Published in Curr Top Hematol on January 01, 1978
Two point mutations are responsible for G6PD polymorphism in Sardinia. Am J Hum Genet (1989) 1.42
Maternally transmitted severe glucose 6-phosphate dehydrogenase deficiency is an embryonic lethal. EMBO J (2002) 1.30
Cytogenetic Analysis of an SD Chromosome from a Natural Population of DROSOPHILA MELANOGASTER. Genetics (1980) 0.93
Molecular genetics of the glucose-6-phosphate dehydrogenase (G6PD) Mediterranean variant and description of a new G6PD mutant, G6PD Andalus1361A. Am J Hum Genet (1990) 0.93
Selectivity of proteases as a basis for tissue distribution of enzymes in hereditary deficiencies. Proc Natl Acad Sci U S A (1983) 0.85
Predicting the Kinetic Properties Associated with Redox Imbalance after Oxidative Crisis in G6PD-Deficient Erythrocytes: A Simulation Study. Adv Hematol (2011) 0.78
Cooperating G6PD mutations associated with severe neonatal hyperbilirubinemia and cholestasis. Pediatr Blood Cancer (2010) 0.75
Isolation of human glucose-6-phosphate dehydrogenase (G6PD) cDNA clones: primary structure of the protein and unusual 5' non-coding region. Nucleic Acids Res (1986) 3.86
Natural history of paroxysmal nocturnal hemoglobinuria. N Engl J Med (1995) 3.60
The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells. Cell (1993) 2.96
Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1. Nature (1999) 2.88
Therapeutic haemoglobin synthesis in beta-thalassaemic mice expressing lentivirus-encoded human beta-globin. Nature (2000) 2.84
Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells. J Natl Cancer Inst (1998) 2.75
Structural analysis of the X-linked gene encoding human glucose 6-phosphate dehydrogenase. EMBO J (1986) 2.64
Glucose-6-phosphate dehydrogenase deficient red cells: resistance to infection by malarial parasites. Science (1969) 2.21
Increased sickling of parasitised erythrocytes as mechanism of resistance against malaria in the sickle-cell trait. Lancet (1970) 2.11
A transgenic mouse model of sickle cell disorder. Nature (1990) 2.05
Circulating haemopoietic and endothelial progenitor cells are decreased in COPD. Eur Respir J (2006) 2.05
Adaptation of Plasmodium falciparum to glucose 6-phosphate dehydrogenase-deficient host red cells by production of parasite-encoded enzyme. Nature (1985) 2.04
Human CD1d-glycolipid tetramers generated by in vitro oxidative refolding chromatography. Proc Natl Acad Sci U S A (2001) 1.99
TbetaR-I(6A) is a candidate tumor susceptibility allele. Cancer Res (1999) 1.99
Blood group antigens and antibodies in Nigeria. Ann Trop Med Parasitol (1974) 1.94
Murine embryonic stem cells without pig-a gene activity are competent for hematopoiesis with the PNH phenotype but not for clonal expansion. J Clin Invest (1997) 1.86
Glucose-6-phosphate dehydrogenase and malaria. Greater resistance of females heterozygous for enzyme deficiency and of males with non-deficient variant. Lancet (1972) 1.83
Expression of platelet membrane glycoproteins and alpha-granule proteins by a human erythroleukemia cell line (HEL). EMBO J (1984) 1.82
Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A gene. EMBO J (1994) 1.80
Comparison of GdA and GdB activities in Nigerians. A study of the variation of the G6PD activity. Am J Hum Genet (1977) 1.79
Origin and spread of the glucose-6-phosphate dehydrogenase variant (G6PD-Mediterranean) in the Middle East. Am J Hum Genet (1990) 1.75
Specific methylation pattern at the 3' end of the human housekeeping gene for glucose 6-phosphate dehydrogenase. EMBO J (1984) 1.75
Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria genotype and phenotype are present in normal individuals. Proc Natl Acad Sci U S A (1999) 1.75
Mechanism of action of streptomycin in E. coli: interruption of the ribosome cycle at the initiation of protein synthesis. Proc Natl Acad Sci U S A (1968) 1.72
Genetics of red cells and susceptibility to malaria. Blood (1979) 1.71
cDNA sequences of human glucose 6-phosphate dehydrogenase cloned in pBR322. Nature (1981) 1.69
Type I transforming growth factor beta receptor maps to 9q22 and exhibits a polymorphism and a rare variant within a polyalanine tract. Cancer Res (1998) 1.68
Erythropoietin alone induces erythroid burst formation by human embryonic but not adult BFU-E in unicellular serum-free culture. Blood (1989) 1.64
High-level, erythroid-specific expression of the human alpha-globin gene in transgenic mice and the production of human hemoglobin in murine erythrocytes. Genes Dev (1989) 1.63
Production of hemolymphopoietic cytokines (IL-6, IL-8, colony-stimulating factors) by normal human astrocytes in response to IL-1 beta and tumor necrosis factor-alpha. J Immunol (1992) 1.59
In vivo telomere dynamics of human hematopoietic stem cells. Proc Natl Acad Sci U S A (1997) 1.58
Paroxysmal nocturnal hemoglobinuria: evidence for monoclonal origin of abnormal red cells. Blood (1970) 1.57
The heart in eosinophilic leukaemia. Afr J Med Sci (1970) 1.54
Apoptotic role of Fas/Fas ligand system in the regulation of erythropoiesis. Blood (1999) 1.54
Inhibition of insulin receptor binding by phorbol esters. Eur J Biochem (1982) 1.49
Indolent cutaneous prodrome of fatal HTLV-I infection. Lancet (1990) 1.48
Ultrastructural localization of lactoferrin and myeloperoxidase in human neutrophils by immunogold. Blood (1985) 1.47
Polymerase chain reaction automated at low cost. Nucleic Acids Res (1988) 1.46
Cell cycle-dependent initiation and lineage-dependent abrogation of GATA-1 expression in pure differentiating hematopoietic progenitors. Proc Natl Acad Sci U S A (1992) 1.45
Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer. Br J Cancer (1995) 1.44
Human embryonic hemopoiesis. Kinetics of progenitors and precursors underlying the yolk sac----liver transition. J Clin Invest (1986) 1.39
Serum erythropoietin levels in paroxysmal nocturnal haemoglobinuria: implications for therapy. Br J Haematol (1996) 1.38
Purchasing research from or for the NHS? J R Coll Physicians Lond (1995) 1.38
Glucose-6-phosphate dehydrogenase. Adv Hum Genet (1985) 1.38
Somatic mutations and cellular selection in paroxysmal nocturnal haemoglobinuria. Lancet (1994) 1.34
Paroxysmal nocturnal haemoglobinuria. Baillieres Clin Haematol (1989) 1.34
Parental occupation and other environmental factors in the etiology of leukemias and non-Hodgkin's lymphomas in childhood: a case-control study. Tumori (1990) 1.33
The molecular basis of glucose-6-phosphate dehydrogenase deficiency. Trends Genet (1992) 1.33
Different properties of glucose 6-phosphate dehydrogenase from human erythrocytes with normal and abnormal enzyme levels. Biochem Biophys Res Commun (1965) 1.33
Cytological mapping of the human glucose-6-phosphate dehydrogenase gene distal to the fragile-X site suggests a high rate of meiotic recombination across this site. Proc Natl Acad Sci U S A (1984) 1.30
Dyskeratosis congenita fibroblasts are abnormal and have unbalanced chromosomal rearrangements. Blood (1992) 1.30
Enhanced production of LPS-induced cytokines during differentiation of human monocytes to macrophages. Role of LPS receptors. J Immunol (1993) 1.29
Effects on differentiation by the promyelocytic leukemia PML/RARalpha protein depend on the fusion of the PML protein dimerization and RARalpha DNA binding domains. EMBO J (1996) 1.27
Genetic factors in malaria. Bull World Health Organ (1974) 1.24
Red cell glucose-6-phosphate dehydrogenase status and pyruvate kinase activity in a Nigerian population. Trop Med Int Health (2000) 1.24
Myeloid and megakaryocytic properties of K-562 cell lines. Cancer Res (1983) 1.23
Pregnancy in homozygous sickle-cell anaemia. J Obstet Gynaecol Br Commonw (1972) 1.21
Incomplete synthesis of N-glycans in congenital dyserythropoietic anemia type II caused by a defect in the gene encoding alpha-mannosidase II. Proc Natl Acad Sci U S A (1990) 1.19
"Pure" human hematopoietic progenitors: permissive action of basic fibroblast growth factor. Science (1990) 1.17
G6PD Mediterranean accounts for the high prevalence of G6PD deficiency in Kurdish Jews. Hum Genet (1993) 1.17
Variants of glucose-6-phosphate dehydrogenase are due to missense mutations spread throughout the coding region of the gene. Hum Mutat (1993) 1.15
Differential expression and functional role of GATA-2, NF-E2, and GATA-1 in normal adult hematopoiesis. J Clin Invest (1995) 1.13
Imbalance in X-chromosome expression: evidence for a human X-linked gene affecting growth of hemopoietic cells. Science (1979) 1.13
Bone marrow transplants for paroxysmal nocturnal haemoglobinuria. Br J Haematol (1999) 1.13
Two populations of erythroid cell progenitors in paroxysmal nocturnal hemoglobinuria. Blood (1984) 1.13
DNA rearrangements of immunoglobulin genes correlate with phenotypic markers in B-cell malignancies. Mol Biol Med (1984) 1.13
Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling. Mol Cell Biol (1997) 1.12
Both mutations in G6PD A- are necessary to produce the G6PD deficient phenotype. Hum Mol Genet (1992) 1.12
Analysis of beta, gamma, and delta T-cell receptor genes in mycosis fungoides and Sezary syndrome. Cancer (1991) 1.12
Astrocyte cultures from human embryonic brain: characterization and modulation of surface molecules by inflammatory cytokines. J Neurosci Res (1992) 1.12
Polyribosome depletion and blockage of the ribosome cycle by streptomycin in Escherichia coli. J Mol Biol (1969) 1.12
Relationship between the genes for glucose-6-phosphate dehydrogenase and for haemoglobin in a Nigerian population. Nature (1968) 1.11
Specific defect in N-acetylglucosamine incorporation in the biosynthesis of the glycosylphosphatidylinositol anchor in cloned cell lines from patients with paroxysmal nocturnal hemoglobinuria. Proc Natl Acad Sci U S A (1993) 1.11
Abnormal T-cell repertoire is consistent with immune process underlying the pathogenesis of paroxysmal nocturnal hemoglobinuria. Blood (2000) 1.10
Decreased malaria morbidity in the Tharu people compared to sympatric populations in Nepal. Ann Trop Med Parasitol (1988) 1.10
Promyelocytic leukemia-specific PML-retinoic acid alpha receptor fusion protein interferes with erythroid differentiation of human erythroleukemia K562 cells. Cancer Res (1995) 1.10
Dyskeratosis and ribosomal rebellion. Nat Genet (1998) 1.10
Paroxysmal nocturnal hemoglobinuria. Semin Hematol (1989) 1.10
Genetic heterogeneity of "normal" human erythrocyte glucose-6-phosphate dehydrogenase: an isoelectrophoretic polymorphism. Proc Natl Acad Sci U S A (1979) 1.10
Mild spherocytic hereditary elliptocytosis and altered levels of alpha- and gamma-adducins in beta-adducin-deficient mice. Blood (2000) 1.09
Transferrin receptor mediates uptake and presentation of hepatitis B envelope antigen by T lymphocytes. J Exp Med (1992) 1.09
Hematologically important mutations: glucose-6-phosphate dehydrogenase. Blood Cells Mol Dis (1997) 1.08
Glucose 6-phosphate dehydrogenase deficiency and sickle cell anemia: frequency and features of the association in an African community. Blood (1975) 1.08
Heterogeneity of T-cell beta-chain gene rearrangements in human leukaemias and lymphomas. EMBO J (1985) 1.08
Transferrin receptors: structure and function. Curr Top Hematol (1985) 1.08
An extensive search for RFLP in the human glucose-6-phosphate dehydrogenase locus has revealed a silent mutation in the coding sequence. Am J Hum Genet (1988) 1.07
Enzymic properties of different types of human erythrocyte glucose-6-phosphate dehydrogenase, with characterization of two new genetic variants. J Clin Invest (1968) 1.07
Retroviral-mediated gene transfer of a mutant H-ras gene into normal human bone marrow alters myeloid cell proliferation and differentiation. Exp Hematol (1994) 1.07
Tissue-specific levels of human glucose-6-phosphate dehydrogenase correlate with methylation of specific sites at the 3' end of the gene. Proc Natl Acad Sci U S A (1985) 1.07
Coordinate expression and proliferative role of HOXB genes in activated adult T lymphocytes. Mol Cell Biol (1994) 1.07
Regulation of the activity of glucose-6-phosphate dehydrogenase by NADP+ and NADPH. Biochim Biophys Acta (1967) 1.06
Regulation of transferrin receptors in human hematopoietic cell lines. J Biol Chem (1984) 1.06