Characterization of the metabolic turnover of epidermal growth factor receptor protein in A-431 cells.

PubWeight™: 1.04‹?› | Rank: Top 15%

🔗 View Article (PMID 6086681)

Published in J Cell Physiol on September 01, 1984

Authors

C M Stoscheck, G Carpenter

Articles citing this

Endocytosis and intracellular trafficking of ErbBs. Exp Cell Res (2008) 1.96

Endocytosis of receptor tyrosine kinases. Cold Spring Harb Perspect Biol (2013) 1.57

Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor. J Cell Biol (1991) 1.38

Direct visualization of the phosphorylated epidermal growth factor receptor during its internalization in A-431 cells. J Cell Biol (1987) 1.19

Consumption of EGF by A431 cells: evidence for receptor recycling. J Cell Biol (1993) 1.13

Recycling of epidermal growth factor-receptor complexes in A431 cells: identification of dual pathways. J Cell Biol (1991) 1.12

Annexin VI-mediated loss of spectrin during coated pit budding is coupled to delivery of LDL to lysosomes. J Cell Biol (1998) 1.09

Kinetics and regulation of the tyrosine phosphorylation of epidermal growth factor receptor in intact A431 cells. Mol Cell Biol (1988) 1.04

RNA interference screen identifies Usp18 as a regulator of epidermal growth factor receptor synthesis. Mol Biol Cell (2009) 1.03

A431 cell variants lacking the blood group A antigen display increased high affinity epidermal growth factor-receptor number, protein-tyrosine kinase activity, and receptor turnover. J Cell Biol (1988) 1.01

Activation of EGFR, HER2 and HER3 by neurotensin/neurotensin receptor 1 renders breast tumors aggressive yet highly responsive to lapatinib and metformin in mice. Oncotarget (2014) 0.91

Spatial regulation of epidermal growth factor receptor signaling by endocytosis. Int J Mol Sci (2012) 0.83

A novel pulse-chase SILAC strategy measures changes in protein decay and synthesis rates induced by perturbation of proteostasis with an Hsp90 inhibitor. PLoS One (2013) 0.82

UNC50 prompts G1/S transition and proliferation in HCC by regulation of epidermal growth factor receptor trafficking. PLoS One (2015) 0.78

Effects of Activating Mutations on EGFR Cellular Protein Turnover and Amino Acid Recycling Determined Using SILAC Mass Spectrometry. Int J Cell Biol (2015) 0.75

Articles by these authors

Epidermal growth factor. Annu Rev Biochem (1979) 11.82

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts. J Cell Biol (1976) 10.88

Receptors for epidermal growth factor and other polypeptide mitogens. Annu Rev Biochem (1987) 5.57

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity. J Biol Chem (1980) 5.19

Quantitation of protein. Methods Enzymol (1990) 5.00

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase. Science (2001) 4.90

Increase of the catalytic activity of phospholipase C-gamma 1 by tyrosine phosphorylation. Science (1990) 4.36

Human epidermal growth factor and the proliferation of human fibroblasts. J Cell Physiol (1976) 3.91

Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro. Nature (1978) 3.54

Characterization of the binding of 125-I-labeled epidermal growth factor to human fibroblasts. J Biol Chem (1975) 3.48

Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor. J Biol Chem (1979) 3.18

Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalization and extracellular calcium. Proc Natl Acad Sci U S A (1989) 3.17

Human epidermal growth factor: isolation and chemical and biological properties. Proc Natl Acad Sci U S A (1975) 2.95

All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired. J Biol Chem (1996) 2.84

Platelet-derived growth factor induces rapid and sustained tyrosine phosphorylation of phospholipase C-gamma in quiescent BALB/c 3T3 cells. Mol Cell Biol (1989) 2.78

Antiphosphotyrosine recovery of phospholipase C activity after EGF treatment of A-431 cells. Science (1988) 2.62

Interaction of activated EGF receptors with coated pit adaptins. Science (1993) 2.42

Down regulation of epidermal growth factor receptors: direct demonstration of receptor degradation in human fibroblasts. J Cell Biol (1984) 2.12

Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and development. Proc Natl Acad Sci U S A (1997) 1.90

Acrocephaly, with other Congenital Malformations-Autopsy. Proc R Soc Med (1909) 1.89

Interaction of epidermal growth factor (EGF) with cultured fibroblasts. Adv Metab Disord (1975) 1.88

Elevated content of the tyrosine kinase substrate phospholipase C-gamma 1 in primary human breast carcinomas. Proc Natl Acad Sci U S A (1991) 1.77

Tyrosine residues in bovine phospholipase C-gamma phosphorylated by the epidermal growth factor receptor in vitro. J Biol Chem (1990) 1.75

Glycosylation of the epidermal growth factor receptor in A-431 cells. The contribution of carbohydrate to receptor function. J Biol Chem (1984) 1.62

Multiple autophosphorylation sites of the epidermal growth factor receptor are essential for receptor kinase activity and internalization. Contrasting significance of tyrosine 992 in the native and truncated receptors. J Biol Chem (1992) 1.61

Transforming growth factor alpha and beta expression in human colon cancer lines: implications for an autocrine model. Cancer Res (1987) 1.61

Tyrosine phosphorylation of phospholipase C-II in vitro by the epidermal growth factor receptor. J Biol Chem (1989) 1.60

Stoichiometric interaction of the epidermal growth factor receptor with the clathrin-associated protein complex AP-2. J Biol Chem (1995) 1.57

Effect of enteral and parenteral feeding in malnourished rats with E. coli-hemoglobin adjuvant peritonitis. J Surg Res (1981) 1.57

Altered [125I]epidermal growth factor binding and receptor distribution in psoriasis. J Invest Dermatol (1986) 1.56

Congenital Morbus cordis-Patent Ductus arteriosus; Aortic Valves Bicuspid; Right Heart dwarfed. Proc R Soc Med (1909) 1.56

Antibodies to the epidermal growth factor receptor block the biological activities of sarcoma growth factor. Proc Natl Acad Sci U S A (1983) 1.48

Electrophoretic variation in adenylate kinase of Neisseria meningitidis is due to inter- and intraspecies recombination. Proc Natl Acad Sci U S A (1995) 1.48

Enteral and parenteral feeding influences mortality after hemoglobin-E. coli peritonitis in normal rats. J Trauma (1983) 1.47

Identification of two epidermal growth factor-sensitive tyrosine phosphorylation sites of phospholipase C-gamma in intact HSC-1 cells. J Biol Chem (1990) 1.47

Mapping of the molecular determinants involved in the interaction between eps15 and AP-2. Cancer Res (1997) 1.46

Focal adhesion kinase promotes phospholipase C-gamma1 activity. Proc Natl Acad Sci U S A (1999) 1.46

The carboxyl terminus of epidermal growth factor receptor/erbB-2 chimerae is internalization impaired. Oncogene (1993) 1.44

The role of individual SH2 domains in mediating association of phospholipase C-gamma1 with the activated EGF receptor. J Biol Chem (1999) 1.43

Feedback regulation of phospholipase C-beta by protein kinase C. J Biol Chem (1990) 1.41

Role of epidermal growth factor in carcinogenesis. Cancer Res (1986) 1.41

Regulation of epidermal growth factor-stimulated formation of inositol phosphates in A-431 cells by calcium and protein kinase C. J Biol Chem (1988) 1.41

Patient-validated content of epilepsy-specific quality-of-life measurement. Epilepsia (1997) 1.41

Constitutive expression of insulin-like growth factor 1 and insulin-like growth factor 1 receptor abrogates all requirements for exogenous growth factors. Cell Growth Differ (1992) 1.41

Vocal cord dysfunction during wartime. Mil Med (1992) 1.39

Selective cleavage of the heregulin receptor ErbB-4 by protein kinase C activation. J Biol Chem (1996) 1.36

Epidermal growth factor is a major growth-promoting agent in human milk. Science (1980) 1.35

Multiple autophosphorylation site mutations of the epidermal growth factor receptor. Analysis of kinase activity and endocytosis. J Biol Chem (1991) 1.34

Characterization by electrophoresis of epidermal growth factor stimulated phosphorylation using A-431 membranes. Biochemistry (1980) 1.31

Stimulation of phospholipase C-gamma 1 membrane association by epidermal growth factor. Science (1990) 1.29

Growth factor stimulation of phospholipase C-gamma 1 activity. Comparative properties of control and activated enzymes. J Biol Chem (1992) 1.28

Letter: Chloramphenicol eye-drops and marrow aplasia. Lancet (1975) 1.27

Epidermal growth factor, its receptor, and related proteins. Exp Cell Res (1986) 1.27

Physiological requirement for both SH2 domains for phospholipase C-gamma1 function and interaction with platelet-derived growth factor receptors. Mol Cell Biol (1999) 1.26

Epidermal growth factor activation of NF-kappaB is mediated through IkappaBalpha degradation and intracellular free calcium. Oncogene (1998) 1.24

Properties of the receptor for epidermal growth factor. Cell (1984) 1.23

Immunolocalization of epidermal growth factor receptors in normal developing human skin. J Invest Dermatol (1990) 1.23

Disruption of the interaction of mammalian protein synthesis eukaryotic initiation factor 4B with the poly(A)-binding protein by caspase- and viral protease-mediated cleavages. J Biol Chem (2001) 1.22

Individual epidermal growth factor receptor autophosphorylation sites do not stringently define association motifs for several SH2-containing proteins. J Biol Chem (1994) 1.22

Geldanamycin induces ErbB-2 degradation by proteolytic fragmentation. J Biol Chem (2000) 1.22

Production and characterization of antibody blocking epidermal growth factor:receptor interactions. Biochim Biophys Acta (1980) 1.21

Epidermal growth factor (EGF) stimulates inositol trisphosphate formation in cells which overexpress the EGF receptor. Biochem Biophys Res Commun (1987) 1.20

Constitutive proteolysis of the ErbB-4 receptor tyrosine kinase by a unique, sequential mechanism. J Cell Biol (1997) 1.20

Heregulin-dependent trafficking and cleavage of ErbB-4. J Biol Chem (2000) 1.18

Dimerization of internalized epidermal growth factor receptors. J Biol Chem (1991) 1.18

The biochemistry and physiology of the receptor-kinase for epidermal growth factor. Mol Cell Endocrinol (1983) 1.17

The ErbB-4 s80 intracellular domain is a constitutively active tyrosine kinase. Oncogene (2006) 1.16

Characteristics of antibodies to the epidermal growth factor receptor-kinase. Arch Biochem Biophys (1983) 1.16

Interspecies recombination in nature: a meningococcus that has acquired a gonococcal PIB porin. Mol Microbiol (1995) 1.15

Oxidative stress-induced phospholipase C-gamma 1 activation enhances cell survival. J Biol Chem (2001) 1.15

Comparison of epidermal growth factor binding and receptor distribution in normal human epidermis and epidermal appendages. J Invest Dermatol (1984) 1.14

The oligosaccharide moieties of the epidermal growth factor receptor in A-431 cells. Presence of complex-type N-linked chains that contain terminal N-acetylgalactosamine residues. J Biol Chem (1985) 1.13

Epidermal growth factor receptor: elements of intracellular communication. J Membr Biol (1992) 1.13

EGF receptor antiserum inhibits bone resorbing activity produced by a rat Leydig cell tumor associated with the humoral hypercalcemia of malignancy. Endocrinology (1985) 1.11

Influence of lectins on the binding of 125I-labeled EGF to human fibroblasts. Biochem Biophys Res Commun (1977) 1.09

SH2 domain-mediated activation of phospholipase Cgamma is not required to initiate Ca2+ release at fertilization of mouse eggs. Dev Biol (1998) 1.08

The regulation of phospholipase C-gamma 1 by phosphatidic acid. Assessment of kinetic parameters. J Biol Chem (1993) 1.08

Elimination of new chronic hepatitis B virus infections: results of the Alaska immunization program. J Infect Dis (2000) 1.06

Functional and structural characteristics of EGF and its receptor and their relationship to transforming proteins. J Cell Biochem (1986) 1.06

The regulation of cell proliferation: advances in the biology and mechanism of action of epidermal growth factor. J Invest Dermatol (1978) 1.06

The EGF/TGF alpha receptor in skin. J Invest Dermatol (1990) 1.06

Heregulin degradation in the absence of rapid receptor-mediated internalization. Exp Cell Res (1997) 1.05

Protein assay sensitive at nanogram levels. Anal Biochem (1987) 1.05

Rate constants for binding, dissociation, and internalization of EGF: effect of receptor occupancy and ligand concentration. Biochemistry (1990) 1.04

Epidermal growth factor signaling and mitogenesis in Plcg1 null mouse embryonic fibroblasts. Mol Biol Cell (1998) 1.04

Interaction of the adaptor protein Shc and the adhesion molecule cadherin. J Biol Chem (1997) 1.03

Epidermal growth factor/transforming growth factor alpha receptors and psoriasis. J Invest Dermatol (1990) 1.01

Solubilization of membrane receptor for epidermal growth factor. Life Sci (1979) 1.01

Phospholipase C-gamma1: regulation of enzyme function and role in growth factor-dependent signal transduction. Cytokine Growth Factor Rev (1997) 1.00

Analysis of the influences of the E5 transforming protein on kinetic parameters of epidermal growth factor binding and metabolism. J Cell Physiol (1992) 0.99

Tyrosine phosphorylation of ras GTPase-activating protein does not require association with the epidermal growth factor receptor. J Biol Chem (1993) 0.99

Biology of the A-431 cell: a useful organism for hormone research. J Cell Biochem (1983) 0.98

Localization of immunoreactive epidermal growth factor receptors in human nervous system. J Histochem Cytochem (1988) 0.98

Binding assays for epidermal growth factor. Methods Enzymol (1985) 0.98

Selective phospholipase C activation. Bioessays (1991) 0.97

Polysomnographic findings in recently drug-free and clinically remitted depressed patients. Arch Gen Psychiatry (1986) 0.97