Distribution of 5 s RNA in HeLa cells.

Ribonucleic acids from animal cells. Bacteriol Rev (1968) 6.13

A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes Dev (2002) 6.10

The JAK-STAT pathway at twenty. Immunity (2012) 4.41

The turnover of nuclear DNA-like RNA in HeLa cells. J Cell Biol (1968) 3.39

A 5S rRNA/L5 complex is a precursor to ribosome assembly in mammalian cells. J Cell Biol (1988) 2.08

Isolation of a 5S RNA-protein complex from mammalian ribosomes. Proc Natl Acad Sci U S A (1971) 2.04

Intracellular distribution of low molecular weight RNA species in HeLa cells. J Cell Biol (1980) 1.52

5S ribosomal RNA is an essential component of a nascent ribosomal precursor complex that regulates the Hdm2-p53 checkpoint. Cell Rep (2013) 1.37

Analysis of the 5S RNA pool in Arabidopsis thaliana: RNAs are heterogeneous and only two of the genomic 5S loci produce mature 5S RNA. Genome Res (2002) 1.16

Membranes of animal cells. 3. Amino acid incorporation by isolated surface membranes. Proc Natl Acad Sci U S A (1969) 1.12

Small ribosomal ribonucleic acid species of Saccharomyces cerevisiae. J Bacteriol (1971) 1.08

Stimulation by insulin of RNA synthesis in chick fibroblasts. J Cell Biol (1974) 1.06

Intracellular distribution of low molecular weight RNA in Chironomus tentans. J Cell Biol (1971) 0.86

Chaperoning 5S RNA assembly. Genes Dev (2015) 0.83

Effects of cycloheximide and 5-fluorouracil on formation of low-molecular-weight ribonucleic acid in yeast. J Bacteriol (1969) 0.82

Characterization by human antibodies of two HeLa cell proteins which are related to Xenopus laevis transcription factor TFIIIA. Nucleic Acids Res (1988) 0.78

The effect of puromycin on intranuclear steps in ribosome biosynthesis. J Cell Biol (1968) 0.78

The Relationship between the Kinetics of Ribonucleic Acid Accumulation and the Morphological Development of the Fern Gametophyte, Dryopteris borreri. Plant Physiol (1970) 0.77

Preparation of polyribosome aminoacyl-transfer ribonucleic acid from the muscle of chick embryos. Biochem J (1975) 0.76

E.B. Wilson Lecture, 1998. Eukaryotic RNAs: once more from the beginning. Mol Biol Cell (1999) 0.75

Biosynthesis and maturation of low-molecuar-weight riboncleic acid species. Biochem J (1969) 0.75

Turnover of HeLa ribosomal RNA. The characterization of a class of RNA in HeLa cytoplasm derived from 28S RNA. J Cell Biol (1971) 0.75

Control of 5S RNA synthesis during early development of anucleolate and partial nucleolate mutants of Xenopus laevis. J Cell Biol (1973) 0.75

Increased synthesis of low-molecular-weight nuclear ribonucleic acids of rat liver after gamma irradiation and hepatectomy. Biochem J (1975) 0.75

Stat3 as an oncogene. Cell (1999) 17.39

Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol (2002) 15.33

POLYRIBOSOMES IN NORMAL AND POLIOVIRUS-INFECTED HELA CELLS AND THEIR RELATIONSHIP TO MESSENGER-RNA. Proc Natl Acad Sci U S A (1963) 12.17

Evidence for virus-specific noncapsid proteins in poliovirus-infected HeLa cells. Proc Natl Acad Sci U S A (1965) 11.84

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science (1994) 11.33

An adenylic acid-rich sequence in messenger RNA of HeLa cells and its possible relationship to reiterated sites in DNA. Proc Natl Acad Sci U S A (1971) 11.01

Polyadenylic acid sequences: role in conversion of nuclear RNA into messenger RNA. Science (1971) 10.54

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell (1995) 10.16

Variety in the level of gene control in eukaryotic cells. Nature (1982) 9.61

Transcriptional control in the production of liver-specific mRNAs. Cell (1981) 9.35

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu Rev Biochem (1995) 8.52

A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma. Science (1993) 6.44

The role of STATs in transcriptional control and their impact on cellular function. Oncogene (2000) 6.42

Steps in the processing of Ad2 mRNA: poly(A)+ nuclear sequences are conserved and poly(A) addition precedes splicing. Cell (1978) 6.36

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev (1990) 6.33

Ribonucleic acids from animal cells. Bacteriol Rev (1968) 6.13

Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science (1992) 6.09

Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control. Genes Dev (1988) 6.08

Aspects of the synthesis of poliovirus RNA and the formation of virus particles. Virology (1966) 5.85

ATP-dependent reduction of azide and HCN by N2-fixing enzymes of Azotobacter vinelandii and Clostridium pasteurianum. Biochim Biophys Acta (1967) 5.81

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions. Cell (1994) 5.79

The primary transcription unit of the mouse beta-major globin gene. Cell (1981) 5.75

Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein. Science (1992) 5.71

Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha. Proc Natl Acad Sci U S A (1992) 5.50

Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro. Genes Dev (1989) 5.09

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science (1995) 4.90

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nat Genet (1996) 4.84

Transcriptional induction of two genes in human cells by beta interferon. Proc Natl Acad Sci U S A (1984) 4.84

Rapidly labeled HeLa cell nuclear RNA. I. Identification by zone sedimentation of a heterogeneous fraction separate from ribosomal precursor RNA. J Mol Biol (1966) 4.83

The initiation sites for RNA transcription in Ad2 DNA. Cell (1977) 4.76

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors. Science (1993) 4.65

Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element. Proc Natl Acad Sci U S A (1987) 4.61

Identification of the membrane protein and "core" protein of Sindbis virus. Proc Natl Acad Sci U S A (1968) 4.52

Addition of polyadenylate sequences to virus-specific RNA during adenovirus replication. Proc Natl Acad Sci U S A (1971) 4.48

Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes. Mol Cell Biol (1989) 4.47

Characterization of a new low molecular weight RNA in HeLa cell ribosomes. J Mol Biol (1968) 4.44

Sindbis virus infection of chick and hamster cells: synthesis of virus-specific proteins. Virology (1969) 4.38

Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways. EMBO J (1993) 4.35

The definition of a large viral transcription unit late in Ad2 infection of HeLa cells: mapping by effects of ultraviolet irradiation. Cell (1977) 4.13

ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains. Proc Natl Acad Sci U S A (1990) 4.11

A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain. Genes Dev (1995) 4.11

Stat3 activation is required for cellular transformation by v-src. Mol Cell Biol (1998) 4.09

A transcriptional hierarchy involved in mammalian cell-type specification. Nature (1992) 4.08

Biogenesis of mRNA: genetic regulation in mammalian cells. Science (1973) 4.01

Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head. Genes Dev (1991) 4.01

Evidence that all messenger RNA molecules (except histone messenger RNA) contain Poly (A) sequences and that the Poly(A) has a nuclear function. J Mol Biol (1972) 3.93

Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins. Mol Cell Biol (1992) 3.90

Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell (1998) 3.79

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos. Genes Dev (1994) 3.76

The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction. Proc Natl Acad Sci U S A (1992) 3.74

Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins. Nature (1993) 3.73

The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo. Cell (1994) 3.71

Production of mRNA in Chinese hamster cells: relationship of the rate of synthesis to the cytoplasmic concentration of nine specific mRNA sequences. Cell (1979) 3.67

Reduction of N2O by biological N2-fixing systems. Biochem Biophys Res Commun (1966) 3.66

Transcriptional induction by interferon. New protein(s) determine the extent and length of the induction. J Biol Chem (1986) 3.63

Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma. Proc Natl Acad Sci U S A (1996) 3.62

HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally. Genes Dev (1990) 3.50

Structural difference between the 5' termini of viral and cellular mRNA in poliovirus-infected cells: possible basis for the inhibition of host protein synthesis. J Virol (1976) 3.46

The decrease in size and synthetic activity of poliovirus polysomes late in the infectious cycle. Virology (1967) 3.41

Competition hybridization by "pre-saturation" of HeLa cell DNA. J Mol Biol (1969) 3.40

Implications of RNA-RNA splicing in evolution of eukaryotic cells. Science (1978) 3.39

The turnover of nuclear DNA-like RNA in HeLa cells. J Cell Biol (1968) 3.39

A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene. Proc Natl Acad Sci U S A (1987) 3.38

Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4. J Exp Med (1995) 3.37

The definition of a large viral transcription unit late in Ad2 infection of HeLa cells: mapping of nascent RNA molecules labeled in isolated nuclei. Cell (1977) 3.32

Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to the promoters of both beta interferon- and interferon-stimulated genes but is not a primary transcriptional activator of either. Mol Cell Biol (1990) 3.31

Cytoplasmic activation of GAF, an IFN-gamma-regulated DNA-binding factor. EMBO J (1991) 3.28

Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling. Proc Natl Acad Sci U S A (1996) 3.26

Effect of adenovirus on metabolism of specific host mRNAs: transport control and specific translational discrimination. Mol Cell Biol (1983) 3.25

Rapidly labeled HeLa cell nuclear RNA. II. Base composition and cellular localization of a heterogeneous RNA fraction. J Mol Biol (1966) 3.22

Double-stranded regions in heterogeneous nuclear RNA from Hela cells. Proc Natl Acad Sci U S A (1972) 3.21

Biogenesis and characterization of histone messenger RNA in HeLa cells. J Mol Biol (1972) 3.14

Polyadenylic acid segment in mRNA becomes shorter with age. Nat New Biol (1973) 3.09

Early Ad-2 transcription units: only promoter-proximal RNA continues to be made in the presence of DRB. Virology (1979) 3.06

SV40-specific RNA in the nucleus and polyribosomes of transformed cells. Proc Natl Acad Sci U S A (1970) 3.05

Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport. Mol Cell Biol (1985) 3.04

Methylated, blocked 5 termini in HeLa cell mRNA. Proc Natl Acad Sci U S A (1975) 3.02

Changes in liver-specific compared to common gene transcription during primary culture of mouse hepatocytes. Mol Cell Biol (1983) 3.01

Interferon-stimulated transcription: isolation of an inducible gene and identification of its regulatory region. Proc Natl Acad Sci U S A (1986) 2.92

Regulation of the primary expression of the early adenovirus transcription units. J Virol (1979) 2.92

Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity. Proc Natl Acad Sci U S A (1995) 2.92

Identification of a Stat gene that functions in Drosophila development. Cell (1996) 2.90

Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst. Proc Natl Acad Sci U S A (1994) 2.85

Stat3 and Stat4: members of the family of signal transducers and activators of transcription. Proc Natl Acad Sci U S A (1994) 2.81

Human fibroblast interferon: amino acid analysis and amino terminal amino acid sequence. Science (1980) 2.77

Synergistic interaction between interferon-alpha and interferon-gamma through induced synthesis of one subunit of the transcription factor ISGF3. EMBO J (1990) 2.75

Globin RNA transcription: a possible termination site and demonstration of transcriptional control correlated with altered chromatin structure. Cell (1982) 2.72

Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells. Mol Cell Biol (1992) 2.72

Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons. Mol Cell Biol (1991) 2.71

Processing of adenovirus specific nuclear RNA during virus replication. Virology (1972) 2.71

A liver-specific DNA-binding protein recognizes multiple nucleotide sites in regulatory regions of transthyretin, alpha 1-antitrypsin, albumin, and simian virus 40 genes. Proc Natl Acad Sci U S A (1988) 2.71

The effects of methionine deprivation on ribosome synthesis in HeLa cells. Proc Natl Acad Sci U S A (1967) 2.66

Further evidence on the nuclear origin and transfer to the cytoplasm of polyadenylic acid sequences in mammalian cell RNA. J Mol Biol (1973) 2.61

The inhibition by DRB (5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole) of hnRNA and mRNA production in HeLa cells. Cell (1976) 2.60

Two interferon-induced nuclear factors bind a single promoter element in interferon-stimulated genes. Proc Natl Acad Sci U S A (1988) 2.58

The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase. EMBO J (1996) 2.50

Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function. Proc Natl Acad Sci U S A (1993) 2.47