Published in Theor Popul Biol on March 01, 1972
Evolutionary relationship of DNA sequences in finite populations. Genetics (1983) 40.67
Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data. Genetics (2003) 17.73
Description and power analysis of two tests for detecting recent population bottlenecks from allele frequency data. Genetics (1996) 12.75
DNA polymorphism detectable by restriction endonucleases. Genetics (1981) 10.13
The hitchhiking effect on the site frequency spectrum of DNA polymorphisms. Genetics (1995) 9.53
Extensive mitochondrial diversity within a single Amerindian tribe. Proc Natl Acad Sci U S A (1991) 9.35
Archaic African and Asian lineages in the genetic ancestry of modern humans. Am J Hum Genet (1997) 8.63
Model of effectively neutral mutations in which selective constraint is incorporated. Proc Natl Acad Sci U S A (1979) 7.83
Multilocus genetic structure in natural populations of Escherichia coli. Proc Natl Acad Sci U S A (1983) 7.42
Two-locus sampling distributions and their application. Genetics (2001) 7.42
The allele frequency spectrum in genome-wide human variation data reveals signals of differential demographic history in three large world populations. Genetics (2004) 7.00
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Lack of genic similarity between two sibling species of drosophila as revealed by varied techniques. Genetics (1976) 5.46
The pattern of neutral molecular variation under the background selection model. Genetics (1995) 5.03
Genomic regions exhibiting positive selection identified from dense genotype data. Genome Res (2005) 4.81
Random drift and culture change. Proc Biol Sci (2004) 4.11
Exome sequencing and the genetic basis of complex traits. Nat Genet (2012) 4.11
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New statistical tests of neutrality for DNA samples from a population. Genetics (1996) 3.75
Distribution of allelic frequencies in a finite population under stepwise production of neutral alleles. Proc Natl Acad Sci U S A (1975) 3.64
Mitochondrial DNA polymorphism reveals hidden heterogeneity within some Asian populations. Am J Hum Genet (1990) 3.64
Infinite allele model with varying mutation rate. Proc Natl Acad Sci U S A (1976) 3.56
Roles for HLA and KIR polymorphisms in natural killer cell repertoire selection and modulation of effector function. J Exp Med (2006) 3.50
The discovery of single-nucleotide polymorphisms--and inferences about human demographic history. Am J Hum Genet (2001) 3.50
Y-chromosomal DNA variation in Pakistan. Am J Hum Genet (2002) 3.35
Confidence interval for the number of selectively neutral amino acid polymorphisms. Proc Natl Acad Sci U S A (1987) 3.35
Stepwise mutation model and distribution of allelic frequencies in a finite population. Proc Natl Acad Sci U S A (1978) 3.29
The effect of intragenic recombination on the number of alleles in a finite population. Genetics (1978) 3.27
Genomic evolution during a 10,000-generation experiment with bacteria. Proc Natl Acad Sci U S A (1999) 3.27
Microsatellite variation in honey bee (Apis mellifera L.) populations: hierarchical genetic structure and test of the infinite allele and stepwise mutation models. Genetics (1995) 3.09
Nonequilibrium migration in human history. Genetics (1999) 2.93
Geographic uniformity of the Lyme disease spirochete (Borrelia burgdorferi) and its shared history with tick vector (Ixodes scapularis) in the Northeastern United States. Genetics (2002) 2.92
Natural selection and the frequency distributions of "silent" DNA polymorphism in Drosophila. Genetics (1997) 2.89
Genetic and linguistic differentiation in the Americas. Proc Natl Acad Sci U S A (1993) 2.85
How pathogens drive genetic diversity: MHC, mechanisms and misunderstandings. Proc Biol Sci (2010) 2.76
Gene genealogies in a metapopulation. Genetics (2001) 2.74
Cloning a selected fragment from a human DNA 'fingerprint': isolation of an extremely polymorphic minisatellite. Nucleic Acids Res (1986) 2.70
The amount of DNA polymorphism maintained in a finite population when the neutral mutation rate varies among sites. Genetics (1996) 2.69
Complex population structure in African village dogs and its implications for inferring dog domestication history. Proc Natl Acad Sci U S A (2009) 2.42
A genome scan for positive selection in thoroughbred horses. PLoS One (2009) 2.42
Bayesian analysis suggests that most amino acid replacements in Drosophila are driven by positive selection. J Mol Evol (2003) 2.39
Favorable and unfavorable HLA class I alleles and haplotypes in Zambians predominantly infected with clade C human immunodeficiency virus type 1. J Virol (2002) 2.38
A two-locus neutrality test: applications to humans, E. coli and lodgepole pine. Genetics (1986) 2.34
Trading genes along the silk road: mtDNA sequences and the origin of central Asian populations. Am J Hum Genet (1998) 2.32
Intraspecific variation in population gene diversity and effective population size correlates with the mating system in plants. Proc Natl Acad Sci U S A (1991) 2.26
Estimation of effective population sizes from data on genetic markers. Philos Trans R Soc Lond B Biol Sci (2005) 2.25
Testing neutrality in subdivided populations. Genetics (1982) 2.25
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mtDNA and the origin of the Icelanders: deciphering signals of recent population history. Am J Hum Genet (2000) 2.23
Balancing selection and heterogeneity across the classical human leukocyte antigen loci: a meta-analytic review of 497 population studies. Hum Immunol (2008) 2.22
Estimating Scandinavian and Gaelic ancestry in the male settlers of Iceland. Am J Hum Genet (2000) 2.22
The sensitivity of gel electrophoresis as a detector of genetic variation. Genetics (1979) 2.18
Estimation of mutation rate from rare protein variants. Am J Hum Genet (1977) 2.15
Allelic variation in human mitochondrial genes based on patterns of restriction site polymorphism. Proc Natl Acad Sci U S A (1986) 2.13
Population amalgamation and genetic variation: observations on artificially agglomerated tribal populations of Central and South America. Am J Hum Genet (1988) 2.13
Drift as a mechanism for cultural change: an example from baby names. Proc Biol Sci (2003) 2.03
Alu evolution in human populations: using the coalescent to estimate effective population size. Genetics (1997) 2.03
Origins of the coalescent. 1974-1982. Genetics (2000) 2.03
Description and validation of a method for simultaneous estimation of effective population size and mutation rate from human population data. Proc Natl Acad Sci U S A (1989) 2.02
Comparative metagenomics and population dynamics of the gut microbiota in mother and infant. Genome Biol Evol (2010) 2.00
Diverging trends between heterozygosity and allelic richness during postglacial colonization in the European beech. Genetics (2001) 1.96
Multilocus phylogeography and phylogenetics using sequence-based markers. Genetica (2008) 1.92
Microsatellite polymorphism in natural populations of the wild plant Arabidopsis thaliana. Genetics (1997) 1.89
Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing data. Front Microbiol (2012) 1.89
Origin and differentiation of human mitochondrial DNA. Am J Hum Genet (1989) 1.86
An ancient common origin of aboriginal Australians and New Guinea highlanders is supported by alpha-globin haplotype analysis. Am J Hum Genet (1996) 1.82
Allele multiplicity in simple Mendelian disorders. Am J Hum Genet (1982) 1.82
Recombination within and between the human insulin and beta-globin gene loci. Proc Natl Acad Sci U S A (1983) 1.82
Where have all the interactions gone? Estimating the coverage of two-hybrid protein interaction maps. PLoS Comput Biol (2007) 1.81
mtDna and the islands of the North Atlantic: estimating the proportions of Norse and Gaelic ancestry. Am J Hum Genet (2001) 1.81
Genetic consequences of sequential founder events by an island-colonizing bird. Proc Natl Acad Sci U S A (2002) 1.81
Haplotype and missing data inference in nuclear families. Genome Res (2004) 1.69
Using approximate Bayesian computation to estimate tuberculosis transmission parameters from genotype data. Genetics (2006) 1.68
DNA variation at the rp49 gene region of Drosophila simulans: evolutionary inferences from an unusual haplotype structure. Genetics (2001) 1.64
Protein variants in Hiroshima and Nagasaki: tales of two cities. Am J Hum Genet (1988) 1.63
Statistical analyses of Drosophila and human protein polymorphisms. Proc Natl Acad Sci U S A (1975) 1.63
Microevolution of the Chibcha-speaking peoples of lower Central America: rare genes in an Amerindian complex. Am J Hum Genet (1992) 1.61
PyPop update--a software pipeline for large-scale multilocus population genomics. Tissue Antigens (2007) 1.60
Simultaneous estimation of all the parameters of a stepwise mutation model. Genetics (1998) 1.60
Signature of recent historical events in the European Y-chromosomal STR haplotype distribution. Hum Genet (2005) 1.54
Methods for estimating gene frequencies and detecting selection in bacterial populations. Genetics (2000) 1.54
Genealogical structure among alleles regulating self-incompatibility in natural populations of flowering plants. Genetics (1997) 1.54
The IBD process along four chromosomes. Theor Popul Biol (2007) 1.54
Allelic richness following population founding events--a stochastic modeling framework incorporating gene flow and genetic drift. PLoS One (2014) 1.51
Population genetics of Caenorhabditis elegans: the paradox of low polymorphism in a widespread species. Genetics (2003) 1.49
Implications of the circumpolar genetic structure of polar bears for their conservation in a rapidly warming Arctic. PLoS One (2015) 1.48
The sampling distribution of disease-associated alleles. Genetics (1997) 1.46
Adaptive evolution of conserved noncoding elements in mammals. PLoS Genet (2007) 1.45
Neutral genetic markers and conservation genetics: simulated germplasm collections. Genetics (1996) 1.44
Analyses of the age of genes and the first arrival times in a finite population. Genetics (1983) 1.43
Methods for human demographic inference using haplotype patterns from genomewide single-nucleotide polymorphism data. Genetics (2009) 1.42
Maintenance of genetic variability under mutation and selection pressures in a finite population. Proc Natl Acad Sci U S A (1977) 1.41
Statistical tests of the coalescent model based on the haplotype frequency distribution and the number of segregating sites. Genetics (2005) 1.41
Contrasting evolutionary histories among tightly linked HLA loci. Am J Hum Genet (1986) 1.39
Phylogeography and population history of Atlantic mackerel (Scomber scombrus L.): a genealogical approach reveals genetic structuring among the eastern Atlantic stocks. Proc Biol Sci (2000) 1.39
The stem cell population of the human colon crypt: analysis via methylation patterns. PLoS Comput Biol (2007) 1.38
Likelihoods and simulation methods for a class of nonneutral population genetics models. Genetics (2001) 1.37
Signatures of demographic history and natural selection in the human major histocompatibility complex Loci. Genetics (2006) 1.37
Identity by descent: variation in meiosis, across genomes, and in populations. Genetics (2013) 1.37
Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet (1993) 51.42
A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. Am J Hum Genet (1998) 15.76
The TDT and other family-based tests for linkage disequilibrium and association. Am J Hum Genet (1996) 11.61
Estimation of genetic variation at the DNA level from restriction endonuclease data. Proc Natl Acad Sci U S A (1981) 4.71
A note on the sampling theory for infinite alleles and infinite sites models. Theor Popul Biol (1974) 3.70
Properties of equilibria in multi-locus genetic systems. Genetics (1977) 2.63
A resolution of the ascertainment sampling problem. I. Theory. Theor Popul Biol (1986) 2.42
Concepts of substitutional load in finite populations. Theor Popul Biol (1972) 2.15
Aspects of parameter estimation in ascertainment sampling schemes. Am J Hum Genet (1982) 2.06
Mean fitness increases when fitnesses are additive. Nature (1969) 1.91
The TDT reveals linkage and linkage disequilibrium in a rare disease. Genet Epidemiol (1995) 1.69
Linkage-disequilibrium mapping without genotyping. Nat Genet (1998) 1.52
A generalized fundamental theorem of natural selection. Genetics (1969) 1.49
Multifactorial analysis of family data ascertained through truncation: a comparative evaluation of two methods of statistical inference. Am J Hum Genet (1988) 1.47
The eigenvalues of the neutral alleles process. Theor Popul Biol (1975) 1.46
A resolution of the ascertainment sampling problem. III. Pedigrees. Am J Hum Genet (1988) 1.44
A resolution of the ascertainment sampling problem. II. Generalizations and numerical results. Am J Hum Genet (1988) 1.43
Editorial: Statistical inference--Bayesian and non-Bayesian. Am J Hum Genet (1976) 1.39
Estimating parameters of the family-size distribution in ascertainment sampling schemes: numerical results. Biometrics (1984) 1.35
Ascertainment considerations in the analysis of affected sib shared haplotype data. Genet Epidemiol Suppl (1986) 1.34
Some simulation results for the neutral allele model, with interpretations. Theor Popul Biol (1974) 1.31
Population genetics theory in relation to the neutralist-selectionist controversy. Adv Hum Genet (1977) 1.27
Significance testing for direct identity-by-descent mapping. Ann Hum Genet (1999) 1.12
Conditional diffusion processes in population genetics. Theor Popul Biol (1973) 1.03
Maximum likelihood estimation of genetic parameters of HLA-linked diseases using data from families of various sizes. Am J Hum Genet (1984) 1.02
Remarks on the evolutionary effect of natural selection. Genetics (1976) 1.02
The transmission/disequilibrium test detects cosegregation and linkage. Am J Hum Genet (1994) 0.99
Conditional and unconditional likelihood solutions. Am J Hum Genet (1984) 0.96
The maintenance of alleles by mutation--Monte Carlo results for normal and self-sterility populations. Heredity (Edinb) (1966) 0.94
Remarks on the substitutional load. Theor Popul Biol (1970) 0.93
The effects of a known family-size distribution on the estimation of genetic parameters. Am J Hum Genet (1986) 0.89
Tay-Sachs disease and theoretical population genetics. Am J Hum Genet (1978) 0.86
Testing for increased mutation rate for neutral alleles. Theor Popul Biol (1973) 0.84
TDT clarification. Am J Hum Genet (1999) 0.84
Heterozygosity mapping of partially congenic lines: mapping of a semidominant neurological mutation, Wheels (Whl), on mouse chromosome 4. Genetics (1995) 0.83
Human orientation with restricted sensory information: no evidence for magnetic sensitivity. Perception (1984) 0.82
The probability of survival of a mutant. Heredity (Edinb) (1967) 0.78
Linkage and the evolution of dominance. Heredity (Edinb) (1966) 0.76
Is knowing the age-order of alleles in a sample useful in testing for selective neutrality? Genetics (1989) 0.75
Statistical properties of maximum likelihood estimators for genetic parameters of HLA-linked diseases. Am J Hum Genet (1985) 0.75
Inference problems in population genetics: DNA sequences, restriction endonucleases and ascertainment sampling. Proc R Soc Lond B Biol Sci (1983) 0.75
A note on the variance of the number of loci having a given gene frequency. Genetics (1975) 0.75
A note on the fixation of a favoured gene. Heredity (Edinb) (1969) 0.75
Theoretical and simulation results relating to the neutral allele theory. Theor Popul Biol (1972) 0.75
Effects of ovine follicular fluid on plasma LH and FSH secretion in ovariectomized ewes to indicate the site of action of inhibin. J Reprod Fertil (1986) 0.75
Considerations of statistical power in the shared-haplotypes test. Stat Med (1986) 0.75
Analysis of neutrality in protein polymorphism. Science (1974) 0.75