Published in Br J Pharmacol on July 01, 1969
Spasmolytic effects of cadmium and zinc ions upon the guinea-pig isolated ileum preparation. Br J Pharmacol (1971) 0.85
Mechanism of cadmium-induced contraction in ileal longitudinal muscle of guinea-pig. Br J Pharmacol (1982) 0.75
Spontaneous subthreshold activity at motor nerve endings. J Physiol (1952) 42.17
Acetylcholine release in the cat's superior cervical ganglion. J Physiol (1953) 16.74
The ionic requirements for the production of action potentials in crustacean muscle fibres. J Physiol (1958) 13.87
The action of morphine and related substances on contraction and on acetylcholine output of coaxially stimulated guinea-pig ileum. Br J Pharmacol Chemother (1957) 13.02
The action of botulinum toxin on the neuro-muscular junction. J Physiol (1949) 12.25
Interaction of drugs and the effect of cooling on the isolated mammalian intestine. J Physiol (1946) 9.62
The origin of acetylcholine released from guinea-pig intestine and longitudinal muscle strips. J Physiol (1968) 9.44
Drugs which antagonize 5-hydroxytryptamine. Br J Pharmacol Chemother (1954) 7.90
THE INITIATION OF SPIKE POTENTIAL IN BARNACLE MUSCLE FIBERS UNDER LOW INTRACELLULAR CA++. J Gen Physiol (1964) 7.81
The peripheral action of Cl. botulinum toxin. J Physiol (1949) 7.80
Two kinds of tryptamine receptor. Br J Pharmacol Chemother (1957) 7.63
Tetrodotoxin, saxitoxin and their significance in the study of excitation phenomena. Pharmacol Rev (1966) 7.45
Tetrodotoxin and neuromuscular transmission. Proc R Soc Lond B Biol Sci (1967) 6.14
Classification of intestinomotor drugs by means of type D botulinum toxin. J Physiol (1955) 4.11
Effects of tetrodotoxin on innervated smooth muscle preparations. Br J Pharmacol Chemother (1967) 3.59
Inhibition by morphine of the release of acetylcholine from the intestine of the guinea-pig. Br J Pharmacol Chemother (1957) 3.52
Return of cholinesterase activity in the rat after inhibition by organophosphorus compounds. I. Diethyl p-nitro-phenyl phosphate (E 600, paraoxon). Biochem J (1953) 3.12
LOCALIZATION OF CHOLINE ESTERASE IN NERVE FIBERS. Science (1940) 3.05
The effects of lowering the bath temperature on the responses of the isolated guinea-pig ileum. J Physiol (1957) 2.50
THE ORIGIN OF THE ACETYLCHOLINE RELEASED SPONTANEOUSLY FROM THE GUINEA-PIG ISOLATED ILEUM. Br J Pharmacol Chemother (1963) 2.37
THE SITE OF THE 5-HYDROXYTRYPTAMINE RECEPTOR ON THE INTRAMURAL NERVOUS PLEXUS OF THE GUINEA-PIG ISOLATED ILEUM. Br J Pharmacol Chemother (1963) 2.36
CHOLINERGIC TRANSMISSION AND ACETYLCHOLINE OUTPUT. Can J Biochem Physiol (1963) 2.26
Assay of acetylcholine on the rat blood pressure. J Pharm Pharmacol (1958) 2.02
Effect of cooling, local anaesthetic compounds and botulinum toxin on the responses of and the acetylcholine output from the electrically transmurally stimulated isolated guinea-pig ileum. Br J Pharmacol Chemother (1962) 1.91
Inhibition of the release of acetylcholine from isolated guinea-pig ileum by crystalline tetrodotoxin. J Pharmacol Exp Ther (1966) 1.55
Tetrodotoxin and manganese ions: effects on electrical activity and tension in taenia coli of guinea pig. Science (1966) 1.50
THE MODE OF ACTION OF NEOSTIGMINE AND PHYSOSTIGMINE ON THE GUINEA-PIG TRACHEALIS MUSCLE. Br J Pharmacol Chemother (1963) 1.44
The inhibitory action of morphine on the contraction of the longitudinal muscle coat of the isolated guinea-pig ileum. Br J Pharmacol Chemother (1958) 1.36
Actions of calcium and certain multivalent cations on potassium contracture of guinea-pig's taenia coli. J Physiol (1967) 1.25
An evaluation of the action of substance P on the jejunum of the rabbit. J Pharmacol Exp Ther (1956) 1.25
The effects of Ba2+ and Mn2+ on the smooth muscle of guinea-pig taenia coli. J Physiol (1968) 0.99
[The effect of some histamine-chelating heavy metals on the histamine contraction of the guinea pig ileum]. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol (1966) 0.86
K+ is an endothelium-derived hyperpolarizing factor in rat arteries. Nature (1998) 6.29
Comparison of the effects of BRL 34915 and verapamil on electrical and mechanical activity in rat portal vein. Br J Pharmacol (1986) 4.75
The effects of BRL 34915 and nicorandil on electrical and mechanical activity and on 86Rb efflux in rat blood vessels. Br J Pharmacol (1986) 3.68
Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels. Br J Pharmacol (1988) 3.66
Effect of apamin on responses to BRL 34915, nicorandil and other relaxants in the guinea-pig taenia caeci. Br J Pharmacol (1986) 2.89
Evidence that the spasmogenic action of tetraethylammonium in guinea-pig trachealis is both direct and dependent on the cellular influx of calcium ion. Br J Pharmacol (1983) 2.84
Endothelium-derived hyperpolarizing factor: a new endogenous inhibitor from the vascular endothelium. Trends Pharmacol Sci (1988) 2.79
The pharmacology of ATP-sensitive potassium channels. Annu Rev Pharmacol Toxicol (1993) 2.64
Some effects of sodium nitroprusside, methoxyverapamil (D600) and nifedipine on rat portal vein. Br J Pharmacol (1980) 2.52
Simultaneous long-term recording of the mechanical and intracellular electrical activity of smooth muscles. J Pharmacol Methods (1980) 2.37
Initiation and evaluation of a pilot scheme for minor surgery in general practice. Health Trends (1990) 1.96
Characterization of an apamin-sensitive small-conductance Ca(2+)-activated K(+) channel in porcine coronary artery endothelium: relevance to EDHF. Br J Pharmacol (2002) 1.94
Ion channel modulation by NS 1619, the putative BKCa channel opener, in vascular smooth muscle. Br J Pharmacol (1994) 1.60
Further investigation of endothelium-derived hyperpolarizing factor (EDHF) in rat hepatic artery: studies using 1-EBIO and ouabain. Br J Pharmacol (1999) 1.55
KATP--fact or artefact? New thoughts on the mode of action of the potassium channel openers. Cardiovasc Res (1994) 1.54
Role of gap junctions in the responses to EDHF in rat and guinea-pig small arteries. Br J Pharmacol (1999) 1.53
Endothelium-dependent effects of acetylcholine in rat aorta: a comparison with sodium nitroprusside and cromakalim. Br J Pharmacol (1988) 1.51
Characterization of potassium currents modulated by BRL 38227 in rat portal vein. Br J Pharmacol (1992) 1.50
The relaxant action of BRL 34915 in rat uterus. Br J Pharmacol (1987) 1.45
Evidence that the mechanism of the inhibitory action of pinacidil in rat and guinea-pig smooth muscle differs from that of glyceryl trinitrate. Br J Pharmacol (1987) 1.41
Has pharmacology a place in today's medical schools. Br J Clin Pharmacol (1976) 1.39
Effects of methyl beta-cyclodextrin on EDHF responses in pig and rat arteries; association between SK(Ca) channels and caveolin-rich domains. Br J Pharmacol (2007) 1.39
A comparison of several calcium antagonists on uterine, vascular and cardiac muscles from the rat. Br J Pharmacol (1985) 1.38
Endothelium-derived hyperpolarizing factor--a critical appraisal. Prog Drug Res (1998) 1.35
Levcromakalim may induce a voltage-independent K-current in rat portal veins by modifying the gating properties of the delayed rectifier. Br J Pharmacol (1993) 1.33
Some features of the spasmogenic actions of acetylcholine and histamine in guinea-pig isolated trachealis. Br J Pharmacol (1984) 1.33
Cromakalim, nicorandil and pinacidil: novel drugs which open potassium channels in smooth muscle. Gen Pharmacol (1989) 1.31
The spasmogenic action of potassium chloride in guinea-pig trachealis. Br J Pharmacol (1983) 1.31
Characteristics of cromakalim-induced relaxations in the smooth muscle cells of guinea-pig mesenteric artery and vein. Br J Pharmacol (1988) 1.30
Actions of cromakalim on ionic currents recorded from single smooth muscle cells of the rat portal vein. J Pharmacol Exp Ther (1990) 1.30
Role of gap junctions and EETs in endothelium-dependent hyperpolarization of porcine coronary artery. Br J Pharmacol (2000) 1.30
Functional evidence of a role for two-pore domain potassium channels in rat mesenteric and pulmonary arteries. Br J Pharmacol (2004) 1.29
Differences between the effects of cromakalim and nifedipine on agonist-induced responses in rabbit aorta. Br J Pharmacol (1991) 1.29
Structure-activity relationships of K+ channel openers. Trends Pharmacol Sci (1990) 1.28
Mechanical and electrical aspects of the relaxant action of aminophylline in guinea-pig isolated trachealis. Br J Pharmacol (1986) 1.27
Simultaneous recording of electrical and mechanical activity from intestinal and vascular smooth muscle [proceedings]. Br J Pharmacol (1977) 1.27
The action of diazoxide and minoxidil sulphate on rat blood vessels: a comparison with cromakalim. Br J Pharmacol (1990) 1.26
Influence of the vascular endothelium on agonist-induced contractions and relaxations in rat aorta. Br J Pharmacol (1986) 1.26
Involvement of voltage-dependent potassium channels in the EDHF-mediated relaxation of rat hepatic artery. Br J Pharmacol (1997) 1.24
Nerve-mediated inhibition of mechanical activity in rabbit duodenum and the effects of desensitization to adenosine and several of its derivatives. Br J Pharmacol (1973) 1.21
Theophylline antagonizes some effects of purines in the intestine but not those of intramural inhibitory nerve stimulation. Br J Pharmacol (1979) 1.20
Studies on the effects of anandamide in rat hepatic artery. Br J Pharmacol (1997) 1.19
Suppression of K(+)-induced hyperpolarization by phenylephrine in rat mesenteric artery: relevance to studies of endothelium-derived hyperpolarizing factor. Br J Pharmacol (2001) 1.17
The potassium channel opening action of pinacidil; studies using biochemical, ion flux and microelectrode techniques. Naunyn Schmiedebergs Arch Pharmacol (1988) 1.15
The effects of isoprenaline and phenylephrine on oxygen consumption in isolated smooth muscle. Br J Pharmacol (1972) 1.14
Potassium channel modulation in rat portal vein by ATP depletion: a comparison with the effects of levcromakalim (BRL 38227). Br J Pharmacol (1992) 1.14
Potassium channel openers and vascular smooth muscle relaxation. Pharmacol Ther (1990) 1.13
Effects of isoprenaline and phenylephrine on energy-rich phosphate compounds and glucose-6-phosphate in smooth and cardiac muscle. Br J Pharmacol (1971) 1.13
Effects of P1060 and aprikalim on whole-cell currents in rat portal vein; inhibition by glibenclamide and phentolamine. Br J Pharmacol (1993) 1.10
Behavioural changes following olfactory bulbectomy in rats: a possible model for the detection of antidepressant drugs [proceedings]. Br J Pharmacol (1976) 1.08
Effects of cytochrome P450 inhibitors on EDHF-mediated relaxation in the rat hepatic artery. Br J Pharmacol (1996) 1.08
The spontaneous electrical and mechanical activity of the longitudinal smooth muscle of the rabbit duodenum and its modification by drugs and temperature changes. J Pharm Pharmacol (1971) 1.04
Effects of calcium entry blockers on tension development and calcium influx in rat uterus. Br J Pharmacol (1986) 1.02
Inhibition of the longitudinal muscle of rabbit duodenum. Br J Pharmacol (1971) 1.02
Role of endothelial cell hyperpolarization in EDHF-mediated responses in the guinea-pig carotid artery. Br J Pharmacol (2000) 1.02
The involvement of potassium channels in the action of ciclazindol in rat portal vein. Br J Pharmacol (1992) 1.01
Induction of a glibenclamide-sensitive K-current by modification of a delayed rectifier channel in rat portal vein in insulinoma cells. Br J Pharmacol (1993) 1.01
The spasmogenic action of oxytocin in the rat uterus--comparison with other agonists. Br J Pharmacol (1986) 1.00
Olfactory bulb ablation in the rat: behavioural changes and their reversal by antidepressant drugs. Br J Pharmacol (1977) 0.98
EDHF -- are there gaps in the pathway? J Physiol (2001) 0.98
Effect of adrenaline, noradrenaline, atropine, and nicotine on some types of human tremor. J Neurol Neurosurg Psychiatry (1966) 0.96
Letter: Salbutamol and inhibition of uterine contractions. J Pharm Pharmacol (1973) 0.95
Effects of cytochrome P450 inhibitors on potassium currents and mechanical activity in rat portal vein. Br J Pharmacol (1996) 0.94
The accumulation of adenosine in rabbit intestinal muscle. Br J Pharmacol (1974) 0.94
Comparison of the effects of several potassium-channel openers on rat bladder and rat portal vein in vitro. Br J Pharmacol (1991) 0.94
The contribution of Rb-permeable potassium channels to the relaxant and membrane hyperpolarizing actions of cromakalim, RP49356 and diazoxide in bovine tracheal smooth muscle. Br J Pharmacol (1991) 0.94
Some effects of D600, nifedipine and sodium nitroprusside on electrical and mechanical activity in rat portal vein [proceedings]. Br J Pharmacol (1976) 0.93
Pharmacology of the potassium channel openers. Cardiovasc Drugs Ther (1995) 0.93
Further investigations into the endothelium-dependent hyperpolarizing effects of bradykinin and substance P in porcine coronary artery. Br J Pharmacol (2001) 0.93
Some effects of dipyridamole, hexobendine and lidoflazine on inhibitory processes in rabbit duodenum. Br J Pharmacol (1974) 0.91
Effects of the antiemetic drug domperidone on guinea-pig isolated gastrointestinal tissue [proceedings]. J Pharm Pharmacol (1978) 0.90
Investigation of the effects of 5-nitro-2-(3-phenylpropylamino)-benzoic acid (NPPB) on membrane currents in rat portal vein. Br J Pharmacol (1996) 0.89
Intermediate-conductance calcium-activated potassium channels participate in neurovascular coupling. Br J Pharmacol (2011) 0.89
Antagonism of levcromakalim by imidazoline- and guanidine-derivatives in rat portal vein: involvement of the delayed rectifier. Br J Pharmacol (1993) 0.88
Quantitative assessment of climbing behaviour in mice [proceedings]. Br J Pharmacol (1977) 0.88
Pharmacological validation of a new test for the detection of antidepressant activity of drugs [proceedings]. Br J Pharmacol (1977) 0.88
The economics of mild hypertension programmes. Soc Sci Med (1989) 0.88
Analysis of the depressant effect of the endothelium on contractions of rabbit isolated basilar artery to 5-hydroxytryptamine. Br J Pharmacol (1992) 0.87
3-Morpholinosydnonimine (SIN-1) and K(+) channels in smooth muscle cells of the rabbit and guinea pig carotid arteries. Eur J Pharmacol (2000) 0.86
Spasmolytic effects of cadmium and zinc ions upon the guinea-pig isolated ileum preparation. Br J Pharmacol (1971) 0.85
Effects of cromakalim, RP49356, diazoxide, glibenclamide and galanin in rat portal vein. Eur J Pharmacol (1990) 0.84
The effect of desensitization to adenosine triphosphate on the peristaltic reflex in guinea-pig ileum. Br J Pharmacol (1973) 0.84
Theophylline is not an antagonist of intramural inhibitory nerve activity in rabbit and guinea pig intestine [proceedings]. Br J Pharmacol (1979) 0.84
Effects of rubidium on responses to potassium channel openers in rat isolated aorta. Br J Pharmacol (1993) 0.84
Characterization of receptors on postganglionic cholinergic neurons in the guinea-pig isolated ileum. J Pharm Pharmacol (1979) 0.83
Changes in the amounts of high-energy phosphate compounds associated with the actions of phenylephrine and isoprenaline on smooth and cardiac muscle. Br J Pharmacol (1970) 0.83
Comparison of the excitatory and inhibitory effects of angiotensin and vasopressin on mammalian portal vein. Blood Vessels (1976) 0.83
Levamisole--a general pharmacological perspective. Int J Immunopharmacol (1981) 0.82
Differential effects of prostacyclin and iloprost in the isolated carotid artery of the guinea-pig. Eur J Pharmacol (2001) 0.81
Effects of BRL55834 in rat portal vein and bovine trachea: evidence for the induction of a glibenclamide-resistant, ATP-sensitive potassium current. Br J Pharmacol (1995) 0.81
Levcromakalim-induced modulation of membrane potassium currents, intracellular calcium and mechanical activity in rat mesenteric artery. Naunyn Schmiedebergs Arch Pharmacol (1994) 0.81
The adrenoceptors mediating catecholamine effects in frog isolated skin. J Pharm Pharmacol (1973) 0.81
Potassium channel openers. Pharmacological effects and future uses. Drugs (1990) 0.80
Pharmacological characterization of the inwardly-rectifying current in the smooth muscle cells of the rat bladder. Br J Pharmacol (1996) 0.80
The application of irritant chemicals selectively to the skin of the leech ganglion/body wall preparation. J Pharmacol Methods (1984) 0.80
Recent advances in potassium channel modulation. Prog Drug Res (1997) 0.80
A comparison of the actions of cromakalim and nifedipine on rabbit isolated mesenteric artery. Eur J Pharmacol (1990) 0.80
Modulation of membrane currents and mechanical activity by niflumic acid in rat vascular smooth muscle. Eur J Pharmacol (1996) 0.80
Pharmacology of reproduction and fertility. Annu Rev Pharmacol (1968) 0.80
The effect of psychoactive drugs on plasma corticosterone levels and behavioural in the bulbectomised rat. Pharmacol Biochem Behav (1979) 0.80