Published in Nature on October 02, 1965
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A ligand-specific action of chelated copper on hypothalamic neurons: stimulation of the release of luteinizing hormone-releasing hormone from median eminence explants. Proc Natl Acad Sci U S A (1984) 0.77
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L-Dopa-induced release of cerebral monoamines. Science (1970) 1.47
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Biogenic amines and depression. Biochemical and pharmacological separation of two types of depression. Arch Gen Psychiatry (1975) 1.17
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Stimulation by lithium of monoamine uptake in human platelets. Life Sci (1969) 1.11
Quantitative studies of norepinephrine uptake by synaptosomes. Biochem Pharmacol (1968) 1.11
Noradrenaline, 5-hydroxytryptamine, and 5-hydroxyindoleacetic acid in hindbrains of suicidal patients. Lancet (1968) 1.09
Distinct regional and subcellular localization of adenylyl cyclases type 1 and 8 in mouse brain. Neuroscience (2007) 1.08
Behavioral effects of stimulation of the nucleus locus coeruleus in the stump-tailed monkey Macaca arctoides. Brain Res (1976) 1.00
Ageing, monoamines, and monoamine-oxidase levels. Lancet (1972) 0.95
The timing, specificity and clinical prediction of tricyclic drug effects in depression. Psychol Med (1987) 0.93
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Central biogenic amine metabolism in children with the syndrome of chronic multiple tics of Gilles de la Tourette: norepinephrine, serotonin, and dopamine. J Am Acad Child Psychiatry (1979) 0.92
Effect of lithium on the uptake of noradrenaline by synaptosomes. Nature (1967) 0.91
Release of ( 3 H)dopamine by L-5-hydroxytryptophan. Brain Res (1972) 0.91
Distribution of metal ions in the subcellular fractions of several rat brain areas. Life Sci (1976) 0.90
Co-ordination chemistry and membrane function with particular reference to the synapse and catecholamine transport. Nature (1965) 0.90
Localization of triiodothyronine in nerve ending fractions of rat brain. Proc Natl Acad Sci U S A (1976) 0.89
Pretreatment DST and hypothalamic-pituitary-adrenocortical function in depressed patients and comparison groups. A multicenter study. Arch Gen Psychiatry (1984) 0.89
Dopamine: stimulation-induced release from central neurons. Science (1971) 0.88
Effects of fire ant venom alkaloids on platelet and neutrophil function. Life Sci (1993) 0.88
An improved procedure of 3-methoxy-4-hydroxyphenyl-ethylene glycol determination by gas-liquid chromatography. Anal Biochem (1970) 0.88
In vivo studies of the metabolism of norepinephrine in the central nervous system. J Pharmacol Exp Ther (1968) 0.87
The time course of noradrenergic pre- and postsynaptic activity during chronic desipramine treatment. Eur J Pharmacol (1980) 0.87
Effects of L-dopa on efflux of cerebral monoamines from synaptosomes. Nature (1971) 0.86
Adrenocortical steroid hormones, electrolytes, and the disposition of the catecholamines with particular reference to depressive states. J Psychiatr Res (1972) 0.86
CSF and urinary biogenic amines and metabolites in depression and mania. A controlled, univariate analysis. Arch Gen Psychiatry (1983) 0.86
Can the spread of agriculture in Europe be followed by tracing the spread of the weed Silene latifolia. A RAPD study. Theor Appl Genet (1996) 0.86
Norcocaine: a pharmacologically active metabolite of cocaine found in brain. Life Sci (1974) 0.86
Imipramine and lithium effects of biogenic amine transport in depressed and manic-depressed patients. Am J Psychiatry (1970) 0.86
An exceptional case of tyrosinosis. J Ment Defic Res (1968) 0.85
Primary affective disorder, clinical state change, and MHPG excretion: a longitudinal study. Arch Gen Psychiatry (1978) 0.85
The novel, orally active, delta opioid RWJ-394674 is biotransformed to the potent mu opioid RWJ-413216. J Pharmacol Exp Ther (2006) 0.84
Mania. Diagnosis, state measurement and prediction of treatment response. J Affect Disord (1985) 0.83
Social behavior of monkeys selectively depleted of monoamines. Science (1971) 0.83
Drug-induced actions on brain neurotransmitter systems and changes in the behaviors and emotions of depressed patients. Neuropsychopharmacology (1994) 0.83
MHPG excretion by patients with affective disorders. Int Pharmacopsychiatry (1974) 0.83
Increased ouabain binding after repeated noradrenergic stimulation. Brain Res (1981) 0.83
Influence of age and cold stress on plasma catecholamine levels in rats. J Auton Nerv Syst (1984) 0.83
A schizophreniform behavioral psychosis mediated by dopamine. Am J Psychiatry (1975) 0.81
A multi-vantaged approach to measurement of behavioral and affect states for clinical and psychobiological research. Psychol Rep (1984) 0.81
Lithium treatment of mania: clinical characteristics, specificity of symptom change, and outcome. Psychiatry Res (1986) 0.81
Brain catecholamine metabolites and behavior in morphine withdrawal. Eur J Pharmacol (1982) 0.81
Evidence against specificity of electrical stimulation of the nucleus locus coeruleus in activating the sympathetic nervous system in the rat. Brain Res (1980) 0.81
Metal chelates in the storage and transport of neurotransmitters: formation of mixed ligand chelates of Mg 2+ -ATP with biogenic amines. J Neurochem (1972) 0.81
Effects of amitriptyline and imipramine on brain amine neurotransmitter metabolites in cerebrospinal fluid. Clin Pharmacol Ther (1985) 0.81
Analgesic effects of intrathecally-administered 3 alpha-hydroxy-5 alpha-pregnan-20-one in a rat mechanical visceral pain model. Life Sci (1992) 0.80
Estimates of dopamine and serotonin synthesis by the awake human brain. J Neurochem (1980) 0.80
CSF monoamine metabolites in mania. Am J Psychiatry (1983) 0.80
Effects of reserpine and tyramine on release of norepinephrine from synaptosomes. Biochem Pharmacol (1972) 0.80
Catecholamine metabolite excretion following intraventricular injection of 6-OH-dopamine. Brain Res (1972) 0.80
Urinary catecholamines in attention-deficit hyperactivity disorder with and without comorbid anxiety. J Am Acad Child Adolesc Psychiatry (1994) 0.79
Catecholamine metabolism and disposition in healthy and depressed subjects. Arch Gen Psychiatry (1987) 0.79
Attention deficit disorder symptoms and urine catecholamines. Psychiatry Res (1989) 0.79
The metabolism of circulating norepinephrine by human subjects. J Pharmacol Exp Ther (1971) 0.79
In vivo location and destruction of the locus coeruleus in the stumptail macaque (Macaca arctoides). Brain Res (1975) 0.79
3-Methoxy-4-hydroxy phenylglycol (MHPG) excretion in depressive states. A pilot study. Arch Gen Psychiatry (1968) 0.79
Calcium function in affective disorders and healthy controls. Biol Psychiatry (1988) 0.79
3-Methoxy-4-hydroxyphenethyleneglycol production by human brain in vivo. Science (1979) 0.78
Influence of ionophores which bind calcium on the release of norepinephrine from synaptosomes. Life Sci (1975) 0.78
Effects of chronic dietary lithium on activity and regulation of (Na+,K+)-adenosine triphosphatase in rat brain. Biochem Pharmacol (1980) 0.78
Dihydroxyphenylacetic acid conjugate: natural occurrence and demonstration of probenecid-induced accumulation in rat striatum, olfactory tubercles and frontal cortex. Eur J Pharmacol (1977) 0.78
Lithium carbonate treatment of mania. Cerebrospinal fluid and urinary monoamine metabolites and treatment outcome. Arch Gen Psychiatry (1987) 0.78
Regional distribution of dopamine metabolites in human and primate brain. Commun Psychopharmacol (1978) 0.78
Characterization of a neuropathic pain model: sciatic cryoneurolysis in the rat. Pain (1994) 0.78
Brain (Na+, K+)-ATPase and noradrenergic activity: effects of hyperinnervation and denervation on high-affinity ouabain binding. J Neurochem (1982) 0.78
Biochemistry and suicidal behavior in depressed patients. Biol Psychiatry (1986) 0.78
Comparative histopathology of epidural hydrogel and silicone elastomer catheters following 30 and 180 days implant in the ewe. Acta Anaesthesiol Scand (1994) 0.78
Presynaptic adrenergic receptor sensitivity in depression. The effect of long-term desipramine treatment. Arch Gen Psychiatry (1981) 0.78
Urinary catecholamine metabolites during behavioral changes in a patient with manic-depressive cycles. Science (1973) 0.78
The differentiation of NSAIDs and prostaglandin action using a mechanical visceral pain model in the rat. Pharmacol Biochem Behav (1989) 0.78
Distribution and excretion in the rat and monkey of [82Br] bromocriptine. J Pharmacol Exp Ther (1979) 0.78
Transfer RNA and the regulation of protein synthesis in rat cerebral cortex during neural development. J Neurochem (1974) 0.78
Stimulation of the dorsal noradrenergic dundle and field potentials in the locus coeruleus. Brain Res (1976) 0.78
Acute effects of neuroleptics on unmedicated schizophrenic patients and controls. Biol Psychiatry (1993) 0.78
The occurrence of free vs. conjugated MHPG in non-human and human primate brain. Psychopharmacol Commun (1976) 0.77
Plasma dopamine-beta-hydroxylase, HVA, MHPG, and conduct disorder in emotionally disturbed boys. Biol Psychiatry (1987) 0.77
Metal chelates in the storage and transport of neurotransmitters: interactions of Cu2+ with ATP and biogenic amines. J Neurochem (1974) 0.77
Catecholamine metabolism, depression and stress. Nature (1971) 0.77
Diagnoses, catecholamine metabolism, and plasma dopamine-beta-hydroxylase. J Am Acad Child Adolesc Psychiatry (1988) 0.77
Blood-brain barrier to 6-hydroxydopamine: uptake by heart and brain. Life Sci (1975) 0.77
Locus coeruleus stimulation increases noradrenergic metabolite levels in rat spinal cord. Brain Res (1979) 0.77
A direct method for studying 3-methoxy-4-hydroxyphenethyleneglycol (MHPG) production by brain in awake animals. Eur J Pharmacol (1977) 0.77
Depression and MHPG excretion. Response to dextroamphetamine and tricyclic antidepressants. Arch Gen Psychiatry (1972) 0.77
Hydrocortisone-mediated increase of norepinephrine uptake by brain slices. Science (1971) 0.77
Cerebrospinal fluid amine metabolites. Relationships with behavioral measurements in depressed, manic, and healthy control subjects. Arch Gen Psychiatry (1986) 0.77
A kinetic study of the disposition of circulating norepinephrine in normal male subjects. J Pharmacol Exp Ther (1970) 0.77
Stress, depression, and mania: relationship between perceived role of stressful events and clinical and biochemical characteristics. Acta Psychiatr Scand (1990) 0.77
A method for the preparation and separation of 3-methoxy-4-hydroxyphenethyleneglycol conjugates. Biochem Med (1975) 0.77
Mania: sympathoadrenal function and clinical state. Psychiatry Res (1991) 0.77
A kinetic model for the study of the disposition of circulating norepinephrine. J Pharmacol Exp Ther (1970) 0.77
Plasma free MHPG and neuroendocrine responses to challenge doses of clonidine in Tourette's syndrome: preliminary report. Life Sci (1981) 0.77