Published in Science on September 14, 1979
Sequential chemotherapy with methotrexate and 5-fluorouracil for chemotherapy-naive advanced gastric cancer with disseminated intravascular coagulation at initial diagnosis. J Cancer Res Clin Oncol (2010) 0.88
DNA fragmentation, dATP pool elevation and potentiation of antifolate cytotoxicity in L1210 cells by hypoxanthine. Br J Cancer (1992) 0.85
5-fluorouracil-methotrexate synergy: enhancement of 5-fluorodeoxyridylate binding to thymidylate synthase by dihydropteroylpolyglutamates. Proc Natl Acad Sci U S A (1980) 0.85
Red blood cell hypoxanthine phosphoribosyltransferase activity measured using 6-mercaptopurine as a substrate: a population study in children with acute lymphoblastic leukaemia. Br J Clin Pharmacol (1993) 0.85
Chemotherapy for gastric cancer. Gut (1992) 0.81
Schedule-dependent cytotoxicity of methotrexate and 5-fluorouracil in human colon and breast tumor cell lines. J Clin Invest (1980) 0.80
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Weekly etoposide, epirubicin, cisplatin, 5-fluorouracil and leucovorin: an effective chemotherapy in advanced gastric cancer. Br J Cancer (1998) 0.77
Anticancer conjugates and cocktails based on methotrexate and nucleoside synergism. Clin Med Oncol (2009) 0.76
A phase II study of combined chemotherapy with methotrexate, 5-fluorouracil, and low-dose cisplatin (MFP) for histologically diffuse-type advanced and recurrent gastric cancer (KDOG9501). Gastric Cancer (2006) 0.76
Schedule-selective biochemical modulation of 5-fluorouracil in advanced colorectal cancer--a phase II study. BMC Cancer (2002) 0.75
The design of rational combination chemotherapy for cancer. West J Med (1984) 0.75
Sensitization to low dose 5-fluorouracil. Subsequent enhancement of its systemic antitumor effect in the rat. J Clin Invest (1982) 0.75
Experimental Studies in Nerve Transplants. Ann Surg (1934) 10.28
Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus. N Engl J Med (1992) 7.40
THE SURGICAL PROBLEM OF HYPERTENSION. Ann Surg (1938) 3.28
Progress report of combined chemoradiotherapy versus radiotherapy alone in patients with esophageal cancer: an intergroup study. J Clin Oncol (1997) 2.73
POTASSIUM TELLURITE AS AN INDICATOR OF MICROBIAL LIFE. Am J Public Health (N Y) (1914) 2.55
PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer. Proc Natl Acad Sci U S A (2000) 2.17
Transportation of prion protein across the intestinal mucosa of scrapie-susceptible and scrapie-resistant sheep. J Pathol (2006) 2.10
SPONGIOBLASTOMA MULTIFORME OF THE BRAIN. Ann Surg (1928) 2.10
PPARalpha agonist fenofibrate improves diabetic nephropathy in db/db mice. Kidney Int (2006) 2.05
HIV incidence among needle exchange participants: estimates from syringe tracking and testing data. J Acquir Immune Defic Syndr (1994) 1.84
Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in human transitional bladder cancer and its role in inducing cell death. Neoplasia (1999) 1.78
Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation. Neuroscience (2007) 1.76
HIV-1 transmission in injection paraphernalia: heating drug solutions may inactivate HIV-1. J Acquir Immune Defic Syndr (1999) 1.72
A model-based estimate of HIV infectivity via needle sharing. J Acquir Immune Defic Syndr (1992) 1.65
Comparison of patient self-reports and urinalysis results obtained under naturalistic methadone treatment conditions. Drug Alcohol Depend (2000) 1.62
Evidence that hospital hygiene is important in the control of methicillin-resistant Staphylococcus aureus. J Hosp Infect (2001) 1.58
A circulation theory of needle exchange. AIDS (1994) 1.58
CELLULAR ORIGIN OF RHEUMATOID FACTOR. J Exp Med (1959) 1.55
CLINICAL AND EXPERIMENTAL EXPERIENCES IN THE SURGICAL TREATMENT OF HYPERTENSION. Ann Surg (1939) 1.54
HIV prevalence among intravenous drug users: model-based estimates from New Haven's legal needle exchange. J Acquir Immune Defic Syndr (1992) 1.51
Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans. Am J Physiol (1997) 1.46
A decline in HIV-infected needles returned to New Haven's needle exchange program: client shift or needle exchange? Am J Public Health (1994) 1.45
Cytoplasmic sequestration of rel proteins by IkappaBalpha requires CRM1-dependent nuclear export. Mol Cell Biol (2000) 1.44
Ankyrin-B is required for intracellular sorting of structurally diverse Ca2+ homeostasis proteins. J Cell Biol (1999) 1.44
On the distribution of rheumatoid factors among the immunoglobulins. Immunochemistry (1966) 1.41
Application of the 3M microvascular anastomotic device in non-vascular tubular structures. J Reconstr Microsurg (1994) 1.39
Comparison of student outcomes and preferences in a traditional vs. World Wide Web-based baccalaureate nursing research course. J Nurs Educ (2000) 1.39
Mivacurium and prolonged neuromuscular block. Br J Anaesth (1995) 1.39
Cardiac hypertrophy in chronically anemic fetal sheep: Increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia-inducible factor 1. Am J Obstet Gynecol (1998) 1.38
Products of the peptic digestion of human gamma-G-immunoglobulin. Biochemistry (1967) 1.36
Phase I/II trial of accelerated fractionation in brain metastases RTOG 85-28. Int J Radiat Oncol Biol Phys (1993) 1.30
The social geography of AIDS and hepatitis risk: qualitative approaches for assessing local differences in sterile-syringe access among injection drug users. Am J Public Health (2000) 1.30
Signals involved in T cell activation. II. Distinct roles of intact accessory cells, phorbol esters, and interleukin 1 in activation and cell cycle progression of resting T lymphocytes. J Immunol (1986) 1.27
Survival of HIV-1 in syringes. J Acquir Immune Defic Syndr Hum Retrovirol (1999) 1.27
Surveillance of work-related asthma in selected U.S. states using surveillance guidelines for state health departments--California, Massachusetts, Michigan, and New Jersey, 1993-1995. MMWR CDC Surveill Summ (1999) 1.27
Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine. J Pharmacol Exp Ther (1996) 1.22
Supplementary enteral nutrition maintains remission in paediatric Crohn's disease. Gut (1996) 1.22
Stable long-term recordings from cat peripheral nerves. Brain Res (1977) 1.21
Altered expression of chondroitin sulfate proteoglycan in the stroma of human colon carcinoma. Hypomethylation of PG-40 gene correlates with increased PG-40 content and mRNA levels. J Biol Chem (1990) 1.20
Analysis of neutron radiotherapy treatment complications. Bull Cancer (1986) 1.20
Expression of the TAL1 proto-oncogene in cultured endothelial cells and blood vessels of the spleen. Oncogene (1993) 1.19
Prostaglandin E2 inhibits renal collecting duct Na+ absorption by activating the EP1 receptor. J Clin Invest (1998) 1.16
Human granulocytic ehrlichiosis during pregnancy treated successfully with rifampin. Clin Infect Dis (1998) 1.14
A simple method for the synthesis of tetrahydrofolic acid. Anal Biochem (1968) 1.13
Interactive effects of depression symptoms, nicotine dependence, and weight change on late smoking relapse. J Consult Clin Psychol (1996) 1.12
Detection by polymerase chain reaction of human immunodeficiency virus type 1 proviral DNA sequences in needles of injecting drug users. J Infect Dis (1992) 1.12
Enhanced expression of cyclooxygenase-2 in high grade human transitional cell bladder carcinomas. Am J Pathol (2000) 1.12
An analysis of 1539 patients with cancer of unknown primary site. Cancer (1986) 1.11
Characterization of ocular surface symptoms from optometric practices in North America. Cornea (2001) 1.10
Prevalence and characteristics of Staphylococcus aureus in Connecticut swine and swine farmers. Zoonoses Public Health (2012) 1.10
Intramembranous absorption rate is unaffected by changes in amniotic fluid composition. Am J Physiol Renal Physiol (2005) 1.10
Factors determining the susceptibility of NIH swiss mice to erythroleukemia induced by Friend murine leukemia virus. Virology (1982) 1.10
Determination of protein by a modified Lowry procedure in the presence of some commonly used detergents. Anal Biochem (1979) 1.09
The oxidation of dithiothreitol by peroxidases and oxygen. Biochim Biophys Acta (1976) 1.09
Nicotine patch and self-help video for cigarette smoking cessation. J Consult Clin Psychol (1997) 1.09
Cloning, expression, and regulation of rabbit cyclooxygenase-2 in renal medullary interstitial cells. Am J Physiol (1997) 1.09
Properties of extracellular neuraminidase produced by group A streptococcus. Infect Immun (1979) 1.09
The Results of a Specifically Co-ordinated Plan of Medical and Surgical Treatment of Essential Hypertension. Ann Surg (1948) 1.08
Regulatory response to washout of amniotic fluid in sheep. Am J Physiol Heart Circ Physiol (2004) 1.08
Do heavy smokers benefit from higher dose nicotine patch therapy? Exp Clin Psychopharmacol (1999) 1.08
Alterations in lipoxygenase and cyclooxygenase-2 catalytic activity and mRNA expression in prostate carcinoma. Neoplasia (2001) 1.08
HIV incidence among New Haven needle exchange participants: updated estimates from syringe tracking and testing data. J Acquir Immune Defic Syndr Hum Retrovirol (1995) 1.08
Modulation of 5-fluorouracil metabolism and cytotoxicity by antimetabolite pretreatment in human colorectal adenocarcinoma HCT-8. Cancer Res (1981) 1.07
Can HIV-1-contaminated syringes be disinfected? Implications for transmission among injection drug users. J Acquir Immune Defic Syndr (2001) 1.07
Reactivity of human sera to different strains of granulocytic ehrlichiae in immunodiagnostic assays. J Infect Dis (1998) 1.06
Survival of HIV-1 in syringes: effects of temperature during storage. Subst Use Misuse (2000) 1.06
THE RELATION OF THE HYPOPHYSIS, HYPOTHALAMUS, AND THE AUTONOMIC NERVOUS SYSTEM TO CARBOHYDRATE METABOLISM. Ann Surg (1934) 1.04
Diversity in membrane binding sites of ankyrins. Brain ankyrin, erythrocyte ankyrin, and processed erythrocyte ankyrin associate with distinct sites in kidney microsomes. J Biol Chem (1989) 1.04
Validity of a telephone-administered 24-hour dietary recall in telephone and non-telephone households in the rural Lower Mississippi Delta region. J Am Diet Assoc (2001) 1.02
Circulating immune complexes in sera of patients with Burkett's lymphoma and nasopharyngeal carcinoma. Int J Cancer (1976) 1.02
An SH3 domain is required for the mitogenic activity of microinjected phospholipase C-gamma 1. FEBS Lett (1995) 1.02
Inhibition of complement fixation by rheumatoid sera. Ann N Y Acad Sci (1965) 1.02
HIV DNA and antibodies in syringes from injecting drug users: a comparison of detection techniques. AIDS (1993) 1.01
Endemic Serratia marcescens in the Veterans Administration Hospital in Pittsburgh, Pa., 1971--1976. Health Lab Sci (1978) 1.01
Detection of HIV-1 nucleic acid and HIV-1 antibodies in needles and syringes used for non-intravenous injection. AIDS (1998) 1.01
Peroxisome proliferator-activated receptor-gamma activity is associated with renal microvasculature. Am J Physiol Renal Physiol (2001) 1.01
Survival of women with metastatic breast cancer at Yale from 1920 to 1980. J Clin Oncol (1983) 1.00
Minority use of community long-term care services: a comparative analysis. J Gerontol B Psychol Sci Soc Sci (1996) 1.00
Radiation therapy as a treatment for benign lymphoepithelial parotid cysts in patients infected with human immunodeficiency virus-1. Int J Radiat Oncol Biol Phys (1992) 0.99
Genetic defect responsible for the dysfunctional protein: factor IXLong Beach. Blood (1988) 0.99
SOME IMPORTANT FACTORS IN THE PREPARATION OF CULTURE MEDIA. Am J Public Health (N Y) (1920) 0.99
Immunoglobulins of sheep. Arch Biochem Biophys (1969) 0.98
Geographic differences in mortality from stroke in North Caroline. 1. Analysis of death certificates. Stroke (1976) 0.98
Differential localization of prostaglandin E receptor subtypes in human kidney. Am J Physiol (1996) 0.98
The influence of methotrexate pretreatment on 5-fluorouracil metabolism in L1210 cells. J Biol Chem (1981) 0.97
GDF-5 deficiency in mice leads to disruption of tail tendon form and function. Connect Tissue Res (2001) 0.97
IgM and IgG anti-F(ab')2 antibodies in rheumatoid arthritis and systemic lupus erythematosus. Arthritis Rheum (1982) 0.97
Principles underlying new methods for chronic neural recording. Can J Neurol Sci (1975) 0.96
Race, finding meaning, and caregiver distress. J Aging Health (1997) 0.96
'Dropouts' or 'drop-ins'? Client retention and participation in New Haven's needle exchange program. Public Health Rep (1995) 0.95
Regulation of human T lymphocyte mitogenesis by antibodies to CD3. J Immunol (1986) 0.95
Veterans Administration cooperative study on aphasia: a comparison of individual and group treatment. J Speech Hear Res (1981) 0.95
Yeast meiotic mutants proficient for the induction of ectopic recombination. Genetics (1998) 0.94
Allelic loss on chromosome 6Q in primary prostate cancer. Int J Cancer (1999) 0.94
Repetition in the transcortical aphasias. Brain Lang (1978) 0.94
A phase II trial of gefitinib with 5-fluorouracil, leucovorin, and irinotecan in patients with colorectal cancer. Br J Cancer (2005) 0.94
The subunit structure of the fructose diphosphate aldolase from spinach leaf. Arch Biochem Biophys (1969) 0.94
Clinical value of mammography for symptomatic women 35 years of age and younger. Am J Obstet Gynecol (1999) 0.93