Published in J Pharm Sci on March 01, 1976
Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial. Crit Care Med (1994) 2.66
Pharmacokinetics, safety and immunomodulatory effects of human recombinant interleukin-1 receptor antagonist in healthy humans. Cytokine (1992) 1.63
Interleukin-1 receptor blockade improves survival and hemodynamic performance in Escherichia coli septic shock, but fails to alter host responses to sublethal endotoxemia. J Clin Invest (1992) 1.58
Interleukin-1 receptor antagonist decreases bone loss and bone resorption in ovariectomized rats. J Clin Invest (1994) 1.50
Correction of perfusate concentration for sample removal. J Pharm Sci (1982) 1.19
Biliary excretion and pharmacokinetics of ceftriaxone after cholecystectomy. Eur J Clin Pharmacol (1986) 1.12
Intraocular diclofenac and flurbiprofen concentrations in human aqueous humor following topical application. J Ocul Pharmacol (1994) 1.05
Age-associated changes in ceftriaxone pharmacokinetics. Clin Pharmacokinet (1986) 1.04
Crop grouping: a proposal for public aquaculture. Vet Hum Toxicol (1998) 1.01
Clinical pharmacokinetics of oral cephalosporins. Antibiot Chemother (1971) (1995) 0.96
Phase I trial of exisulind (sulindac sulfone, FGN-1) as a chemopreventive agent in patients with familial adenomatous polyposis. Clin Cancer Res (2000) 0.95
Kidney as a major clearance organ for recombinant human interleukin-1 receptor antagonist. J Pharm Sci (1995) 0.93
Evaluation of eight methods for estimating creatinine clearance in men. Clin Pharm (1987) 0.91
Allometric scaling of xenobiotic clearance: uncertainty versus universality. AAPS PharmSci (2001) 0.91
Serum binding of tocainide and its enantiomers in human subjects. Res Commun Chem Pathol Pharmacol (1982) 0.90
Intravenous recombinant secretory leukoprotease inhibitor augments antineutrophil elastase defense. J Appl Physiol (1985) (1992) 0.89
Methylprednisolone achieves greater concentrations in the lung than prednisolone. A pharmacokinetic analysis. Am Rev Respir Dis (1991) 0.88
Pharmacokinetics of ketamine in mules and mammoth asses premedicated with xylazine. Equine Vet J (1994) 0.88
Single-dose ceftriaxone kinetics in the newborn. Clin Pharmacol Ther (1985) 0.87
Postburn serum drug binding and serum protein concentrations. J Clin Pharmacol (1986) 0.86
Reduced muscle protein breakdown in septic rats following treatment with interleukin-1 receptor antagonist. Int J Biochem (1994) 0.84
Improved tumor imaging with radiolabeled monoclonal antibodies by plasma clearance of unbound antibody with anti-antibody column. Radiology (1991) 0.84
Pharmacokinetics of ketamine in the horse. Am J Vet Res (1979) 0.84
Pharmacodynamics of midodrine, an antihypotensive agent. Clin Pharmacol Ther (1986) 0.83
Architecture of the drug-drug interaction network. J Clin Pharm Ther (2011) 0.83
Impairment of learning or memory in the mature and old rat by diazepam. Psychopharmacology (Berl) (1981) 0.81
A physiologically based pharmacokinetic and pharmacodynamic model for paraoxon in rainbow trout. Toxicol Appl Pharmacol (1997) 0.81
Toxicokinetics of parathion and paraoxon in rainbow trout after intravascular administration and water exposure. Toxicol Appl Pharmacol (1996) 0.80
Relative stability of hetacillin and ampicillin in solution. J Pharm Sci (1972) 0.80
Effect of antacid and ascorbic acid on serum salicylate concentration. J Clin Pharmacol (1980) 0.80
Pharmacokinetics of diltiazem in selected animal species and human beings. Am J Cardiol (1982) 0.80
Tubocurarine and renal failure. Br J Anaesth (1972) 0.79
Metabolism of pentachlorophenol by fish. Xenobiotica (1989) 0.79
Pharmacokinetics of insulin-like growth factor-1 in advanced chronic renal failure. Kidney Int (1996) 0.79
Temperature dependence of di-2-ethylhexyl phthalate (DEHP) pharmacokinetics in rainbow trout. Toxicol Appl Pharmacol (1987) 0.79
Effect of pH on the accumulation kinetics of pentachlorophenol in goldfish. Arch Environ Contam Toxicol (1990) 0.79
Effects of thiosulfate on cyanide pharmacokinetics in dogs. Toxicol Appl Pharmacol (1983) 0.78
Pharmacokinetics of ketamine and two metabolites in the dog. J Pharmacokinet Biopharm (1980) 0.78
Effects of pH on the accumulation of sulfonamides by fish. J Pharmacokinet Biopharm (1981) 0.78
Paraquat pharmacokinetics using a subcutaneous toxic low dose in the rat. Fundam Appl Toxicol (1990) 0.77
Low-dose ethanol in the treatment of ethylene glycol poisoning. J Vet Pharmacol Ther (1985) 0.77
Pharmacokinetics of insulin-like growth factor I in hypopituitarism: correlation with binding proteins. Am J Physiol (1999) 0.76
Propellant-powered nebulizers. J Am Pharm Assoc (1976) 0.76
Detection of pentachlorophenol and its glucuronide and sulfate conjugates in fish bile and exposure water. J Environ Sci Health B (1988) 0.76
Effect of nasolacrimal occlusion on timolol concentrations in the aqueous humor of the human eye. J Pharm Sci (1992) 0.76
Effects of short and medium chain fatty acids on absorption of lipophilic drugs from perfused rat intestine. J Pharm Sci (1978) 0.75
Intestinal absorption kinetics using a laminar flow model. J Pharmacobiodyn (1989) 0.75
Effect of complex formation on drug absorption. XIV. Effect of N,N-di-n-propylpropionamide on intestinal absorption of certain nonsteroid drugs in the rat. J Pharm Sci (1972) 0.75
Effect of complex formation on drug absorption. XII. Enhancement of intestinal absorption of prednisone and prednisolone by dialkylpropionamides in rats. J Pharm Sci (1972) 0.75
Absorption of ethanol by the common guppy (Lebistes reticulatus). J Pharm Sci (1967) 0.75
Pharmacokinetics of intravenous chlorpheniramine in children. J Pharm Sci (1981) 0.75
Effect of complex formation on drug absorption. XI. Complexation of prednisone and prednisolone with dialkylpropionamides and its effect on prednisone transfer through an artificial lipoid barrier. J Pharm Sci (1972) 0.75
Serum binding of diltiazem in humans. J Clin Pharmacol (1982) 0.75
GI drug absorption in rats exposed to cobalt-60-gamma-radiation III: in situ intestinal absorption. J Pharm Sci (1977) 0.75
Presystemic branchial metabolism limits di-2-ethylhexyl phthalate accumulation in fish. Toxicol Appl Pharmacol (1989) 0.75
GI drug absorption in rats exposed to cobalt-60 gamma-radiation II: in vivo rate of absorption. J Pharm Sci (1977) 0.75
Effect of complex formation on drug absorption. 13. Effect of constant concentrations of N, N-di-n-propylpropionamide on prednisolone absorption from the rat small intestine. J Pharm Sci (1972) 0.75
Imaging of non-small cell lung cancers with a monoclonal antibody, KC-4G3, which recognizes a human milk fat globule antigen. Cancer Res (1990) 0.75
GI drug absorption in rats exposed to cobalt-60 gamma-radiation I: Extent of absorption. J Pharm Sci (1977) 0.75
Liquid chromatographic determination of acriflavine and proflavine residues in channel catfish muscle. J AOAC Int (1997) 0.75
Meperidine disposition in burn patients. Res Commun Chem Pathol Pharmacol (1986) 0.75
Characterization of proflavine metabolites in rainbow trout. Drug Metab Dispos (1997) 0.75
Preclinical absorption, distribution, metabolism and excretion (ADME) characterization of ICAM1988, an LFA-1/ICAM antagonist, and its prodrug. Xenobiotica (2008) 0.75
Body size and the toxicokinetics of trifluralin in rainbow trout. Toxicol Appl Pharmacol (1994) 0.75
The influence of ethanol withdrawal on the binding site of 3H-dopamine. Proc West Pharmacol Soc (1980) 0.75
Alteration of the pharmacokinetics of sodium cyanide by sodium thiosulfate. Proc West Pharmacol Soc (1981) 0.75
Saturable first-pass metabolism of sulfisoxazole N1-acetyl in rats. J Pharm Sci (1976) 0.75
Effect of 60CO gamma radiation on hexobarbital-induced sleeping times in rats. Radiat Res (1977) 0.75
Enhancement of steroid absorption by dialkylamides. J Pharm Sci (1970) 0.75
Chronic ethanol consumption causes increased glucuronidation of morphine in rabbits. Xenobiotica (1991) 0.75
Intestinal absorption of griseofulvin from a triolein digestion mixture in rats. J Pharm Sci (1978) 0.75
Temperature and surfactant dependence of accumulation of 4-aminoantipyrine and ethanol in fish. J Pharm Sci (1978) 0.75
Effects of normal alcohols on intestinal absorption of salicylic acid, sulfapyridine, and prednisolone in rats. J Pharm Sci (1975) 0.75
Methyltestosterone pharmacokinetics and oral bioavailability in rainbow trout (Oncorhynchus mykiss). Aquat Toxicol (2001) 0.75
Comparative study of 99mTc labeled hepatobiliary agents based on naphthalene and similar ring systems. Int J Nucl Med Biol (1982) 0.75
On the conversion of verapamil to carboxy verapamil. Res Commun Chem Pathol Pharmacol (1986) 0.75
Aging: changes in distribution of diazepam and metabolites in the rat. Drug Metab Dispos (1986) 0.75
Pharmacokinetics, tissue distribution and metabolism of acriflavine and proflavine in the channel catfish (Ictalurus punctatus). Xenobiotica (1998) 0.75
Effect of gamma-radiation on intestinal absorption of sulfanilamide. J Pharm Sci (1974) 0.75
Influence of ligand degradation on ligand binding assays. Proc West Pharmacol Soc (1986) 0.75
Quantification of benzocaine and its metabolites in channel catfish tissues and fluids by HPLC. J Pharm Biomed Anal (1997) 0.75
Pharmacokinetic evaluation of dosing regimens for insulin in diabetic ketoacidosis. Diabetes (1976) 0.75
Effect of SKF 525-A on drug absorption in rats. Life Sci I (1971) 0.75
A separation and purification procedure for [14C] di-2-ethylhexyl phthalate in fish. J Anal Toxicol (1984) 0.75
Comparison of 99mTc-N-pyridoxyl-5-methyltryptophan and 99mTc-N-(3-bromo-2,4,6-trimethylacetanilide)-iminodiace tate as hepatobiliary radiopharmaceuticals in rats. J Pharm Sci (1984) 0.75
Ketamine kinetics: decerebrate vs. intact cats. Can J Physiol Pharmacol (1979) 0.75
Rate-limiting barriers to intestinal drug absorption: a review. J Pharmacokinet Biopharm (1980) 0.75
Extraction, separation, and detections of 14C-diazepam and 14C-metabolites from brain tissue of mature and old rats. J Anal Toxicol (1985) 0.75
Aging: effects on beta-carboline binding in hippocampal subfields. Neurobiol Aging (1984) 0.75
Steady-state volume of distribution after multiple doses. J Pharm Sci (1985) 0.75
Apparent pH dependence of ethanol absorption rate in the common guppy. J Pharm Sci (1968) 0.75
Disposition of 14C-flumequine in eel Anguilla anguilla, turbot Scophthalmus maximus and halibut Hippoglossus hippoglossus after oral and intravenous administration. Dis Aquat Organ (2001) 0.75
Metabolic inhibition and di-2-ethylhexyl phthalate pharmacokinetics in fish. Drug Metab Dispos (1988) 0.75
Nonlinear pharmacokinetics of ethanol elimination in long sleep and short sleep mice. Alcohol Clin Exp Res (1983) 0.75
A pharmacokinetic model describing the removal of circulating radiolabeled antibody by extracorporeal immunoadsorption. J Pharmacokinet Biopharm (1991) 0.75
Kinetics of accumulation of trifluralin by fish. Proc West Pharmacol Soc (1981) 0.75
A readily obtainable analog of propranolol suitable for use as internal standard in chromatographic assays for propranolol. Res Commun Chem Pathol Pharmacol (1985) 0.75
Gas chromatographic determination of parathion and paraoxon in fish plasma and tissues. J Anal Toxicol (1996) 0.75
Effect of complex formation on drug absorption. XV. Structural requirements for enhancement of intestinal absorption of steroids by N,N-di-n-propylpropionamide. J Pharm Sci (1972) 0.75