Published in Biochemistry on December 07, 1971
Muscular contraction. J Physiol (1974) 6.63
ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Cell Res (2011) 4.91
Cardiac myosin activation: a potential therapeutic approach for systolic heart failure. Science (2011) 4.36
The effects of inorganic phosphate and creatine phosphate on force production in skinned muscles from rat ventricle. J Physiol (1986) 2.97
The dependence of force and shortening velocity on substrate concentration in skinned muscle fibres from Rana temporaria. J Physiol (1984) 2.97
The force generated by a single kinesin molecule against an elastic load. Proc Natl Acad Sci U S A (1995) 2.85
Bovine brain kinesin is a microtubule-activated ATPase. Proc Natl Acad Sci U S A (1986) 2.80
Contraction of glycerinated muscle fibers as a function of the ATP concentration. Biophys J (1979) 2.72
Some self-consistent two-state sliding filament models of muscle contraction. Biophys J (1975) 2.65
Involvement of ATP in the nuclear and nucleolar functions of the 70 kd heat shock protein. EMBO J (1985) 2.64
The kinetics of magnesium adenosine triphosphate cleavage in skinned muscle fibres of the rabbit. J Physiol (1984) 2.64
The magnesium ion-dependent adenosine triphosphatase of myosin. Two-step processes of adenosine triphosphate association and adenosine diphosphate dissociation. Biochem J (1974) 2.57
Two step mechanism of phosphate release and the mechanism of force generation in chemically skinned fibers of rabbit psoas muscle. Biophys J (1991) 2.54
Decoration of spindle microtubules with Dynein: evidence for uniform polarity. J Cell Biol (1981) 2.44
Characterization of the myosin adenosine triphosphate (M.ATP) crossbridge in rabbit and frog skeletal muscle fibers. Biophys J (1988) 2.40
Initiation of active contraction by photogeneration of adenosine-5'-triphosphate in rabbit psoas muscle fibres. J Physiol (1984) 2.37
The dynamics of actin and myosin association and the crossbridge model of muscle contraction. Biochem J (1991) 2.36
The reversibility of adenosine triphosphate cleavage by myosin. Biochem J (1973) 2.33
Properties of flagellar "rigor waves" formed by abrupt removal of adenosine triphosphate from actively swimming sea urchin sperm. J Cell Biol (1974) 2.32
Two rigor states in skinned crayfish single muscle fibers. J Gen Physiol (1976) 2.15
Porters versus rowers: a unified stochastic model of motor proteins. J Cell Biol (1993) 2.15
Structure of the rigor actin-tropomyosin-myosin complex. Cell (2012) 2.14
A cross-bridge model that is able to explain mechanical and energetic properties of shortening muscle. Biophys J (1995) 2.13
The prepower stroke conformation of myosin V. J Cell Biol (2002) 2.12
Adenosine diphosphate and strain sensitivity in myosin motors. Philos Trans R Soc Lond B Biol Sci (2004) 2.11
Tension responses to quick length changes of glycerinated skeletal muscle fibres from the frog and tortoise. J Physiol (1974) 2.09
Myosin conformational states determined by single fluorophore polarization. Proc Natl Acad Sci U S A (1998) 2.07
A new concept for energy coupling in oxidative phosphorylation based on a molecular explanation of the oxygen exchange reactions. Proc Natl Acad Sci U S A (1973) 1.96
Metabolic changes associated with the slowing of relaxation in fatigued mouse muscle. J Physiol (1975) 1.95
Substructure of the outer dynein arm. J Cell Biol (1982) 1.92
Stiffness of skinned rabbit psoas fibers in MgATP and MgPPi solution. Biophys J (1986) 1.91
Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor. Proc Natl Acad Sci U S A (2002) 1.81
A large and distinct rotation of the myosin light chain domain occurs upon muscle contraction. Proc Natl Acad Sci U S A (1998) 1.75
X-ray evidence for two structural states of the actomyosin cross-bridge in muscle fibers. Proc Natl Acad Sci U S A (1984) 1.72
Reconstitution of contractile actomyosin bundles. Biophys J (2011) 1.71
Head-head and head-tail interaction: a general mechanism for switching off myosin II activity in cells. Mol Biol Cell (2008) 1.70
Rapid dissociation and reassociation of actomyosin cross-bridges during force generation: a newly observed facet of cross-bridge action in muscle. Proc Natl Acad Sci U S A (1991) 1.69
Structural mechanism of the recovery stroke in the myosin molecular motor. Proc Natl Acad Sci U S A (2005) 1.66
Kinetic and equilibrium analysis of the myosin ATPase. Methods Enzymol (2009) 1.66
A structural pathway for activation of the kinesin motor ATPase. EMBO J (2001) 1.64
Role of MgATP and MgADP in the cross-bridge kinetics in chemically skinned rabbit psoas fibers. Study of a fast exponential process (C) Biophys J (1989) 1.63
Parallel inhibition of active force and relaxed fiber stiffness in skeletal muscle by caldesmon: implications for the pathway to force generation. Proc Natl Acad Sci U S A (1991) 1.62
The magnesium-ion-dependent adenosine triphosphatase of bovine cardiac Myosin and its subfragment-1. Biochem J (1976) 1.62
Elastic lever-arm model for myosin V. Biophys J (2005) 1.62
High-energy phosphate metabolism and energy liberation associated with rapid shortening in frog skeletal muscle. J Physiol (1981) 1.60
The structural basis of muscle contraction. Philos Trans R Soc Lond B Biol Sci (2000) 1.59
The biochemical kinetics underlying actin movement generated by one and many skeletal muscle myosin molecules. Biophys J (2002) 1.59
Two independent mechanical events in the interaction cycle of skeletal muscle myosin with actin. Proc Natl Acad Sci U S A (2005) 1.57
Kinetic characterization of brush border myosin-I ATPase. Proc Natl Acad Sci U S A (1997) 1.56
Cross-bridge scheme and force per cross-bridge state in skinned rabbit psoas muscle fibers. Biophys J (1993) 1.54
Flash and smash: rapid freezing of muscle fibers activated by photolysis of caged ATP. Biophys J (1993) 1.53
The motor mechanism of myosin V: insights for muscle contraction. Philos Trans R Soc Lond B Biol Sci (2004) 1.53
Kinetic mechanism of myofibril ATPase. Biophys J (1994) 1.50
Direct visualization by electron microscopy of the weakly bound intermediates in the actomyosin adenosine triphosphatase cycle. Biophys J (1993) 1.50
Temperature dependence of mammalian muscle contractions and ATPase activities. Biophys J (1982) 1.46
Structural dynamics of frog muscle during isometric contraction. J Gen Physiol (1975) 1.46
Molecular model of muscle contraction. Proc Natl Acad Sci U S A (1999) 1.46
Study of the mechanism of vanadate inhibition of the dynein cross-bridge cycle in sea urchin sperm flagella. J Cell Biol (1979) 1.46
Reaction mechanism of the magnesium ion-dependent adenosine triphosphatase of frog muscle myosin and subfragment 1. Biochem J (1978) 1.44
Hypertrophic and dilated cardiomyopathy: four decades of basic research on muscle lead to potential therapeutic approaches to these devastating genetic diseases. Biophys J (2014) 1.44
Relaxation of muscle fibers with adenosine 5'-[gamma-thio]triphosphate (ATP[gamma S]) and by laser photolysis of caged ATP[gamma S]: evidence for Ca2+-dependent affinity of rapidly detaching zero-force cross-bridges. Proc Natl Acad Sci U S A (1988) 1.44
Head rotation or dissociation? A study of exponential rate processes in chemically skinned rabbit muscle fibers when MgATP concentration is changed. Biophys J (1978) 1.44
On the theory of muscle contraction: filament extensibility and the development of isometric force and stiffness. Biophys J (1996) 1.44
Fluorescent probes of the orientation of myosin regulatory light chains in relaxed, rigor, and contracting muscle. Biophys J (1996) 1.42
Mechanism of the actomyosin ATPase: effect of actin on the ATP hydrolysis step. Proc Natl Acad Sci U S A (1981) 1.40
Mechanochemical coupling in the myosin motor domain. II. Analysis of critical residues. PLoS Comput Biol (2006) 1.39
Hidden-Markov methods for the analysis of single-molecule actomyosin displacement data: the variance-Hidden-Markov method. Biophys J (2001) 1.36
The effects of MgADP on cross-bridge kinetics: a laser flash photolysis study of guinea-pig smooth muscle. J Physiol (1993) 1.35
Allosteric communication in myosin V: from small conformational changes to large directed movements. PLoS Comput Biol (2008) 1.34
Coupling between phosphate release and force generation in muscle actomyosin. Philos Trans R Soc Lond B Biol Sci (2004) 1.34
Structure-function studies of the myosin motor domain: importance of the 50-kDa cleft. Mol Biol Cell (1996) 1.34
Orientation changes in myosin regulatory light chains following photorelease of ATP in skinned muscle fibers. Biophys J (1996) 1.32
Pi release from myosin: a simulation analysis of possible pathways. Structure (2010) 1.31
Atomically detailed simulation of the recovery stroke in myosin by Milestoning. Proc Natl Acad Sci U S A (2010) 1.31
Effect of temperature on the working stroke of muscle myosin. Proc Natl Acad Sci U S A (2005) 1.30
Role of myosin heavy chain composition in the stretch activation response of rat myocardium. J Physiol (2006) 1.29
Sarcomere lattice geometry influences cooperative myosin binding in muscle. PLoS Comput Biol (2007) 1.27
Rotational dynamics of actin-bound intermediates of the myosin adenosine triphosphatase cycle in myofibrils. Biophys J (1994) 1.26
The molecular effects of skeletal muscle myosin regulatory light chain phosphorylation. Am J Physiol Regul Integr Comp Physiol (2009) 1.24
ADP binding to myosin cross-bridges and its effect on the cross-bridge detachment rate constants. J Gen Physiol (1987) 1.23
Effect of inorganic phosphate on the force and number of myosin cross-bridges during the isometric contraction of permeabilized muscle fibers from rabbit psoas. Biophys J (2008) 1.23
Interactions of dynein arms with b subfibers of Tetrahymena cilia: quantitation of the effects of magnesium and adenosine triphosphate. J Cell Biol (1980) 1.22
Crossbridge and non-crossbridge contributions to tension in lengthening rat muscle: force-induced reversal of the power stroke. J Physiol (2006) 1.21
Altered myofilament function depresses force generation in patients with nebulin-based nemaline myopathy (NEM2). J Struct Biol (2009) 1.20
The relationship of adenosine triphosphatase activity to tension and power output of insect flight muscle. J Physiol (1975) 1.20
The mechanism of the force response to stretch in human skinned muscle fibres with different myosin isoforms. J Physiol (2003) 1.19
Mechanokinetics of rapid tension recovery in muscle: the Myosin working stroke is followed by a slower release of phosphate. Biophys J (2004) 1.18
Phosphate burst in permeable muscle fibers of the rabbit. Biophys J (1986) 1.17
The elastic properties of the structurally characterized myosin II S2 subdomain: a molecular dynamics and normal mode analysis. Biophys J (2008) 1.17
Formation of a ternary complex: actin, 5'-adenylyl imidodiphosphate, and the subfragments of myosin. Proc Natl Acad Sci U S A (1978) 1.16
Changes in cross-bridge cycling underlie muscle weakness in patients with tropomyosin 3-based myopathy. Hum Mol Genet (2011) 1.16
Orientation of spin-labeled nucleotides bound to myosin in glycerinated muscle fibers. Biophys J (1987) 1.16
Optical depolarization changes on the diffraction pattern in the transition of skinned muscle fibers from relaxed to rigor state. Biophys J (1983) 1.15
Mechanical coupling between myosin molecules causes differences between ensemble and single-molecule measurements. Biophys J (2012) 1.15
Insights into the kinetics of Ca2+-regulated contraction and relaxation from myofibril studies. Pflugers Arch (2009) 1.14
Dependence of energy transduction in intact skeletal muscles on the time in tension. Biophys J (1977) 1.12
Thick filament proteins and performance in human heart failure. Heart Fail Rev (2005) 1.11
Myosin head configuration in relaxed insect flight muscle: x-ray modeled resting cross-bridges in a pre-powerstroke state are poised for actin binding. Biophys J (2003) 1.10
Contraction characteristics and ATPase activity of skeletal muscle fibers in the presence of antibody to myosin subfragment 2. Proc Natl Acad Sci U S A (1992) 1.09
The colchicine-binding protein of mammalian brain and its relation to microtubules. Biochemistry (1968) 12.96
The mechanism of action of colchicine. Binding of colchincine-3H to cellular protein. J Cell Biol (1967) 9.66
A structural change in the kinesin motor protein that drives motility. Nature (1999) 6.92
The mechanism of action of colchicine. Colchicine binding to sea urchin eggs and the mitotic apparatus. J Cell Biol (1967) 6.85
Isolation of a protein subunit from microtubules. J Cell Biol (1967) 5.37
Energetics and mechanism of actomyosin adenosine triphosphatase. Biochemistry (1976) 3.97
Mechanism of actomyosin ATPase and the problem of muscle contraction. CRC Crit Rev Biochem (1979) 3.83
Cytoplasmic filaments and tubules. Fed Proc (1968) 3.22
High throughput protein fold identification by using experimental constraints derived from intramolecular cross-links and mass spectrometry. Proc Natl Acad Sci U S A (2000) 2.96
Properties of the protein subunit of central-pair and outer-doublet microtubules of sea urchin flagella. J Cell Biol (1968) 2.91
Kinetic studies of the cooperative binding of subfragment 1 to regulated actin. Proc Natl Acad Sci U S A (1980) 2.74
X-ray diffraction of actively shortening muscle. Proc Natl Acad Sci U S A (1976) 2.59
Interacting head mechanism of microtubule-kinesin ATPase. J Biol Chem (1997) 2.57
Comparison of the myosin and actomyosin ATPase mechanisms of the four types of vertebrate muscles. J Mol Biol (1980) 2.46
Intermediate states of subfragment 1 and actosubfragment 1 ATPase: reevaluation of the mechanism. Biochemistry (1978) 2.35
Transient state phosphate production in the hydrolysis of nucleoside triphosphates by myosin. Biochemistry (1970) 2.11
Proposed definitions for the audit of postoperative infection: a discussion paper. Surgical Infection Study Group. Ann R Coll Surg Engl (1991) 2.06
Further purification and characterization of slime mold myosin and slime mold actin. Biochemistry (1969) 1.96
Management of abdominal aortic aneurysm. Br J Surg (1978) 1.95
Survey of operating theatres in Great Britain and Ireland. J Hosp Infect (1995) 1.92
Early return to work after repair of a unilateral inguinal hernia. Br J Surg (1983) 1.89
Isolation of an actomyosin-like protein complex from slime mold plasmodium and the separation of the complex into actin- and myosin-like fractions. Biochemistry (1969) 1.86
Kinetic mechanism of a monomeric kinesin construct. J Biol Chem (1997) 1.81
Myosin subfragment-1 attachment to actin. Expected effect on equatorial reflections. Biophys J (1978) 1.80
Transient kinetics of adenosine 5'-diphosphate and adenosine 5'-(beta, gamma-imidotriphosphate) binding to subfragment 1 and actosubfragment 1. Biochemistry (1982) 1.77
The ATPase mechanism of skeletal and smooth muscle acto-subfragment 1. J Biol Chem (1984) 1.71
Studies on the kinetics of formation and dissociation of the actomyosin complex. Biochemistry (1969) 1.60
Transient phase of adenosine triphosphate hydrolysis by myosin, heavy meromyosin, and subfragment 1. Biochemistry (1977) 1.60
Chemistry of muscle contraction. Annu Rev Biochem (1972) 1.59
Kinetic studies of calcium binding to regulatory complexes from skeletal muscle. J Biol Chem (1985) 1.57
Mechanism of microtubule kinesin ATPase. Biochemistry (1995) 1.55
The mechanism of regulation of actomyosin subfragment 1 ATPase. J Biol Chem (1987) 1.55
On the geometrical arrangement of the protein subunits of human serum low-density lipoprotein: evidence for a dodecahedral model. Proc Natl Acad Sci U S A (1969) 1.51
Kinetic mechanism of myofibril ATPase. Biophys J (1994) 1.50
Tublin: nucleotide binding and enzymic activity. J Mol Biol (1974) 1.46
Kinetic mechanism of kinesin motor domain. Biochemistry (1995) 1.46
Inhibition of actomyosin ATPase by vanadate. Proc Natl Acad Sci U S A (1982) 1.44
Control of DNA synthesis in mammalian cells in culture. Exp Cell Res (1965) 1.43
Equatorial X-ray reflections and cross arm movement in skeletal muscle. Nature (1975) 1.40
Low-angle x-ray diagrams from skeletal muscle: the effect of AMP-PNP, a non-hydrolyzed analogue of ATP. J Mol Biol (1975) 1.39
A kinetic study of the kinesin ATPase. J Biol Chem (1992) 1.37
Birefringence of muscle proteins and the problem of structural birefringence. Biochim Biophys Acta (1968) 1.35
Myosin-product complex and its effect on the steady-state rate of nucleoside triphosphate hydrolysis. Biochemistry (1970) 1.30
Expression, purification, ATPase properties, and microtubule-binding properties of the ncd motor domain. Biochemistry (1995) 1.29
Behaviours and rituals in the operating theatre. A report from the Hospital Infection Society Working Party on Infection Control in Operating Theatres. J Hosp Infect (2002) 1.25
Reactions of 1-N6-ethenoadenosine nucleotides with myosin subfragment 1 and acto-subfragment 1 of skeletal and smooth muscle. J Biol Chem (1984) 1.22
Characterization of a non-indexible equatorial x-ray reflection from frog sartorius muscle. J Mol Biol (1977) 1.15
Mapping the Treacher Collins syndrome locus to 5q31.3----q33.3. Genomics (1991) 1.14
Kinetics processivity and the direction of motion of Ncd. Biophys J (1999) 1.14
Intermediate states of actomyosin adenosine triphosphatase. Biochemistry (1976) 1.13
Alphoid DNA polymorphisms for chromosome 21 can be distinguished from those of chromosome 13 using probes homologous to both. Genomics (1991) 1.12
Intrinsic birefringence of poly-gamma-benzyl-L-glutamate, a helical polypeptide, and the theory of birefringence. Biophys J (1965) 1.12
Bowel preparation and the safety of colonoscopic polypectomy. Gastroenterology (1981) 1.09
Long saphenous vein stripping under local anaesthesia. Ann R Coll Surg Engl (1981) 1.08
Hydrolysis of nucleoside triphosphates by myosin during the transient state. Biochemistry (1969) 1.08
Kinetic mechanism of monomeric non-claret disjunctional protein (Ncd) ATPase. J Biol Chem (1997) 1.06
Cell motility. Variations on the theme of movement. Nature (1993) 1.05
The dissociation of 1-N6-ethenoadenosine diphosphate from regulated actomyosin subfragment 1. J Biol Chem (1987) 1.05
Biliary excretion of piperacillin. J Int Med Res (1983) 1.02
Reoperation for recurrent peptic ulceration. Br J Surg (1981) 1.00
Evidence for two unlinked loci regulating total serum IgE levels. Am J Hum Genet (1995) 0.99
Transient state kinetic studies of sarcoplasmic reticulum adenosine triphosphatase. J Biol Chem (1975) 0.98
Protein synthesis and specific dynamic action in crustaceans: effects of temperature. Comp Biochem Physiol A Mol Integr Physiol (2001) 0.98
Kinetic studies of calcium and magnesium binding to troponin C. J Biol Chem (1985) 0.97
High affinity binding of brain myosin-Va to F-actin induced by calcium in the presence of ATP. J Biol Chem (2001) 0.97
The effects of solvent environment on the optical rotatory dispersion parameters of polypeptides. II. Studies on poly-L-glutamic acid. Biophys J (1965) 0.95
The use of power spectral analysis to determine cardiorespiratory control in the short-horned sculpin Myoxocephalus scorpius. J Exp Biol (2004) 0.95
Dissociation constants of serotonin agonists in the canine basilar artery correlate to Ki values at the 5-HT1A binding site. J Pharmacol Exp Ther (1986) 0.95
Effect of modifier on three-step enzymic process: general rate equation. J Theor Biol (1974) 0.95
The cardiovascular responses of the freshwater turtle Trachemys scripta to warming and cooling. J Exp Biol (2004) 0.93
Effects of diet on spontaneous locomotor activity and oxygen consumption in Adriatic sturgeon (Acipenser naccarii). Fish Physiol Biochem (1995) 0.93
Abdominal wall biloma: an unusual complication of laparoscopic cholecystectomy. JSLS (1999) 0.93
Molecular modeling and in vitro activity of an HIV-1-encoded glutathione peroxidase. Proc Natl Acad Sci U S A (2000) 0.93
Transient state kinetic studies of proton liberation by myosin and subfragment 1. J Biol Chem (1975) 0.93
Effects of sublethal ammonia exposure on swimming performance in rainbow trout (Oncorhynchus mykiss). J Exp Biol (2001) 0.91
Spiroxatrine: a selective serotonin1A receptor antagonist. Eur J Pharmacol (1986) 0.90
Specific dynamic action in the shore crab, Carcinus maenas (L.), in relation to acclimation temperature and to the onset of the emersion response. Physiol Biochem Zool (2002) 0.89
Influence of oral mannitol bowel preparation on colonic microflora and the risk of explosion during endoscopic diathermy. Br J Surg (1981) 0.89
Tolerance of chronic hypercapnia by the European eel Anguilla anguilla. J Exp Biol (2003) 0.88
The effects of sustained exercise and hypoxia upon oxygen tensions in the red muscle of rainbow trout. J Exp Biol (2004) 0.88
Antiviral drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase occur in specific RNA structural regions. Antimicrob Agents Chemother (1994) 0.87
The differential cardio-respiratory responses to ambient hypoxia and systemic hypoxaemia in the South American lungfish, Lepidosiren paradoxa. Comp Biochem Physiol A Mol Integr Physiol (2001) 0.86
Complex physiological traits as biomarkers of the sub-lethal toxicological effects of pollutant exposure in fishes. Philos Trans R Soc Lond B Biol Sci (2007) 0.85
Exposure of brown trout, Salmo trutta, to a sub-lethal concentration of copper in soft acidic water: effects upon muscle metabolism and membrane potential. Aquat Toxicol (2000) 0.85
Evaluation of replication studies, combined data analysis, and analytical methods in complex diseases. Genet Epidemiol (1999) 0.85
Actin activation of the myosin ATPase: a kinetic analysis. J Theor Biol (1974) 0.85
Breast cancer in a trans-sexual man receiving hormone replacement therapy. Br J Surg (1995) 0.85
Patient management following uncomplicated elective gastrointestinal operations. Br J Clin Pract (1990) 0.84
The steady-state actomyosin ATPase: a further note. J Theor Biol (1975) 0.84
Correlation of molecular conformation and activity of reverse transcriptase inhibitors. Ann N Y Acad Sci (1990) 0.84
The effects of solvent environment on the optical rotatory dispersion parameters of polypeptides. I. Studies on poly-gamma-benzyl-L-glutamate. Biophys J (1965) 0.84
Retroviruses, ascorbate, and mutations, in the evolution of Homo sapiens. Free Radic Biol Med (1998) 0.84
The autonomic control and functional significance of the changes in heart rate associated with air breathing in the jeju, Hoplerythrinus unitaeniatus. J Exp Biol (2007) 0.84
Nervous control of heart rate: activity in the cardiac vagus of the dogfish. J Appl Physiol Respir Environ Exerc Physiol (1982) 0.84
The effect of progressive hypoxia on respiration in the dogfish (scyliorhinus canicula) at different seasonal temperatures. J Exp Biol (1975) 0.84