Published in Oncology on January 01, 1974
p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell (1998) 11.54
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature (2000) 7.46
Positive and negative elements regulate human interleukin 3 expression. Proc Natl Acad Sci U S A (1990) 7.44
Two small RNAs encoded by Epstein-Barr virus and complexed with protein are precipitated by antibodies from patients with systemic lupus erythematosus. Proc Natl Acad Sci U S A (1981) 7.43
Risk factors for doxorubicin-induced congestive heart failure. Ann Intern Med (1979) 6.00
Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene. Nat Genet (1997) 5.34
Detection and characterization of carcinoma cells in the blood. Proc Natl Acad Sci U S A (1998) 4.76
Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proc Natl Acad Sci U S A (1998) 4.07
Transferrin receptor is necessary for development of erythrocytes and the nervous system. Nat Genet (1999) 3.00
Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo. J Immunol (2000) 2.73
Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. J Clin Invest (2001) 2.49
The Maf transcription factors: regulators of differentiation. Trends Biochem Sci (1997) 2.38
The C282Y mutation causing hereditary hemochromatosis does not produce a null allele. Blood (1999) 2.27
Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner. Mol Cell Biol (1993) 2.05
Genes that modify the hemochromatosis phenotype in mice. J Clin Invest (2000) 1.99
CPG 7909, an immunostimulatory TLR9 agonist oligodeoxynucleotide, as adjuvant to Engerix-B HBV vaccine in healthy adults: a double-blind phase I/II study. J Clin Immunol (2004) 1.98
Intranasal immunization with CpG oligodeoxynucleotides as an adjuvant dramatically increases IgA and protection against herpes simplex virus-2 in the genital tract. J Immunol (2001) 1.84
Poliovirus replicase stimulation by terminal uridylyl transferase. J Biol Chem (1985) 1.81
Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs. Proc Natl Acad Sci U S A (1998) 1.81
Purification of a terminal uridylyltransferase that acts as host factor in the in vitro poliovirus replicase reaction. Proc Natl Acad Sci U S A (1986) 1.80
CpG DNA induces stronger immune responses with less toxicity than other adjuvants. Vaccine (2000) 1.80
Five-drug therapy for advanced breast cancer: a phase I study. Cancer Chemother Rep (1971) 1.77
Safety and immunogenicity of CPG 7909 injection as an adjuvant to Fluarix influenza vaccine. Vaccine (2004) 1.71
CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice. Proc Natl Acad Sci U S A (1998) 1.70
Iron-dependent regulation of the divalent metal ion transporter. FEBS Lett (2001) 1.68
The transcriptional integrator CREB-binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NF-E2. Mol Cell Biol (1997) 1.66
Divergent therapeutic and immunologic effects of oligodeoxynucleotides with distinct CpG motifs. J Immunol (2001) 1.65
In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction. Mol Cell Biol (1992) 1.61
DNA-mediated immunization to the hepatitis B surface antigen in mice: aspects of the humoral response mimic hepatitis B viral infection in humans. Proc Natl Acad Sci U S A (1995) 1.60
Superior hypogastric plexus block using a single needle and computed tomography guidance: description of a modified technique. Reg Anesth (1992) 1.58
Quantum confinement in size-selected, surface-oxidized silicon nanocrystals. Science (1993) 1.58
The role of CpG dinucleotides in DNA vaccines. Trends Microbiol (1998) 1.57
Complementary and alternative medicine use among children in the Washington, DC area. Ambul Pediatr (2002) 1.56
The G185R mutation disrupts function of the iron transporter Nramp2. Blood (1998) 1.56
Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice. Infect Immun (2001) 1.55
The molecular defect in hypotransferrinemic mice. Blood (2000) 1.54
Sexual adjustment, identification, and attitudes of patients with myelopathy. Arch Phys Med Rehabil (1966) 1.50
Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV. Hepatology (2000) 1.49
CpG DNA is a potent enhancer of systemic and mucosal immune responses against hepatitis B surface antigen with intranasal administration to mice. J Immunol (1998) 1.48
Hormonal therapy of breast cancer: new approaches and concepts. Ann Intern Med (1978) 1.48
Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders. Blood (2001) 1.43
Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE. J Biol Chem (2000) 1.41
Characteristics of Epstein-Barr virus hepatitis among patients with jaundice or acute hepatitis. Aliment Pharmacol Ther (2012) 1.37
Surgery for pulmonary aspergillosis. J Thorac Cardiovasc Surg (1969) 1.34
The utility of verbal autopsies for identifying HIV-1-related deaths in Haitian children. AIDS (1993) 1.34
Diethylstilbestrol: recommended dosages for different categories of breast cancer patients. Report of the Cooperative Breast Cancer Group. JAMA (1977) 1.33
Metastatic parathyroid carcinoma and hormonal chemotherapy. Case report and response to hexestrol. Ann Surg (1966) 1.32
Intrahepatic arterial infusion with 5-fluorouracil. Cancer (1971) 1.27
Chemotherapy of large bowel cancer. Cancer (1982) 1.25
Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2. Nature (1993) 1.23
Route and method of delivery of DNA vaccine influence immune responses in mice and non-human primates. Mol Med (1999) 1.22
Oral, intrarectal and intranasal immunizations using CpG and non-CpG oligodeoxynucleotides as adjuvants. Vaccine (2000) 1.22
Synthetic oligodeoxynucleotides containing CpG motifs enhance immunogenicity of a peptide malaria vaccine in Aotus monkeys. Vaccine (1999) 1.20
CpG oligodeoxynucleotides can circumvent the Th2 polarization of neonatal responses to vaccines but may fail to fully redirect Th2 responses established by neonatal priming. J Immunol (1999) 1.19
Further clinical studies with intrahepatic arterial infusion with 5-fluorouracil. Cancer (1975) 1.16
Adenine phosphoribosyltransferase deficiency and renal allograft dysfunction. Am J Kidney Dis (2001) 1.14
Trophic effect of ciliary neurotrophic factor on denervated skeletal muscle. Cell (1994) 1.14
Antithrombin III(AT-III) as a diagnostic aid in disseminated intravascular coagulation. Thromb Res (1977) 1.13
CPG 7909 adjuvant plus hepatitis B virus vaccination in HIV-infected adults achieves long-term seroprotection for up to 5 years. Clin Infect Dis (2008) 1.13
The Nramp2/DMT1 iron transporter is induced in the duodenum of microcytic anemia mk mice but is not properly targeted to the intestinal brush border. Blood (2000) 1.12
A mouse model of familial porphyria cutanea tarda. Proc Natl Acad Sci U S A (2001) 1.11
DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state. Proc Natl Acad Sci U S A (1996) 1.11
A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice. Genes Dev (2001) 1.11
p45 NF-E2 regulates expression of thromboxane synthase in megakaryocytes. EMBO J (1997) 1.09
The health of disabled people and the social determinants of health. Public Health (2011) 1.09
Novel bacterial P-type ATPases with histidine-rich heavy-metal-associated sequences. Biochem Biophys Res Commun (1994) 1.09
Primary squamous cell carcinoma of the breast: sensitivity to cisplatinum-based chemotherapy. J Surg Oncol (1995) 1.08
Daunorubicin and adriamycin in cancer treatment: an analysis of their roles and limitations. Cancer Treat Rep (1979) 1.07
CpG ODN can re-direct the Th bias of established Th2 immune responses in adult and young mice. FEMS Immunol Med Microbiol (2001) 1.06
Peripheral blood tumor cell load reflects the clinical activity of the disease in patients with carcinoma of the breast. Int J Oncol (2000) 1.05
Pulmonary and cardiovascular consequences of immediate fixation or conservative management of long-bone fractures. Arch Surg (1986) 1.03
Recent advances in disorders of iron metabolism: mutations, mechanisms and modifiers. Hum Mol Genet (2001) 1.01
Salmonella in slaughter pigs in Northern Ireland: prevalence and use of statistical modelling to investigate sample and abattoir effects. Int J Food Microbiol (2007) 1.01
Enhancing vaccines with immune stimulatory CpG DNA. Curr Opin Mol Ther (2001) 1.01
Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression. Blood (1997) 1.00
Regulation of beta-cell mass and function by the Akt/protein kinase B signalling pathway. Diabetes Obes Metab (2007) 0.99
Pyrosequencing and characterization of immune response genes from the American dog tick, Dermacentor variabilis (L.). Insect Mol Biol (2010) 0.99
An evaluation of 51 patients with hepatic artery infusion. Surg Gynecol Obstet (1966) 0.99
Phase I clinical and pharmacokinetic study of rebeccamycin analog NSC 655649 given daily for five consecutive days. J Clin Oncol (2001) 0.98
The potential of oligodeoxynucleotides as mucosal and parenteral adjuvants. Vaccine (2001) 0.97
Combined radiation therapy and 5-fluorouracil for advanced squamous cell carcinoma of the oral cavity and oropharynx: a randomized study. AJR Am J Roentgenol (1976) 0.97
Adriamycin cardiotoxicity in children: case reports, literature review, and risk factors. Cancer (1977) 0.96
High-performance liquid chromatographic analysis of penicillin V benzathine oral suspensions. J Pharm Sci (1979) 0.96
Hyperoxia-induced pulmonary vascular and lung abnormalities in young rats and potential for recovery. Pediatr Res (1985) 0.96
CpG DNA as mucosal adjuvant. Vaccine (1999) 0.96
Priming of immune responses to hepatitis B surface antigen in young mice immunized in the presence of maternally derived antibodies. FEMS Immunol Med Microbiol (2001) 0.95
The role of antitumor antibiotics in current oncologic practice. Cancer Chemother Pharmacol (1978) 0.95
Doxorubicin toxicity. Onycholysis, plantar callus formation, and epidermolysis. JAMA (1975) 0.94
Varied appearance of AIDS-related lymphoma in the chest. Radiology (1989) 0.94
CpG DNA is an effective oral adjuvant to protein antigens in mice. Vaccine (2000) 0.93
DNA-mediated immunization to the hepatitis B surface antigen. Activation and entrainment of the immune response. Ann N Y Acad Sci (1995) 0.93
The potential of CpG oligodeoxynucleotides as mucosal adjuvants. Crit Rev Immunol (2001) 0.93
Mucosal immunization of mice using CpG DNA and/or mutants of the heat-labile enterotoxin of Escherichia coli as adjuvants. Vaccine (2001) 0.93
Reduction of antigen expression from DNA vaccines by coadministered oligodeoxynucleotides. Antisense Nucleic Acid Drug Dev (1998) 0.92
Lymphoproliferative response during resolution and recurrence of naturally occurring gingivitis. J Periodontol (1977) 0.92
Multiple proteins interact with the nuclear inhibitory protein repressor element in the human interleukin-3 promoter. J Biol Chem (1995) 0.92
The Piromen test: a useful assay of bone marrow granulocyte reserves. Curr Ther Res Clin Exp (1969) 0.91
Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs. Gene Ther (2001) 0.91
Adjuvant effects of CpG oligodeoxynucleotides on responses against T-independent type 2 antigens. Immunology (2001) 0.91
Phage T3 DNA contains an exact copy of the 23 base-pair phage T7 RNA polymerase promoter sequence. J Mol Biol (1981) 0.90