Published in Lancet on December 20, 1975
Smooth muscle autoantibodies and autoantigens. Clin Exp Immunol (1979) 1.42
Immunofluorescence studies on autoantibodies to steroid-producing cells, and to germline cells in endocrine disease and infertility. Clin Exp Immunol (1980) 1.32
Subclinical coeliac disease and infertility. Br Med J (1976) 0.93
Antigenicity of janin, a new protein from smooth muscle. Clin Exp Immunol (1976) 0.79
Effect of general practitioners' advice against smoking. Br Med J (1979) 24.07
THE NATURE OF THE PERIPHERAL RESISTANCE IN ARTERIAL HYPERTENSION WITH SPECIAL REFERENCE TO THE VASOMOTOR SYSTEM. J Clin Invest (1936) 18.94
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol (2000) 16.83
Intercapillary Lesions in the Glomeruli of the Kidney. Am J Pathol (1936) 12.50
Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med (1999) 11.27
A plethysmographic method for measuring systolic blood pressure in the intact rat. J Physiol (1938) 7.20
Rethinking sexual health clinics. BMJ (1995) 7.03
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nat Genet (2001) 6.92
Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus. J Virol (1991) 6.19
Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutants. J Virol (1984) 5.89
P-element-mediated enhancer detection: a versatile method to study development in Drosophila. Genes Dev (1989) 5.76
Prospective screening of dyspeptic patients by Helicobacter pylori serology. Lancet (1995) 5.02
Benign and Malignant Hypertension and Nephrosclerosis: A Clinical and Pathological Study. Am J Pathol (1936) 4.43
Genetic evidence for the spread of agriculture in Europe by demic diffusion. Nature (1991) 4.34
A cytogenetic study of 1000 spontaneous abortions. Ann Hum Genet (1980) 3.82
Atypical beta-adrenoceptor on brown adipocytes as target for anti-obesity drugs. Nature (1984) 3.64
Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum. Proc Natl Acad Sci U S A (1997) 3.61
Inflammatory Lesions in the Glomeruli in Pyelonephritis in Relation to Hypertension and Renal Insufficiency. Am J Pathol (1936) 3.52
Mutation of a tyrosine localization signal in the cytosolic tail of yeast Kex2 protease disrupts Golgi retention and results in default transport to the vacuole. Mol Biol Cell (1992) 3.49
New world views: preparing physicians in training for global health work. Fam Med (2000) 3.23
A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila. Genes Dev (1996) 3.21
Evidence for specificity in the encapsidation of Sindbis virus RNAs. J Virol (1989) 2.91
Generation of a neutralization-resistant variant of HIV-1 is due to selection for a point mutation in the envelope gene. Cell (1988) 2.91
Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway. Genes Dev (1999) 2.87
Plasma nicotine levels after smoking cigarettes with high, medium, and low nicotine yields. Br Med J (1975) 2.80
Structure of the CAP-DNA complex at 2.5 angstroms resolution: a complete picture of the protein-DNA interface. J Mol Biol (1996) 2.80
Hyperglobulinaemia in liver disease. Lancet (1973) 2.74
Bird-fancier's lung and jejunal villous atrophy. Lancet (1975) 2.71
Amoebiasis-a diagnostic problem in Great Britain. Br Med J (1966) 2.70
Australia antigen in acute and chronic liver disease. Lancet (1969) 2.65
Comparison of effect on tobacco consumption and carbon monoxide absorption of changing to high and low nicotine cigarettes. Br Med J (1973) 2.65
RNA secondary structure prediction based on free energy and phylogenetic analysis. J Mol Biol (1999) 2.65
Community treatment of end-stage renal failure by dialysis and renal transplantation from cadaver donors. Lancet (1969) 2.53
A cell cycle-regulated bacterial DNA methyltransferase is essential for viability. Proc Natl Acad Sci U S A (1996) 2.52
Bacterial and dietary antibodies in liver disease. Lancet (1972) 2.48
Autoantibodies to reticulin in patients with idiopathic steatorrhoea, coeliac disease, and Crohn's disease, and their relation to immunoglobulins and dietary antibodies. Lancet (1971) 2.45
The general-practitioner obstetrician--the evolution of his role in the next decade. J R Coll Gen Pract (1975) 2.43
Effect of nicotine chewing gum on smoking behaviour and as an aid to cigarette withdrawal. Br Med J (1976) 2.41
A comparison of oral milrinone, digoxin, and their combination in the treatment of patients with chronic heart failure. N Engl J Med (1989) 2.40
DiOC6 staining reveals organelle structure and dynamics in living yeast cells. Cell Motil Cytoskeleton (1993) 2.39
Clinical assessment of a low-oestrogen combined oral contraceptive. Br Med J (1973) 2.32
A computer-derived protocol to aid in the diagnosis of emergency room patients with acute chest pain. N Engl J Med (1982) 2.28
Mobile coronary care and community mortality from myocardial infarction. Lancet (1985) 2.27
Auto-immune reactions in ulcerative colitis. Gut (1966) 2.26
Opioid users' attitudes towards and use of NHS clinics, general practitioners and private doctors. Br J Addict (1986) 2.18
Stimulation and suppression of PCR-mediated recombination. Nucleic Acids Res (1998) 2.17
Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: comparisons between immunocompetent and immunodeficient inbred strains. Gene Ther (1995) 2.11
A microtest for the quantitation of rabies virus neutralizing antibodies. J Biol Stand (1979) 2.10
The treatment and prevention of obesity: a systematic review of the literature. Int J Obes Relat Metab Disord (1997) 2.10
Improving the detection rate of early gastric cancer requires more than open access gastroscopy: a five year study. Gut (1997) 2.09
On the scale of global demographic convergence, 1950-2000. Popul Dev Rev (2001) 2.07
Randomized comparison of enoxaparin with unfractionated heparin following fibrinolytic therapy for acute myocardial infarction. Eur Heart J (2002) 2.06
Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoforms. J Biol Chem (1994) 2.04
Ultrasound simulator for venous access. Emerg Med J (2008) 2.04
Resilience and resistance of a lake phosphorus cycle before and after food web manipulation. Am Nat (1992) 2.01
HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells. Oncogene (2007) 2.00
Antibodies to proteus in rheumatoid arthritis. Lancet (1985) 1.96
Therapeutic Trial of Methionine in Infective Hepatitis. Br Med J (1945) 1.95
Acute chest pain in the emergency room. Identification and examination of low-risk patients. Arch Intern Med (1985) 1.86
The rat lipolytic beta-adrenoceptor: studies using novel beta-adrenoceptor agonists. Eur J Pharmacol (1984) 1.85
UV-Stimulated K Efflux from Rose Cells: Counterion and Inhibitor Studies. Plant Physiol (1982) 1.85
Comparison of increases in carboxyhaemoglobin after smoking "extra-mild" and "non-mild" cigarettes. Lancet (1973) 1.84
Perturbation of Chara Plasmalemma Transport Function by 2[4(2',4'-Dichlorophenoxy)phenoxy]propionic Acid. Plant Physiol (1984) 1.83
Bottle feeding, early gastroenteritis, and inflammatory bowel disease. Br Med J (1979) 1.83
Variability of the lytic susceptibility of Neisseria gonorrhoeae to human sera. J Immunol (1977) 1.81
When immigrants are not migrants: counting arrivals of the foreign born using the U.S. census. Int Migr Rev (1998) 1.80
Persistent measles virus genome in autoimmune chronic active hepatitis. Lancet (1987) 1.79
Idiopathic granulomatous mastitis. A report of three cases and review of the literature. Arch Pathol Lab Med (1994) 1.79
The Brucella abortus CcrM DNA methyltransferase is essential for viability, and its overexpression attenuates intracellular replication in murine macrophages. J Bacteriol (2000) 1.75
Tamponade in Dressler's syndrome with immunological studies. Br Med J (1972) 1.72
Potent antiretroviral therapy of primary human immunodeficiency virus type 1 (HIV-1) infection: partial normalization of T lymphocyte subsets and limited reduction of HIV-1 DNA despite clearance of plasma viremia. J Infect Dis (1999) 1.70
Characterization of the humoral immune response to Klebsiella species in inflammatory bowel disease and ankylosing spondylitis. Br J Rheumatol (1998) 1.69
Isolation and characterization of PEP3, a gene required for vacuolar biogenesis in Saccharomyces cerevisiae. Mol Cell Biol (1991) 1.66
GSK3: a SHAGGY frog story. Trends Cell Biol (1996) 1.65
Complementation between Sindbis viral RNAs produces infectious particles with a bipartite genome. Proc Natl Acad Sci U S A (1991) 1.64
Crohn's disease in a husband and wife. Lancet (1978) 1.61
In vivo examination of membrane protein localization and degradation with green fluorescent protein. Proc Natl Acad Sci U S A (1996) 1.59
Increased antibiotic resistance of Neisseria gonorrhoeae in Korea. Antimicrob Agents Chemother (1976) 1.58
Evaluation of chromogenic meticillin-resistant Staphylococcus aureus media: sensitivity versus turnaround time. J Hosp Infect (2012) 1.58
Raised antibody titres to measles and rubella viruses in chronic active hepatitis. Lancet (1972) 1.57
Common BRCA1 variants and susceptibility to breast and ovarian cancer in the general population. Hum Mol Genet (1997) 1.55
Appendicitis in pregnancy: an ongoing diagnostic dilemma. Colorectal Dis (2008) 1.54
Association of dehydroepiandrosterone sulfate, body composition, and physical fitness in independent community-dwelling older men and women. J Am Geriatr Soc (1998) 1.53
The use of a tissue expander as a vaginal stent in vaginal reconstruction. Br J Obstet Gynaecol (1995) 1.53
Co-induction and laryngeal mask insertion. A comparison of thiopentone versus propofol. Anaesthesia (1997) 1.52
Inhibition by glibenclamide of the vasorelaxant action of cromakalim in the rat. Br J Pharmacol (1989) 1.52
UK accident and emergency departments and emergency contraception: what do they think and do? J Accid Emerg Med (1999) 1.51
Disorders of the long head of the biceps tendon. J Shoulder Elbow Surg (2000) 1.50
Luteinizing hormone levels in plasma and urine in women during normal menstrual cycles and in women taking combined contraceptives or chlormadinone acetate. J Endocrinol (1969) 1.50
2.8 A crystal structure of the malachite green aptamer. J Mol Biol (2000) 1.49
Trypsinogen activation peptides assay in the early prediction of severity of acute pancreatitis. Lancet (1990) 1.49
The structural basis for molecular recognition by the vitamin B 12 RNA aptamer. Nat Struct Biol (2000) 1.48
Evaluation of an inflammation-based prognostic score (GPS) in patients with metastatic breast cancer. Br J Cancer (2006) 1.48
Cloning, expression, and alternative splicing of the receptor for anti-Müllerian hormone. Mol Endocrinol (1994) 1.46
Should patients with inflammatory bowel disease smoke? Br Med J (Clin Res Ed) (1984) 1.46
Controlled prospective study of the effect on liver function of multiple exposures to halothane. Lancet (1975) 1.46
Minimal/mild endometriosis and infertility. A review. Br J Obstet Gynaecol (1989) 1.45
Sexual knowledge and attitudes of general practitioners in Wessex. Br Med J (1977) 1.45