Published in J Clin Invest on August 01, 1973
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Pharmacology of uricosuric drugs. Ann Rheum Dis (1974) 0.84
Quantitative estimation of urate transport in nephrons in relation to urinary excretion employing benzbromarone-loading urate clearance tests in cases of hyperuricemia. Nephron Extra (2011) 0.78
Hypouricaemia and increased renal urate clearance associated with hyperparathyroidism. Ann Rheum Dis (1976) 0.75
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A potent new uricosuric agent, the sulfoxide metabolite of the phenylbutazone analogue, G-25671. J Pharmacol Exp Ther (1957) 2.20
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Factors affecting urate excretion following diuretic administration in man. Am J Med (1969) 1.46
Studies of hyperuricemia produced by pyrazinamide. Am J Med (1957) 1.38
The contribution of residual nephrons within the chronically diseased kidney to urate homeostasis in man. Am J Med (1967) 1.34
Studies on the renal excretion of salicylate in the dog. Bull Johns Hopkins Hosp (1959) 1.33
Evidence for altered renal urate reabsorption during changes in volume of the extracellular fluid. J Lab Clin Med (1969) 1.22
A three-component system for regulation of renal excretion of uric acid in man. Trans Assoc Am Physicians (1961) 1.22
Renal function in gout. 3. Estimation of tubular secretion and reabsorption of uric acid by use of pyrazinamide (pyrazinoic acid). Am J Med (1969) 1.20
The renal mechanism for urate homeostasis in normal man. Am J Med (1967) 1.16
Effect of pyrazinamide and pyrazinoic acid on urate clearance and other discrete renal functions. Proc Soc Exp Biol Med (1957) 1.10
Uricosuric drugs, with special reference to probenecid and sulfinpyrazone. Adv Pharmacol (1966) 1.10
MUTUAL SUPPRESSION OF THE URICOSURIC EFFECTS OF SULFINPYRAZONE AND SALICYLATE: A STUDY IN INTERACTIONS BETWEEN DRUGS. J Clin Invest (1963) 1.09
A study of the inverse relationship between pKa and rate of renal excretion of phenylbutazone analogs in man and dog. Am J Med (1960) 1.08
Diminished renal urate secretion per nephron as a basis for primary gout. Ann Intern Med (1970) 1.07
Tubular secretion of urate in the dog. Am J Physiol (1960) 0.98
The physiological disposition of chlorothiazide (diuril) in the dog. J Pharmacol Exp Ther (1959) 0.96
Handling of uric acid by the rat kidney. I. Microanalysis of uric acid in proximal tubular fluid. Pflugers Arch (1971) 0.95
Pharmacology of pyrazinamide: metabolic and renal function studies related to the mechanism of drug-induced urate retention. J Pharmacol Exp Ther (1972) 0.93
Urate-2-14C transport in the rat nephron. J Clin Invest (1971) 0.92
EXPERIMENTAL URATE NEROPATHY: STUDIES OF THE DISTRIBUTION OF URATE IN RENAL TISSUE. Nephron (1964) 0.89
FACTORS INFLUENCING RENAL EXCRETION OF FOREIGN ORGANIC ACIDS. Am J Physiol (1964) 0.89
Bidirectional urate transport limited to the proximal tubule in dogs. Am J Physiol (1968) 0.86
Renal excretion of uric acid in the dog. Am J Physiol (1968) 0.86
Renal urate transport in the chimpanzee. Am J Physiol (1971) 0.84
Handling of uric acid by the rat kidney. II. Microperfusion studies on bidirectional transport of uric acid in the proximal tubule. Pflugers Arch (1972) 0.82
Renal transport of uric acid in the guinea pig. Am J Physiol (1968) 0.82
[Study in man of the kinetics of the appearance of uric acid 2-14C in the urine]. Nephron (1968) 0.81
Effect of glycine loading on plasma and urinary uric acid and amino acids in normal and gouty subjects. Am J Med (1970) 0.79
The distribution of urate in human and primate kidney. Proc Soc Exp Biol Med (1968) 0.79
Renal excretion and uricosuric properties of halofenate, a hypolipidemic-uricosuric agent, in the chimpanzee. J Pharmacol Exp Ther (1972) 0.78
Uricosuric potency of 2-substituted analogs of probenecid. J Pharmacol Exp Ther (1972) 0.78
Renal effects of uricosuric agents in the chimpanzee. J Pharmacol Exp Ther (1971) 0.77
LOCALIZATION AND PYRAZINAMIDE INHIBITION OF DISTAL TRANSTUBULAR MOVEMENT OF URIC ACID-2-C14 WITH A MODIFIED STOP-FLOW TECHNIQUE. J Clin Invest (1965) 0.77
The renal mechanisms for the excretion of m-hydroxybenzoic acid in Cebus monkeys: relationship to urate transport. J Pharmacol Exp Ther (1971) 0.77
Studies on renal urate secretion in the dog. J Pharmacol Exp Ther (1971) 0.77
Effects of mercurial diuretics on the renal tubular transport of p-aminohippurate and diodrast in the chimpanzee. J Pharmacol Exp Ther (1972) 0.76
Biosynthesis of bacterial lipopolysaccharide. V. Lipid-linked intermediates in the biosynthesis of the O-antigen groups of Salmonella typhimurium. Proc Natl Acad Sci U S A (1965) 2.00
Intestinal bile salt transport: structure-activity relationships and other properties. Am J Physiol (1966) 1.34
Effects of some pyrazinecarboxamides on sodium transport in frog skin. Br J Pharmacol (1978) 1.29
Biosynthesis of a bacterial lipopolysaccharide. VI. Mechanism of incorporation of abequose into the O-antigen of Salmonella typhimurium. J Biol Chem (1968) 1.26
Biochemical aspects of structure, differentiation and morphogenesis in microorganisms. Mechanism of biosynthesis of the lipopolysaccharide of Salmonella. Fed Proc (1967) 1.23
Dextran-bound inhibitors of carbonic anhydrase. J Pharmacol Exp Ther (1981) 1.18
On the hypocalciuric action of chlorothiazide. J Clin Invest (1974) 1.10
Function of proximal tubule carbonic anhydrase defined by selective inhibition. Am J Physiol (1983) 1.01
Saluretic and uricosuric effects of (6, 7-dichloro-2-methyl=1-oxo-2-phenyl-5-indanyloxy) acetic acid (MK-196) in the chimpanzee. J Pharmacol Exp Ther (1977) 0.96
Novel renin inhibitors containing the amino acid statine. Nature (1983) 0.93
Pharmacology of pyrazinamide: metabolic and renal function studies related to the mechanism of drug-induced urate retention. J Pharmacol Exp Ther (1972) 0.93
Bidirectional active transport of m-hydroxybenzoate in proximal tubule of dogs. Am J Physiol (1970) 0.91
Renal actions of vitamin D in D-deficient rats. Am J Physiol (1974) 0.90
Bidirectional transport of taurocholate by the proximal tubule of the dog. Am J Physiol (1968) 0.88
Biosynthesis of O-antigen in Salmonella typhimurium. Ann N Y Acad Sci (1966) 0.88
Relationship between clearances of Ca and Na: effect of distal diuretics and PTH. Am J Physiol (1976) 0.88
Role of the intestine during the enterohepatic circulation of bile salts. Gastroenterology (1967) 0.88
Factors influencing 45 Ca metabolism in brain and other organs in vivo. Proc Soc Exp Biol Med (1971) 0.87
Bidirectional urate transport limited to the proximal tubule in dogs. Am J Physiol (1968) 0.86
Renal excretion of urate: factors determining the actions of drugs. Kidney Int (1980) 0.85
The role of volume contraction in the hypocalciuric action of chlorothiazide. Kidney Int (1976) 0.85
Renal urate transport in the chimpanzee. Am J Physiol (1971) 0.84
Functional characteristics of renal urate transport in the Cebus monkey. Am J Physiol (1970) 0.83
Renal excretion of cimetidine. J Pharmacol Exp Ther (1981) 0.81
Renal excretion of a slauretic-uricosuric agent (MK-196) and interaction with a urate-retaining drug, pyrazinoate, in the chimpanzee. J Pharmacol Exp Ther (1977) 0.81
Urate transport in the nephron. Am J Physiol (1979) 0.80
The ileal bile salt transport system: effect of the charged state of the substrate on activity. Biochim Biophys Acta (1967) 0.79
Diuretic-induced uricosuria: interaction with pyrazinoate transport in man. J Pharmacol Exp Ther (1977) 0.79
Renal excretion and uricosuric properties of halofenate, a hypolipidemic-uricosuric agent, in the chimpanzee. J Pharmacol Exp Ther (1972) 0.78
Uricosuric potency of 2-substituted analogs of probenecid. J Pharmacol Exp Ther (1972) 0.78
Effects of dinitrophenol and cyanide on TPAH and Na reabsorption. Am J Physiol (1971) 0.78
Does intracellular sodium regulate sodium transport across the mucosal surface of frog skin? Biochim Biophys Acta (1978) 0.78
Effects of pyrazinoate and p-aminohippurate on renal urate excretion by the dog and guinea pig. J Pharmacol Exp Ther (1983) 0.78
Excretion of urate by the kidneys of Cebus monkeys: a micropuncture study. Am J Physiol (1973) 0.77
Renal effects of uricosuric agents in the chimpanzee. J Pharmacol Exp Ther (1971) 0.77
The renal mechanisms for the excretion of m-hydroxybenzoic acid in Cebus monkeys: relationship to urate transport. J Pharmacol Exp Ther (1971) 0.77
Dissociation of calcium and sodium clearances in patients with hypoparathyroidism by infusion of chlorothiazide. Metabolism (1975) 0.77
Adenine nucleotides and PAH transport in slices of renal cortex: effects of DNP and CN - . Am J Physiol (1972) 0.77
Urate excretion. Annu Rev Med (1977) 0.76
Effects of mercurial diuretics on the renal tubular transport of p-aminohippurate and diodrast in the chimpanzee. J Pharmacol Exp Ther (1972) 0.76
Diuretic and uricosuric activity of 6,7-dichloro-2,3-dihydro-5-(2-thienylcarbonyl)benzofuran-2-carboxylic acid and stereoisomers in chimpanzee, dog and rat. J Pharmacol Exp Ther (1980) 0.75
Inability of indomethacin to modify hydrochlorothiazide diuresis and natriuresis by the chimpanzee kidney. J Pharmacol Exp Ther (1980) 0.75
(Acylaryloxy)acetic acid diuretics. 2. (2-Alkyl-2-aryl-1-oxo-5-indanyloxy)acetic acids. J Med Chem (1978) 0.75
Salicylate excretion in the rat; free flow micropuncture experiments. J Pharmacol Exp Ther (1978) 0.75
Comparative pharmacology of uricosuric drugs. Gen Pharmacol (1976) 0.75
(Acylaryloxy)acetic acid diuretics. 3. 2,3-Dihydro-5-acyl-2-benzofurancarboxylic acids, a new class of uricosuric diuretics. J Med Chem (1981) 0.75
Effects of p-aminohippurate and pyrazinoate on urate excretion in Cebus monkeys. J Pharmacol Exp Ther (1984) 0.75
Mechanisms of drug absorption and excretion. The renal excretion of drugs and related compounds. Annu Rev Pharmacol (1967) 0.75
Renal effects of uricosuric agents in the Cebus monkey. J Pharmacol Exp Ther (1970) 0.75
Bidirectional renal urate transport in the chimpanzee. Effects of drugs on secretory and reabsorptive fluxes. Prog Biochem Pharmacol (1974) 0.75
The renal handling of zoxazolamine (flexin). J Pharmacol Exp Ther (1968) 0.75
Uricosuric agents. Arthritis Rheum (1976) 0.75
Proper use of new diuretics. Postgrad Med (1970) 0.75
The effects of 2,4,6-triaminopyrimidine (TAP) on sodium and potassium excretion by the rat kidney: comparison with amiloride. J Pharmacol Exp Ther (1978) 0.75
A new platelet aggregation inhibitor which possesses hypolipemic and uricosuric properties, 2-[3-(2-thiazolylthio)phenyl]propionic acid (TPA). J Pharmacol Exp Ther (1979) 0.75
Diuretic and antihypertensive effects of 2-aminoethyl-4-(1,1-dimethylethyl)-6-iodophenol hydrochloride (MK-447). J Pharmacol Exp Ther (1979) 0.75
A micropuncture study of urate excretion by Cebus monkeys employing high performance liquid chromatography with amperometric detection of urate. Pflugers Arch (1980) 0.75
The biotransformation of (6,7-dichloro-2-methyl-1-oxo-2-phenyl-5-indanyloxy) acetic acid (MK-196) in the chimpanzee. Drug Metab Dispos (1977) 0.75
Renal urate excretion in animal models. Nephron (1975) 0.75
Studies of the fate of metabolites and analogs of probenecid. The significance of metabolic sites, especially lack of ring hydroxylation. Drug Metab Dispos (1975) 0.75
Species variations among primates in responses to drugs which alter the renal excretion of uric acid. J Pharmacol Exp Ther (1975) 0.75
Urate excretion: drug interactions. J Pharmacol Exp Ther (1979) 0.75
Inhibition of urate excretion by pyrazinoate: a micropuncture study. Am J Physiol (1975) 0.75
Enantiomers of indacrinone: a new approach to producing an isouricemic diuretic. Clin Exp Hypertens A (1982) 0.75
Kinetic constants for urate transport. Am J Physiol (1982) 0.75