| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Amino acid transmitters in the mammalian central nervous system.
|
Ergeb Physiol
|
1974
|
5.99
|
|
2
|
GABA, bicuculline and central inhibition.
|
Nature
|
1970
|
3.55
|
|
3
|
Bicuculline, an antagonist of GABA and synaptic inhibition in the spinal cord of the cat.
|
Brain Res
|
1971
|
3.52
|
|
4
|
The structure of bovine rhodopsin.
|
Biophys Struct Mech
|
1983
|
3.33
|
|
5
|
The hyperpolarization of spinal motoneurones by glycine and related amino acids.
|
Exp Brain Res
|
1968
|
3.00
|
|
6
|
A pharmacological study of the depression of spinal neurones by glycine and related amino acids.
|
Exp Brain Res
|
1968
|
2.95
|
|
7
|
The pharmacology of amino acids related to gamma-aminobutyric acid.
|
Pharmacol Rev
|
1965
|
2.81
|
|
8
|
The specificity of strychnine as a glycine antagonist in the mammalian spinal cord.
|
Exp Brain Res
|
1971
|
2.41
|
|
9
|
Antagonism between bicuculline and GABA in the cat brain.
|
Brain Res
|
1971
|
2.29
|
|
10
|
Central synaptic transmission--microelectrophoretic studies.
|
Annu Rev Pharmacol
|
1969
|
2.17
|
|
11
|
Pharmacological studies on feline Betz cells.
|
J Physiol
|
1966
|
2.11
|
|
12
|
Spinal interneurone excitation by conformationally restricted analogues of L-glutamic acid.
|
Nature
|
1974
|
2.09
|
|
13
|
The acetylcholine receptors of Renshaw cells.
|
Exp Brain Res
|
1966
|
1.87
|
|
14
|
The synaptic excitation of Renshaw cells.
|
Exp Brain Res
|
1966
|
1.74
|
|
15
|
Phaclofen: a peripheral and central baclofen antagonist.
|
Brain Res
|
1987
|
1.66
|
|
16
|
Tetanus toxin and spinal inhibition.
|
Brain Res
|
1968
|
1.59
|
|
17
|
Excitation of mammalian central neurones by acidic amino acids.
|
Brain Res
|
1972
|
1.52
|
|
18
|
The excitation of Renshaw cells by cholinomimetics.
|
Exp Brain Res
|
1966
|
1.48
|
|
19
|
The effect of bicuculline upon synaptic inhibition in the cerebral and cerebellar corticles of the cat.
|
Brain Res
|
1971
|
1.47
|
|
20
|
Bicuculline methochloride as a GABA antagonist.
|
Nat New Biol
|
1972
|
1.40
|
|
21
|
New class of glutamate agonist structurally related to ibotenic acid.
|
Nature
|
1980
|
1.38
|
|
22
|
Structure and biological activity of a series of conformationally restricted analogues of GABA.
|
J Neurochem
|
1975
|
1.32
|
|
23
|
The inactivation of extracellularly administered amino acids in the feline spinal cord.
|
Exp Brain Res
|
1970
|
1.31
|
|
24
|
Tetanus toxin and the synaptic release of GABA.
|
Brain Res
|
1973
|
1.31
|
|
25
|
A new class of GABA agonist.
|
Nature
|
1977
|
1.28
|
|
26
|
Selective effects of (-)-baclofen on spinal synaptic transmission in the cat.
|
Exp Brain Res
|
1981
|
1.26
|
|
27
|
Acetylcholine sensitivity of cerebellar neurones in the cat.
|
J Physiol
|
1966
|
1.24
|
|
28
|
Bicuculline and central GABA receptors.
|
Nature
|
1970
|
1.23
|
|
29
|
The in vivo inactivation of GABA and other inhibitory amino acids in the cat nervous system.
|
Exp Brain Res
|
1976
|
1.20
|
|
30
|
Convulsive action of penicillin.
|
Brain Res
|
1972
|
1.19
|
|
31
|
Pharmacological studies upon spinal presynaptic fibres.
|
Exp Brain Res
|
1966
|
1.18
|
|
32
|
Central effects of beta-(para-chlorophenyl)-gamma-aminobutyric acid.
|
Brain Res
|
1974
|
1.17
|
|
33
|
Inhibition of spinal neurons by glycine.
|
Nature
|
1967
|
1.17
|
|
34
|
Central actions of benzodiazepines.
|
Brain Res
|
1976
|
1.16
|
|
35
|
GABA and hippocampal inhibition.
|
Br J Pharmacol
|
1970
|
1.14
|
|
36
|
A central action of hemicholinium.
|
Nature
|
1965
|
1.13
|
|
37
|
Selective antagonism by D-alpha-aminoadipate of amino acid and synaptic excitation of cat spinal neurons.
|
Brain Res
|
1978
|
1.12
|
|
38
|
Securinine alkaloids: a new class of GABA receptor antagonist.
|
Brain Res
|
1985
|
1.09
|
|
39
|
Central actions of ibotenic acid and muscimol.
|
Biochem Pharmacol
|
1968
|
1.08
|
|
40
|
The depolarization of feline ventral horn group Ia spinal afferent terminations by GABA.
|
Exp Brain Res
|
1982
|
1.08
|
|
41
|
Cis- and trans-4-aminocrotonic acid as GABA analogues of restricted conformation.
|
J Neurochem
|
1975
|
1.07
|
|
42
|
GABA and spinal afferent terminal excitability in the cat.
|
Brain Res
|
1977
|
1.03
|
|
43
|
Antagonism of neuronal excitation by 1-hydroxy-3-aminopyrrolidone-2.
|
Brain Res
|
1973
|
1.01
|
|
44
|
Pentobarbitone enhancement of the inhibitory action of GABA.
|
Nature
|
1977
|
1.00
|
|
45
|
Bicuculline and thalamic inhibition.
|
Exp Brain Res
|
1972
|
1.00
|
|
46
|
GABA and inhibition of Deiters' neurones.
|
Brain Res
|
1970
|
0.97
|
|
47
|
Effects of the Areca nut constituents arecaidine and guvacine on the action of GABA in the cat central nervous system.
|
Brain Res
|
1977
|
0.97
|
|
48
|
Does uptake limit the actions of GABA agonists in vivo? Experiments with muscimol, isoguvacine and THIP in cat spinal cord.
|
J Neurochem
|
1978
|
0.96
|
|
49
|
The differential sensitivity of spinal interneurones and Renshaw cells to Kainate and N-methyl-D-aspartate.
|
Exp Brain Res
|
1974
|
0.96
|
|
50
|
The action of cholinomimetics on spinal interneurones.
|
Exp Brain Res
|
1966
|
0.95
|
|
51
|
A pharmacological study of Renshaw cell inhibition.
|
J Physiol
|
1976
|
0.94
|
|
52
|
Strychnine and cortical inhibition.
|
Nature
|
1967
|
0.94
|
|
53
|
Piperidine-4-sulphonic acid, a new specific GABA agonist.
|
J Neurochem
|
1980
|
0.94
|
|
54
|
4-aminotetrolic acid: new conformational-restricted analogue of -aminobutyric acid.
|
Nat New Biol
|
1971
|
0.94
|
|
55
|
Noradrenaline and inhibition of Renshaw cells.
|
Science
|
1966
|
0.94
|
|
56
|
Potentiation of L-glutamate and L-aspartate excitation of cat spinal neurones by the stereoisomers of threo-3-hydroxyaspartate.
|
J Neurochem
|
1980
|
0.92
|
|
57
|
Phosphonic analogues as antagonists of amino acid excitants.
|
J Pharm Pharmacol
|
1977
|
0.92
|
|
58
|
In vivo inactivation of quisqualate: studies in the cat spinal cord.
|
Brain Res
|
1980
|
0.92
|
|
59
|
GABA and prolonged spinal inhibition.
|
Nat New Biol
|
1971
|
0.91
|
|
60
|
Strychnine, glycine and vertebrate postsynaptic inhibition.
|
Nature
|
1970
|
0.91
|
|
61
|
The differential effects of baclofen on segmental and descending excitation of spinal interneurones in the cat.
|
Exp Brain Res
|
1985
|
0.90
|
|
62
|
The depression of spinal inhibition by morphine.
|
Agents Actions
|
1969
|
0.89
|
|
63
|
Dihydromuscimol, thiomuscimol and related heterocyclic compounds as GABA analogues.
|
J Neurochem
|
1979
|
0.87
|
|
64
|
A method for assembly of "parallel" micro-pipettes.
|
Electroencephalogr Clin Neurophysiol
|
1968
|
0.87
|
|
65
|
Nuciferine and central glutamate receptors.
|
J Pharm Pharmacol
|
1979
|
0.87
|
|
66
|
Morphine and the synaptic activation of Renshaw cells.
|
Neuropharmacology
|
1972
|
0.86
|
|
67
|
Spinal interneurone depression by DS103-282.
|
Br J Pharmacol
|
1983
|
0.86
|
|
68
|
Synthesis and biological activity of a GABAA agonist which has no effect on benzodiazepine binding and of structurally related glycine antagonists.
|
Drug Des Deliv
|
1987
|
0.86
|
|
69
|
Depolarization of feline primary afferent fibres by acidic amino acids.
|
J Physiol
|
1984
|
0.85
|
|
70
|
Glycine, strychnine, picrotoxin and spinal inhibition.
|
Brain Res
|
1969
|
0.85
|
|
71
|
Glycine antagonists structurally related to muscimol, THIP, or isoguvacine.
|
J Neurochem
|
1982
|
0.85
|
|
72
|
Acetylcholine sensitivity of cerebellar neurones.
|
Nature
|
1965
|
0.85
|
|
73
|
Effects of noradrenaline and 5-hydroxytryptamine on spinal Ia afferent terminations.
|
Brain Res
|
1983
|
0.85
|
|
74
|
Central actions of shikimin and tutin.
|
Brain Res
|
1973
|
0.84
|
|
75
|
A method for continuously monitoring the electrical threshold of single intraspinal nerve fibers.
|
Electroencephalogr Clin Neurophysiol
|
1979
|
0.84
|
|
76
|
Antagonism of inhibitory amino acid action by tubocurarine.
|
Br J Pharmacol
|
1974
|
0.84
|
|
77
|
The dual effects of GABA and related amino acids on the electrical threshold of ventral horn group Ia afferent terminations in the cat.
|
Exp Brain Res
|
1982
|
0.83
|
|
78
|
An investigation of catecholamine receptors of spinal interneurones.
|
Int J Neuropharmacol
|
1966
|
0.83
|
|
79
|
The pharmacology of spinal postsynaptic inhibition.
|
Prog Brain Res
|
1969
|
0.82
|
|
80
|
The excitation and depression of spinal neurones by ibotenic acid.
|
J Physiol
|
1979
|
0.82
|
|
81
|
The carboxyl-terminal one-third of bovine rhodopsin: its structure and function.
|
Vision Res
|
1982
|
0.82
|
|
82
|
Antagonists of synaptic and amino acid excitation of neurones in the cat spinal cord.
|
Brain Res
|
1983
|
0.82
|
|
83
|
The effect of GABA on the terminations of vestibulospinal neurons in the cat spinal cord.
|
Brain Res
|
1984
|
0.82
|
|
84
|
Novel class of amino acid antagonists at non-N-methyl-D-aspartic acid excitatory amino acid receptors. Synthesis, in vitro and in vivo pharmacology, and neuroprotection.
|
J Med Chem
|
1991
|
0.82
|
|
85
|
Structure-activity studies on ibotenic acid and related muscimol analogues.
|
Adv Biochem Psychopharmacol
|
1981
|
0.81
|
|
86
|
Pyridazinyl-GABA derivatives as GABA and glycine antagonists in the spinal cord of the cat.
|
Neurosci Lett
|
1986
|
0.81
|
|
87
|
Benzodiazepines and central glycine receptors.
|
Br J Pharmacol
|
1976
|
0.81
|
|
88
|
Amino acid neurotransmitters and the brain. Beattie Smith lecture, March 28, 1974.
|
Med J Aust
|
1974
|
0.81
|
|
89
|
Baclofen antagonism by 4-amino-3-(5-methoxybenzo[b]furan-2-yl) butanoic acid in the cat spinal cord.
|
Neurosci Lett
|
1989
|
0.80
|
|
90
|
Kainate neurotoxicity and glutamate inactivation.
|
Neurosci Lett
|
1979
|
0.80
|
|
91
|
Glycine antagonism by RU 5135.
|
Eur J Pharmacol
|
1985
|
0.80
|
|
92
|
The synthesis and activity of cis- and trans-2-(aminomethyl) cyclopropanecarboxylic acid as conformationally restricted analogues of GABA.
|
J Neurochem
|
1980
|
0.79
|
|
93
|
Glutamic acid agonists. Stereochemical and conformational studies of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and related compounds.
|
Neurosci Lett
|
1982
|
0.79
|
|
94
|
Central action of bicuculline.
|
J Neurochem
|
1974
|
0.79
|
|
95
|
Electrical interaction between motoneurons and afferent terminals in cat spinal cord.
|
J Neurophysiol
|
1979
|
0.79
|
|
96
|
Glycine antagonists. Synthesis, structure, and biological effects of some bicyclic 5-isoxazolol zwitterions.
|
J Med Chem
|
1986
|
0.79
|
|
97
|
Effect of intracellular injection of pyridine nucleotides on electrical responses of cat spinal motoneurones.
|
Brain Res
|
1971
|
0.79
|
|
98
|
Recent advances in neuropharmacology of neurological interest.
|
Proc Aust Assoc Neurol
|
1968
|
0.79
|
|
99
|
Molecular pharmacology of the GABA receptors and GABA agonists.
|
Adv Biochem Psychopharmacol
|
1983
|
0.79
|
|
100
|
Ibotenic acid analogues. Synthesis and biological and in vitro activity of conformationally restricted agonists at central excitatory amino acid receptors.
|
J Med Chem
|
1984
|
0.78
|
|
101
|
GABA agonists. Resolution, absolute stereochemistry, and enantioselectivity of (S)-(+)- and (R)-(-)-dihydromuscimol.
|
J Med Chem
|
1985
|
0.78
|
|
102
|
John Carew Eccles 1903-1997.
|
Hist Rec Aust Sci
|
2001
|
0.78
|
|
103
|
Post-excitatory depression of neuronal firing by acidic amino acids and acetylcholine in the cat spinal cord.
|
Brain Res
|
1983
|
0.78
|
|
104
|
A pharmacological study of group I muscle afferent terminals and synaptic excitation in the intermediate nucleus and Clarke's column of the cat spinal cord.
|
Exp Brain Res
|
1986
|
0.78
|
|
105
|
The effect of GABA on lumbar terminations of rubrospinal neurons in the cat spinal cord.
|
Proc R Soc Lond B Biol Sci
|
1984
|
0.78
|
|
106
|
A pharmacological study of the inhibition of ventral group Ia-excited spinal interneurones.
|
Exp Brain Res
|
1977
|
0.78
|
|
107
|
On the existence of Renshaw cells.
|
Brain Res
|
1969
|
0.78
|
|
108
|
Effect of pentobarbitone on the inhibition of spinal interneurones in the cat by glycine and GABA [proceedings].
|
J Physiol
|
1977
|
0.77
|
|
109
|
Thienyl-GABA derivatives as specific baclofen agonists in the rat and cat spinal cord in vivo.
|
Neurosci Lett
|
1993
|
0.77
|
|
110
|
Differing actions of nitropropane analogs of GABA and baclofen in central and peripheral preparations.
|
Eur J Pharmacol
|
1994
|
0.77
|
|
111
|
In vivo analysis of GABA receptors on primary afferent terminations in the cat.
|
Brain Res
|
1980
|
0.77
|
|
112
|
Sir John Carew Eccles, A.C.
|
Biogr Mem Fellows R Soc
|
2001
|
0.77
|
|
113
|
Central effects of beta-N-oxalyl-alpha,beta-diaminopropionic acid and other lathyrus factors.
|
Nature
|
1966
|
0.77
|
|
114
|
Tetanus toxin and amino acid levels in cat spinal cord.
|
J Neurochem
|
1969
|
0.76
|
|
115
|
4,5,6,7-Tetrahydroisothiazolo[5,4-c]pyridin-3-ol and related analogues of THIP. Synthesis and biological activity.
|
J Med Chem
|
1983
|
0.76
|
|
116
|
Phosphinic acid derivatives as baclofen agonists and antagonists in the mammalian spinal cord: an in vivo study.
|
Exp Brain Res
|
1994
|
0.76
|
|
117
|
Synthesis and single cell pharmacology of potential heterocyclic bioisosteres of the excitatory amino acid antagonist glutamic acid diethyl ester.
|
Acta Chem Scand
|
1990
|
0.76
|
|
118
|
[Inhibitory effect of glycine and similar amino acids on spinal neurons].
|
Helv Physiol Pharmacol Acta
|
1968
|
0.76
|
|
119
|
Dual effects of hemicholinium-3 at central cholinergic synapses.
|
J Physiol
|
1977
|
0.75
|
|
120
|
A neurophysiological analysis of the effect of kainic acid on nerve fibres and terminals in the cat spinal cord.
|
J Physiol
|
1985
|
0.75
|
|
121
|
GABA synapses in the brain.
|
Trends Neurosci
|
1995
|
0.75
|
|
122
|
Neurotoxicity of kainate and the inactivation of L-glutamate in vivo [proceedings].
|
Br J Pharmacol
|
1980
|
0.75
|
|
123
|
Actions of amino-acids on the isolated hemisected spinal cord of the toad. 1961.
|
Br J Pharmacol
|
1997
|
0.75
|
|
124
|
Excitatory amino acid agonists. Enzymic resolution, X-ray structure, and enantioselective activities of (R)- and (S)-bromohomoibotenic acid.
|
J Med Chem
|
1989
|
0.75
|
|
125
|
GABA-mimetic activity and effects on diazepam binding of aminosulphonic acids structurally related to piperidine-4-sulphonic acid.
|
J Neurochem
|
1985
|
0.75
|
|
126
|
Bicuculline and visual responses.
|
Nature
|
1976
|
0.75
|
|
127
|
On the probable absence of GABA receptors on the terminations of motor axon collaterals in the cat spinal cord.
|
Exp Brain Res
|
1986
|
0.75
|
|
128
|
Ouabain and the membrane transport of amino acids and amines.
|
Neurochem Res
|
1987
|
0.75
|
|
129
|
Post-tetanic influences on primary afferent depolarization in the cat spinal cord.
|
Exp Brain Res
|
1989
|
0.75
|
|
130
|
The effects of naloxone, morphine and methionine enkephalinamide on Ia afferent terminations in the cat spinal cord.
|
Brain Res
|
1984
|
0.75
|
|
131
|
The partial primary structure of bovine rhodopsin and its topography in the retinal rod cell disc membrane.
|
Neurochem Int
|
1980
|
0.75
|
|
132
|
Lack of specificity of a "taurine antagonist".
|
Brain Res
|
1982
|
0.75
|
|
133
|
In vitro and in vivo effects of pentobarbitone sodium.
|
J Pharm Pharmacol
|
1982
|
0.75
|
|
134
|
Acetylcholine, strychnine and spinal inhibition.
|
Nature
|
1967
|
0.75
|
|
135
|
Central actions of amino-oxyacetic acid.
|
Brain Res
|
1977
|
0.75
|
|
136
|
Preparation of peptides containing any desired amino acid: methionyl peptides of bovine rhodopsin.
|
Prep Biochem
|
1983
|
0.75
|
|
137
|
Actions of midazolam in the spinal cord of the cat.
|
Neuropharmacology
|
1983
|
0.75
|
|
138
|
Bicuculline, GABA and central inhibition.
|
Proc Aust Assoc Neurol
|
1973
|
0.75
|
|
139
|
Synthesis and structure-activity studies on excitatory amino acids structurally related to ibotenic acid.
|
J Med Chem
|
1985
|
0.75
|
|
140
|
Ibotenic acid analogues. Synthesis and biological testing of two bicyclic 3-isoxazolol amino acids.
|
Acta Chem Scand B
|
1986
|
0.75
|
|
141
|
Preparation of peptides from bovine rhodopsin.
|
Methods Enzymol
|
1982
|
0.75
|
|
142
|
Configuration of bicuculline, a GABA antagonist.
|
Nat New Biol
|
1973
|
0.75
|
|
143
|
Pitrazepin: a central glycine and GABA antagonist.
|
Eur J Pharmacol
|
1986
|
0.75
|
|
144
|
Cyclobutane analogs of GABA.
|
Neurochem Res
|
1980
|
0.75
|
|
145
|
[Amino acid neuromediators].
|
Farmakol Toksikol
|
1990
|
0.75
|
|
146
|
-Aminobutyrylcholine and central inhibition.
|
J Pharm Pharmacol
|
1972
|
0.75
|
|
147
|
In vivo effects of GABA uptake inhibitors on the response of cat spinal neurones to GABA analogues [proceedings].
|
Br J Pharmacol
|
1977
|
0.75
|
|
148
|
Selective antagonist activity of 5-aminohex-2-enedioic acid on amino acid excitation of cat spinal neurones.
|
Neurosci Lett
|
1980
|
0.75
|
|
149
|
Central synaptic transmitters.
|
Proc Aust Assoc Neurol
|
1970
|
0.75
|