Published in Proc Natl Acad Sci U S A on October 01, 1984
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The detection of linkage disequilibrium between closely linked markers: RFLPs at the AI-CIII apolipoprotein genes. Am J Hum Genet (1988) 2.85
Linkage disequilibrium predicts physical distance in the adenomatous polyposis coli region. Am J Hum Genet (1994) 2.65
A deductive method of haplotype analysis in pedigrees. Am J Hum Genet (1987) 2.31
Analysis of the human alpha-globin gene cluster reveals a highly informative genetic locus. Proc Natl Acad Sci U S A (1986) 2.26
Linkage disequilibrium in the neurofibromatosis 1 (NF1) region: implications for gene mapping. Am J Hum Genet (1993) 1.83
Polymorphic DNA haplotypes at the LDL receptor locus. Am J Hum Genet (1989) 1.82
Alternative bioassays of kinship between loci. Am J Hum Genet (1988) 1.66
Molecular genetic approach to human meningioma: loss of genes on chromosome 22. Proc Natl Acad Sci U S A (1987) 1.63
Multiple restriction fragment length polymorphisms at the insulin receptor locus: a highly informative marker for linkage analysis. Proc Natl Acad Sci U S A (1986) 1.59
Linkage disequilibrium of plasminogen polymorphisms and assignment of the gene to human chromosome 6q26-6q27. Am J Hum Genet (1987) 1.43
Polymorphic DNA haplotypes at the phenylalanine hydroxylase (PAH) locus in European families with phenylketonuria (PKU). Am J Hum Genet (1989) 1.41
The use of restriction fragment length polymorphisms in paternity analysis. Am J Hum Genet (1986) 1.36
A strategy for using multiple linked markers for genetic counseling. Am J Hum Genet (1985) 1.08
Structure, evolution, and polymorphisms of the human apolipoprotein A4 gene (APOA4). Proc Natl Acad Sci U S A (1986) 1.00
Haplotypes of the coagulation factor XIII A subunit locus in normal and deficient subjects. Am J Hum Genet (1988) 1.00
Extensive DNA polymorphism at the factor XIIIa (F13A) locus and linkage to HLA. Am J Hum Genet (1988) 0.99
Genes encoding pancreatic polypeptide and neuropeptide Y are on human chromosomes 17 and 7. J Clin Invest (1986) 0.96
The unique endocrine milieu of the fetus. J Clin Invest (1986) 0.87
Chromosomal localization and racial distribution of the polymorphic human dihydrofolate reductase pseudogene (DHFRP1). Am J Hum Genet (1988) 0.84
Linkage disequilibrium of evolutionarily conserved regions in the human genome. BMC Genomics (2006) 0.81
A linkage map of three anonymous human DNA fragments and SOD-1 on chromosome 21. EMBO J (1985) 0.79
SphI RFLP at the human growth hormone gene cluster. Nucleic Acids Res (1992) 0.75
Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants. Proc Natl Acad Sci U S A (1977) 13.87
DNA polymorphism detectable by restriction endonucleases. Genetics (1981) 10.13
Estimation of genetic variation at the DNA level from restriction endonuclease data. Proc Natl Acad Sci U S A (1981) 4.71
The age of a neutral mutant persisting in a finite population. Genetics (1973) 4.44
The estimation of gene frequencies in a random-mating population. Ann Hum Genet (1955) 4.06
Human growth hormone: complementary DNA cloning and expression in bacteria. Science (1979) 3.67
Genic variation within and between the three major races of man, Caucasoids, Negroids, and Mongoloids. Am J Hum Genet (1974) 2.77
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Genes for growth hormone, chorionic somatommammotropin, and growth hormones-like gene on chromosome 17 in humans. Science (1980) 1.85
The human growth hormone gene family: structure and evolution of the chromosomal locus. Nucleic Acids Res (1983) 1.81
Prenatal diagnosis of human genome variation. Annu Rev Genet (1979) 1.73
Structure of genes for human growth hormone and chorionic somatomammotropin. Proc Natl Acad Sci U S A (1979) 1.71
Genetic analysis of familial isolated growth hormone deficiency type I. J Clin Invest (1982) 1.36
A gene deletion is responsible for absence of human chorionic somatomammotropin. DNA (1982) 1.10
A system for shotgun DNA sequencing. Nucleic Acids Res (1981) 52.99
Supercoil sequencing: a fast and simple method for sequencing plasmid DNA. DNA (1985) 40.01
Identification of the cystic fibrosis gene: genetic analysis. Science (1989) 33.61
Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. Nat Genet (1999) 17.09
Comparative analyses of multi-species sequences from targeted genomic regions. Nature (2003) 13.31
Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature (1985) 13.04
Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron (1994) 11.44
Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue. Nature (1983) 10.64
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science (1985) 9.12
Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science (1995) 8.61
New goals for the U.S. Human Genome Project: 1998-2003. Science (1998) 8.30
Nonuniform recombination within the human beta-globin gene cluster. Am J Hum Genet (1984) 7.97
Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone. Nature (1977) 7.97
DNA duplication associated with Charcot-Marie-Tooth disease type 1A. Cell (1991) 7.93
A DNA polymorphism discovery resource for research on human genetic variation. Genome Res (1998) 7.44
The primary structure and genetic organization of the bovine papillomavirus type 1 genome. Nature (1982) 7.24
Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension. Nat Genet (2000) 7.20
RNA editing in brain controls a determinant of ion flow in glutamate-gated channels. Cell (1991) 6.97
Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2. Nature (2000) 6.67
Beta-globin locus is linked to the parathyroid hormone (PTH) locus and lies between the insulin and PTH loci in man. Proc Natl Acad Sci U S A (1983) 6.50
Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science (1992) 6.49
Biological properties of human c-Ha-ras1 genes mutated at codon 12. Nature (1984) 6.21
Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene. Nature (1983) 5.90
Human leukocyte interferon produced by E. coli is biologically active. Nature (1980) 5.86
RNA editing of AMPA receptor subunit GluR-B: a base-paired intron-exon structure determines position and efficiency. Cell (1993) 5.62
Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli. Nature (1983) 5.27
High-throughput variation detection and genotyping using microarrays. Genome Res (2001) 5.24
Control of kinetic properties of AMPA receptor channels by nuclear RNA editing. Science (1994) 5.21
The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. J Neurosci (1992) 5.02
Tripartite structure of the avian erythroblastosis virus E26 transforming gene. Nature (1984) 4.99
Interaction of RNA polymerase with promoters from bacteriophage fd. Eur J Biochem (1977) 4.94
Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning. Science (1999) 4.56
Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit. Neuron (1992) 4.53
The structure of eight distinct cloned human leukocyte interferon cDNAs. Nature (1981) 4.50
The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development. J Neurosci (1992) 4.45
Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology. Nature (1989) 4.45
Expression of active human factor VIII from recombinant DNA clones. Nature (1984) 4.36
Vaginal progesterone reduces the rate of preterm birth in women with a sonographic short cervix: a multicenter, randomized, double-blind, placebo-controlled trial. Ultrasound Obstet Gynecol (2011) 4.31
Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS. Neuron (1995) 4.24
Automated construction of genetic linkage maps using an expert system (MultiMap): a human genome linkage map. Nat Genet (1994) 4.19
Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations. Nature (1983) 4.15
Association of genetic variation of the transforming growth factor-alpha gene with cleft lip and palate. Am J Hum Genet (1989) 4.13
Hirschsprung disease, associated syndromes and genetics: a review. J Med Genet (2007) 4.13
A comprehensive human linkage map with centimorgan density. Cooperative Human Linkage Center (CHLC). Science (1994) 4.02
A mammalian RNA editing enzyme. Nature (1996) 3.90
A family of AMPA-selective glutamate receptors. Science (1990) 3.85
Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone. Nature (1979) 3.80
RFLPs for transforming growth factor alpha (TGFA) gene at 2p13. Nucleic Acids Res (1986) 3.72
Recombinant human acid alpha-glucosidase enzyme therapy for infantile glycogen storage disease type II: results of a phase I/II clinical trial. Genet Med (2001) 3.60
Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science (1990) 3.53
A collection of tri- and tetranucleotide repeat markers used to generate high quality, high resolution human genome-wide linkage maps. Hum Mol Genet (1995) 3.44
Differential signal transduction by five splice variants of the PACAP receptor. Nature (1993) 3.38
Basic fallacies in the formulation of the paternity index. Am J Hum Genet (1985) 3.18
Structural determinants of ion flow through recombinant glutamate receptor channels. Science (1991) 3.18
Construction and analysis of recombinant DNA for human chorionic somatomammotropin. Nature (1977) 3.13
Determinants of Ca2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels: diversity by RNA editing. Neuron (1993) 3.08
Lutropin-choriogonadotropin receptor: an unusual member of the G protein-coupled receptor family. Science (1989) 3.03
DNA restriction endonuclease analysis for localization of human beta- and delta-globin genes on chromosome 11. Proc Natl Acad Sci U S A (1979) 3.02
The cancer genome anatomy project: building an annotated gene index. Trends Genet (2000) 3.02
Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21. Nat Genet (1998) 3.00
The sequence of human serum albumin cDNA and its expression in E. coli. Nucleic Acids Res (1981) 2.97
Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA. Nature (1982) 2.96
Evidence for increased recombination near the human insulin gene: implication for disease association studies. Proc Natl Acad Sci U S A (1986) 2.96
Molecular evidence for a relationship between LINE-1 elements and X chromosome inactivation: the Lyon repeat hypothesis. Proc Natl Acad Sci U S A (2000) 2.94
Codon-improved Cre recombinase (iCre) expression in the mouse. Genesis (2002) 2.92
Estimating the prior probability of paternity from the results of exclusion tests. Forensic Sci Int (1984) 2.91
Similarity of DNA fingerprints due to chance and relatedness. Hum Hered (1993) 2.90
Parallel genotyping of human SNPs using generic high-density oligonucleotide tag arrays. Genome Res (2000) 2.79
Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice. Science (1995) 2.78
Genetic mapping of autosomal dominant Charcot-Marie-Tooth disease in a large French-Acadian kindred: identification of new linked markers on chromosome 17. Am J Hum Genet (1990) 2.77
The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor. EMBO J (1984) 2.77
Functional properties of recombinant rat GABAA receptors depend upon subunit composition. Neuron (1990) 2.75
The primary structure of the Saccharomyces cerevisiae gene for 3-phosphoglycerate kinase. Nucleic Acids Res (1982) 2.67
Differences in Ca2+ permeability of AMPA-type glutamate receptor channels in neocortical neurons caused by differential GluR-B subunit expression. Neuron (1994) 2.67
Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor. Science (1992) 2.64
RED2, a brain-specific member of the RNA-specific adenosine deaminase family. J Biol Chem (1996) 2.64
Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+. Neuron (1990) 2.60
cDNA cloning of human liver monoamine oxidase A and B: molecular basis of differences in enzymatic properties. Proc Natl Acad Sci U S A (1988) 2.59
Regulated expression of human growth hormone genes in mouse cells. Cell (1982) 2.58
BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension. Am J Hum Genet (2000) 2.51
A standardized nomenclature for adenosine deaminases that act on RNA. RNA (1997) 2.50
Cerebellar GABAA receptor selective for a behavioural alcohol antagonist. Nature (1990) 2.50
The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum. J Neurosci (1992) 2.48
The human pro-opiomelanocortin gene: organization, sequence, and interspersion with repetitive DNA. DNA (1982) 2.47
Regulation of growth hormone messenger RNA by thyroid and glucocorticoid hormones. Proc Natl Acad Sci U S A (1977) 2.47
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Mutation in the gene for bone morphogenetic protein receptor II as a cause of primary pulmonary hypertension in a large kindred. N Engl J Med (2001) 2.45
Neurosteroids act on recombinant human GABAA receptors. Neuron (1990) 2.44
Detection of Pseudomonas (Burkholderia) cepacia using PCR. Pediatr Pulmonol (1995) 2.44
A molecular determinant for submillisecond desensitization in glutamate receptors. Science (1994) 2.43
Spatial memory dissociations in mice lacking GluR1. Nat Neurosci (2002) 2.39
Two novel GABAA receptor subunits exist in distinct neuronal subpopulations. Neuron (1989) 2.38
Patterns of genetic variation in Mendelian and complex traits. Annu Rev Genomics Hum Genet (2000) 2.37
Interaction of ion channels and receptors with PDZ domain proteins. Curr Opin Neurobiol (1997) 2.37
Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression. Int J Cancer (1998) 2.36
Amino acid sequence of the alpha subunit of transducin deduced from the cDNA sequence. Proc Natl Acad Sci U S A (1985) 2.34
Saccharomyces cerevisiae contains two discrete genes coding for the alpha-factor pheromone. Nucleic Acids Res (1983) 2.34
Clinical and epidemiologic studies of cleft lip and palate in the Philippines. Cleft Palate Craniofac J (1997) 2.33
The human growth hormone gene family: nucleotide sequences show recent divergence and predict a new polypeptide hormone. DNA (1982) 2.32