Published in J Biol Chem on January 10, 1974
Nitric oxide activates guanylate cyclase and increases guanosine 3':5'-cyclic monophosphate levels in various tissue preparations. Proc Natl Acad Sci U S A (1977) 4.90
Activation of guanylate cyclase by superoxide dismutase and hydroxyl radical: a physiological regulator of guanosine 3',5'-monophosphate formation. Proc Natl Acad Sci U S A (1977) 1.49
Cyclic GMP controls Rhodospirillum centenum cyst development. Mol Microbiol (2011) 1.18
Increased particulate and decreased soluble guanylate cyclase activity in regenerating liver, fetal liver, and hepatoma. Proc Natl Acad Sci U S A (1975) 1.17
Pitfalls in the use of lead nitrate for the histochemical demonstration of adenylate cyclase activity. J Cell Biol (1975) 0.89
Factors affecting the activity of guanylate cyclase in lysates of human blood platelets. Biochem J (1978) 0.80
cGMP levels in chronic cadmium disease and osteoarthritis. Br J Exp Pathol (1986) 0.78
Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP. Circ Res (1983) 6.42
The possible role of hydrogen sulfide as an endogenous neuromodulator. J Neurosci (1996) 6.04
Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. Science (1988) 5.56
The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide. Biochem Biophys Res Commun (1997) 4.93
Nitric oxide activates guanylate cyclase and increases guanosine 3':5'-cyclic monophosphate levels in various tissue preparations. Proc Natl Acad Sci U S A (1977) 4.90
Cyclic GMP synthesis and function. Pharmacol Rev (1987) 4.89
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc Natl Acad Sci U S A (1991) 4.50
T-lymphocyte entry into the central nervous system. J Neurosci Res (1991) 4.28
Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine. J Cyclic Nucleotide Res (1977) 3.70
Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli. Nature (1978) 3.60
Cyclic guanosine monophosphate as a mediator of vasodilation. J Clin Invest (1986) 3.59
Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells. Proc Natl Acad Sci U S A (1991) 3.15
Post-traumatic proliferative vitreoretinopathy. The epidemiologic profile, onset, risk factors, and visual outcome. Ophthalmology (1997) 2.94
Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylation. Nature (1984) 2.77
Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction. J Neurochem (1997) 2.62
Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase. Proc Natl Acad Sci U S A (1991) 2.58
Secretion cloning vectors in Escherichia coli. EMBO J (1984) 2.58
Activation of intestinal guanylate cyclase by heat-stable enterotoxin of Escherichia coli: studies of tissue specificity, potential receptors, and intermediates. J Infect Dis (1980) 2.52
Nobel laureates' letter to President Bush. Washington Post (2001) 2.43
Guanylate cyclase: activation by azide, nitro compounds, nitric oxide, and hydroxyl radical and inhibition by hemoglobin and myoglobin. Adv Cyclic Nucleotide Res (1978) 2.43
N omega-nitro-L-arginine: a potent inhibitor of endothelium-derived relaxing factor formation. Eur J Pharmacol (1990) 2.40
Histochemical mapping of nitric oxide synthase in the rat brain. Neuroscience (1992) 2.38
Isoforms of nitric oxide synthase. Characterization and purification from different cell types. Biochem Pharmacol (1991) 2.34
Endothelium-dependent and nitrovasodilator-induced relaxation of vascular smooth muscle: role of cyclic GMP. J Cyclic Nucleotide Protein Phosphor Res (1983) 2.34
Evolutionary adaptation of plasmid-encoded enzymes for degrading nylon oligomers. Nature (1984) 2.29
Atrial natriuretic factor elicits an endothelium-independent relaxation and activates particulate guanylate cyclase in vascular smooth muscle. Proc Natl Acad Sci U S A (1984) 2.26
Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides. Science (1992) 2.25
Epstein-Barr virus-associated lymphoproliferative disease in non-immunocompromised hosts: a status report and summary of an international meeting, 8-9 September 2008. Ann Oncol (2009) 2.20
A detailed linkage map of medaka, Oryzias latipes: comparative genomics and genome evolution. Genetics (2000) 2.19
Atrial natriuretic factor selectively activates particulate guanylate cyclase and elevates cyclic GMP in rat tissues. J Biol Chem (1984) 2.15
Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle. FEBS Lett (1993) 2.14
Novel effects of nitric oxide. Annu Rev Pharmacol Toxicol (2001) 2.08
Regulation of adenosine cyclic 3',5'-monophosphate and guanosine cyclic 3',5'-monophosphate levels and contractility in bovine tracheal smooth muscle. Mol Pharmacol (1977) 1.98
Regulation of glycogen metabolism in polymorphonuclear leukocytes. J Biol Chem (1970) 1.98
Nitric oxide synthase in macula densa regulates glomerular capillary pressure. Proc Natl Acad Sci U S A (1992) 1.93
Evaluation of immunoreactivity for erbB-2 protein as a marker of poor short term prognosis in gastric cancer. Cancer Res (1991) 1.92
Quantitative analysis of cytomegalovirus load using a real-time PCR assay. J Med Virol (2000) 1.84
Demonstration of a unique population of neurons with NADPH-diaphorase histochemistry. J Neurosci Methods (1983) 1.81
Direct imaging of DNA in living cells reveals the dynamics of chromosome formation. J Cell Biol (1999) 1.81
Activation of guanylate cyclase from rat liver and other tissues by sodium azide. J Biol Chem (1975) 1.77
Atypical adenomatous hyperplasia and bronchoalveolar lung carcinoma. Analysis by morphometry and the expressions of p53 and carcinoembryonic antigen. Am J Surg Pathol (1996) 1.77
Biochemical function of mouse minichromosome maintenance 2 protein. J Biol Chem (1998) 1.74
Chemical and immunological studies on mycobacterial polysaccharides. 1. Purification and properties of polysaccharides from human tubercle bacilli. J Bacteriol (1968) 1.74
Genetic analyses of GII.17 norovirus strains in diarrheal disease outbreaks from December 2014 to March 2015 in Japan reveal a novel polymerase sequence and amino acid substitutions in the capsid region. Euro Surveill (2015) 1.73
Human interleukin 6 is a direct promoter of maturation of megakaryocytes in vitro. Proc Natl Acad Sci U S A (1989) 1.69
Evidence for two different forms of guanylate cyclase in rat heart. J Biol Chem (1974) 1.68
Portal tumor thrombus due to gastrointestinal cancer. Abdom Imaging (1999) 1.67
Mapping of neural nitric oxide synthase in the rat suggests frequent co-localization with NADPH diaphorase but not with soluble guanylyl cyclase, and novel paraneural functions for nitrinergic signal transduction. J Histochem Cytochem (1992) 1.65
Remitting seronegative symmetrical synovitis with pitting edema associated with gastric carcinoma. J Rheumatol (1997) 1.64
Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages. Mol Pharmacol (1992) 1.63
Regional distribution of EDRF/NO-synthesizing enzyme(s) in rat brain. Biochem Biophys Res Commun (1990) 1.61
Amyloid peptides are toxic via a common oxidative mechanism. Proc Natl Acad Sci U S A (1995) 1.60
Human heart-type cytoplasmic fatty acid-binding protein (H-FABP) for the diagnosis of acute myocardial infarction. Clinical evaluation of H-FABP in comparison with myoglobin and creatine kinase isoenzyme MB. Clin Chem Lab Med (2000) 1.60
Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock. J Immunol (2000) 1.59
Visualization of detailed acetylcholinesterase fiber and neuron staining in rat brain by a sensitive histochemical procedure. J Histochem Cytochem (1986) 1.58
Co-purification of an atrial natriuretic factor receptor and particulate guanylate cyclase from rat lung. J Biol Chem (1986) 1.58
Identification and quantitation of T lymphocyte subsets found in the spinal cord of the Lewis rat during acute experimental allergic encephalomyelitis. J Immunol (1983) 1.58
Effects of sodium nitroprusside, nitroglycerin, and sodium azide on levels of cyclic nucleotides and mechanical activity of various tissues. J Cyclic Nucleotide Res (1977) 1.57
A simple, sensitive protein-binding assay for guanosine 3':5'-monophosphate. Proc Natl Acad Sci U S A (1971) 1.57
Clinical manifestations of primary herpes simplex virus type 1 infection in a closed community. Pediatrics (1991) 1.55
Reconstruction of the medial patellofemoral ligament for the treatment of habitual or recurrent dislocation of the patella in children. J Bone Joint Surg Br (2003) 1.50
Plasmid-determined enzymatic degradation of nylon oligomers. J Bacteriol (1983) 1.50
Inhibition of experimental proliferative vitreoretinopathy by retroviral vector-mediated transfer of suicide gene. Can proliferative vitreoretinopathy be a target of gene therapy? Ophthalmology (1995) 1.50
Multidrug resistant Mycobacterium leprae from patients with leprosy. Antimicrob Agents Chemother (2001) 1.50
Activation of guanylate cyclase by superoxide dismutase and hydroxyl radical: a physiological regulator of guanosine 3',5'-monophosphate formation. Proc Natl Acad Sci U S A (1977) 1.49
An activity in rat tissues that modifies nitrotyrosine-containing proteins. Proc Natl Acad Sci U S A (1998) 1.49
Effects of lipolytic and antilipolytic agents on cyclic 3',5'-adenosine monophosphate in fat cells. J Biol Chem (1971) 1.49
[Clinical effects of low-dose long-term erythromycin chemotherapy on diffuse panbronchiolitis]. Nihon Kyobu Shikkan Gakkai Zasshi (1987) 1.48
Caveolae in mesangial cells and caveolin expression in mesangial proliferative glomerulonephritis. Kidney Int (2001) 1.47
A simple and sensitive bioassay method for detection of EDRF with RFL-6 rat lung fibroblasts. Am J Physiol (1991) 1.47
Reversible inactivation of guanylate cyclase by mixed disulfide formation. J Biol Chem (1981) 1.46
Evaluation of brain metabolism in steno-occlusive carotid artery disease by proton MR spectroscopy: a correlative study with oxygen metabolism by PET. J Nucl Med (2000) 1.46
Cyclosporine-induced autoimmunity. Conditions for expressing disease, requirement for intact thymus, and potency estimates of autoimmune lymphocytes in drug-treated rats. J Exp Med (1986) 1.46
Binding of human minichromosome maintenance proteins with histone H3. J Biol Chem (1996) 1.45
Real-time quantitative reverse transcription-polymerase chain reaction for the detection of AML1-MTG8 fusion transcripts in t(8;21)-positive acute myelogenous leukemia. Leuk Res (2000) 1.45
Perivascular location and phenotypic heterogeneity of microglial cells in the rat brain. J Neuroimmunol (1990) 1.45
Activation of human peroxisome proliferator-activated receptor (PPAR) subtypes by pioglitazone. Biochem Biophys Res Commun (2000) 1.43
Vitamin E succinate inhibits proliferation and migration of retinal pigment epithelial cells in vitro: therapeutic implication for proliferative vitreoretinopathy. Graefes Arch Clin Exp Ophthalmol (1996) 1.43
The central cholinergic system studied by choline acetyltransferase immunohistochemistry in the cat. J Comp Neurol (1981) 1.42
Efficient identification of HLA-A*2402-restricted cytomegalovirus-specific CD8(+) T-cell epitopes by a computer algorithm and an enzyme-linked immunospot assay. Blood (2001) 1.42
NO, nitrotyrosine, and cyclic GMP in signal transduction. Med Sci Monit (2001) 1.42
Association of human herpesvirus 6 reactivation with the flaring and severity of drug-induced hypersensitivity syndrome. Br J Dermatol (2007) 1.42
The XAFS beamline BL01B1 at SPring-8. J Synchrotron Radiat (1999) 1.41
Quantitative analysis of Le(a) and Le(b) antigens in human saliva. Vox Sang (1994) 1.41
Hormone-induced biosynthesis of endothelium-derived relaxing factor/nitric oxide-like material in N1E-115 neuroblastoma cells requires calcium and calmodulin. Mol Pharmacol (1990) 1.41
Colocalization of nitric oxide synthase and NADPH-diaphorase in the myenteric plexus of the rat gut. Neurosci Lett (1992) 1.40
Interleukin-6 is a potent thrombopoietic factor in vivo in mice. Blood (1989) 1.40
Respiration effect of synthetic progestin in small doses in normal men. Chest (1989) 1.39
The efferent projections of the rat lateral habenular nucleus revealed by the PHA-L anterograde tracing method. Brain Res (1988) 1.39
Phosphorylation by calcium calmodulin-dependent protein kinase II and protein kinase C modulates the activity of nitric oxide synthase. Biochem Biophys Res Commun (1991) 1.39
High prevalence of serum apolipoprotein E4 isoprotein in rheumatoid arthritis patients with amyloidosis. Arthritis Rheum (1996) 1.39
Missense mutation of FUT1 and deletion of FUT2 are responsible for Indian Bombay phenotype of ABO blood group system. Biochem Biophys Res Commun (1997) 1.39
Isolation and characterization of mini-Tn5Km2 insertion mutants of enterohemorrhagic Escherichia coli O157:H7 deficient in adherence to Caco-2 cells. Infect Immun (2000) 1.39
Microvascular studies on the origins of perfusion-limited hypoxia. Br J Cancer Suppl (1996) 1.38
Thyrotropin secreting pituitary adenoma effectively treated with octreotide. Intern Med (1998) 1.38
Surgical treatment of patients with congenital vascular malformation-associated aneurysms. Eur J Vasc Endovasc Surg (2011) 1.38
A sphincterotome with variable-length wire for easier endoscopic sphincterotomy and quicker biliary drainage. Gastrointest Endosc (1995) 1.38