Published in Nature on December 08, 1977
Routes of Immunization and Flu Immune Responses (FLUWAY) | NCT01707602
Impaired assembly and transport of HLA-A and -B antigens in a mutant TxB cell hybrid. EMBO J (1986) 3.78
Cellular immune correlates of protection against symptomatic pandemic influenza. Nat Med (2013) 3.03
Structure of crossreactive human histocompatibility antigens HLA-A28 and HLA-A2: possible implications for the generation of HLA polymorphism. Proc Natl Acad Sci U S A (1982) 2.36
Recognition of influenza A matrix protein by HLA-A2-restricted cytotoxic T lymphocytes. Use of analogues to orientate the matrix peptide in the HLA-A2 binding site. J Exp Med (1988) 1.97
Distribution of HLA class 1 antigens in normal human tissue and in mammary cancer. J Clin Pathol (1981) 1.87
Immune interferon produced to high levels by antigenic stimulation of human lymphocytes with influenza virus. J Exp Med (1981) 1.64
Histocompatibility and liver transplant outcome. Does HLA exert a dualistic effect? Transplantation (1988) 1.61
HLA antigen-related restriction of T lymphocyte cytotoxicity to Epstein-Barr virus. Proc Natl Acad Sci U S A (1980) 1.60
HLA restriction of human cytotoxic T lymphocytes specific for influenza virus. Poor recognition of virus associated with HLA A2. J Exp Med (1978) 1.56
Medawar's legacy to cellular immunology and clinical transplantation: a commentary on Billingham, Brent and Medawar (1956) 'Quantitative studies on tissue transplantation immunity. III. Actively acquired tolerance'. Philos Trans R Soc Lond B Biol Sci (2015) 1.40
Identification of human genomic clones coding the major histocompatibility antigens HLA-a2 and HLA-B7 by DNA-mediated gene transfer. Proc Natl Acad Sci U S A (1982) 1.39
The role of host genetics in susceptibility to influenza: a systematic review. PLoS One (2012) 1.39
Differentiation-dependent sensitivity of human B-cell-derived lines to major histocompatibility complex-restricted T-cell cytotoxicity. Proc Natl Acad Sci U S A (1986) 1.38
Influenza virus hemagglutinin-specific cytotoxic T cell response induced by polypeptide produced in Escherichia coli. J Exp Med (1985) 1.37
Immunological function of HLA-C antigens in HLA-Cw3 transgenic mice. Proc Natl Acad Sci U S A (1988) 1.29
Absence of allogeneic restriction in human T-cell-mediated cytotoxicity to Epstein-Barr virus-infected target cells. Demonstration of an HLA-linked control at the effector level. J Exp Med (1979) 1.27
HLA-linked genetic control of the specicity of human cytotoxic T-cell responses to influenza virus. J Exp Med (1979) 1.23
Immunohistochemical analysis of HLA (A, B, C) antigens in liver disease using a monoclonal antibody. Gut (1981) 1.23
Anti-self HLA may be clonally expressed. J Exp Med (1979) 1.10
HLA antigen structural gene mutants selected with an allospecific monoclonal antibody. Proc Natl Acad Sci U S A (1982) 1.10
Bovine alloreactive cytotoxic cells generated in vitro: target specificity in relation to BoLA phenotype. Immunology (1985) 1.07
Killing of measles virus-infected cells by human cytotoxic T cells. Infect Immun (1982) 1.06
Kinetics of cytotoxic lymphocytes in efferent lymph from single lymph nodes following immunization with vaccinia virus. Clin Exp Immunol (1984) 1.05
Cytomegalovirus-specific cytotoxicity mediated by non-T lymphocytes from peripheral blood of normal volunteers. Infect Immun (1981) 1.03
Cellular changes in lungs of mice infected with influenza virus: characterization of the cytotoxic responses. Infect Immun (1978) 1.01
Localization of interferons and interleukin 2 in polymyositis and muscular dystrophy. Clin Exp Immunol (1986) 1.01
Recognition of hapten-modified cells in vitro by human T-lymphocytes. J Clin Invest (1979) 0.99
Cross-reactivity of self-HLA-restricted Epstein-Barr virus-specific cytotoxic T lymphocytes for allo-HLA determinants. J Exp Med (1983) 0.97
Cytotoxic lymphocytes and antibody-dependent complement-mediated cytotoxicity induced by administration of influenza vaccine. Infect Immun (1980) 0.97
Rapid screening for Mamu-A1-positive rhesus macaques using a SIVmac Gag peptide-specific cytotoxic T-lymphocyte assay. Immunology (1995) 0.97
Human cytotoxic T-cell responses to type A and type B influenza viruses can be restricted by different HLA antigens. Implications for HLA polymorphism and genetic regulation. J Exp Med (1980) 0.96
HLA-restricted T lymphocyte-mediated cytotoxicity against herpes simplex virus-infected cells in humans. Infect Immun (1983) 0.95
Enhancement by interferon of membrane HLA antigens in patients with combined immunodeficiency with defective HLA expression. Clin Exp Immunol (1983) 0.95
In situ analysis of the mononuclear cell infiltrate in primary malignant melanoma of the skin. Clin Exp Immunol (1983) 0.95
Immune human lymphocytes produce an acid-labile alpha-interferon. J Exp Med (1983) 0.95
Major histocompatibility complex-restricted H-Y-specific antibodies and cytotoxic T lymphocytes may recognize different self determinants. J Exp Med (1982) 0.89
Public antigenic determinant on a family of HLA-B molecules. J Clin Invest (1979) 0.88
T-cell-mediated cytotoxic response to mumps virus in humans. Infect Immun (1980) 0.87
Epstein-Barr virus-specific cytotoxic T lymphocytes as probes of HLA polymorphism. Heterogeneity of T cell-restricting determinants associated with the serologically defined HLA-A2 antigen. J Exp Med (1983) 0.87
Alloreactivity studied with mutants of HLA-A2. Proc Natl Acad Sci U S A (1989) 0.85
Accessory cell and HLA compatibility requirements for the generation of specific in-vitro antibody responses to influenza virus by human blood lymphocytes. Immunology (1983) 0.85
HIV in the lung: guilty or not guilty? Thorax (1993) 0.85
Induction of HLA-DR expression on thyroid follicular cells by cytomegalovirus infection in vitro. Evidence for a dual mechanism of induction. Am J Pathol (1991) 0.83
Proliferative T-cell response to glycoprotein B of the human herpes viruses: the influence of MHC and sequence of infection on the pattern of cross-reactivity. Immunology (1989) 0.80
Rheumatoid arthritis--a virus disease? J Clin Pathol Suppl (R Coll Pathol) (1978) 0.79
Primed lymphocyte testing specificity of alloreactive lymphocyte clones for HLA-B locus determinants. Proc Natl Acad Sci U S A (1983) 0.78
Cell-mediated cytotoxicity for cultured autologous rheumatoid synovial membrane cells. Ann Rheum Dis (1980) 0.77
Lymphocyte function and disease. Br Med J (1978) 0.77
Expression of HLA-B27 antigens on mononuclear leucocytes in ankylosing spondylitis. Clin Exp Immunol (1985) 0.76
Lymphocytes. 1. Function. Genetic restrictions in the immune response. J Clin Pathol Suppl (R Coll Pathol) (1979) 0.76
Anti-influenza human T killer cells present an intertypic activity anti-A and -B type viruses in a secondary reaction in vitro. Clin Exp Immunol (1983) 0.75
Bovine alloreactive cytotoxic cells generated in vitro detect BoLA w6 subgroups. Immunology (1987) 0.75
Phenotypic analysis of antigen-specific T lymphocytes. Science (1996) 24.26
The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell (1986) 14.96
Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS. Nat Med (1997) 12.26
Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA. Science (1998) 12.05
Polypeptide components of virions, top component and cores of reovirus type 3. Virology (1969) 9.83
Common west African HLA antigens are associated with protection from severe malaria. Nature (1991) 9.43
Cytotoxic T-cell immunity to influenza. N Engl J Med (1983) 8.49
Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature (2001) 7.90
Bias due to misclassification in the estimation of relative risk. Am J Epidemiol (1977) 7.28
HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature (1998) 7.12
Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses. J Exp Med (2001) 6.51
Standardized mortality ratios and the "healthy worker effect": Scratching beneath the surface. J Occup Med (1976) 6.40
Rapid effector function in CD8+ memory T cells. J Exp Med (1997) 6.36
Alcohol, tobacco and breast cancer--collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease. Br J Cancer (2002) 5.83
Biological properties of an influenza A virus-specific killer T cell clone. Inhibition of virus replication in vivo and induction of delayed-type hypersensitivity reactions. J Exp Med (1981) 5.82
HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function. J Exp Med (2000) 5.79
Environmental exposure to lead and children's intelligence at the age of seven years. The Port Pirie Cohort Study. N Engl J Med (1992) 5.49
HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides. Nature (1988) 5.45
Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus In vivo. J Exp Med (1998) 5.33
A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody. Eur J Immunol (1979) 5.17
Potential impact of global climate change on malaria risk. Environ Health Perspect (1995) 4.44
Cytotoxic T cells to type A influenza virus; viral hemagglutinin induces A-strain specificity while infected cells confer cross-reactive cytotoxicity. Eur J Immunol (1977) 4.05
Cytotoxic T cell recognition of the influenza nucleoprotein and hemagglutinin expressed in transfected mouse L cells. Cell (1984) 3.97
Large clonal expansions of CD8+ T cells in acute infectious mononucleosis. Nat Med (1996) 3.94
Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T lymphocytes after combination antiretroviral therapy. J Virol (1999) 3.79
Isoelectric focusing in polyacrylamide gel and its application to immunoglobulins. Nature (1968) 3.73
Cytotoxic T cells kill influenza virus infected cells but do not distinguish between serologically distinct type A viruses. Nature (1977) 3.67
Excess mortality in England and Wales, and in Greater London, during the 1995 heatwave. J Epidemiol Community Health (1998) 3.67
Influenza nucleoprotein-specific cytotoxic T-cell clones are protective in vivo. Immunology (1986) 3.59
Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J Clin Invest (1998) 3.53
Cytotoxic T cells clear virus but augment lung pathology in mice infected with respiratory syncytial virus. J Exp Med (1988) 3.39
A re-evaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers. J Immunol (1999) 3.36
Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40. Science (2000) 3.20
Immune interferon release when a cloned cytotoxic T-cell line meets its correct influenza-infected target cell. Nature (1982) 3.17
Studies on the intracellular synthesis of reovirus-specified proteins. Virology (1970) 3.17
Primary stimulation by dendritic cells induces antiviral proliferative and cytotoxic T cell responses in vitro. J Exp Med (1989) 3.16
The localization of antigen in relation to specific antibody-producing cells. I. Use of a synthetic polypeptide [(T,G)-A--L] labelled with iodine-125. Immunology (1966) 3.09
A human lymphocyte-associated antigen involved in cell-mediated lympholysis. Eur J Immunol (1983) 3.08
Novel, cross-restricted, conserved, and immunodominant cytotoxic T lymphocyte epitopes in slow progressors in HIV type 1 infection. AIDS Res Hum Retroviruses (1996) 3.01
Ecological study of reasons for sharp decline in mortality from ischaemic heart disease in Poland since 1991. BMJ (1998) 2.94
Persistence of immunogenicity of antigen after uptake by macrophages. J Exp Med (1968) 2.93
Extensive conservation of alpha and beta chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza A matrix peptide. Proc Natl Acad Sci U S A (1991) 2.90
Cytotoxic T-cell recognition of HIV proteins and peptides. AIDS (1991) 2.83
A recombinant vaccinia virus based ELISPOT assay detects high frequencies of Pol-specific CD8 T cells in HIV-1-positive individuals. AIDS (1999) 2.75
High frequency of memory and effector gag specific cytotoxic T lymphocytes in HIV seropositive individuals. Int Immunol (1990) 2.71
Early effects of climate change: do they include changes in vector-borne disease? Philos Trans R Soc Lond B Biol Sci (2001) 2.71
HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi. J Immunol (2000) 2.69
Activation of mouse complement by different classes of mouse antibody. Immunology (1979) 2.68
The immune response of mice to antigen in macrophages. Immunology (1968) 2.67
Direct ex vivo analysis of hepatitis B virus-specific CD8(+) T cells associated with the control of infection. Gastroenterology (1999) 2.62
Correlation of grain counts with radioactivity (125I and tritium) in autoradiography. Exp Cell Res (1966) 2.62
A monoclonal antibody that recognizes an antigenic determinant shared by HLA A2 and B17. Hum Immunol (1980) 2.56
Cross-protection and cross-reactive cytotoxic T cells induced by influenza virus vaccines in mice. Eur J Immunol (1980) 2.52
Fate of parental reovirus in infected cell. Virology (1971) 2.49
Misconceptions about the use of genetic tests in populations. Lancet (2001) 2.48
The detailed distribution of HLA-A, B, C antigens in normal human organs. Transplantation (1984) 2.45
Environment and health: 2. Global climate change and health. CMAJ (2000) 2.45
Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2. Nature (1997) 2.41
Suppressor cells and loss of B-cell potential in mice infected with Trypanosoma brucei. Clin Exp Immunol (1977) 2.40
Influenza virus-specific cytotoxic T cells in man; induction and properties of the cytotoxic cell. Eur J Immunol (1978) 2.39
One cell-one immunoglobulin. Origin of limited heterogeneity of myeloma proteins. Biochem J (1970) 2.36
Declining T-cell immunity to influenza, 1977-82. Lancet (1983) 2.34
An epidemiologic study of mortality within a cohort of rubber workers, 1964-72. J Occup Med (1974) 2.33
Sequence motifs important for peptide binding to the human MHC class I molecule, HLA-A2. J Immunol (1992) 2.32
Persistent high frequency of human immunodeficiency virus-specific cytotoxic T cells in peripheral blood of infected donors. Proc Natl Acad Sci U S A (1995) 2.30
Biosynthesis of immunoglobulins: the separate classes of polyribosomes synthesizing heavy and light chains. J Mol Biol (1967) 2.30
Induction of AIDS virus-specific CTL activity in fresh, unstimulated peripheral blood lymphocytes from rhesus macaques vaccinated with a DNA prime/modified vaccinia virus Ankara boost regimen. J Immunol (2000) 2.29
Mortality among rubber workers: Relationship to specific jobs. J Occup Med (1976) 2.27
The detailed distribution of MHC Class II antigens in normal human organs. Transplantation (1984) 2.26
Immunoglobulin M biosynthesis. Intracellular accumulation of 7S subunits. Biochem J (1969) 2.24
CD8(+) T-cell selection, function, and death in the primary immune response in vivo. J Clin Invest (2000) 2.19
Reproduction, endogenous and exogenous sex hormones, and colon cancer: a review and hypothesis. J Natl Cancer Inst (1980) 2.17
Recognition of influenza A virus nucleoprotein by human cytotoxic T lymphocytes. J Gen Virol (1986) 2.16
Oligoclonal expansions of CD8(+) T cells in chronic HIV infection are antigen specific. J Exp Med (1998) 2.13
Human and murine cytotoxic T cells specific to respiratory syncytial virus recognize the viral nucleoprotein (N), but not the major glycoprotein (G), expressed by vaccinia virus recombinants. J Immunol (1986) 2.13
Assessing ecosystem health. Trends Ecol Evol (1998) 2.11
HLA B37 determines an influenza A virus nucleoprotein epitope recognized by cytotoxic T lymphocytes. J Exp Med (1986) 2.09
A role of macrophages in the stimulation of immune responses by adjuvants. J Immunol (1969) 2.06
Sun exposure and vitamin D are independent risk factors for CNS demyelination. Neurology (2011) 2.04
Clearance of persistent respiratory syncytial virus infections in immunodeficient mice following transfer of primed T cells. Immunology (1987) 2.02
Solvent exposure and leukemia among rubber workers: an epidemiologic study. J Occup Med (1975) 2.00
Cross-reactivity for different type A influenza viruses of a cloned T-killer cell line. Nature (1980) 1.98
Class I MHC molecules rather than other mouse genes dictate influenza epitope recognition by cytotoxic T cells. Immunogenetics (1987) 1.97
The minimum peptide epitope from the influenza virus matrix protein. Extra and intracellular loading of HLA-A2. J Immunol (1991) 1.96
Increased frequency of HLA-Cw3 and HLA-Dw4 in rheumatoid arthritis. Arthritis Rheum (1977) 1.95
Declining blood lead levels and changes in cognitive function during childhood: the Port Pirie Cohort Study. JAMA (1998) 1.95
Cytotoxic T-cell response to respiratory syncytial virus in mice. J Virol (1985) 1.92
Direct visualization of HIV-1-specific cytotoxic T lymphocytes during primary infection. AIDS (2000) 1.92
Vitamin D levels in people with multiple sclerosis and community controls in Tasmania, Australia. J Neurol (2007) 1.92
Selection of a single antibody-forming cell clone and its propagation in syngeneic mice. Proc Natl Acad Sci U S A (1970) 1.89
The Port Pirie cohort study: maternal blood lead and pregnancy outcome. J Epidemiol Community Health (1986) 1.89
Diversity in the biological properties of anti-influenza cytotoxic T cell clones. Eur J Immunol (1983) 1.87
Does breastfeeding at six months predict cognitive development? Aust N Z J Public Health (1998) 1.87
HLA class I typing by PCR: HLA-B27 and an African B27 subtype. Lancet (1991) 1.86
Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses. J Clin Invest (2001) 1.85