimer's disease. Curr Opin Biotechnol (1994) 1.33

The Hemalog D white cell differential system. J Histochem Cytochem (1974) 1.32

Association of the apolipoprotein E gene with age-related macular degeneration: possible effect modification by family history, age, and gender. Mol Vis (2000) 1.31

Alzheimer's disease in the National Academy of Sciences-National Research Council Registry of Aging Twin Veterans. III. Detection of cases, longitudinal results, and observations on twin concordance. Arch Neurol (1995) 1.27

Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity. Am J Hum Genet (2000) 1.26

Apolipoprotein E-epsilon 2 and Alzheimer's disease: genotype influences pathologic phenotype. Neurology (1997) 1.24

Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study. J Neuropathol Exp Neurol (1994) 1.22

Divergent effects of bryostatin 1 and phorbol myristate acetate on cell cycle arrest and maturation in human myelomonocytic leukemia cells (U937). Differentiation (1998) 1.22

High survival in poor years: life history tactics adapted to mast seeding in the edible dormouse. Ecology (2006) 1.17

Transplantation tolerance after total lymphoid irradiation. Transplant Proc (1979) 1.15

Using genetics to enable studies on the prevention of Alzheimer's disease. Clin Pharmacol Ther (2012) 1.14

Intracerebral hemorrhage outcome: apolipoprotein E genotype, hematoma, and edema volumes. Neurology (1999) 1.13

Sequestration of amyloid beta-peptide. Ann N Y Acad Sci (1993) 1.13

Corticosteroids in the treatment of Engelmann's disease: progressive diaphyseal dysplasia. Pediatrics (1970) 1.11

Memory self-appraisal in middle-aged and older adults with the apolipoprotein E-4 allele. Am J Psychiatry (1999) 1.11

Familial and sporadic Alzheimer's disease: neuropathology cannot exclude a final common pathway. Neurology (1996) 1.10

Characterization of murine carcinoembryonic antigen gene family members. Mamm Genome (1992) 1.09

Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls. Exp Neurol (1994) 1.09

Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease. Neurology (1995) 1.08

Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease). Pharmacogenomics J (2006) 1.08

Heart graft arteriosclerosis. Transplant Proc (1971) 1.08

Preclinical cognitive decline in late middle-aged asymptomatic apolipoprotein E-e4/4 homozygotes: a replication study. J Neurol Sci (2001) 1.06

Further evidence linking late-onset Alzheimer disease with chromosome 12. JAMA (1999) 1.05

Complete genomic screen in late-onset familial Alzheimer's disease. Neurobiol Aging (1998) 1.02

APOE-epsilon4 predicts incident AD in Japanese-American men: the honolulu-asia aging study. Neurology (2000) 1.01

Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease. Ann Neurol (1997) 1.01

The relationship of APOE genotype to cognitive functioning in older African-American and Caucasian community residents. J Am Geriatr Soc (2001) 1.00

Activation of antigen-specific suppressor T cells in the presence of cyclosporin requires interactions between T cells of inducer and suppressor lineage. J Clin Invest (1983) 1.00

Lewy body and Alzheimer pathology in a family with the amyloid-beta precursor protein APP717 gene mutation. Acta Neuropathol (2000) 1.00

Risk of Alzheimer disease with the epsilon4 allele for apolipoprotein E in a population-based study of men aged 62-73 years. Alzheimer Dis Assoc Disord (1998) 0.99

[Development and validation of assessment instruments for shared decision making]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz (2004) 0.98

Tryptophan and 8-anilino-1-naphthalenesulfonate compete for binding to trp repressor. J Biol Chem (1989) 0.96

Transplantation of bone marrow in outbred dogs without graft-versus-host disease using total lymphoid irradiation. Transplantation (1979) 0.95

Alzheimer's disease and apolipoprotein E-4 allele in an Amish population. Ann Neurol (1996) 0.94

A Gilbert's syndrome UGT1A1 variant confers susceptibility to tranilast-induced hyperbilirubinemia. Pharmacogenomics J (2004) 0.94

Polymorphism in the TOMM40 gene modifies the risk of developing sporadic inclusion body myositis and the age of onset of symptoms. Neuromuscul Disord (2013) 0.92

Rosiglitazone does not improve cognition or global function when used as adjunctive therapy to AChE inhibitors in mild-to-moderate Alzheimer's disease: two phase 3 studies. Curr Alzheimer Res (2011) 0.92

Sleep consolidates the effector-independent representation of a motor skill. Neuroscience (2010) 0.91

No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease. Neurogenetics (1998) 0.91

The apolipoprotein E E4 allele and sex-specific risk of Alzheimer's disease. JAMA (1995) 0.91

Dementia with Lewy bodies and Alzheimer's disease. Acta Neuropathol (2001) 0.90

Preliminary report on the association of apolipoprotein E polymorphisms, with postoperative peak serum creatinine concentrations in cardiac surgical patients. Anesthesiology (2000) 0.88

Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism. Ann N Y Acad Sci (1996) 0.88

Cognitive function and apolipoprotein E in very old adults: findings from the Nun Study. J Gerontol B Psychol Sci Soc Sci (2000) 0.88

Evaluation of biologic sources of variation of leukocyte counts and other hematologic quantities using very precise automated analyzers. Am J Clin Pathol (1978) 0.88

Influence of the susceptibility genes apolipoprotein E-epsilon 4 and apolipoprotein E-epsilon 2 on the rate of disease expressivity of late-onset Alzheimer's disease. Arzneimittelforschung (1995) 0.88

A new technique for making häutchen preparations of unfixed aortic endothelium. J Atheroscler Res (1968) 0.87

Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease. Neurosci Lett (1994) 0.86

Within-day physiologic variation of leukocyte types in healthy subjects as assayed by two automated leukocyte differential analyzers. Am J Clin Pathol (1981) 0.85

Apolipoprotein E alleles in sporadic inclusion-body myositis and hereditary inclusion-body myopathy. Ann Neurol (1996) 0.85

Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice. Neurobiol Aging (1998) 0.85

Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice. J Cereb Blood Flow Metab (1998) 0.85

Relation of age and apolipoprotein E to cognitive function in Down syndrome adults. Neuroreport (1997) 0.84

Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations. FEBS Lett (1997) 0.84

Sources of physiological variation in differential leukocyte counting. Blood Cells (1985) 0.84

ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylation. Neurosci Lett (1995) 0.84

Genotypes and phenotypes for apolipoprotein E and Alzheimer disease in the Honolulu-Asia aging study. Clin Chem (2000) 0.83

Apolipoprotein E genotype and Lewy body disease. Neurology (1995) 0.83

APOE genotype is a risk factor for neuropathy severity in diabetic patients. Neurology (2003) 0.83

A proximal mouse chromosome 9 linkage map that further defines linkage groups homologous with segments of human chromosomes 11, 15, and 19. Genomics (1991) 0.83

The beta-phosphoro[35S]thioate analogue of UDP-Glc is efficiently utilized by the glucose phosphotransferase and is relatively resistant to hydrolytic degradation. Biochim Biophys Acta (1987) 0.83

Apolipoprotein E E4 allele and risk of dementia. JAMA (1995) 0.82

Early detection of Alzheimer's disease by combining apolipoprotein E and neuroimaging. Ann N Y Acad Sci (1996) 0.82

Apolipoprotein E epsilon2 does not increase risk of early-onset sporadic Alzheimer's disease. Ann Neurol (1997) 0.82

Uptake and internalization of exogenous apolipoprotein E3 by cultured human central nervous system neurons. Neurobiol Dis (1998) 0.81

Analysis of association between Alzheimer disease and the K variant of butyrylcholinesterase (BCHE-K). Neurosci Lett (1999) 0.81

Enhanced biological phosphorus removal in a sequencing batch reactor using propionate as the sole carbon source. Biotechnol Bioeng (2004) 0.81

Treatment of cadaveric renal transplant recipients with total lymphoid irradiation, antithymocyte globulin, and low-dose prednisone. Lancet (1985) 0.81